CA1132046A - Combinaisons de 1,1-dioxyde d'acide penicillanique et d'acide 7-(d-2-¬4-ethylpiperazin-2,3-dione-1- carboxamido|-2-¬4-hydroxyphenyl|acetamido)-3- (¬1-methyl-5-tetrazolyl|thiomethyl) -3-desacetoxymethylcephalosporanique - Google Patents

Combinaisons de 1,1-dioxyde d'acide penicillanique et d'acide 7-(d-2-¬4-ethylpiperazin-2,3-dione-1- carboxamido|-2-¬4-hydroxyphenyl|acetamido)-3- (¬1-methyl-5-tetrazolyl|thiomethyl) -3-desacetoxymethylcephalosporanique

Info

Publication number
CA1132046A
CA1132046A CA331,436A CA331436A CA1132046A CA 1132046 A CA1132046 A CA 1132046A CA 331436 A CA331436 A CA 331436A CA 1132046 A CA1132046 A CA 1132046A
Authority
CA
Canada
Prior art keywords
ethyl
penicillanate
acid
dioxide
oxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA331,436A
Other languages
English (en)
Inventor
Wayne E. Barth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Ltd Great Britain
Original Assignee
Pfizer Ltd Great Britain
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/017,807 external-priority patent/US4276285A/en
Application filed by Pfizer Ltd Great Britain filed Critical Pfizer Ltd Great Britain
Application granted granted Critical
Publication of CA1132046A publication Critical patent/CA1132046A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA331,436A 1977-06-07 1979-07-09 Combinaisons de 1,1-dioxyde d'acide penicillanique et d'acide 7-(d-2-¬4-ethylpiperazin-2,3-dione-1- carboxamido|-2-¬4-hydroxyphenyl|acetamido)-3- (¬1-methyl-5-tetrazolyl|thiomethyl) -3-desacetoxymethylcephalosporanique Expired CA1132046A (fr)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US80432077A 1977-06-07 1977-06-07
US87938178A 1978-02-21 1978-02-21
US96376378A 1978-11-27 1978-11-27
US963,763 1978-11-27
US17,807 1979-03-05
US06/017,807 US4276285A (en) 1977-06-07 1979-03-05 Combinations of penicillanic acid 1,1-dioxide with 7-(D-2-[4-ethylpiperazin-2,3-dione-1-carboxamido]-2-[4-hydroxyphenyl]acetamido)-3-([1-methyl-5-tetrazolyl]thiomethyl)-3-desacetoxymethylcephalosporanic acid

Publications (1)

Publication Number Publication Date
CA1132046A true CA1132046A (fr) 1982-09-21

Family

ID=27486684

Family Applications (1)

Application Number Title Priority Date Filing Date
CA331,436A Expired CA1132046A (fr) 1977-06-07 1979-07-09 Combinaisons de 1,1-dioxyde d'acide penicillanique et d'acide 7-(d-2-¬4-ethylpiperazin-2,3-dione-1- carboxamido|-2-¬4-hydroxyphenyl|acetamido)-3- (¬1-methyl-5-tetrazolyl|thiomethyl) -3-desacetoxymethylcephalosporanique

Country Status (2)

Country Link
CA (1) CA1132046A (fr)
LU (1) LU81475A1 (fr)

Also Published As

Publication number Publication date
LU81475A1 (fr) 1980-02-14

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