CA2016646A1 - Arylsulphonamides - Google Patents

Arylsulphonamides

Info

Publication number: CA2016646A1
Authority: CA; Canada
Prior art keywords: thromboxane; addition salts; arylsulphonamides; carbon; novel
Prior art date: 1989-05-12
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

CA2016646A

Other languages

English (en)

Other versions

CA2016646C (fr

Inventor

Armin Heckel

Josef Nickl (Deceased)

Rainer Soyka

Wolfgang Eisert

Thomas Muller

Johannes Weisenberger

Christopher Meade

Gojko Muacevic

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Boehringer Ingelheim Pharma GmbH and Co KG

Original Assignee

Dr Karl Thomae GmbH

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-05-12

Filing date

1990-05-11

Publication date

1990-11-12

1989-05-12 Priority claimed from DE3915506A external-priority patent/DE3915506A1/de

1990-05-11 Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH

1990-11-12 Publication of CA2016646A1 publication Critical patent/CA2016646A1/fr

1999-09-07 Application granted granted Critical

1999-09-07 Publication of CA2016646C publication Critical patent/CA2016646C/fr

2010-05-11 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

125000004421 aryl sulphonamide group Chemical group 0.000 title abstract 2
RZWIIPASKMUIAC-VQTJNVASSA-N thromboxane Chemical compound CCCCCCCC[C@H]1OCCC[C@@H]1CCCCCCC RZWIIPASKMUIAC-VQTJNVASSA-N 0.000 abstract 3
230000000694 effects Effects 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
239000005557 antagonist Substances 0.000 abstract 1
230000002785 anti-thrombosis Effects 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
239000011203 carbon fibre reinforced carbon Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
XEYBRNLFEZDVAW-ARSRFYASSA-N dinoprostone Chemical compound CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O XEYBRNLFEZDVAW-ARSRFYASSA-N 0.000 abstract 1
229960002986 dinoprostone Drugs 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1
150000007529 inorganic bases Chemical class 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
230000001404 mediated effect Effects 0.000 abstract 1
150000007530 organic bases Chemical class 0.000 abstract 1
230000000144 pharmacologic effect Effects 0.000 abstract 1
XEYBRNLFEZDVAW-UHFFFAOYSA-N prostaglandin E2 Natural products CCCCCC(O)C=CC1C(O)CC(=O)C1CC=CCCCC(O)=O XEYBRNLFEZDVAW-UHFFFAOYSA-N 0.000 abstract 1
238000003786 synthesis reaction Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/55—Acids; Esters
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/56—Amides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pulmonology (AREA)
Vascular Medicine (AREA)
Diabetes (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Immunology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pyridine Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Pyrrole Compounds (AREA)

CA002016646A 1989-05-12 1990-05-11 Arylsulphonamides Expired - Fee Related CA2016646C (fr)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
DE3915506A DE3915506A1 (de)	1989-05-12	1989-05-12	Neue arylsulfonamide, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
DEP3915506.4		1989-05-12
DEP3932403.6		1989-09-28
DE3932403A DE3932403A1 (de)	1989-05-12	1989-09-28	Neue arylsulfonamide, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung

Publications (2)

Publication Number	Publication Date
CA2016646A1 true CA2016646A1 (fr)	1990-11-12
CA2016646C CA2016646C (fr)	1999-09-07

Family

ID=25880794

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002016646A Expired - Fee Related CA2016646C (fr)	1989-05-12	1990-05-11	Arylsulphonamides

Country Status (21)

Country	Link
US (3)	US5294626A (fr)
EP (1)	EP0397044B1 (fr)
JP (1)	JP2868283B2 (fr)
KR (1)	KR0153527B1 (fr)
AT (1)	ATE132138T1 (fr)
AU (1)	AU627024B2 (fr)
CA (1)	CA2016646C (fr)
DE (2)	DE3932403A1 (fr)
DK (1)	DK0397044T3 (fr)
ES (1)	ES2083394T3 (fr)
FI (1)	FI95372C (fr)
GR (1)	GR3019044T3 (fr)
HU (1)	HU214586B (fr)
IE (1)	IE74207B1 (fr)
IL (1)	IL94347A0 (fr)
MX (1)	MX9202816A (fr)
NO (1)	NO176176C (fr)
NZ (1)	NZ233638A (fr)
PT (1)	PT93994B (fr)
RU (1)	RU2096405C1 (fr)
UA (1)	UA26136C2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5457118A (en) *	1991-04-04	1995-10-10	Pfizer Inc.	Pyridine derived agents for cardiovascular diseases

