CA2072613C - Polymeres de type iodothyronine - Google Patents

Polymeres de type iodothyronine Download PDF

Info

Publication number
CA2072613C
CA2072613C CA002072613A CA2072613A CA2072613C CA 2072613 C CA2072613 C CA 2072613C CA 002072613 A CA002072613 A CA 002072613A CA 2072613 A CA2072613 A CA 2072613A CA 2072613 C CA2072613 C CA 2072613C
Authority
CA
Canada
Prior art keywords
polymer
iodothyronine
iodo
formula
recurring units
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002072613A
Other languages
English (en)
Other versions
CA2072613A1 (fr
Inventor
Keith R. Latham
Vincent E. Latham
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shire LLC
Original Assignee
New River Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New River Pharmaceuticals Inc filed Critical New River Pharmaceuticals Inc
Publication of CA2072613A1 publication Critical patent/CA2072613A1/fr
Application granted granted Critical
Publication of CA2072613C publication Critical patent/CA2072613C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/44Two oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Polyamides (AREA)
  • Medicinal Preparation (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002072613A 1989-11-03 1990-10-31 Polymeres de type iodothyronine Expired - Lifetime CA2072613C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US43099089A 1989-11-03 1989-11-03
US430,990 1989-11-03
PCT/US1990/006213 WO1991006569A1 (fr) 1989-11-03 1990-10-31 Polymeres d'iodothyronine

Publications (2)

Publication Number Publication Date
CA2072613A1 CA2072613A1 (fr) 1991-05-04
CA2072613C true CA2072613C (fr) 2002-02-05

Family

ID=23709961

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002072613A Expired - Lifetime CA2072613C (fr) 1989-11-03 1990-10-31 Polymeres de type iodothyronine

Country Status (9)

Country Link
AU (1) AU6639790A (fr)
CA (1) CA2072613C (fr)
IE (1) IE903851A1 (fr)
IL (1) IL96226A0 (fr)
PL (1) PL287594A1 (fr)
PT (1) PT95773A (fr)
WO (1) WO1991006569A1 (fr)
YU (1) YU207990A (fr)
ZA (1) ZA908802B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1882327A (zh) 2003-11-19 2006-12-20 症变治疗公司 含磷的新的拟甲状腺素药
MX2007014502A (es) 2005-05-26 2008-02-07 Metabasis Therapeutics Inc Tiromimeticos para el tratamiento de enfermedades del higado graso.
WO2011044567A1 (fr) 2009-10-11 2011-04-14 Rutgers, The State University Of New Jersey Polymères biocompatibles pour dispositifs médicaux
US11472918B2 (en) 2012-02-03 2022-10-18 Rutgers, The State University Of New Jersey Polymeric biomaterials derived from phenolic monomers and their medical uses
CA3069030C (fr) 2012-02-03 2021-11-16 Rutgers, The State University Of New Jersey Biomateriaux polymeres derives de monomeres phenoliques et leurs utilisations a des fins medicales
AU2015370426B2 (en) 2014-12-23 2019-09-12 Rutgers, The State University Of New Jersey Biocompatible iodinated diphenol monomers and polymers
US10774030B2 (en) 2014-12-23 2020-09-15 Rutgers, The State University Of New Jersey Polymeric biomaterials derived from phenolic monomers and their medical uses
JP2020500199A (ja) 2016-11-21 2020-01-09 バイキング・セラピューティクス・インコーポレイテッド グリコーゲン蓄積症の治療方法
AU2018280118B2 (en) 2017-06-05 2021-07-15 Viking Therapeutics, Inc. Compositions for the treatment of fibrosis
ES3053674T3 (en) 2018-03-22 2026-01-23 Viking Therapeutics Inc Crystalline forms and methods of producing crystalline forms of a compound
WO2020117962A1 (fr) 2018-12-05 2020-06-11 Viking Therapeutics, Inc. Compositions pour le traitement de la fibrose et de l'inflammation
US20260049178A1 (en) * 2024-08-13 2026-02-19 Boston Scientific Scimed, Inc. Crosslinking agents and medical hydrogels formed therefrom

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2416941A1 (de) * 1974-04-08 1975-10-09 Helmut Pratzel Verfahren zur synthese von peptiden nach der n-carboxyanhydrid-methode
FR2625507B1 (fr) * 1988-01-06 1990-06-22 Delalande Sa Procede de preparation d'un copolymere de deux acides (alpha)-amines et copolymere ainsi obtenu

Also Published As

Publication number Publication date
YU207990A (sh) 1993-05-28
CA2072613A1 (fr) 1991-05-04
WO1991006569A1 (fr) 1991-05-16
PT95773A (pt) 1991-09-13
IL96226A0 (en) 1991-08-16
IE903851A1 (en) 1991-05-08
PL287594A1 (en) 1992-01-27
ZA908802B (en) 1991-06-26
AU6639790A (en) 1991-05-31

Similar Documents

Publication Publication Date Title
US5767227A (en) Iodothyronine polymers
US5910569A (en) Iodothyronine polymers
Leone-Bay et al. N-acylated. Alpha.-amino acids as novel oral delivery agents for proteins
CA2072613C (fr) Polymeres de type iodothyronine
CN1039125C (zh) 脒基苯丙氨酸衍生物的制备方法
Kopeček Reactive copolymers of N‐(2‐hydroxypropyl) methacrylamide with N‐methacryloylated derivatives of l‐leucine and l‐phenylalanine, 1. Preparation, characterization, and reactions with diamines
US3794633A (en) Process for the manufacture of peptides containing cystine
WO2004062588A2 (fr) Systeme de liberation de medicament polymerique soluble dans l'eau ciblant les os
AU613890B2 (en) 4-thiazolidinecarboxylic acid derivative, its preparation and pharmaceutical compositions containing it
WO2000053233A1 (fr) Utilisation de la conformation des proteines pour la protection et la liberation de composes chimiques
AU771188B2 (en) Use of protein conformation for the protection and release of chemical compounds
JPH0288595A (ja) 免疫刺激性ペプチド、その製法、及び該ペプチドを含有する薬剤組成物
RU2120298C1 (ru) Иммуностимулятор и препарат на его основе
RU2142958C1 (ru) Пептид, обладающий иммуномодулирующей активностью, и препарат на его основе
CA1113458A (fr) Derives de la phenylglycine
JP3893579B2 (ja) 新規なテトラペプチドおよびアンジオテンシン変換酵素阻害剤
JP2868560B2 (ja) 医薬作用を有するプリン誘導体
JPH02124861A (ja) イソポリペプチド及びその製造方法
JP2003267994A (ja) 新規なペプチドおよびアンジオテンシン変換酵素阻害剤
Lapicque et al. Polysaccharidic prodrugs for enzymatically controlled release
JPH07188283A (ja) 新規なトリペプチドおよびアンジオテンシン変換酵素 阻害剤
JP3220420B2 (ja) ペンタペプチド、その製造方法およびその用途
JP2617700B2 (ja) 細胞接着活性コア配列の繰り返し構造からなるポリペプチド
JP2003246796A (ja) 新規なワカメペプチド、l−フェニルアラニル−l−チロシンおよび血圧降下剤
AU1023599A (en) Novel pharmaceutically active compounds, their preparation and use as ece-inhibitors

Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry