CA2000545A1 - Procede et reactif pour la determination d'une substance pouvant etre particulierement liaisonnee - Google Patents

Procede et reactif pour la determination d'une substance pouvant etre particulierement liaisonnee

Info

Publication number
CA2000545A1
CA2000545A1 CA2000545A CA2000545A CA2000545A1 CA 2000545 A1 CA2000545 A1 CA 2000545A1 CA 2000545 A CA2000545 A CA 2000545A CA 2000545 A CA2000545 A CA 2000545A CA 2000545 A1 CA2000545 A1 CA 2000545A1
Authority
CA
Canada
Prior art keywords
substance
labelling
determined
reagent
determination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2000545A
Other languages
English (en)
Other versions
CA2000545C (fr
Inventor
Roland Schenk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of CA2000545A1 publication Critical patent/CA2000545A1/fr
Application granted granted Critical
Publication of CA2000545C publication Critical patent/CA2000545C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/78—Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
CA002000545A 1988-10-12 1989-10-12 Procede et reactif pour la determination d'une substance pouvant etre particulierement liaisonnee Expired - Lifetime CA2000545C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3834766A DE3834766A1 (de) 1988-10-12 1988-10-12 Verfahren zur bestimmung einer spezifisch bindefaehigen substanz
DEP3834766.0 1988-10-12

Publications (2)

Publication Number Publication Date
CA2000545A1 true CA2000545A1 (fr) 1990-04-12
CA2000545C CA2000545C (fr) 2000-05-09

Family

ID=6364963

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002000545A Expired - Lifetime CA2000545C (fr) 1988-10-12 1989-10-12 Procede et reactif pour la determination d'une substance pouvant etre particulierement liaisonnee

Country Status (10)

Country Link
US (1) US5126241A (fr)
EP (1) EP0363942B1 (fr)
JP (1) JPH0814579B2 (fr)
KR (1) KR920005963B1 (fr)
AT (1) ATE101723T1 (fr)
AU (1) AU612907B2 (fr)
CA (1) CA2000545C (fr)
DE (2) DE3834766A1 (fr)
ES (1) ES2050200T3 (fr)
ZA (1) ZA897689B (fr)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3836348A1 (de) * 1988-10-25 1990-04-26 Boehringer Mannheim Gmbh Verfahren zur bestimmung von fuer ein antigen klassenspezifischen antikoerpern und dazu geeignetes reagenz
US5437981A (en) * 1990-02-26 1995-08-01 Boehringer Mannheim Gmbh Method for the immunological determination of ligands
US5792606A (en) * 1990-02-26 1998-08-11 Boehringer Mannheim Gmbh Nucleic acid hybridization based assay for determining a substance of interest
DE4006054A1 (de) * 1990-02-26 1991-08-29 Boehringer Mannheim Gmbh Verfahren zur immunologischen bestimmung von liganden
US5556748A (en) * 1991-07-30 1996-09-17 Xenopore Corporation Methods of sandwich hybridization for the quantitative analysis of oligonucleotides
DE4218257A1 (de) * 1992-06-03 1993-12-09 Behringwerke Ag Verfahren zur immunchemischen Bestimmung eines Analyten
DE4328070C1 (de) * 1993-08-20 1994-11-24 Henning Berlin Gmbh Verfahren zur Bestimmung eines Analyten in einem Volumen einer flüssigen Probe sowie seine Anwendung zur Bestimmung von anti-TSH-Rezeptor-Autoantikörpern in einem Patientenserum
US6991907B1 (en) * 1995-04-18 2006-01-31 Biosite, Inc. Methods for the assay of troponin I and T and complexes of troponin I and T and selection of antibodies for use in immunoassays
US6627404B1 (en) * 1995-04-18 2003-09-30 Biosite, Inc. Methods for improving the recovery of troponin I and T in membranes, filters and vessels
WO1997006439A1 (fr) 1995-08-09 1997-02-20 Quidel Corporation Lame d'epreuve et methode d'analyse en flux lateral en une seule etape
US5691152A (en) * 1995-11-09 1997-11-25 E. R. Squibb & Sons, Inc. Stable avidin composition
DE19548375A1 (de) * 1995-12-27 1997-07-03 Behringwerke Ag Immunologische Bestimmungsmethode
DE19548028A1 (de) * 1995-12-21 1997-06-26 Bayer Ag Verfahren zur Herstellung eines synthetischen Kalibrators für den Einsatz in Sandwich-Immunoassays, bestehend aus einem Antikörper gegen einen der im Assay benutzten Antikörper und einer Sequenz des Analyten
US5798273A (en) * 1996-09-25 1998-08-25 Becton Dickinson And Company Direct read lateral flow assay for small analytes
DE19808226C1 (de) * 1998-02-27 2000-03-02 Bruker Analytik Gmbh Anordnung und Verfahren zur Untersuchung von hydrophilen Makromolekülen in wässriger Lösung
US6699722B2 (en) 2000-04-14 2004-03-02 A-Fem Medical Corporation Positive detection lateral-flow apparatus and method for small and large analytes
WO2002090961A2 (fr) * 2001-05-03 2002-11-14 Immunetics, Inc. Systemes et procedes de detection d'analytes dans des liquides biologiques
EP2058663A1 (fr) 2007-11-12 2009-05-13 Euro-Diagnostica B.V. Procédé pour l'immobilisation d'un analyte sur un support solide
US7842475B2 (en) * 2008-01-08 2010-11-30 Siemens Healthcare Diagnostics Inc. Stabilization of solid support assay reagents
US8673644B2 (en) 2008-05-13 2014-03-18 Battelle Memorial Institute Serum markers for type II diabetes mellitus
US8476008B2 (en) * 2008-07-23 2013-07-02 Diabetomics, Llc Methods for detecting pre-diabetes and diabetes
US8168396B2 (en) 2009-05-11 2012-05-01 Diabetomics, Llc Methods for detecting pre-diabetes and diabetes using differential protein glycosylation
CA2800257C (fr) 2010-05-26 2019-03-05 The Board Of Trustees Of The University Of Illinois Glucometres personnels de detection et quantification de large gamme de substances a analyser
WO2013112216A1 (fr) 2012-01-24 2013-08-01 Cd Diagnostics, Llc Système de détection d'une infection dans le liquide synovial
US9383352B2 (en) 2014-03-26 2016-07-05 Diabetomics, Inc. Salivary protein glycosylation test for diagnosis and monitoring of diabetes
CA2983732A1 (fr) 2015-04-23 2016-10-27 Board Of Regents Of The Nevada System Of Higher Education, On Behalf Of The University Of Nevada, Reno Detection fongique a l'aide d'epitope de mannane
CA2994416A1 (fr) 2015-08-04 2017-02-09 Cd Diagnostics, Inc. Procedes de detection d'une necrose liee a une reaction locale indesirable sur les tissus (altr)
WO2017147186A1 (fr) 2016-02-22 2017-08-31 Ursure, Inc. Système et méthode de détection d'agents thérapeutiques pour surveiller l'adhésion à un schéma thérapeutique
ES2866880T3 (es) 2016-04-13 2021-10-20 Inst Nat Sante Rech Med Métodos y kits para la detección rápida del clon O25B-ST131 de Escherichia Coli
US11300576B2 (en) 2019-01-29 2022-04-12 Arizona Board Of Regents On Behalf Of Arizona State University DARPin reagents that distinguish Alzheimer's disease and Parkinson's disease samples

