BRPI1013560A2 - métodos para auxiliar no prognóstico de doença instestinal inflamatória, e para predizer a probabilidade que um indivíduo diagnosticado com doença intestinal inflamatória responderá a um agente terapêutico de doença intestinal inflamatória - Google Patents

métodos para auxiliar no prognóstico de doença instestinal inflamatória, e para predizer a probabilidade que um indivíduo diagnosticado com doença intestinal inflamatória responderá a um agente terapêutico de doença intestinal inflamatória

Info

Publication number
BRPI1013560A2
BRPI1013560A2 BRPI1013560A BRPI1013560A BRPI1013560A2 BR PI1013560 A2 BRPI1013560 A2 BR PI1013560A2 BR PI1013560 A BRPI1013560 A BR PI1013560A BR PI1013560 A BRPI1013560 A BR PI1013560A BR PI1013560 A2 BRPI1013560 A2 BR PI1013560A2
Authority
BR
Brazil
Prior art keywords
inflammatory bowel
bowel disease
prognosis
predict
likelihood
Prior art date
Application number
BRPI1013560A
Other languages
English (en)
Inventor
Barken Derren
Princen Fred
Eggleston Leonard
Singh Sharat
Original Assignee
Prometheus Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42401087&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI1013560(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Prometheus Laboratories Inc filed Critical Prometheus Laboratories Inc
Publication of BRPI1013560A2 publication Critical patent/BRPI1013560A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/06—Gastro-intestinal diseases
    • G01N2800/065—Bowel diseases, e.g. Crohn, ulcerative colitis, IBS
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/56—Staging of a disease; Further complications associated with the disease
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
BRPI1013560A 2009-04-14 2010-04-13 métodos para auxiliar no prognóstico de doença instestinal inflamatória, e para predizer a probabilidade que um indivíduo diagnosticado com doença intestinal inflamatória responderá a um agente terapêutico de doença intestinal inflamatória BRPI1013560A2 (pt)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US16923009P 2009-04-14 2009-04-14
US17845409P 2009-05-14 2009-05-14
US22045309P 2009-06-25 2009-06-25
US25506609P 2009-10-26 2009-10-26
US26290309P 2009-11-19 2009-11-19
US26532409P 2009-11-30 2009-11-30
US26572309P 2009-12-01 2009-12-01
US28635609P 2009-12-14 2009-12-14
US30078710P 2010-02-02 2010-02-02
US30206610P 2010-02-05 2010-02-05
PCT/US2010/030934 WO2010120814A1 (en) 2009-04-14 2010-04-13 Inflammatory bowel disease prognostics

Publications (1)

Publication Number Publication Date
BRPI1013560A2 true BRPI1013560A2 (pt) 2018-06-19

Family

ID=42401087

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1013560A BRPI1013560A2 (pt) 2009-04-14 2010-04-13 métodos para auxiliar no prognóstico de doença instestinal inflamatória, e para predizer a probabilidade que um indivíduo diagnosticado com doença intestinal inflamatória responderá a um agente terapêutico de doença intestinal inflamatória

Country Status (9)

