CA1029719A - Preparation of a-6-deoxy-5-hydroxytetracycline - Google Patents

Preparation of a-6-deoxy-5-hydroxytetracycline

Info

Publication number: CA1029719A
Authority: CA; Canada
Prior art keywords: hydroxytetracycline; deoxy; preparation
Prior art date: 1974-05-28
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA224,909A

Other languages

English (en)

French (fr)

Other versions

CA224909S (en

Inventor

Charles J.V. Scanio

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pfizer Ltd

Original Assignee

Pfizer Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-05-28

Filing date

1975-04-17

Publication date

1978-04-18

1975-04-17 Application filed by Pfizer Ltd filed Critical Pfizer Ltd

1978-04-18 Application granted granted Critical

1978-04-18 Publication of CA1029719A publication Critical patent/CA1029719A/en

Status Expired legal-status Critical Current

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
- C07C237/26—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton of a ring being part of a condensed ring system formed by at least four rings, e.g. tetracycline
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2231/00—Catalytic reactions performed with catalysts classified in B01J31/00
- B01J2231/60—Reduction reactions, e.g. hydrogenation
- B01J2231/64—Reductions in general of organic substrates, e.g. hydride reductions or hydrogenations
- B01J2231/641—Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes
- B01J2231/645—Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes of C=C or C-C triple bonds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/40—Ortho- or ortho- and peri-condensed systems containing four condensed rings
- C07C2603/42—Ortho- or ortho- and peri-condensed systems containing four condensed rings containing only six-membered rings
- C07C2603/44—Naphthacenes; Hydrogenated naphthacenes
- C07C2603/46—1,4,4a,5,5a,6,11,12a- Octahydronaphthacenes, e.g. tetracyclines

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Saccharide Compounds (AREA)

CA224,909A 1974-05-28 1975-04-17 Preparation of a-6-deoxy-5-hydroxytetracycline Expired CA1029719A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US473791A US3907890A (en)	1974-05-28	1974-05-28	Preparation of alpha-6-deoxy-5-hydroxytetracycline

Publications (1)

Publication Number	Publication Date
CA1029719A true CA1029719A (en)	1978-04-18

Family

ID=23880982

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA224,909A Expired CA1029719A (en)	1974-05-28	1975-04-17	Preparation of a-6-deoxy-5-hydroxytetracycline

Country Status (33)

Country	Link
US (1)	US3907890A (cs)
JP (1)	JPS585185B2 (cs)
AR (1)	AR204864A1 (cs)
AT (1)	AT338421B (cs)
BE (1)	BE829344A (cs)
BG (1)	BG29427A3 (cs)
CA (1)	CA1029719A (cs)
CH (1)	CH602592A5 (cs)
CS (1)	CS176141B2 (cs)
DE (1)	DE2520546A1 (cs)
DK (1)	DK145877C (cs)
EG (1)	EG11666A (cs)
ES (1)	ES437047A1 (cs)
FI (1)	FI58910C (cs)
FR (1)	FR2272978B1 (cs)
GB (1)	GB1478587A (cs)
HK (1)	HK28579A (cs)
HU (1)	HU169913B (cs)
IE (1)	IE41554B1 (cs)
IL (1)	IL47118A (cs)
IN (1)	IN141263B (cs)
KE (1)	KE2935A (cs)
LU (1)	LU72566A1 (cs)
MY (1)	MY7900244A (cs)
NL (1)	NL180310C (cs)
NO (1)	NO146199C (cs)
PH (1)	PH10678A (cs)
PL (1)	PL96623B1 (cs)
RO (1)	RO72528A (cs)
SE (1)	SE421612B (cs)
SU (1)	SU578865A3 (cs)
YU (1)	YU39319B (cs)
ZA (1)	ZA752639B (cs)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3962131A (en) *	1975-01-28	1976-06-08	Pfizer Inc.	Rhodium containing catalyst and use thereof in preparation of 6-deoxy-5-oxytetracycline
US4218340A (en) *	1975-11-19	1980-08-19	Eastman Kodak Company	Nickel and cobalt containing carbonylation catalyst compositions for the production of carboxylic acids and their esters
US4374752A (en) *	1981-06-30	1983-02-22	Union Carbide Corporation	Catalyst and process for the conversion of methanol to acetaldehyde
US4500458A (en) *	1982-01-19	1985-02-19	Plurichemie Anstalt	Process for the preparation of α-6-deoxytetracyclines
DK386784A (da) *	1983-08-17	1985-02-18	Hovione Int Ltd	Fremgangsmaade til fremstilling af alfa-6-desoxy-tetracykliner
JPS6425298A (en) *	1987-07-21	1989-01-27	Yazaki Corp	Gas leakage warning device
US4973719A (en) *	1988-10-28	1990-11-27	Ranbaxy Laboratories Limited	Process for the production of alpha-6-deoxytetracyclines
US4987242A (en) *	1988-10-28	1991-01-22	Jagmohan Khanna	Hydrogenation catalyst useful in the production of alpha-6-deoxytetracyclines
US4902447A (en) *	1988-10-28	1990-02-20	Ranbaxy Laboratories Limited	Process for the production of alpha-6-deoxytetracyclines and hydrogenation catalyst useful therein
US5049683A (en) *	1989-01-04	1991-09-17	Houba, Inc.	Process for the production of alpha-6-deoxytetracyclines
DE391005T1 (de) *	1989-04-03	1991-04-11	Ranbaxy Laboratories, Ltd., New Delhi	Verfahren zur herstellung von alpha-6-deoxytetracyclinen.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR1430859A (cs) *	1960-05-23	1966-05-25
GB1182353A (en) *	1966-02-07	1970-02-25	Montedison Spa	Cobalt Hydrocarbonyls
US3444198A (en) *	1967-02-13	1969-05-13	Pfizer & Co C	Process for producing alpha-6-deoxytetracyclines
US3692864A (en) *	1970-09-30	1972-09-19	Texaco Inc	Hydrogenation process utilizing homogeneous metal catalysts
US3717585A (en) *	1971-01-08	1973-02-20	Phillips Petroleum Co	Promoted trihydrocarbylphosphine modified carbonyl cobalt catalyst system