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE32696E (en) * 1975-09-04 1988-06-14 Akzona Incorporated Enzymatic immunological method for determination of antigens and antibodies
GB2084317B (en) * 1980-09-30 1984-01-18 Erba Farmitalia Antigen-linked competitive enzymeimmunoassay
US4737453A (en) * 1984-12-12 1988-04-12 Immunomedics, Inc. Sandwich immunoassay utilizing a separation specific binding substance
US4772550A (en) * 1986-02-10 1988-09-20 Miles Inc. Heterogeneous specific binding assay employing an aggregatable binding reagent
JPH02502122A (ja) * 1987-01-15 1990-07-12 ヘベイ，リチヤード・シー 液体中のリガンドを検出及び定量する方法
DE3705686C2 (de) * 1987-02-23 1995-11-30 Boehringer Mannheim Gmbh Verfahren zur Bestimmung von Antikörpern

Also Published As

Publication number Publication date
DE3834766A1 (de) 1990-04-26
CA2000545C (fr) 2000-05-09
JPH02156155A (ja) 1990-06-15
DE58906981D1 (de) 1994-03-24
EP0363942A3 (en) 1990-11-07
US5126241A (en) 1992-06-30
AU612907B2 (en) 1991-07-18
JPH0814579B2 (ja) 1996-02-14
KR920005963B1 (ko) 1992-07-25
ATE101723T1 (de) 1994-03-15
EP0363942A2 (fr) 1990-04-18
KR900006778A (ko) 1990-05-08
EP0363942B1 (fr) 1994-02-16
ES2050200T3 (es) 1994-05-16
ZA897689B (en) 1990-07-25
AU4285589A (en) 1990-04-26

Similar Documents

Publication Publication Date Title
CA2000545A1 (fr) Procede et reactif pour la determination d'une substance pouvant etre particulierement liaisonnee
DE3851967D1 (de) Verfahren zur Bestimmung von Antikörpern.
AU7727491A (en) Improvements in or relating to methods for providing internal references for use in analyte-receptor assays
CA2004878A1 (fr) Appareil et methode pour le dosage sequentiel d'un produit a analyser dans un echantillon liquide
HK1002814A1 (zh) 金蓮燈t之特別抗體，其生產及在測定心臟肌肉壞疽試劑中的使用
GB1488532A (en) Unitized solid phase immunoassay kit and method
AU2935989A (en) Test method and reagent kit therefor
EP0264219A3 (en) Receptors for immune complexes, their methods of production, compositions containing them, assay methods and assay kits using them
AU8814191A (en) Cell-free receptor binding assays, the production and use thereof
EP0214847A3 (en) Squarate dye conjugate, process for making it and its use in assay methods and kits
AU3785289A (en) Process and reagent for the determination of a specifically bindable substance
ZA896535B (en) Process for the determination of a specifically bindable substance
EP0028132A3 (fr) Procédé pour l'adsorption passive d'haptènes à activité immunologique sur phases solides
AU1815592A (en) Free-species analyte assay
AU618137B2 (en) Process for the determination of antibodies which are class-specific for an antigen and a reagent for carrying out the process
EP0161107A3 (fr) Méthode immunométrique pour la détermination d'un haptène
AU657719B2 (en) Methods for determination of an analyte
EP0289003A3 (fr) Méthode immunologique et réactif pour la détermination d'un antigène polyvalent dans un échantillon liquide
AU4440096A (en) Competitive immunoassay using complexed analyte derivatives
GB2214295B (en) "hapten determination method, use and components"
EP0540037A3 (fr)
KR910021586A (ko) 리간드의 면역학적 검출방법
AU6205290A (en) Method for the detection of analytes
Tiefenauer et al. Antibody coating using various avidin-biotin complexes employed to an enzyme immunoassay for estradiol
EP0379347A3 (fr) Composition de récepteur margue par une enzyme, trousse diagnostique et son utilisation pour déterminer un ligand

Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry