BRPI1014123A2 - produção de isopreno melhorada usando o caminho dxp e mva. - Google Patents
produção de isopreno melhorada usando o caminho dxp e mva.Info
- Publication number
- BRPI1014123A2 BRPI1014123A2 BRPI1014123A BRPI1014123A BRPI1014123A2 BR PI1014123 A2 BRPI1014123 A2 BR PI1014123A2 BR PI1014123 A BRPI1014123 A BR PI1014123A BR PI1014123 A BRPI1014123 A BR PI1014123A BR PI1014123 A2 BRPI1014123 A2 BR PI1014123A2
- Authority
- BR
- Brazil
- Prior art keywords
- path
- dxp
- mva
- isoprene production
- improved isoprene
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Plant Pathology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
produção de isopreno melhorada usando o caminho dxp e mva a presente invenção refere-se a métodos de produção de isopreno a partir de células cultivadas, com o uso de vários componentes do caminho dxp e caminho mva, ou componentes associados ao caminho dxp e ao caminho mva, polipeptídeos redox de interação por agrupamento ferro-enxofre e isopreno sintase. a invenção também fornece composições que incluem estas células cultivadas.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18794109P | 2009-06-17 | 2009-06-17 | |
| US18793009P | 2009-06-17 | 2009-06-17 | |
| US31498510P | 2010-03-17 | 2010-03-17 | |
| US31497910P | 2010-03-17 | 2010-03-17 | |
| PCT/US2010/038904 WO2010148150A1 (en) | 2009-06-17 | 2010-06-16 | Improved isoprene production using the dxp and mva pathway |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI1014123A2 true BRPI1014123A2 (pt) | 2019-07-02 |
Family
ID=43356749
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI1014123A BRPI1014123A2 (pt) | 2009-06-17 | 2010-06-16 | produção de isopreno melhorada usando o caminho dxp e mva. |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US8507235B2 (pt) |
| EP (1) | EP2443244A4 (pt) |
| CN (1) | CN102753697A (pt) |
| AR (1) | AR077115A1 (pt) |
| BR (1) | BRPI1014123A2 (pt) |
| CA (1) | CA2765805A1 (pt) |
| MY (1) | MY158160A (pt) |
| SG (2) | SG10201403297UA (pt) |
| TW (2) | TWI427149B (pt) |
| WO (1) | WO2010148150A1 (pt) |
Families Citing this family (62)
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|---|---|---|---|---|
| JP2011518564A (ja) | 2008-04-23 | 2011-06-30 | ダニスコ・ユーエス・インク | 改良された微生物によるイソプレン産出用のイソプレンシンターゼ変異体 |
| US20100184178A1 (en) * | 2008-09-15 | 2010-07-22 | Zachary Quinn Beck | Increased isoprene production using mevalonate kinase and isoprene synthase |
| WO2010031068A1 (en) * | 2008-09-15 | 2010-03-18 | Danisco Us Inc. | Reduction of carbon dioxide emission during isoprene production by fermentation |
| WO2010031062A1 (en) | 2008-09-15 | 2010-03-18 | Danisco Us Inc. | Increased isoprene production using the archaeal lower mevalonate pathway |
| US8647642B2 (en) | 2008-09-18 | 2014-02-11 | Aviex Technologies, Llc | Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment |
| CA2759700A1 (en) | 2009-04-23 | 2010-10-28 | Danisco Us Inc. | Three-dimensional structure of isoprene synthase and its use thereof for generating variants |
| TWI427149B (zh) | 2009-06-17 | 2014-02-21 | Danisco Us Inc | 使用dxp及mva途徑之改良之異戊二烯製造 |
| US20110039323A1 (en) * | 2009-08-14 | 2011-02-17 | Eric Lawrence Singsaas | Isoprene Production |
| BR112012014736B1 (pt) * | 2009-12-18 | 2018-09-18 | Danisco Us Inc | método para purificação de isopreno a partir de um efluente gasoso do fermentador e composição |
| JP5855576B2 (ja) * | 2009-12-22 | 2016-02-09 | ダニスコ・ユーエス・インク | イソプレンガスの生成量を増大させるための膜バイオリアクター |
| WO2011160081A1 (en) | 2010-06-17 | 2011-12-22 | Danisco Us Inc. | Fuel compositions comprising isoprene derivatives |
| WO2012019169A1 (en) | 2010-08-06 | 2012-02-09 | Danisco Us Inc. | Production of isoprene under neutral ph conditions |
| BR112013010551A8 (pt) | 2010-10-27 | 2018-07-03 | Danisco Us Inc | variantes de isopreno sintase para produção aprimorada de isopreno |
| CN103476926A (zh) | 2010-12-22 | 2013-12-25 | 丹尼斯科美国公司 | 使用两种类型的ispg酶改善异戊二烯产量的组合物和方法 |
| US8691541B2 (en) | 2010-12-22 | 2014-04-08 | Danisco Us Inc. | Biological production of pentose sugars using recombinant cells |
| WO2012135591A2 (en) * | 2011-03-30 | 2012-10-04 | Amyris, Inc. | Microbial isoprenoid production using a heterologous dxp pathway |
