CA2013755A1 - Emulsions medicinales - Google Patents

Emulsions medicinales

Info

Publication number
CA2013755A1
CA2013755A1 CA2013755A CA2013755A CA2013755A1 CA 2013755 A1 CA2013755 A1 CA 2013755A1 CA 2013755 A CA2013755 A CA 2013755A CA 2013755 A CA2013755 A CA 2013755A CA 2013755 A1 CA2013755 A1 CA 2013755A1
Authority
CA
Canada
Prior art keywords
composition
oil
ionic surfactant
combination
lypophilic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2013755A
Other languages
English (en)
Other versions
CA2013755C (fr
Inventor
Simon Benita
Menashe Levy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yissum Research Development Co of Hebrew University of Jerusalem
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26321921&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2013755(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from IL89856A external-priority patent/IL89856A/xx
Priority claimed from IL9355890A external-priority patent/IL93558A/en
Application filed by Individual filed Critical Individual
Publication of CA2013755A1 publication Critical patent/CA2013755A1/fr
Application granted granted Critical
Publication of CA2013755C publication Critical patent/CA2013755C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Fats And Perfumes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA002013755A 1989-04-05 1990-04-03 Emulsions medicinales Expired - Fee Related CA2013755C (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IL89856 1989-04-05
IL89856A IL89856A (en) 1989-04-05 1989-04-05 Medical emulsions for liphophilic drugs containing a medium-chain triglyceride oil as a carrier
IL9355890A IL93558A (en) 1990-02-27 1990-02-27 Process for the preparation of medicinal composition in the form of oil-in-water emulsion comprising a lipophilic drug
IL93558 1990-02-27

Publications (2)

Publication Number Publication Date
CA2013755A1 true CA2013755A1 (fr) 1990-10-05
CA2013755C CA2013755C (fr) 1993-11-30

Family

ID=26321921

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002013755A Expired - Fee Related CA2013755C (fr) 1989-04-05 1990-04-03 Emulsions medicinales

Country Status (6)

