CA1153761A - Methode de preparation de flunisolide - Google Patents

Methode de preparation de flunisolide

Info

Publication number
CA1153761A
CA1153761A CA000352333A CA352333A CA1153761A CA 1153761 A CA1153761 A CA 1153761A CA 000352333 A CA000352333 A CA 000352333A CA 352333 A CA352333 A CA 352333A CA 1153761 A CA1153761 A CA 1153761A
Authority
CA
Canada
Prior art keywords
flunisolide
solution
alkanol
water
butanol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000352333A
Other languages
English (en)
Inventor
Jacquelyn A. Smithers
Richard E. Jones
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Palo Alto LLC
Original Assignee
Roche Palo Alto LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Palo Alto LLC filed Critical Roche Palo Alto LLC
Application granted granted Critical
Publication of CA1153761A publication Critical patent/CA1153761A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA000352333A 1979-05-21 1980-05-21 Methode de preparation de flunisolide Expired CA1153761A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4083079A 1979-05-21 1979-05-21
US40,830 1979-05-21

Publications (1)

Publication Number Publication Date
CA1153761A true CA1153761A (fr) 1983-09-13

Family

ID=21913206

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000352333A Expired CA1153761A (fr) 1979-05-21 1980-05-21 Methode de preparation de flunisolide

Country Status (17)

Country Link
JP (1) JPS55154997A (fr)
AU (1) AU532084B2 (fr)
BE (1) BE883381A (fr)
CA (1) CA1153761A (fr)
CH (1) CH643567A5 (fr)
DE (1) DE3019250C2 (fr)
DK (1) DK162530C (fr)
FR (1) FR2457303A1 (fr)
GB (1) GB2052506B (fr)
HK (1) HK40784A (fr)
IL (1) IL60128A (fr)
IT (1) IT1133092B (fr)
MY (1) MY8500694A (fr)
NL (1) NL189201C (fr)
NZ (1) NZ193778A (fr)
SE (1) SE431549B (fr)
SG (1) SG37585G (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1121513B (it) * 1979-05-28 1986-04-02 Chiesi Farma Spa Processo per la conversione di umo steroide antiinfiammatorio in una forma suscettibile di essere somministarta come aerosol
GB8432063D0 (en) 1984-12-19 1985-01-30 Riker Laboratories Inc Physically modified steroids

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX3864E (es) * 1975-05-27 1981-08-26 Syntex Corp Un proceso para prepara el compuesto cristalino 6-fluiro-11b 21-dihiroxi-16 17-isopropilidendioxipregna-1 4-dien-3 20-diona

Also Published As

Publication number Publication date
CH643567A5 (de) 1984-06-15
DE3019250C2 (de) 1982-11-11
FR2457303B1 (fr) 1983-05-13
NL189201B (nl) 1992-09-01
NL8002902A (nl) 1980-11-25
IT1133092B (it) 1986-07-09
HK40784A (en) 1984-05-18
NL189201C (nl) 1993-02-01
MY8500694A (en) 1985-12-31
SG37585G (en) 1986-01-17
DK162530C (da) 1992-03-30
DK219280A (da) 1980-11-22
FR2457303A1 (fr) 1980-12-19
GB2052506B (en) 1983-01-19
IL60128A0 (en) 1980-07-31
IT8067791A0 (it) 1980-05-20
JPS55154997A (en) 1980-12-02
IL60128A (en) 1984-01-31
SE8003761L (sv) 1980-11-22
AU5856680A (en) 1980-11-27
JPS6258360B2 (fr) 1987-12-05
DE3019250A1 (de) 1980-12-04
SE431549B (sv) 1984-02-13
BE883381A (fr) 1980-11-20
AU532084B2 (en) 1983-09-15
GB2052506A (en) 1981-01-28
NZ193778A (en) 1982-03-16
DK162530B (da) 1991-11-11

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Legal Events

Date Code Title Description
MKEX Expiry