CA2016841C - Methode de production de polymeres ayant une activite choisie - Google Patents

Methode de production de polymeres ayant une activite choisie

Info

Publication number
CA2016841C
CA2016841C CA 2016841 CA2016841A CA2016841C CA 2016841 C CA2016841 C CA 2016841C CA 2016841 CA2016841 CA 2016841 CA 2016841 A CA2016841 A CA 2016841A CA 2016841 C CA2016841 C CA 2016841C
Authority
CA
Canada
Prior art keywords
coding
primers
dna
antibody
repertoire
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA 2016841
Other languages
English (en)
Other versions
CA2016841A1 (fr
Inventor
William D. Huse
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Original Assignee
Scripps Clinic and Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic and Research Foundation filed Critical Scripps Clinic and Research Foundation
Publication of CA2016841A1 publication Critical patent/CA2016841A1/fr
Application granted granted Critical
Publication of CA2016841C publication Critical patent/CA2016841C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • External Artificial Organs (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA 2016841 1989-05-16 1990-05-15 Methode de production de polymeres ayant une activite choisie Expired - Lifetime CA2016841C (fr)

Applications Claiming Priority (22)

Application Number Priority Date Filing Date Title
US35323589A 1989-05-16 1989-05-16
US35292789A 1989-05-16 1989-05-16
US07/352,927 1989-05-16
US07/353,235 1989-05-16
US35288489A 1989-05-17 1989-05-17
US35324189A 1989-05-17 1989-05-17
US07/352,884 1989-05-17
US07/353,241 1989-05-17
US41073589A 1989-09-20 1989-09-20
US41071689A 1989-09-20 1989-09-20
US41088889A 1989-09-20 1989-09-20
US41074989A 1989-09-20 1989-09-20
US07/410,716 1989-09-20
US07/410,888 1989-09-20
US07/410,735 1989-09-20
US07/410,749 1989-09-20
US41105889A 1989-09-21 1989-09-21
US07/411,058 1989-09-21
US44633389A 1989-12-04 1989-12-04
US07/446,333 1989-12-04
US49710690A 1990-03-20 1990-03-20
US07/497,106 1990-03-20

Publications (2)

Publication Number Publication Date
CA2016841A1 CA2016841A1 (fr) 1990-11-16
CA2016841C true CA2016841C (fr) 1999-09-21

Family

ID=27582782

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2016841 Expired - Lifetime CA2016841C (fr) 1989-05-16 1990-05-15 Methode de production de polymeres ayant une activite choisie

Country Status (6)

Country Link
EP (1) EP0472638B1 (fr)
JP (1) JP3321159B2 (fr)
AU (1) AU651065B2 (fr)
CA (1) CA2016841C (fr)
PT (1) PT94066B (fr)
WO (1) WO1990014424A1 (fr)

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EP0472638A1 (fr) 1992-03-04
EP0472638A4 (en) 1992-08-19
AU651065B2 (en) 1994-07-14
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