Country Link
EP (1) EP0391369B1 (fr)
JP (1) JPH07121857B2 (fr)
AT (1) ATE110563T1 (fr)
AU (1) AU614465B2 (fr)
CA (1) CA2013755C (fr)
DE (1) DE69011922T2 (fr)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
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US5278151A (en) * 1987-04-02 1994-01-11 Ocular Research Of Boston, Inc. Dry eye treatment solution
US5364632A (en) * 1989-04-05 1994-11-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem Medicinal emulsions
FR2649012B1 (fr) * 1989-07-03 1991-10-25 Seppic Sa Emulsions multiphasiques injectables
US5750134A (en) 1989-11-03 1998-05-12 Riker Laboratories, Inc. Bioadhesive composition and patch
ATE132366T1 (de) * 1990-05-29 1996-01-15 Boston Ocular Res Zusammensetzung zur behandlung von dry eye erkrankungen
ZA912797B (en) * 1990-05-29 1992-12-30 Boston Ocular Res Dry eye treatment process and solution
US5534502A (en) * 1990-11-06 1996-07-09 Nippon Shinyaku Co. Ltd. Process for producing fat emulsion
JP2653246B2 (ja) * 1990-11-06 1997-09-17 日本新薬株式会社 脂肪乳剤の製法
EP0556392A4 (fr) * 1990-11-06 1994-03-17 Nippon Shinyaku Co Ltd Procede de production d'une emulsion grasse.
IL98747A0 (en) * 1991-07-05 1992-07-15 Yissum Res Dev Co Ophthalmic compositions
IL101241A (en) * 1992-03-16 1997-11-20 Yissum Res Dev Co Pharmaceutical or cosmetic composition comprising stabilized oil-in-water type emulsion as carrier
IL101387A (en) * 1992-03-26 1999-11-30 Pharmos Ltd Emulsion with enhanced topical and/or transdermal systemic effect utilizing submicron oil droplets
US5637317A (en) * 1992-05-18 1997-06-10 Dietl; Hans Pharmaceutical preparation containing cyclosporin(s) for oral administration and process for producing same
US5527537A (en) * 1992-05-18 1996-06-18 Dietl; Hans Pharmaceutical preparation containing cyclosporine(s) for intravenous administration and a process for its production
US5529785A (en) * 1993-05-12 1996-06-25 Dietl; Hans Pharmaceutical preparation containing cyclosporin(s) for oral administration and process for producing same
GB9212511D0 (en) * 1992-06-12 1992-07-22 Cortecs Ltd Pharmaceutical compositions
US5674855A (en) * 1992-08-12 1997-10-07 The Rogosin Institute Methods and compositions useful in prophylaxis and therapy of endotoxin related conditions
AU680813B2 (en) * 1992-08-28 1997-08-14 Pharmos Corporation Submicron emulsions as ocular drug delivery vehicles
US6113921A (en) * 1993-03-23 2000-09-05 Pharmos Corp. Topical and transdermal delivery system utilizing submicron oil spheres
SE9301171D0 (sv) * 1993-04-07 1993-04-07 Ab Astra Pharmaceutical composition containing lipophilic drugs
DE4338086A1 (de) * 1993-11-08 1995-05-11 Dietl Hans Cyclosporin(e) enthaltende pharmazeutische Zubereitung zur oralen Applikation sowie Verfahren zu ihrer Herstellung
SE9302295D0 (sv) * 1993-07-02 1993-07-02 Kabi Pharmacia Ab New pharmaceutical composition
IL106578A (en) * 1993-08-03 2000-08-13 Yissum Res Dev Co Pharmaceutical compositions for drug targeting
DE4338046A1 (de) * 1993-11-08 1995-05-11 Dietl Hans Fettlösliche Arzneimittel erhaltende flüssige pharmazeutische Zubereitung zur oralen Anwendung
SE518823C2 (sv) * 1994-07-12 2002-11-26 Karlshamns Lipidteknik Ab Olja-i-vatten-emulsioner
WO1995022343A1 (fr) * 1994-02-17 1995-08-24 Shiseido Company, Ltd. Composition d'emulsion a base de cyclosporine
DE4432440A1 (de) * 1994-05-20 1995-11-23 Medizinische Forschung Und Wei Lorazepam- bzw. lormetazepamhaltige therapeutische Zusammensetzung, insbesondere Sedativum
ES2206473T3 (es) * 1994-05-20 2004-05-16 Gesellschaft Fur Medizinische Forschung Und Weiterbildung E.V. Gmf Emulsion de aceite en agua que contiene lormetazepam.
SE9403389D0 (sv) * 1994-10-06 1994-10-06 Astra Ab Pharmaceutical composition containing derivattves of sex hormones
HU215966B (hu) * 1994-11-21 1999-07-28 BIOGAL Gyógyszergyár Rt. Orálisan alkalmazható, ciklosporint tartalmazó, összetett emulzió-előkoncentrátum
US5635536A (en) * 1994-12-07 1997-06-03 Pharmacia & Upjohn Aktiebolag Emulsion suitable for administering a sphingolipid
DE19511322C2 (de) 1995-03-28 1999-09-02 Mann Gerhard Chem Pharm Fab Sterile Augengele mit einem Gehalt an mittelkettigen Triglyceriden und Verfahren zu deren Herstellung
US5616342A (en) * 1995-04-11 1997-04-01 Pdt, Inc. Emulsioin suitable for administering a poorly water-soluble photosensitizing compound and use thereof
GB2317562B (en) * 1995-07-20 1999-08-18 Danbiosyst Uk Lipid vehicle drug delivery composition containing vitamin E
GB9514878D0 (en) * 1995-07-20 1995-09-20 Danbiosyst Uk Vitamin E as a solubilizer for drugs contained in lipid vehicles
SE9503143D0 (sv) 1995-09-12 1995-09-12 Astra Ab New preparation
ES2138130T3 (es) 1995-10-28 2000-01-01 Braun Melsungen Ag Composicion farmaceutica que contiene un anestesico local y/o un analgesico de accion central.
US5660858A (en) * 1996-04-03 1997-08-26 Research Triangle Pharmaceuticals Cyclosporin emulsions