1974
- 1974-05-28 US US473791A patent/US3907890A/en not_active Expired - Lifetime
1975
- 1975-01-01 AR AR258926A patent/AR204864A1/es active
- 1975-03-19 IE IE591/75A patent/IE41554B1/en unknown
- 1975-04-10 SE SE7504140A patent/SE421612B/xx not_active IP Right Cessation
- 1975-04-17 NO NO751389A patent/NO146199C/no unknown
- 1975-04-17 CA CA224,909A patent/CA1029719A/en not_active Expired
- 1975-04-18 IL IL47118A patent/IL47118A/xx unknown
- 1975-04-18 IN IN775/CAL/1975A patent/IN141263B/en unknown
- 1975-04-23 ZA ZA00752639A patent/ZA752639B/xx unknown
- 1975-04-23 PH PH17008A patent/PH10678A/en unknown
- 1975-04-26 ES ES437047A patent/ES437047A1/es not_active Expired
- 1975-05-06 DE DE19752520546 patent/DE2520546A1/de active Pending
- 1975-05-12 AT AT359375A patent/AT338421B/de not_active IP Right Cessation
- 1975-05-15 FI FI751437A patent/FI58910C/fi not_active IP Right Cessation
- 1975-05-20 GB GB21672/75A patent/GB1478587A/en not_active Expired
- 1975-05-21 NL NLAANVRAGE7505943,A patent/NL180310C/xx not_active IP Right Cessation
- 1975-05-22 SU SU7502139303A patent/SU578865A3/ru active
- 1975-05-22 BE BE1006680A patent/BE829344A/xx not_active IP Right Cessation
- 1975-05-22 JP JP50061419A patent/JPS585185B2/ja not_active Expired
- 1975-05-22 CH CH658575A patent/CH602592A5/xx not_active IP Right Cessation
- 1975-05-22 RO RO7582307A patent/RO72528A/ro unknown
- 1975-05-22 HU HUPI472A patent/HU169913B/hu not_active IP Right Cessation
- 1975-05-22 DK DK225075A patent/DK145877C/da active
- 1975-05-23 YU YU1328/75A patent/YU39319B/xx unknown
- 1975-05-23 CS CS3638A patent/CS176141B2/cs unknown
- 1975-05-23 LU LU72566A patent/LU72566A1/xx unknown
- 1975-05-23 FR FR7516196A patent/FR2272978B1/fr not_active Expired
- 1975-05-26 BG BG030090A patent/BG29427A3/xx unknown
- 1975-05-27 EG EG314/75A patent/EG11666A/xx active
- 1975-05-28 PL PL1975180782A patent/PL96623B1/pl unknown
1979
- 1979-03-16 KE KE2935A patent/KE2935A/xx unknown
- 1979-05-03 HK HK285/79A patent/HK28579A/xx unknown
- 1979-12-30 MY MY244/79A patent/MY7900244A/xx unknown

