CA1118155A - Implant fait d'un substrat de carbone biocompatible enrobe de collagene - Google Patents
Implant fait d'un substrat de carbone biocompatible enrobe de collageneInfo
- Publication number
- CA1118155A CA1118155A CA000320243A CA320243A CA1118155A CA 1118155 A CA1118155 A CA 1118155A CA 000320243 A CA000320243 A CA 000320243A CA 320243 A CA320243 A CA 320243A CA 1118155 A CA1118155 A CA 1118155A
- Authority
- CA
- Canada
- Prior art keywords
- implant device
- substrate
- carbon
- collagen
- filaments
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 title claims abstract description 29
- 239000000758 substrate Substances 0.000 title claims abstract description 24
- 239000007943 implant Substances 0.000 title claims abstract description 20
- 229910052799 carbon Inorganic materials 0.000 title claims abstract description 19
- 102000008186 Collagen Human genes 0.000 title claims abstract description 14
- 108010035532 Collagen Proteins 0.000 title claims abstract description 14
- 229920001436 collagen Polymers 0.000 title claims abstract description 14
- 229910021397 glassy carbon Inorganic materials 0.000 claims description 5
- 229910002804 graphite Inorganic materials 0.000 claims description 5
- 239000010439 graphite Substances 0.000 claims description 5
- 239000002296 pyrolytic carbon Substances 0.000 claims description 5
- 239000011230 binding agent Substances 0.000 claims description 3
- 239000000463 material Substances 0.000 claims 3
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 238000009740 moulding (composite fabrication) Methods 0.000 claims 1
- 210000004204 blood vessel Anatomy 0.000 abstract description 4
- 238000007789 sealing Methods 0.000 abstract description 2
- 210000001519 tissue Anatomy 0.000 description 8
- 210000000056 organ Anatomy 0.000 description 5
- 239000008280 blood Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 102000004169 proteins and genes Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 210000003491 skin Anatomy 0.000 description 3
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 description 2
- PMMYEEVYMWASQN-DMTCNVIQSA-N Hydroxyproline Chemical compound O[C@H]1CN[C@H](C(O)=O)C1 PMMYEEVYMWASQN-DMTCNVIQSA-N 0.000 description 2
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 description 2
- 239000002473 artificial blood Substances 0.000 description 2
- CVSVTCORWBXHQV-UHFFFAOYSA-N creatine Chemical compound NC(=[NH2+])N(C)CC([O-])=O CVSVTCORWBXHQV-UHFFFAOYSA-N 0.000 description 2
- 238000000502 dialysis Methods 0.000 description 2
- PMMYEEVYMWASQN-UHFFFAOYSA-N dl-hydroxyproline Natural products OC1C[NH2+]C(C([O-])=O)C1 PMMYEEVYMWASQN-UHFFFAOYSA-N 0.000 description 2
- 229910052739 hydrogen Inorganic materials 0.000 description 2
- 239000001257 hydrogen Substances 0.000 description 2
- 229960002591 hydroxyproline Drugs 0.000 description 2
- FGMPLJWBKKVCDB-UHFFFAOYSA-N trans-L-hydroxy-proline Natural products ON1CCCC1C(O)=O FGMPLJWBKKVCDB-UHFFFAOYSA-N 0.000 description 2
- 230000002792 vascular Effects 0.000 description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 239000004471 Glycine Substances 0.000 description 1
- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 description 1
- 208000001647 Renal Insufficiency Diseases 0.000 description 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 210000000845 cartilage Anatomy 0.000 description 1
- 210000001072 colon Anatomy 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 229960003624 creatine Drugs 0.000 description 1
- 239000006046 creatine Substances 0.000 description 1
- 210000004207 dermis Anatomy 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 125000003630 glycyl group Chemical group [H]N([H])C([H])([H])C(*)=O 0.000 description 1
- BHEPBYXIRTUNPN-UHFFFAOYSA-N hydridophosphorus(.) (triplet) Chemical compound [PH] BHEPBYXIRTUNPN-UHFFFAOYSA-N 0.000 description 1
- 210000003405 ileum Anatomy 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 201000006370 kidney failure Diseases 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000005445 natural material Substances 0.000 description 1
- 210000004197 pelvis Anatomy 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 125000001500 prolyl group Chemical group [H]N1C([H])(C(=O)[*])C([H])([H])C([H])([H])C1([H])[H] 0.000 description 1
- 210000002435 tendon Anatomy 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 125000003508 trans-4-hydroxy-L-proline group Chemical group 0.000 description 1
- 210000000626 ureter Anatomy 0.000 description 1
- 210000003708 urethra Anatomy 0.000 description 1
- NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/062—Apparatus for the production of blood vessels made from natural tissue or with layers of living cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L27/443—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with carbon fillers
