CA2019324A1 - Comprimes de fosinopril - Google Patents
Comprimes de fosinoprilInfo
- Publication number
- CA2019324A1 CA2019324A1 CA2019324A CA2019324A CA2019324A1 CA 2019324 A1 CA2019324 A1 CA 2019324A1 CA 2019324 A CA2019324 A CA 2019324A CA 2019324 A CA2019324 A CA 2019324A CA 2019324 A1 CA2019324 A1 CA 2019324A1
- Authority
- CA
- Canada
- Prior art keywords
- tablet formulations
- fosinopril
- fosinopril tablet
- tablets
- sodium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- BIDNLKIUORFRQP-XYGFDPSESA-N (2s,4s)-4-cyclohexyl-1-[2-[[(1s)-2-methyl-1-propanoyloxypropoxy]-(4-phenylbutyl)phosphoryl]acetyl]pyrrolidine-2-carboxylic acid Chemical compound C([P@@](=O)(O[C@H](OC(=O)CC)C(C)C)CC(=O)N1[C@@H](C[C@H](C1)C1CCCCC1)C(O)=O)CCCC1=CC=CC=C1 BIDNLKIUORFRQP-XYGFDPSESA-N 0.000 title 1
- 229960002490 fosinopril Drugs 0.000 title 1
- 239000007916 tablet composition Substances 0.000 title 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 239000007884 disintegrant Substances 0.000 abstract 1
- 239000002934 diuretic Substances 0.000 abstract 1
- 230000001882 diuretic effect Effects 0.000 abstract 1
- MVPICKVDHDWCJQ-UHFFFAOYSA-N ethyl 3-pyrrolidin-1-ylpropanoate Chemical compound CCOC(=O)CCN1CCCC1 MVPICKVDHDWCJQ-UHFFFAOYSA-N 0.000 abstract 1
- 239000000945 filler Substances 0.000 abstract 1
- 229960001880 fosinopril sodium Drugs 0.000 abstract 1
- 239000008172 hydrogenated vegetable oil Substances 0.000 abstract 1
- 239000000314 lubricant Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 229940045902 sodium stearyl fumarate Drugs 0.000 abstract 1
- TVTJZMHAIQQZTL-WATAJHSMSA-M sodium;(2s,4s)-4-cyclohexyl-1-[2-[[(1s)-2-methyl-1-propanoyloxypropoxy]-(4-phenylbutyl)phosphoryl]acetyl]pyrrolidine-2-carboxylate Chemical compound [Na+].C([P@@](=O)(O[C@H](OC(=O)CC)C(C)C)CC(=O)N1[C@@H](C[C@H](C1)C1CCCCC1)C([O-])=O)CCCC1=CC=CC=C1 TVTJZMHAIQQZTL-WATAJHSMSA-M 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37768389A | 1989-07-10 | 1989-07-10 | |
| US377,683 | 1989-07-10 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2019324A1 true CA2019324A1 (fr) | 1991-01-10 |
| CA2019324C CA2019324C (fr) | 1996-08-20 |
Family
ID=23490122
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002019324A Expired - Lifetime CA2019324C (fr) | 1989-07-10 | 1990-06-19 | Comprimes de fosinopril |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0408273B1 (fr) |
| JP (1) | JP2965633B2 (fr) |
| AT (1) | ATE100321T1 (fr) |
| CA (1) | CA2019324C (fr) |
| DD (1) | DD299154A5 (fr) |
| DE (1) | DE69006125T2 (fr) |
| DK (1) | DK0408273T3 (fr) |
| ES (1) | ES2062376T3 (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9993434B2 (en) | 2003-07-31 | 2018-06-12 | Delavau L.L.C. | Calcium carbonate granulation |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2679451B1 (fr) * | 1991-07-22 | 1994-09-09 | Prographarm Laboratoires | Comprime multiparticulaire a delitement rapide. |
| US5464632C1 (en) * | 1991-07-22 | 2001-02-20 | Prographarm Lab | Rapidly disintegratable multiparticular tablet |
| ES2059260B1 (es) * | 1992-10-06 | 1995-04-16 | Espanola Prod Quimicos | Procedimiento de preparacion de comprimidos conteniendo diclofenaco; dispersables en agua. |
| FR2766089B1 (fr) * | 1997-07-21 | 2000-06-02 | Prographarm Lab | Comprime multiparticulaire perfectionne a delitement rapide |