Country Link
US (1) US9732385B2 (pt)
EP (2) EP2960342A1 (pt)
AU (1) AU2010236568B2 (pt)
BR (1) BRPI1013560A2 (pt)
CA (1) CA2758531C (pt)
ES (1) ES2553415T3 (pt)
IL (2) IL215619A (pt)
NZ (2) NZ595471A (pt)
WO (1) WO2010120814A1 (pt)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11268149B2 (en) 2004-12-08 2022-03-08 Cedars-Sinai Medical Center Diagnosis and treatment of inflammatory bowel disease
US12110555B2 (en) 2004-12-08 2024-10-08 Cedars-Sinai Medical Center Diagnosis and treatment of inflammatory bowel disease
WO2010062960A2 (en) 2008-11-26 2010-06-03 Cedars-Sinai Medical Center METHODS OF DETERMINING RESPONSIVENESS TO ANTI-TNFα THERAPY IN INFLAMMATORY BOWEL DISEASE
NZ595471A (en) 2009-04-14 2014-01-31 Nestec Sa Inflammatory bowel disease prognostics
JP2013528389A (ja) * 2010-06-04 2013-07-11 ネステク ソシエテ アノニム 炎症性腸疾患の診断を改善させる方法
US8645306B2 (en) * 2010-07-02 2014-02-04 Idexx Laboratories, Inc. Automated calibration method and system for a diagnostic analyzer
WO2012071436A1 (en) * 2010-11-24 2012-05-31 Genentech, Inc. Method of treating autoimmune inflammatory disorders using il-23r loss-of-function mutants
CA2830351A1 (en) * 2011-03-25 2012-10-04 Cedars-Sinai Medical Center Methods of diagnosing ulcerative colitis and crohn's disease
EP2689034B1 (en) * 2011-03-25 2016-03-23 Cedars-Sinai Medical Center Role of ifng methylation in inflammatory bowel disease
WO2012154987A1 (en) * 2011-05-10 2012-11-15 Nestec Sa Methods of disease activity profiling for personalized therapy management
WO2012174293A2 (en) * 2011-06-14 2012-12-20 Nestec Sa Methods for identifying inflammatory bowel disease patients with dysplasia or cancer
EP2769321B1 (en) * 2011-10-21 2016-06-01 Nestec S.A. Methods for improving inflammatory bowel disease diagnosis
CN103958662A (zh) * 2011-10-24 2014-07-30 私募蛋白质体公司 用于疾病生物标记鉴定和样品质量评价的优选样品处理和加工方案的选择
EP2907061A4 (en) * 2012-10-10 2016-07-27 Abbvie Biotechnology Ltd MANAGEMENT OF HEALTH SERVICES
RU2517069C1 (ru) * 2012-11-21 2014-05-27 Мария Георгиевна Ильяшенко Способ прогнозирования риска развития рецидива воспалительных заболеваний кишечника
KR20230109779A (ko) 2013-03-27 2023-07-20 세다르스-신나이 메디칼 센터 Tl1a 기능 및 관련된 신호전달 경로의 저해에 의한섬유증 및 염증의 완화 및 반전
USD802608S1 (en) * 2013-04-25 2017-11-14 Life Technologies Corporation Display screen with graphical user interface
CN105209643A (zh) * 2013-05-17 2015-12-30 豪夫迈·罗氏有限公司 用于诊断和治疗炎性肠病的方法
CN105358713B (zh) * 2013-05-17 2020-02-28 雪松-西奈医学中心 与克罗恩病相关的tnfsf15和dcr3的变体
SG11201509371XA (en) 2013-05-24 2015-12-30 Nestec Sa Pathway specific markers for diagnosing irritable bowel syndrome