Also Published As

Publication number	Publication date
FR2272978A1 (cs)	1975-12-26
SE421612B (sv)	1982-01-18
DE2520546A1 (de)	1975-12-04
SE7504140L (sv)	1975-12-01
CH602592A5 (cs)	1978-07-31
FI58910B (fi)	1981-01-30
ATA359375A (de)	1976-12-15
JPS50160261A (cs)	1975-12-25
LU72566A1 (cs)	1976-03-17
IN141263B (cs)	1977-02-05
IL47118A (en)	1978-01-31
ES437047A1 (es)	1977-01-16
DK225075A (da)	1975-11-29
EG11666A (en)	1978-03-29
FR2272978B1 (cs)	1978-06-09
HK28579A (en)	1979-05-11
AR204864A1 (es)	1976-03-05
IL47118A0 (en)	1975-06-25
GB1478587A (en)	1977-07-06
ZA752639B (en)	1976-04-28
US3907890A (en)	1975-09-23
PH10678A (en)	1977-08-05
NL7505943A (nl)	1975-12-02
DK145877C (da)	1983-09-12
BE829344A (fr)	1975-11-24
AT338421B (de)	1977-08-25
HU169913B (cs)	1977-02-28
YU39319B (en)	1984-10-31
NO751389L (cs)	1975-12-01
JPS585185B2 (ja)	1983-01-29
SU578865A3 (ru)	1977-10-30
PL96623B1 (pl)	1978-01-31
MY7900244A (en)	1979-12-31
DK145877B (da)	1983-03-28
FI751437A7 (cs)	1975-11-29
BG29427A3 (bg)	1980-11-14
NO146199C (no)	1982-08-18
FI58910C (fi)	1981-05-11
KE2935A (en)	1979-03-30
IE41554B1 (en)	1980-01-30
YU132875A (en)	1982-05-31
CS176141B2 (cs)	1977-06-30
NL180310B (nl)	1986-09-01
NO146199B (no)	1982-05-10
RO72528A (ro)	1981-11-04
NL180310C (nl)	1987-02-02
IE41554L (en)	1975-11-28

Publication	Publication Date	Title
AU497036B2 (en)	1978-11-23	Preparation of liposomes
CA1031346A (en)	1978-05-16	Preparation of bipyridilium compounds
JPS5384944A (en)	1978-07-26	Preparation of betaacycloohomocitral
CA1019328A (en)	1977-10-18	Series of 5-aryl-2-furamidines
ZA752639B (en)	1976-04-28	Preparation of alpha-6-deoxy-5-hydroxy-tetracycline
CA1022566A (en)	1977-12-13	Preparation of hydrazodicarbonamide
AU476488B2 (en)	1976-09-23	Preparation of 6-deoxytetracyclines
AU501035B2 (en)	1979-06-07	Preparation of dibenzofuran
CA1026754A (en)	1978-02-21	Preparation of hexamethyleneimine
ZA75471B (en)	1976-01-28	Preparation of dithiodianilines
AU494144B2 (en)	1976-05-06	Application of tie-cords
AU484570B2 (en)	1976-08-12	Preparation of substituted diphenylnitroalkanes
AU7835075A (en)	1976-08-19	Preparation of cis-vincamine
JPS51125221A (en)	1976-11-01	Preparation of ethynylbenzenes
AU485538B2 (en)	1976-10-28	Preparation ofa-6-deoxy-5-hydroxytetracycline
AU487379B2 (en)	1976-01-15	Preparation of monoholacyl halides
AU499330B2 (en)	1979-04-12	Preparation of reprognaphic sheets
SU566910A1 (ru)	1977-07-30	Соединение элементов
CA1025864A (en)	1978-02-07	Preparation of 2-amino-4-hydroxypyrimidines
AU473301B2 (en)	1976-06-17	3-substituted-iodo-alkenyl compounds and preparation thereof
AU488815B2 (en)	1976-01-22	Polymerisatin of cyclooctene
AU485202B2 (en)	1976-11-25	Process forthe preparation of dioldiones
AU486493B2 (en)	1977-01-06	Process forthe preparation of acetozybutanal
AU484102B2 (en)	1976-06-24	Process forthe preparation of choleragen
CA1030557A (en)	1978-05-02	Preparation of 5-methyl-2-nitrophenol