BRPI1010950A2 - método para preparação de emulsão carregada de fármaco. - Google Patents

método para preparação de emulsão carregada de fármaco.

Info

Publication number
BRPI1010950A2
BRPI1010950A2 BRPI1010950A BRPI1010950A BRPI1010950A2 BR PI1010950 A2 BRPI1010950 A2 BR PI1010950A2 BR PI1010950 A BRPI1010950 A BR PI1010950A BR PI1010950 A BRPI1010950 A BR PI1010950A BR PI1010950 A2 BRPI1010950 A2 BR PI1010950A2
Authority
BR
Brazil
Prior art keywords
drug loaded
preparing drug
loaded emulsion
emulsion
preparing
Prior art date
Application number
BRPI1010950A
Other languages
English (en)
Inventor
Wang Halfeng
Yu Li
Chen Liang
Tong Xinyong
Shi Yuan
Original Assignee
Jiangsu Hengrui Medicine Co
Shanghai hengrui pharmaceutical co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jiangsu Hengrui Medicine Co, Shanghai hengrui pharmaceutical co ltd filed Critical Jiangsu Hengrui Medicine Co
Publication of BRPI1010950A2 publication Critical patent/BRPI1010950A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Psychiatry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Nutrition Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BRPI1010950A 2009-06-04 2010-06-03 método para preparação de emulsão carregada de fármaco. BRPI1010950A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2009100525352A CN101904814A (zh) 2009-06-04 2009-06-04 制备载药乳剂的方法
PCT/CN2010/073500 WO2010139278A1 (zh) 2009-06-04 2010-06-03 制备载药乳剂的方法

Publications (1)

Publication Number Publication Date
BRPI1010950A2 true BRPI1010950A2 (pt) 2018-03-06

Family

ID=43260505

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1010950A BRPI1010950A2 (pt) 2009-06-04 2010-06-03 método para preparação de emulsão carregada de fármaco.

Country Status (10)

Country Link
US (1) US20120177699A1 (pt)
EP (1) EP2438909A1 (pt)
JP (1) JP2012528804A (pt)
KR (1) KR20120027298A (pt)
CN (2) CN101904814A (pt)
AU (1) AU2010256130A1 (pt)
BR (1) BRPI1010950A2 (pt)
CA (1) CA2762918A1 (pt)
MX (1) MX2011012884A (pt)
WO (1) WO2010139278A1 (pt)