EP4105236A1 (en) 2013-07-19 2022-12-21 Cedars-Sinai Medical Center Anti-tl1a (tnfsf15) antibody for treatment of inflammatory bowel disease
CA2932571A1 (en) 2013-12-03 2015-06-11 Nestec S.A. Methods for predicting post-operative recurrence of crohn's disease
MA39804A (fr) 2014-03-27 2017-02-01 Hoffmann La Roche Méthodes permettant le diagnostic et le traitement d'une maladie inflammatoire de l'intestin
US10127660B2 (en) * 2015-12-30 2018-11-13 Case Western Reserve University Radiomic features on diagnostic magnetic resonance enterography
US11946927B2 (en) 2016-03-14 2024-04-02 Musidora Biotechnology Llc Process and system for identifying individuals having a high risk of inflammatory bowel disease and a method of treatment
KR20180127416A (ko) 2016-03-17 2018-11-28 세다르스-신나이 메디칼 센터 Rnaset2를 통한 염증성 장 질환의 진단 방법
CN109690314B (zh) * 2016-05-09 2022-08-02 法国国家卫生及研究医学协会 患有实体癌症的患者的分类方法
CN109476698B (zh) 2016-05-20 2023-10-17 西达-赛奈医疗中心 基于基因的炎性肠病诊断
EP3273373A1 (en) * 2016-07-18 2018-01-24 Fresenius Medical Care Deutschland GmbH Drug dosing recommendation
JP6567484B2 (ja) * 2016-09-29 2019-08-28 株式会社日立製作所 推計モデル構築システム、推計モデル構築方法及びプログラム
US20180272065A1 (en) * 2017-03-24 2018-09-27 Medtronic Minimed, Inc. Patient management systems and uplift recommendation methods
US11162943B2 (en) 2017-05-31 2021-11-02 Prometheus Biosciences Inc. Methods for assessing mucosal healing in Crohn's disease patients
US10368502B2 (en) 2017-09-25 2019-08-06 Multiple Energy Technologies Llc Bioceramic and carbon-based hydroponic systems, methods and devices
CN109884310B (zh) * 2017-12-25 2022-04-01 苏州和锐生物科技有限公司 肠道菌外膜多肽、抗体捕获器件及试剂盒
CN109884311B (zh) * 2017-12-25 2022-04-01 苏州和锐生物科技有限公司 肠杆菌多肽、抗体捕获器件及试剂盒
AU2019325238A1 (en) 2018-08-21 2021-03-18 Bruce R. Yacyshyn Process and system for identifying individuals having a high risk of inflammatory bowel disease and a method of treatment
CA3121162A1 (en) 2018-11-29 2020-06-04 Cedars-Sinai Medical Center Rnaset2 compositions and methods of treatment therewith
WO2020205911A1 (en) * 2019-04-01 2020-10-08 Colorado State University Research Foundation Methods for diagnosing and treating inflammatory bowel disease in companion animals
CN114375339A (zh) 2019-05-14 2022-04-19 普罗米修斯生物科学公司 Tl1a患者选择方法、系统和装置
CN120866510A (zh) * 2019-08-12 2025-10-31 雷杰纳荣制药公司 巨噬细胞刺激1受体(mst1r)变体及其用途
US12394524B2 (en) * 2020-07-22 2025-08-19 Iterative Scopes, Inc. Systems and methods for analysis of medical images for scoring of inflammatory bowel disease
CN116973572B (zh) * 2023-06-02 2025-03-07 东南大学附属中大医院 基于血、粪便铁蛋白检测评估肠屏障损伤严重程度的方法