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Composite Materials (AREA)
- Materials Engineering (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87224178A | 1978-01-25 | 1978-01-25 | |
| US872,241 | 1978-01-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1118155A true CA1118155A (fr) | 1982-02-16 |
Family
ID=25359139
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000320243A Expired CA1118155A (fr) | 1978-01-25 | 1979-01-25 | Implant fait d'un substrat de carbone biocompatible enrobe de collagene |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JPS54119798A (fr) |
| BR (1) | BR7900377A (fr) |
| CA (1) | CA1118155A (fr) |
| DE (1) | DE2853614A1 (fr) |
| FR (1) | FR2415456A1 (fr) |
| GB (1) | GB2014475B (fr) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57134154A (en) * | 1981-02-12 | 1982-08-19 | Otani Sugirou | Carbonacious artificial filler and prosthetic material and production thereof |
| FR2510394A1 (fr) * | 1981-07-30 | 1983-02-04 | Ceraver | Ligament ou tendon prothetique, et procedes de fabrication de ceux-ci |
| FR2511249A1 (fr) * | 1981-08-14 | 1983-02-18 | Bentley Lab | Raccord a implanter dans le corps |
| JPH0669741B2 (ja) * | 1985-01-16 | 1994-09-07 | 東レ株式会社 | シ−ト状物 |
| US4699141A (en) * | 1986-01-16 | 1987-10-13 | Rhode Island Hospital | Neovascularization |
| CA1340581C (fr) * | 1986-11-20 | 1999-06-08 | Joseph P. Vacanti | Neomorphogenese chimerique d'organes par implatation cellulaire controlee, utilisant des matrices artificielles |
| US5804178A (en) * | 1986-11-20 | 1998-09-08 | Massachusetts Institute Of Technology | Implantation of cell-matrix structure adjacent mesentery, omentum or peritoneum tissue |
| US6309635B1 (en) | 1986-11-20 | 2001-10-30 | Children's Medical Center Corp. | Seeding parenchymal cells into compression resistant porous scaffold after vascularizing in vivo |
| JP2799596B2 (ja) * | 1989-08-10 | 1998-09-17 | 株式会社ジェイ・エム・エス | 生体埋植用具およびその製造法 |
| US5618531A (en) | 1990-10-19 | 1997-04-08 | New York University | Method for increasing the viability of cells which are administered to the brain or spinal cord |
| US5716404A (en) | 1994-12-16 | 1998-02-10 | Massachusetts Institute Of Technology | Breast tissue engineering |
| US6123727A (en) | 1995-05-01 | 2000-09-26 | Massachusetts Institute Of Technology | Tissue engineered tendons and ligaments |
| US5855610A (en) | 1995-05-19 | 1999-01-05 | Children's Medical Center Corporation | Engineering of strong, pliable tissues |
| US6129761A (en) | 1995-06-07 | 2000-10-10 | Reprogenesis, Inc. | Injectable hydrogel compositions |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1185332B (de) * | 1961-03-01 | 1965-01-14 | Ethicon Inc | Chirurgische Prothese |
| DE1494939B2 (de) * | 1963-06-11 | 1972-03-02 | Buddecke, Eckhart, Prof Dr , 4400 Munster | Implantationsmatenal fur Prothesen zum Ersatz von Arterien und anderen Korper safte enthaltenden Bahnen und Hohlorganen und Verfahren zu dessen Herstellung |
| CH472219A (de) * | 1963-06-15 | 1969-05-15 | Spofa Vereinigte Pharma Werke | Hochporöse Kollagen-Gewebe-Blutgefässprothese und Verfahren zur Herstellung derselben |
| GB1165698A (en) * | 1965-11-05 | 1969-10-01 | Guinness De Laszlo M A P Henry | Improvements in or relating to Prostheses |
| US3479670A (en) * | 1966-10-19 | 1969-11-25 | Ethicon Inc | Tubular prosthetic implant having helical thermoplastic wrapping therearound |
| AU4922069A (en) * | 1969-01-17 | 1970-07-23 | Carlton Sports Company Limited | Improvements in or relating to artificial bones joints andother parts for use inthe human body |
| DE2017330A1 (en) * | 1970-04-10 | 1971-12-09 | BIO-CAL Instrument GmbH, 8032 Gräfelfing | Blood vessel connector - for artificial kidneys or lungs |
| CS148134B1 (fr) * | 1970-11-20 | 1973-02-22 | ||
| SE393290B (sv) * | 1971-05-20 | 1977-05-09 | Vitek Inc | Materialkomposition till anvendning for implantation in vivo, vilken komposition innehaller en fibros, poros struktur samt forfarande for framstellning av en sadan komposition |
-
1978
- 1978-12-12 DE DE19782853614 patent/DE2853614A1/de not_active Withdrawn
-
1979
- 1979-01-22 BR BR7900377A patent/BR7900377A/pt unknown
- 1979-01-24 FR FR7901843A patent/FR2415456A1/fr not_active Withdrawn
- 1979-01-24 GB GB7902460A patent/GB2014475B/en not_active Expired
- 1979-01-24 JP JP701079A patent/JPS54119798A/ja active Pending
- 1979-01-25 CA CA000320243A patent/CA1118155A/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB2014475B (en) | 1982-04-21 |
| BR7900377A (pt) | 1979-08-14 |
| DE2853614A1 (de) | 1979-07-26 |
| FR2415456A1 (fr) | 1979-08-24 |
| JPS54119798A (en) | 1979-09-17 |
| GB2014475A (en) | 1979-08-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |