CA1043791A - Imidazolinylaminoquinoxalines - Google Patents

Imidazolinylaminoquinoxalines

Info

Publication number
CA1043791A
CA1043791A CA234,270A CA234270A CA1043791A CA 1043791 A CA1043791 A CA 1043791A CA 234270 A CA234270 A CA 234270A CA 1043791 A CA1043791 A CA 1043791A
Authority
CA
Canada
Prior art keywords
formula
compound
isothiocyanate
group
quinoxaline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA234,270A
Other languages
English (en)
Other versions
CA234270S (en
Inventor
Michael B. Thomas
Michael T. Williams
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp SRL
Original Assignee
Pfizer Corp SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp SRL filed Critical Pfizer Corp SRL
Application granted granted Critical
Publication of CA1043791A publication Critical patent/CA1043791A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CA234,270A 1974-09-06 1975-08-27 Imidazolinylaminoquinoxalines Expired CA1043791A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3914374A GB1463520A (en) 1974-09-06 1974-09-06 Process for the production of imidazolines

Publications (1)

Publication Number Publication Date
CA1043791A true CA1043791A (fr) 1978-12-05

Family

ID=10407882

Family Applications (1)

Application Number Title Priority Date Filing Date
CA234,270A Expired CA1043791A (fr) 1974-09-06 1975-08-27 Imidazolinylaminoquinoxalines

Country Status (12)

Country Link
JP (1) JPS51149291A (fr)
BE (1) BE833135A (fr)
CA (1) CA1043791A (fr)
DE (1) DE2538620A1 (fr)
DK (1) DK398775A (fr)
ES (1) ES440760A1 (fr)
FI (1) FI752487A7 (fr)
FR (1) FR2283899A1 (fr)
GB (1) GB1463520A (fr)
LU (1) LU73327A1 (fr)
NL (1) NL7510473A (fr)
SE (1) SE7509271L (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5077292A (en) * 1989-10-12 1991-12-31 Allergan, Inc. (2-imidazolin-2-ylamino) tetrahydroquinoxalines and methods for using same
US5112822A (en) * 1989-10-12 1992-05-12 Allergan, Inc. (2-imidazolin-2-ylamino) quinoxaline derivatives and methods for using same
US5326763A (en) * 1989-10-12 1994-07-05 Allergan, Inc. Methods for using (2-imidazolin-2-ylamino) quinoxaline derivatives
US5204347A (en) * 1989-10-12 1993-04-20 Allergan, Inc. Methods for using (2-imidazolin-2-ylamino) tetrahydroquinoxalines
US5198442A (en) * 1989-10-12 1993-03-30 Allergan, Inc. (2-imidazolin-2-ylamino) quinoxaline derivatives and methods for using same
US5021416A (en) * 1989-10-31 1991-06-04 Allergan, Inc. Method for using (2-imidazolin-2-ylamino) quinoxalines to reduce or maintain intraocular pressure
US5237072A (en) * 1990-02-06 1993-08-17 Allergan, Inc. Method for producing amino-2-imidazoline derivatives
US5130441A (en) * 1990-02-06 1992-07-14 Allergan, Inc. Method for producing amino-2-imidazoline derivatives
US6323204B1 (en) 1993-10-13 2001-11-27 Allergan Methods for using (2-imidazolin-2-ylamino) quinoxaline derivatives
JP3683908B2 (ja) * 1993-10-13 2005-08-17 アラーガン、インコーポレイテッド （２−イミダゾリン−２−イルアミノ）キノキサリン誘導体の使用方法
CA2505836C (fr) 2004-05-06 2013-08-27 Alcon Inc. Formulations topiques de tartrate de brimonidine exemptes de dioxyde de chlore
RU2285003C1 (ru) * 2005-04-29 2006-10-10 Федеральное государственное унитарное предприятие "Центр по химии лекарственных средств" (ФГУП ЦХЛС-ВНИХФИ) Способ получения 5-бром-6-[(2-имидазолин-2-ил)амино]хиноксалина l-тартрата
WO2015097600A2 (fr) 2013-12-24 2015-07-02 Sentiss Pharma Private Limited Solution ophthalmique topique de tartrate de brimonidine
JP6339364B2 (ja) * 2013-12-27 2018-06-06 カズマパートナーズ株式会社 無定形ブリモニジン酒石酸塩及びその製造方法
JP6270603B2 (ja) * 2014-04-14 2018-01-31 カズマパートナーズ株式会社 ブリモニジン酒石酸塩の新規多形及びその製造方法
US20230218611A1 (en) 2020-04-29 2023-07-13 Sentiss Pharma Private Limited Ophthalmic compositions comprising a combination of brinzolamide and brimonidine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE795970A (fr) * 1972-02-29 1973-08-27 Pfizer Nouveaux derives de quinoleine, quinoxaline et quinazoline er composition pharmaceutiques les contenant