Family Cites Families (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4277250A (en) 1979-12-10 1981-07-07 Baylor College Of Medicine Methods for detecting and quantifying occult blood
JPH0684970B2 (ja) 1987-03-31 1994-10-26 株式会社京都医科学研究所 糞便中の潜血検出方法
US5081040A (en) 1987-06-29 1992-01-14 Helena Laboratories Corporation Composition and kit for testing for occult blood in human and animal excretions, fluids, or tissue matrixes
US6867195B1 (en) 1989-03-21 2005-03-15 Vical Incorporated Lipid-mediated polynucleotide administration to reduce likelihood of subject's becoming infected
JPH0736013B2 (ja) 1991-04-27 1995-04-19 一男 田畑 潜血検出用試薬
US5885527A (en) 1992-05-21 1999-03-23 Biosite Diagnostics, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membrances
US5830675A (en) 1993-03-10 1998-11-03 Cedars-Sinai Medical Center Methods for selectively detecting perinuclear anti-neutrophil cytoplasmic antibody of ulcerative colitis, primary sclerosing cholangitis, or type 1 autoimmune hepatitis
ATE193601T1 (de) 1993-03-10 2000-06-15 Cedars Sinai Medical Center Verfahren zum selektiven nachweis von perinuklearen anti-neutrophilen cytoplasmischen antikörpern bei ulzerativen kolitis oder primärer sclerotischer cholangitis
US5972901A (en) 1994-03-23 1999-10-26 Case Western Reserve University Serpin enzyme complex receptor--mediated gene transfer
US5844107A (en) 1994-03-23 1998-12-01 Case Western Reserve University Compacted nucleic acids and their delivery to cells
CA2186118C (en) 1994-03-23 2010-10-19 Richard W. Hanson Compacted nucleic acids and their delivery to cells
US6077835A (en) 1994-03-23 2000-06-20 Case Western Reserve University Delivery of compacted nucleic acid to cells
US6074835A (en) 1996-04-12 2000-06-13 Regents Of The Univ. Of California Diagnosis, prevention and treatment of ulcerative colitis, and clinical subtypes thereof, using histone H1
US5932429A (en) * 1996-04-12 1999-08-03 Cedars-Sinai Medical Center Methods of diagnosing clinical subtypes of crohn's disease
US6033864A (en) 1996-04-12 2000-03-07 The Regents Of The University Of California Diagnosis, prevention and treatment of ulcerative colitis, and clinical subtypes thereof, using microbial UC pANCA antigens
US5916748A (en) * 1996-04-12 1999-06-29 Cedars-Sinai Medical Center Method of diagnosing a clinical subtype of crohn's disease with features of ulcerative colitis
WO1998037415A1 (en) 1997-02-20 1998-08-27 The Regents Of The University Of California ULCERATIVE COLITIS pANCA SECRETORY VESICLE ANTIGEN AND METHODS OF USING SAME
US6218129B1 (en) 1998-05-15 2001-04-17 Prometheus Laboratories, Inc. Inflammatory bowel disease first step assay system
US6406862B1 (en) 1998-10-06 2002-06-18 The United States Of America As Represented By The Secretary Of The Army Dip-stick assay for C-reactive protein
US6309643B1 (en) 1999-04-30 2001-10-30 The Regents Of The University Of California IBD-associated microbial antigens and methods of using same
WO2000071096A2 (en) 1999-05-24 2000-11-30 Introgen Therapeutics, Inc. Methods and compositions for non-viral gene therapy for treatment of hyperproliferative diseases
FR2802536B1 (fr) 1999-11-23 2003-06-13 Chru Lille Oligomannosides de synthese, leur preparation et leur utilisation a la detection d'anticorps et a la prevention d'infections
FR2806739B1 (fr) * 2000-03-27 2005-02-18 Fond Jean Dausset Ceph Genes impliques dans les maladies inflammatoires de l'intestin et leur utilisation
US6838250B2 (en) 2000-03-31 2005-01-04 Ortho-Clinical Diagnostics, Inc. Immunoassay for C-reactive protein
US7138237B1 (en) 2000-05-19 2006-11-21 Cedars-Sinai Medical Center Diagnosis, prevention and treatment of Crohn's disease using the OmpC antigen
US20020042388A1 (en) 2001-05-01 2002-04-11 Cooper Mark J. Lyophilizable and enhanced compacted nucleic acids
US6821739B2 (en) * 2000-10-13 2004-11-23 The Regents Of The University Of California Methods of diagnosing and treating Crohn's disease using Pseudomonas antigens
WO2002032396A2 (en) 2000-10-16 2002-04-25 Massachusetts Institute Of Technology Lipid-protein-sugar particles for delivery of nucleic acids
AU2002227350B2 (en) 2000-10-30 2007-03-22 Regents Of The University Of Michigan Nod2 nucleic acids and proteins