| BR112013027555A2 (pt) | 2011-04-29 | 2021-08-10 | Danisco Us Inc. | células recombinantes capazes de maior produção de isopreno, mevalonato e isoprenoides e método para produzir isopreno, mevalonato e isoprenoides |
| EP2702139A1 (en) | 2011-04-29 | 2014-03-05 | Danisco US Inc. | Production of mevalonate, isoprene, and isoprenoids using genes encoding polypeptides having thiolase, hmg-coa synthase and hmg-coa reductase enzymatic activities |
| SG2014007991A (en) | 2011-08-04 | 2014-03-28 | Danisco Us Inc | Production of isoprene, isoprenoid precursors, and isoprenoids using acetoacetyl-coa synthase |
| WO2013022799A1 (en) | 2011-08-05 | 2013-02-14 | Danisco Us Inc. | PRODUCTION OF ISOPRENOIDS UNDER NEUTRAL pH CONDITIONS |
| PL222067B1 (pl) * | 2011-08-11 | 2016-06-30 | Inst Biotechnologii I Antybiotyków | Kaseta ekspresyjna, zastosowanie kasety ekspresyjnej, wektor ekspresyjny, komórka prokariotycznego gospodarza zawierająca wektor ekspresyjny, szczep bakteryjny oraz sposób wytwarzania polipeptydu |
| JP6420147B2 (ja) | 2011-10-07 | 2018-11-07 | ダニスコ・ユーエス・インク | メバロン酸、イソプレノイド前駆体、及びイソプレンの産生におけるホスホケトラーゼの使用 |
| CA2853125A1 (en) | 2011-10-27 | 2013-05-02 | The Goodyear Tire & Rubber Company | Isoprene synthase variants with improved solubility for production of isoprene |
| WO2013096863A1 (en) * | 2011-12-23 | 2013-06-27 | The Regents Of The University Of California | Constructs and methods for improved isoprene biosynthesis |
| WO2013096917A1 (en) | 2011-12-23 | 2013-06-27 | Danisco Us Inc. | Production of isoprene under reduced oxygen inlet levels |
| JP2015510392A (ja) | 2011-12-23 | 2015-04-09 | ダニスコ・ユーエス・インク | 低減したispa活性を有する宿主細胞を用いるイソプレン産生増強法 |
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| US9163263B2 (en) | 2012-05-02 | 2015-10-20 | The Goodyear Tire & Rubber Company | Identification of isoprene synthase variants with improved properties for the production of isoprene |
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| DK2898053T3 (da) | 2012-09-20 | 2021-11-22 | Danisco Us Inc | Mikrotiterplader til styret frigivelse af kulturbestanddele til cellekulturer |
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| WO2016015021A1 (en) | 2014-07-24 | 2016-01-28 | The Regents Of The University Of California | Oxidative starch degradation by a new family of pmos |
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| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| KR102656420B1 (ko) | 2017-01-26 | 2024-04-09 | 마누스 바이오, 인크. | 터페노이드 생성물의 미생물 생산을 위한 대사 조작 |
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-
2010
- 2010-06-15 TW TW99119621A patent/TWI427149B/zh not_active IP Right Cessation
- 2010-06-15 TW TW102141532A patent/TW201412988A/zh unknown
- 2010-06-16 SG SG10201403297UA patent/SG10201403297UA/en unknown
- 2010-06-16 MY MYPI2011006126A patent/MY158160A/en unknown
- 2010-06-16 AR ARP100102132 patent/AR077115A1/es unknown
- 2010-06-16 BR BRPI1014123A patent/BRPI1014123A2/pt not_active IP Right Cessation
- 2010-06-16 SG SG2011094562A patent/SG176936A1/en unknown
- 2010-06-16 US US12/817,134 patent/US8507235B2/en not_active Expired - Fee Related
- 2010-06-16 EP EP10790161.3A patent/EP2443244A4/en not_active Withdrawn
- 2010-06-16 CA CA2765805A patent/CA2765805A1/en not_active Abandoned
- 2010-06-16 CN CN2010800359758A patent/CN102753697A/zh active Pending
- 2010-06-16 WO PCT/US2010/038904 patent/WO2010148150A1/en not_active Ceased
-
2013
- 2013-07-11 US US13/940,092 patent/US20140162337A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AR077115A1 (es) | 2011-08-03 |
| SG176936A1 (en) | 2012-02-28 |
| TW201412988A (zh) | 2014-04-01 |
| TWI427149B (zh) | 2014-02-21 |
| CA2765805A1 (en) | 2010-12-23 |
| WO2010148150A1 (en) | 2010-12-23 |
| SG10201403297UA (en) | 2014-10-30 |
| EP2443244A1 (en) | 2012-04-25 |
| CN102753697A (zh) | 2012-10-24 |
| EP2443244A4 (en) | 2014-11-26 |
| US20110014672A1 (en) | 2011-01-20 |
| MY158160A (en) | 2016-09-15 |
| US8507235B2 (en) | 2013-08-13 |
| TW201111512A (en) | 2011-04-01 |
| US20140162337A1 (en) | 2014-06-12 |
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