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5153214A (en) *	1989-06-28	1992-10-06	Ciba-Geigy Corporation	Certain (arylsulfonamido- and imidazolyl-)-substituted carboxylic acids and derivatives thereof and use for suppressing thromboxane activity
DE4025818A1 (de) *	1990-08-16	1992-02-20	Bayer Ag	Phenylsulfonamid substituierte pyridinalken- und -aminooxyalkancarbonsaeure-derivate
US5286736A (en) *	1990-11-22	1994-02-15	Dr. Karl Thomae Gmbh	Pyridyl compounds and pharmaceutical compositions containing these compounds
DE4037112A1 (de) *	1990-11-22	1992-05-27	Thomae Gmbh Dr K	Neue pyridylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
US5374641A (en) *	1991-02-25	1994-12-20	Terumo Kabushiki Kaisha	N-(3-pyridylalkyl)sulfonamide compounds which have useful pharmaceutical activity
DE4216364A1 (de) *	1991-12-14	1993-11-25	Thomae Gmbh Dr K	Neue Pyridylderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
FR2686339B1 (fr) *	1992-01-22	1994-03-11	Adir Cie	Nouveaux amides et sulfonamides naphtaleniques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
DE4213919A1 (de) *	1992-04-28	1993-11-04	Thomae Gmbh Dr K	Cyclische iminoderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
CA2347939C (fr)	1998-10-23	2006-10-10	Akira Matsumori	Composition pour le traitement du rhumatisme, de l'hepatite ou de la pancreatite
YU78601A (sh) *	1999-05-05	2005-07-19	Aventis Pharma Deutschland Gmbh.	1-(p-tienilbenzil)-imidazoli kao agonisti angiotenzin-(1-7)- receptora, postupak za njihovu proizvodnju, njihova primena i farmaceutski preparati koji ih sadrže
AU2010233694A1 (en)	2009-04-09	2011-09-29	Merck Sharp & Dohme B.V.	Indane derivatives
CN102655866B (zh)	2009-11-13	2013-11-13	东丽株式会社	糖尿病的治疗或预防药
US9955802B2 (en)	2015-04-08	2018-05-01	Fasteners For Retail, Inc.	Divider with selectively securable track assembly

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1134828A (fr) *	1978-12-28	1982-11-02	Tadao Tanouchi	Derives de la pyridine
DE3373467D1 (en) *	1982-06-14	1987-10-15	Takeda Chemical Industries Ltd	Vinyl carboxylic acid derivatives, their production and use
US4518602A (en) *	1982-10-07	1985-05-21	Takeda Chemical Industries, Ltd.	Vinyl carboxylic acid derivatives, their production and use as inhibitors of thromboxane synthetase
US4563446A (en) *	1983-07-27	1986-01-07	Takeda Chemical Industries, Ltd.	Thromboxane synthetase inhibiting 3-(1-alkenyl) pyridines
ES2061432T3 (es) *	1985-10-09	1994-12-16	Shell Int Research	Nuevas amidas de acido acrilico.
DE3623944A1 (de) *	1986-07-16	1988-02-11	Thomae Gmbh Dr K	Neue benzolsulfonamido-indanylverbindungen, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
GB8708233D0 (en) *	1987-04-07	1987-05-13	Smith Kline French Lab	Pharmaceutically active compounds
EP0304271A3 (fr) *	1987-08-20	1992-09-02	Smith Kline & French Laboratories Limited	Acides oméga-arylsulphonamidoalkanoiques pour le traitement de maladies par médiation du thromboxane

1989
- 1989-09-28 DE DE3932403A patent/DE3932403A1/de not_active Withdrawn
1990
- 1990-05-04 DE DE59009994T patent/DE59009994D1/de not_active Expired - Fee Related
- 1990-05-04 EP EP90108433A patent/EP0397044B1/fr not_active Expired - Lifetime
- 1990-05-04 DK DK90108433.5T patent/DK0397044T3/da active
- 1990-05-04 ES ES90108433T patent/ES2083394T3/es not_active Expired - Lifetime
- 1990-05-04 AT AT90108433T patent/ATE132138T1/de not_active IP Right Cessation
- 1990-05-10 IL IL94347A patent/IL94347A0/xx not_active IP Right Cessation
- 1990-05-10 PT PT93994A patent/PT93994B/pt not_active IP Right Cessation
- 1990-05-10 KR KR1019900006587A patent/KR0153527B1/ko not_active Expired - Fee Related
- 1990-05-10 NZ NZ233638A patent/NZ233638A/en unknown
- 1990-05-11 CA CA002016646A patent/CA2016646C/fr not_active Expired - Fee Related
- 1990-05-11 JP JP2122825A patent/JP2868283B2/ja not_active Expired - Lifetime
- 1990-05-11 HU HU903013A patent/HU214586B/hu not_active IP Right Cessation
- 1990-05-11 IE IE170890A patent/IE74207B1/en not_active IP Right Cessation
- 1990-05-11 NO NO902099A patent/NO176176C/no not_active IP Right Cessation
- 1990-05-11 AU AU54924/90A patent/AU627024B2/en not_active Ceased
- 1990-05-11 FI FI902358A patent/FI95372C/fi not_active IP Right Cessation
- 1990-05-14 US US07/523,167 patent/US5294626A/en not_active Expired - Fee Related
1992
- 1992-01-08 RU SU925010477A patent/RU2096405C1/ru active
- 1992-06-12 MX MX9202816A patent/MX9202816A/es unknown
1993
- 1993-05-12 UA UA93002789A patent/UA26136C2/uk unknown
- 1993-11-18 US US08/154,647 patent/US5426119A/en not_active Expired - Fee Related
1995
- 1995-03-21 US US08/407,180 patent/US5681961A/en not_active Expired - Fee Related
1996
- 1996-02-21 GR GR960400447T patent/GR3019044T3/el unknown