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CN102600077B (zh) * 2012-03-29 2013-06-05 江苏豪森药业股份有限公司 吉西他滨或其盐纳米乳剂注射液及其制备方法
JP6121796B2 (ja) * 2012-05-23 2017-04-26 キユーピー株式会社 脂肪乳剤および医薬品組成物中の非ステロイド性抗炎症薬の含有量を高める方法
CN102793730B (zh) * 2012-08-31 2013-11-06 山西普德药业股份有限公司 银杏达莫的药物组合物及其制备方法
CN102988285B (zh) * 2012-12-13 2014-02-19 哈药集团技术中心 一种多西他赛注射液组合物及其制备方法
GB2511028A (en) * 2012-12-18 2014-08-27 Univ Manchester Metropolitan Nano emulsions, methods of forming the same and uses thereof
KR101586790B1 (ko) 2012-12-28 2016-01-19 주식회사 종근당 음이온성 약리학적 활성물질의 서방성 지질 초기제제 및 이를 포함하는 약제학적 조성물
CN103961314A (zh) * 2013-01-24 2014-08-06 上海医药工业研究院 一种稳定的麻醉乳剂
KR101498274B1 (ko) * 2013-01-30 2015-03-11 재단법인 전남생물산업진흥원 편백 정유 에멀젼의 제조방법
CN104706587A (zh) * 2013-12-16 2015-06-17 天津迈迪瑞康生物医药科技有限公司 一种依托咪酯脂肪乳浓缩液、其制备方法及用途
CN103750050B (zh) * 2014-01-21 2016-07-06 武汉轻工大学 棕榈油纳米乳液的制备方法
SG11201701292XA (en) * 2014-08-27 2017-03-30 Abbvie Inc Topical formulation
CN105816465A (zh) * 2015-01-08 2016-08-03 辽宁医联新药研究所 丙泊酚与地西泮药物组合物及其应用
CN104606135A (zh) * 2015-01-22 2015-05-13 李宏 一种含多西他赛的组合物及其制备方法
CN104644554B (zh) * 2015-03-05 2018-03-16 北京蓝丹医药科技有限公司 一种依托咪酯药物组合物及其制备方法
CN105055310B (zh) * 2015-08-30 2018-03-09 四川百利药业有限责任公司 一种注射用依托咪酯组合物及其制备方法
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US11780848B2 (en) 2015-10-16 2023-10-10 Abbvie Inc. Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1- carboxamide and solid state forms thereof
US10550126B2 (en) 2015-10-16 2020-02-04 Abbvie Inc. Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-A]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof
US11524964B2 (en) 2015-10-16 2022-12-13 Abbvie Inc. Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof
SG10201913999PA (en) 2015-10-16 2020-03-30 Abbvie Inc PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-a]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF
US11365198B2 (en) 2015-10-16 2022-06-21 Abbvie Inc. Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof
US12365689B2 (en) 2015-10-16 2025-07-22 Abbvie Inc. Processes for the preparation of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]-pyrazin-8-yl)-n-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide and solid state forms thereof
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BR112018070960A2 (pt) * 2016-04-13 2019-01-29 Nortic Holdings Inc. formulação parenteral de nimodipina estável
CN110496101A (zh) * 2016-06-24 2019-11-26 广东双骏生物科技有限公司 一种稳定型维生素k2亚微乳及其制备方法
CN106070660A (zh) * 2016-07-09 2016-11-09 东北农业大学 一种水酶法提取大豆纳米乳状液的方法
WO2018064350A1 (en) * 2016-09-30 2018-04-05 Eriochem Usa, Llc Apo-e modified lipid nanoparticles for drug delivery to targeted tissues and therapeutic methods
CN108096408A (zh) * 2016-11-17 2018-06-01 中国科学院大连化学物理研究所 一种鼻用喷雾剂及其制备和应用
WO2018164121A1 (ja) * 2017-03-06 2018-09-13 丸石製薬株式会社 局所麻酔薬含有酸性エマルション組成物
US11564922B2 (en) 2017-03-09 2023-01-31 Abbvie Inc. Methods of treating crohn's disease and ulcerative colitis
TWI851536B (zh) 2017-03-09 2024-08-11 美商艾伯維有限公司 治療克羅恩氏病和潰瘍性結腸炎之方法
JP2021513995A (ja) * 2018-02-22 2021-06-03 ノーティック ホールディングス インコーポレイテッド 安定したニモジピン非経口製剤
US20190307892A1 (en) * 2018-04-04 2019-10-10 Eriochem Usa, Llc Targeted drug delivery and therapeutic methods using apo-e modified lipid nanoparticles
CN108743952B (zh) * 2018-06-11 2021-08-31 西安力邦医药科技有限责任公司 局部麻醉药的磷脂-混溶剂-油缓释递药系统组方与制备方法
CN108553414A (zh) * 2018-06-19 2018-09-21 吉林百年汉克制药有限公司 一种人参糖肽注射液药物组合物及其制备方法和应用
CN112912066B (zh) * 2018-09-08 2022-03-29 江苏九旭药业有限公司 一种尼莫地平注射液组合物及其制备方法
CN111840553A (zh) * 2019-04-15 2020-10-30 湖州依诺唯新药物制剂有限公司 脂性药物制剂及其应用
CN111904933B (zh) * 2019-05-08 2023-06-13 北京化工大学 一种透明水分散型达沙替尼纳米乳及其制备方法
CN114099433A (zh) * 2020-09-01 2022-03-01 宜昌人福药业有限责任公司 挥发性麻醉药注射用脂肪乳的制备方法及其组合物
CN114668720A (zh) * 2020-12-24 2022-06-28 远大生命科学(武汉)有限公司 一种依托咪酯乳状注射液及其制备方法
CN112933043B (zh) * 2021-02-24 2022-07-12 石家庄四药有限公司 一种盐酸阿比多尔注射乳剂及其制备方法
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CN113425683B (zh) * 2021-08-19 2022-09-20 谢彩华 一种三氮脒缓释注射剂及其制备方法
CN116196275B (zh) * 2021-11-30 2025-06-20 沈阳药大雷允上药业有限责任公司 制备鸦胆子油乳注射液的方法及其应用
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Also Published As

Publication number Publication date
WO2010139278A1 (zh) 2010-12-09
US20120177699A1 (en) 2012-07-12
KR20120027298A (ko) 2012-03-21
JP2012528804A (ja) 2012-11-15
HK1154502A1 (en) 2012-04-27
CA2762918A1 (en) 2010-12-09
MX2011012884A (es) 2012-01-12
AU2010256130A1 (en) 2012-01-19
EP2438909A1 (en) 2012-04-11
CN102159188B (zh) 2014-07-09
CN102159188A (zh) 2011-08-17
CN101904814A (zh) 2010-12-08

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