Also Published As

Publication number Publication date
NL7510473A (nl) 1976-03-09
DK398775A (da) 1976-03-07
LU73327A1 (fr) 1977-05-11
ES440760A1 (es) 1977-04-01
AU8430575A (en) 1977-03-03
GB1463520A (en) 1977-02-02
FI752487A7 (fr) 1976-03-07
FR2283899A1 (fr) 1976-04-02
DE2538620A1 (de) 1976-03-18
BE833135A (fr) 1976-03-05
JPS51149291A (en) 1976-12-22
SE7509271L (sv) 1975-12-29

Similar Documents

Publication Publication Date Title
Blicke et al. Reactions of 1, 3-Dimethyl-5, 6-diaminouracil
AU631860B2 (en) An improved process for the preparation of substituted isoflavone derivatives
JPH0329791B2 (fr)
US2581889A (en) Method of preparing pyrimidopyrazines
US3049544A (en) Method for the preparation of
DE2538620A1 (de) Verfahren zur herstellung von chinoxalin- und chinazolinderivaten
US3847934A (en) 7-(imidazolinyl-(2)-amino)-indazoles
US2587262A (en) Chs chzghjoh
Maggiolo The Reaction of Thiocyanogen with Nitrogen Heterocycles; Pyridines, Pyrmidines and Quinolines1
US2701252A (en) Isoindolenine compounds
CS202069B2 (en) Method of preparing 2-/4-substituted piperazine-1-yl/-4-amino-6,7-dimethoxyquinazolines
US3494921A (en) 1,4-disubstituted pyridazino(4,5-d) pyridazines
SU999967A3 (ru) Способ получени 6-N-замещенных 6-амино-3-пиридазинилгидразинов или их солей
US3923804A (en) Nitro-pyrimidines
JP2726653B2 (ja) ジアミノピリミジン誘導体
US2503899A (en) Diacridyl diamine derivatives
SE415970B (sv) Nytt forfarande for framstellning av n-(trans-4-hydroxicyklohexyl)-(2-amino-3,5-dibrom-bensyl)-amin
SU415876A3 (ru) Способ получения производных бензимидазола
JPH08505410A (ja) ２−アルコキシ−４−ヒドラジノピリミジン化合物及び５−アルコキシ−１，２，４−トリアゾロ［４，３−ｃピリミジン−３（２Ｈ）−チオン化合物の製造におけるそれらの利用
US2496364A (en) 3 - sulfanilamido-benzotriazines-1,2,4 and method for their preparation
NL8003153A (nl) Werkwijze voor het bereiden van n-(2-amino-3,5-dibroombenzyl)-n-methylcyclohexylamine ("bromhexin").
US2886576A (en) 3-(3-nitroanilino)phthalide
US3673178A (en) Process for preparing 2-{8 2-(arylamino)-vinyl{9 -1-(lower alkyl)-3-h-indolium salt dyes
US2579320A (en) Process for the preparation of 3, 4, 7-trihaloquinolines
US3347864A (en) Production of aminoquinolines