| FR2784895B1 (fr) * | 1998-10-23 | 2004-12-17 | Gattefosse Ets Sa | Comprime a croquer a gout masque et liberation immediate du principe actif et procede de fabrication |
| CA2352430C (fr) * | 1998-12-01 | 2008-11-18 | Novo Nordisk A/S | Nouvelle composition pharmaceutique et procede de preparation |
| CA2363053C (fr) * | 2001-11-09 | 2011-01-25 | Bernard Charles Sherman | Formulation pour pastilles de bisulfate de clopidogrel |
| KR20010114199A (ko) * | 2001-12-11 | 2001-12-29 | 유형선 | 제약산업에서 사용될 수 있는 고형제제를 위한 직타용부형제의 새로운 의약품 조성물 |
| US20050095287A1 (en) * | 2003-10-29 | 2005-05-05 | Matharu Amol S. | Fosinopril composition |
| EP1819323B2 (fr) * | 2004-12-03 | 2023-03-22 | Merck Sharp & Dohme Corp. | Composition pharmaceutique renfermant un agent d'anti-nucleation |
| GR1006875B (el) * | 2005-06-30 | 2010-07-12 | "Φαρματεν" Φαρμακευτικη Βιομηχανικη Εμπορικη Α.Ε., | Βελτιωμενες φαρμακευτικες συνθεσεις περιεχουσες αναστολεις του μετατρεπτικου ενζυμου αγγειοτενσινης και μεθοδοι παρασκευης αυτων. |
| US9138414B1 (en) | 2006-09-15 | 2015-09-22 | Delavau Llc | Calcium supplement having enhanced absorption |
| SI23149A (sl) | 2009-09-21 | 2011-03-31 | Silverstone Pharma | Nove benzatinske soli ACE inhibitorjev, postopek za njihovo pripravo in njihova uporaba za zdravljenje kardiovaskularnih bolezni |
| US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4217347A (en) * | 1977-12-27 | 1980-08-12 | E. R. Squibb & Sons, Inc. | Method of treating hypertension and medicaments therefor |
| US4384123A (en) * | 1980-12-04 | 1983-05-17 | E. R. Squibb & Sons, Inc. | Phosphinylalkanoyl substituted prolines |
| US4793998A (en) * | 1986-10-20 | 1988-12-27 | Warner-Lambert Company | Stabilized drug compositions |
| CA1321753C (fr) * | 1987-04-27 | 1993-08-31 | Abraham Sudilovsky | Methode permettant d'empecher la perte des fonctions cognitives a l'aide d'un inhibiteur de l'enzyme de conversion |
-
1990
- 1990-06-19 CA CA002019324A patent/CA2019324C/fr not_active Expired - Lifetime
- 1990-07-09 ES ES90307449T patent/ES2062376T3/es not_active Expired - Lifetime
- 1990-07-09 AT AT90307449T patent/ATE100321T1/de not_active IP Right Cessation
- 1990-07-09 EP EP90307449A patent/EP0408273B1/fr not_active Expired - Lifetime
- 1990-07-09 DK DK90307449.0T patent/DK0408273T3/da active
- 1990-07-09 DE DE69006125T patent/DE69006125T2/de not_active Expired - Lifetime
- 1990-07-10 JP JP2185179A patent/JP2965633B2/ja not_active Expired - Lifetime
- 1990-10-01 DD DD90344330A patent/DD299154A5/de not_active IP Right Cessation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9993434B2 (en) | 2003-07-31 | 2018-06-12 | Delavau L.L.C. | Calcium carbonate granulation |
Also Published As
| Publication number | Publication date |
|---|---|
| EP0408273B1 (fr) | 1994-01-19 |
| JP2965633B2 (ja) | 1999-10-18 |
| DD299154A5 (de) | 1992-04-02 |
| EP0408273A1 (fr) | 1991-01-16 |
| CA2019324C (fr) | 1996-08-20 |
| DE69006125T2 (de) | 1994-05-19 |
| JPH0348623A (ja) | 1991-03-01 |
| ATE100321T1 (de) | 1994-02-15 |
| DK0408273T3 (da) | 1994-02-28 |
| DE69006125D1 (de) | 1994-03-03 |
| ES2062376T3 (es) | 1994-12-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKEX | Expiry | ||
| MKEX | Expiry |
Effective date: 20100619 |