EP1404712B1 (en) 2000-10-30 2014-06-18 The Regents Of The University Of Michigan Nod2 nucleic acids and proteins
US7060442B2 (en) * 2000-10-30 2006-06-13 Regents Of The University Of Michigan Modulators on Nod2 signaling
US20050164929A1 (en) * 2000-11-06 2005-07-28 Lupine Logic, Inc. Methods of preventing and treating inflammatory bowel disease
EP2071332A1 (en) 2000-11-14 2009-06-17 Techlab, Inc. Method for monitoring persons with IBD using total endogeneous lactoferrin as a marker
AU2002256398A2 (en) 2001-04-30 2002-11-11 Targeted Genetics Corporation Lipid-comprising drug delivery complexes and methods for their production
EP1581119B1 (en) 2001-12-17 2013-01-30 Corixa Corporation Compositions and methods for the therapy and diagnosis of inflammatory bowel disease
US20030204507A1 (en) * 2002-04-25 2003-10-30 Li Jonathan Qiang Classification of rare events with high reliability
US20040053263A1 (en) 2002-08-30 2004-03-18 Abreu Maria T. Mutations in NOD2 are associated with fibrostenosing disease in patients with Crohn's disease
ATE395596T1 (de) 2002-10-25 2008-05-15 Techlab Inc Diagnostisches panel ibd-first chek fur entzundliche darmerkrankung (ibd) und reizkolon
AU2003298703A1 (en) 2002-11-22 2004-06-18 Emory University Diagnostic tests and methods for diagnosing inflammatory bowel disease
US7662569B2 (en) 2003-04-11 2010-02-16 Cedars-Sinai Medical Center Methods of assessing Crohn's disease patient phenotype by I2 serologic response
JPWO2004095021A1 (ja) 2003-04-23 2006-07-13 エーザイ株式会社 疾患予後モデルの作成方法、このモデルを用いた疾患予後予測方法、このモデルによる予後予測装置、ならびにそのプログラム・記憶媒体
US20040242972A1 (en) * 2003-05-28 2004-12-02 General Electric Company Method, system and computer product for prognosis of a medical disorder
US20050059024A1 (en) 2003-07-25 2005-03-17 Ambion, Inc. Methods and compositions for isolating small RNA molecules
US20050060295A1 (en) * 2003-09-12 2005-03-17 Sensory Networks, Inc. Statistical classification of high-speed network data through content inspection
CA2549971A1 (en) 2003-11-03 2005-05-12 Duke University Methods of identifying individuals at risk of perioperative bleeding, renal dysfunction or stroke
CA2554836A1 (en) 2004-02-05 2005-08-25 Medtronic, Inc. Methods and apparatus for identifying patients at risk for life threatening arrhythmias
US7759079B2 (en) * 2004-05-13 2010-07-20 Prometheus Laboratories Inc. Methods of diagnosing inflammatory bowel disease
US20060154276A1 (en) 2004-05-13 2006-07-13 Prometheus Laboratories Inc. Methods of diagnosing inflammatory bowel disease
WO2006012472A1 (en) 2004-07-21 2006-02-02 Qualyst, Inc. Apparatus, kits and methods for evaluating binding interactions, for detecting and quantifying binding molecules, and for sample preparation
AU2005314089B2 (en) * 2004-12-08 2011-03-03 Cedars-Sinai Medical Center Methods for diagnosis and treatment of Crohn's disease
US7873479B2 (en) 2005-12-01 2011-01-18 Prometheus Laboratories Inc. Methods of diagnosing inflammatory bowel disease
US20080085524A1 (en) 2006-08-15 2008-04-10 Prometheus Laboratories Inc. Methods for diagnosing irritable bowel syndrome
US20100015156A1 (en) * 2007-03-06 2010-01-21 Cedars-Sinai Medical Center Diagnosis of inflammatory bowel disease in children
US8153443B2 (en) * 2007-05-10 2012-04-10 Cedars-Sinai Medical Center Characterization of the CBir1 antigenic response for diagnosis and treatment of Crohn's disease
WO2010056682A2 (en) * 2008-11-11 2010-05-20 Prometheus Laboratories Inc. Methods for prediction of inflammatory bowel disease (ibd) using serologic markers
US9434771B2 (en) 2008-12-17 2016-09-06 The Johns Hopkins University Compositions and methods for diagnosing and treating inflammatory bowel disease and related disorders
US20120171672A1 (en) 2009-04-14 2012-07-05 Prometheus Laboratories Inc. Inflammatory bowel disease prognostics
NZ595471A (en) 2009-04-14 2014-01-31 Nestec Sa Inflammatory bowel disease prognostics
CA2766157A1 (en) 2009-06-25 2010-12-29 Hua Gong Methods for diagnosing irritable bowel syndrome
JP2013511988A (ja) 2009-11-25 2013-04-11 ネステク ソシエテ アノニム 過敏性腸症候群診断用の新規なゲノムバイオマーカー
EP2769321B1 (en) 2011-10-21 2016-06-01 Nestec S.A. Methods for improving inflammatory bowel disease diagnosis