US6465016B2 (en) 1996-08-22 2002-10-15 Research Triangle Pharmaceuticals Cyclosporiine particles
US7255877B2 (en) 1996-08-22 2007-08-14 Jagotec Ag Fenofibrate microparticles
WO1998007414A1 (fr) * 1996-08-22 1998-02-26 Research Triangle Pharmaceuticals Ltd. Compositions comprenant des microparticules de substances insolubles dans l'eau et procede de preparation associe
EP0865792A1 (fr) * 1997-03-17 1998-09-23 Rotkreuzstiftung Zentrallaboratorium Blutspendedienst Srk Composition pharmaceutique contenant des immunoglobulines pour l'usage topique
EP0872229A1 (fr) * 1997-04-14 1998-10-21 Janssen Pharmaceutica N.V. Compositions contenant un agent antifongique et un phospholipide
US6281175B1 (en) 1997-09-23 2001-08-28 Scimed Life Systems, Inc. Medical emulsion for lubrication and delivery of drugs
US6054421A (en) * 1997-09-23 2000-04-25 Scimed Life Systems, Inc. Medical emulsion lubricant
GB9721746D0 (en) * 1997-10-15 1997-12-10 Panos Therapeutics Limited Compositions
GB9724786D0 (en) * 1997-11-25 1998-01-21 Danbiosyst Uk Oral delivery system
US6979456B1 (en) 1998-04-01 2005-12-27 Jagotec Ag Anticancer compositions
ES2216517T3 (es) 1998-05-29 2004-10-16 Skyepharma Canada Inc. Composiciones de microcapsulas termoprotegidas y procedimiento para su esterilizacion terminal con vapor.
GB9817650D0 (en) * 1998-08-14 1998-10-07 Danbiosyst Uk Oral formulation
EP1105096B1 (fr) 1998-08-19 2003-10-29 Skyepharma Canada Inc. Dispersions aqueuses injectables de propofol
IL143197A0 (en) 1998-11-20 2002-04-21 Rtp Pharma Inc Dispersible phospholipid stabilized microparticles
WO2000040219A1 (fr) 1998-12-30 2000-07-13 Dexcel Ltd. Concentre dispersable destine a l'administration d'une cyclosporine
US6447806B1 (en) 1999-02-25 2002-09-10 Novartis Ag Pharmaceutical compositions comprised of stabilized peptide particles
GB2350297A (en) * 1999-05-27 2000-11-29 Abbott Lab Injectable halogenated anesthetic formulation in emulsion form
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
DE10030378A1 (de) * 2000-06-21 2002-03-14 Audit Inst For Medical Service Neue pharmazeutische Zusammensetzung zur topischen Anwendung von wasserunlöslichen und/oder schwer wasserlöslichen Wirkstoffen
IN188843B (fr) * 2000-06-22 2002-11-09 Vinod Daftary Gautam Dr
KR100423895B1 (ko) * 2001-02-19 2004-03-24 주식회사 엘지생명과학 셉티오퍼 하이드로클로라이드의 현탁제 조성물
GB0116107D0 (en) * 2001-06-30 2001-08-22 West Pharm Serv Drug Res Ltd Pharmaceutical composition
EP1488785A1 (fr) * 2003-06-18 2004-12-22 B. Braun Melsungen Ag Emulsion à l'huile pour la substitution postnatale des hormones
US9161905B2 (en) 2005-01-12 2015-10-20 Ocular Research Of Boston, Inc. Dry eye treatment
US9918934B2 (en) * 2006-12-12 2018-03-20 Edgar Joel Acosta-Zara Linker-based lecithin microemulsion delivery vehicles
EP2155255B1 (fr) * 2007-05-09 2013-08-14 Nitto Denko Corporation Compositions comprenant un composé hydrophobe et un conjugué polyamino acide
MX2011001241A (es) * 2008-08-01 2011-08-03 Medicines Co Composiciones farmaceuticas y metodos para estabilizar las mismas.
IT1393419B1 (it) 2009-03-19 2012-04-20 Medivis S R L Composizioni oftalmiche a base di acidi grassi polinsaturi omega-3 e omega-6.
FR2962044B1 (fr) * 2010-04-21 2013-02-22 Horus Pharma Emulsion lacrymimetique
IT1404931B1 (it) 2010-06-11 2013-12-09 Medivis S R L Composizioni oftalmiche per la somministrazione di principi attivi liposolubili .
MX369121B (es) 2011-03-04 2019-10-30 Gruenenthal Gmbh Formulacion farmaceutica acuosa de tapentadol para administracion oral.
MY167596A (en) * 2011-12-23 2018-09-20 Bayer New Zealand Ltd Antibiotic formulations
EA036258B1 (ru) 2015-03-27 2020-10-20 Грюненталь Гмбх Стабильный препарат для парентерального введения тапентадола
CN105193722B (zh) * 2015-10-28 2021-12-14 辅必成（上海）医药科技有限公司 二巯丙醇脂肪乳注射液
CN109996533A (zh) 2016-09-23 2019-07-09 格吕伦塔尔有限公司 用于肠胃外施用他喷他多的稳定制剂
CN111867562B (zh) * 2018-03-07 2023-07-07 陈献 不溶性药物的水性制剂
AU2019396217A1 (en) * 2018-12-10 2021-07-08 Halo Science LLC Stable formulations of anesthetics and associated dosage forms

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115313A (en) * 1974-10-08 1978-09-19 Irving Lyon Bile acid emulsions
FR2619505B1 (fr) * 1987-08-20 1990-08-31 Dior Christian Parfums Composition a base de phases lamellaires lipidiques hydratees ou de liposomes contenant de la pregnenolone ou un ester de pregnenolone, et composition cosmetique ou pharmaceutique, notamment dermatologique, a activite regeneratrice ou revitalisante, l'incorporant
CA1337397C (fr) * 1988-09-29 1995-10-24 Hideo Nakajima Composition emulsifiee

Also Published As

Publication number Publication date
CA2013755C (fr) 1993-11-30
EP0391369A3 (fr) 1991-04-24
JPH02290809A (ja) 1990-11-30
ATE110563T1 (de) 1994-09-15
DE69011922T2 (de) 1995-01-12
AU5292790A (en) 1990-10-11
EP0391369B1 (fr) 1994-08-31
AU614465B2 (en) 1991-08-29
JPH07121857B2 (ja) 1995-12-25
DE69011922D1 (de) 1994-10-06
EP0391369A2 (fr) 1990-10-10

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