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5457118A (en) *	1991-04-04	1995-10-10	Pfizer Inc.	Pyridine derived agents for cardiovascular diseases

Also Published As

Publication number	Publication date
DK0397044T3 (da)	1996-05-13
CA2016646C (fr)	1999-09-07
DE59009994D1 (de)	1996-02-08
GR3019044T3 (en)	1996-05-31
IE74207B1 (en)	1997-07-16
JP2868283B2 (ja)	1999-03-10
FI902358A0 (fi)	1990-05-11
KR900018031A (ko)	1990-12-20
FI95372C (fi)	1996-01-25
JPH035457A (ja)	1991-01-11
EP0397044B1 (fr)	1995-12-27
NZ233638A (en)	1992-03-26
ATE132138T1 (de)	1996-01-15
EP0397044A2 (fr)	1990-11-14
IE901708L (en)	1990-11-12
FI95372B (fi)	1995-10-13
IL94347A0 (en)	1991-03-10
KR0153527B1 (ko)	1998-11-16
US5681961A (en)	1997-10-28
NO902099D0 (no)	1990-05-11
US5294626A (en)	1994-03-15
RU2096405C1 (ru)	1997-11-20
HU214586B (hu)	1998-04-28
PT93994B (pt)	1997-04-30
PT93994A (pt)	1991-01-08
NO176176B (no)	1994-11-07
HUT54649A (en)	1991-03-28
EP0397044A3 (fr)	1991-10-16
AU627024B2 (en)	1992-08-13
HU903013D0 (en)	1990-09-28
IE901708A1 (en)	1991-06-19
UA26136C2 (uk)	1999-06-07
MX9202816A (es)	1992-06-30
NO176176C (no)	1995-02-15
ES2083394T3 (es)	1996-04-16
NO902099L (no)	1990-11-13
AU5492490A (en)	1990-11-15
US5426119A (en)	1995-06-20
DE3932403A1 (de)	1991-04-11

Legal Events

Date	Code	Title	Description
1996-12-02	EEER	Examination request
2001-05-11	MKLA	Lapsed

Publication	Publication Date	Title
CA2016646A1 (fr)	1990-11-12	Arylsulphonamides
CA2067877A1 (fr)	1992-11-04	Composes amines polycliques et leurs enantiomeres; methode de preparation; compositions pharmaceutiques qui en renferment
NO924598L (no)	1992-11-27	Fremstilling av substituerte piperidiner
RU94036749A (ru)	1996-10-10	Замещенные 1-нафтилпиразол-3-карбоксамиды, способ их получения, содержащие их фармацевтические композиции и промежуточные соединения синтеза
AU640063B2 (en)	1993-08-12	Pyridyl derivatives
ATE100102T1 (de)	1994-01-15	Substituierte derivate von 20,21dinoreburnamenin, verfahren zur herstellung und so hergestellte zwischenprodukte, ihre verwendung als arzneimittel und diese enthaltende pharmazeutische zusammenstellungen.
DK0815109T3 (da)	2001-11-05	Fremgangsmåde til fremstilling af estere af anhydroecgonin
HUT59399A (en)	1992-05-28	Process for producing substituted 3-aminosydnone imine derivatives and pharmaceutical compositions comprising same
RU93045455A (ru)	1996-07-20	Производные пиперидина, способ их получения и фармацевтическая композиция на их основе
AU1976588A (en)	1989-02-02	Novel (aryl or heteroaromatic methyl)-2,2'-bi-1h- imidazoles

CA2016646A1 - Arylsulphonamides - Google Patents

Info

Links

Classifications

Landscapes

Applications Claiming Priority (4)

Publications (2)

Family

ID=25880794

Family Applications (1)

Country Status (21)

Cited By (1)

Families Citing this family (13)

Family Cites Families (8)

Cited By (1)

Also Published As

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Legal Events