Also Published As

Publication number Publication date
IL215619A0 (en) 2012-01-31
EP2419529B1 (en) 2015-05-20
ES2553415T3 (es) 2015-12-09
EP2960342A1 (en) 2015-12-30
CA2758531A1 (en) 2010-10-21
US9732385B2 (en) 2017-08-15
NZ595471A (en) 2014-01-31
AU2010236568A1 (en) 2011-11-03
CA2758531C (en) 2018-11-13
IL215619A (en) 2016-02-29
AU2010236568B2 (en) 2015-08-27
IL240082A0 (en) 2015-08-31
EP2419529A1 (en) 2012-02-22
NZ619527A (en) 2015-06-26
WO2010120814A1 (en) 2010-10-21
US20110045476A1 (en) 2011-02-24

Similar Documents

Publication Publication Date Title
ZA201001486B (en) Diagnosis,staging and monitoring of inflammatory bowel disease
BR112013016202A2 (pt) fluidos de perfuração tendo potencial de deformação reduzido e métodos relacionados
BRPI0718945A2 (pt) Novos esteróides apresentando solubilidade em água e resistência contra metabolismo aumentadas, e métodos para sua produção
BRPI0911998A2 (pt) métodos e kits para o tratamento de condições de desordem inflamatória intestinal
EP2997162A4 (en) Methods for diagnosing and treating inflammatory bowel disease
GB2435118C (en) Multiprocessor system and boot-up method of slave system.
BRPI0910608A2 (pt) métodos e sistemas para avaliar resultados clínicos
IL233096A0 (en) Ratio based biomarkers and methods of use thereof
EP2635295A4 (en) CONTROL AND CHARACTERIZATION OF MEMORY FUNCTIONS
BR112012003061A2 (pt) estruturas fibrosas e métodos para fabricação das mesmas
BRPI1015026A2 (pt) método e aparelho para facilitar os procedimentos de medição em operação de multiportadora.
BR112012002955A2 (pt) estruturas fibrosas e métodos de fabricação das mesmas.
BRPI0822374A2 (pt) aparelhos e métodos para avaliar uma pessoa para um sistema de sono
BRPI0821145A2 (pt) Agente terapêutico para prurido
BR112013001875A2 (pt) cueca masculina com espaço separado para o pênis
IL215619A (en) Prognosis of infectious bowel disease
IT1397197B1 (it) Veicolo battipista e relativo metodo di controllo.
BRPI0820885A2 (pt) Composições e métodos para diagnóstico precoce de gravidez
BR112012002238A2 (pt) método para executar uma função cooperativa, dispositivo para executar automaticamente uma função cooperativa com outro dispositivo, e sistema para executar automaticamente uma função cooperativa
DK2430452T3 (da) Carcinom-diagnose og behandlinger, baseret på odc1-genotype
BR112013014479A2 (pt) método melhorado e kit para determinar a gravidade e progressão da doença periodontal
EP2903629A4 (en) ASSOCIATED WITH INFLAMMATORY DARMINARY ANTIGENES
BRPI1015927A2 (pt) Kit e método para diagnosticar uma doença de tireoide e método para diagnosticar o hipotireoidismo, bem como célula e seu uso
ZA202000242B (en) Targeted defa5 antibody and assay methods for diagnosing and treating inflammatory bowel disease
EP2140261A4 (en) METHODS AND AGENTS FOR ASSESSING INFLAMMATORY ABDOMINAL INFECTION AND TARGETS FOR TREATMENT

Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: NESTEC S.A. (CH)

B25A Requested transfer of rights approved

Owner name: NESTEC S.A. (CH)

B25L Entry of change of name and/or headquarter and transfer of application, patent and certificate of addition of invention: publication cancelled

Owner name: NESTEC S.A. (CH)

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements