CA2014202A1 - Derives imidazole substitues par deux atomes de chlore utilises comme agents antifongiques - Google Patents

Derives imidazole substitues par deux atomes de chlore utilises comme agents antifongiques

Info

Publication number
CA2014202A1
CA2014202A1 CA2014202A CA2014202A CA2014202A1 CA 2014202 A1 CA2014202 A1 CA 2014202A1 CA 2014202 A CA2014202 A CA 2014202A CA 2014202 A CA2014202 A CA 2014202A CA 2014202 A1 CA2014202 A1 CA 2014202A1
Authority
CA
Canada
Prior art keywords
dichloro
products
formula
antifungal agents
imidazole derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2014202A
Other languages
English (en)
Other versions
CA2014202C (fr
Inventor
Romeo Andreoli Rovatti
Ricardo Cepero Mestres
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorios Salvat SA
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2014202A1 publication Critical patent/CA2014202A1/fr
Application granted granted Critical
Publication of CA2014202C publication Critical patent/CA2014202C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
CA002014202A 1989-04-10 1990-04-09 Derives imidazole substitues par deux atomes de chlore utilises comme agents antifongiques Expired - Lifetime CA2014202C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES8901237A ES2012297A6 (es) 1989-04-10 1989-04-10 Procedimiento para la obtencion de nuevos derivados imidazolicos diclorados con actividad antifungica.
ES8901237 1989-04-10

Publications (2)

Publication Number Publication Date
CA2014202A1 true CA2014202A1 (fr) 1990-10-10
CA2014202C CA2014202C (fr) 1997-02-04

Family

ID=8261371

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002014202A Expired - Lifetime CA2014202C (fr) 1989-04-10 1990-04-09 Derives imidazole substitues par deux atomes de chlore utilises comme agents antifongiques

Country Status (14)

Country Link
EP (1) EP0392326B1 (fr)
JP (1) JP2798094B2 (fr)
KR (1) KR960007164B1 (fr)
AT (1) ATE108778T1 (fr)
AU (1) AU627010B2 (fr)
CA (1) CA2014202C (fr)
DE (1) DE69010729T2 (fr)
DK (1) DK0392326T3 (fr)
ES (2) ES2012297A6 (fr)
HK (1) HK1007429A1 (fr)
LV (1) LV11461B (fr)
NZ (1) NZ233269A (fr)
PT (1) PT93707B (fr)
ZA (1) ZA902709B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8980930B2 (en) 2004-06-25 2015-03-17 The Johns Hopkins University Angiogenesis inhibitors

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2092957B1 (es) * 1994-11-28 1997-08-01 S A L V A T Lab Sa Procedimiento de preparacion de intermedios para la sintesis de derivados dicloro-substituidos con actividad antifungica.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1593417A (en) * 1976-12-22 1981-07-15 Squibb & Sons Inc Carbocyclic-fused pyrazolopyridine derivatives
US4826853A (en) * 1986-10-31 1989-05-02 Schering Corporation 6,11-Dihydro-11-(N-substituted-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines and compositions and methods of use

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8980930B2 (en) 2004-06-25 2015-03-17 The Johns Hopkins University Angiogenesis inhibitors
US9642865B2 (en) 2004-06-25 2017-05-09 The Johns Hopkins University Angiogenesis inhibitors

Also Published As

Publication number Publication date
DK0392326T3 (da) 1994-08-22
LV11461B (en) 1997-02-20
DE69010729T2 (de) 1994-11-24
KR960007164B1 (ko) 1996-05-29
ES2012297A6 (es) 1990-03-01
DE69010729D1 (de) 1994-08-25
EP0392326B1 (fr) 1994-07-20
ES2057235T3 (es) 1994-10-16
EP0392326A1 (fr) 1990-10-17
KR900016143A (ko) 1990-11-12
ATE108778T1 (de) 1994-08-15
ZA902709B (en) 1991-01-30
AU5255490A (en) 1990-10-11
PT93707A (pt) 1990-11-20
JP2798094B2 (ja) 1998-09-17
NZ233269A (en) 1991-08-27
PT93707B (pt) 1996-08-30
CA2014202C (fr) 1997-02-04
JPH0372462A (ja) 1991-03-27
LV11461A (lv) 1996-08-20
AU627010B2 (en) 1992-08-13
HK1007429A1 (en) 1999-04-09

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Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry