CA2104372A1 - Stable salts of (+)-(1s,2r)-2-¬¬n-(2-hydroxylamino-2-oxoethyl) -n-methyl-amino|carbonyl|cyclohexane-1-carboxylic acid, pro ess for their preparation and pharmaceutical compositions containing them - Google Patents
Stable salts of (+)-(1s,2r)-2-¬¬n-(2-hydroxylamino-2-oxoethyl) -n-methyl-amino|carbonyl|cyclohexane-1-carboxylic acid, pro ess for their preparation and pharmaceutical compositions containing themInfo
- Publication number
- CA2104372A1 CA2104372A1 CA002104372A CA2104372A CA2104372A1 CA 2104372 A1 CA2104372 A1 CA 2104372A1 CA 002104372 A CA002104372 A CA 002104372A CA 2104372 A CA2104372 A CA 2104372A CA 2104372 A1 CA2104372 A1 CA 2104372A1
- Authority
- CA
- Canada
- Prior art keywords
- oxoethyl
- carbonyl
- carboxylic acid
- alkaline
- hydroxylamino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI913448A IT1252708B (it) | 1991-12-23 | 1991-12-23 | Sali stabili dell'acido (+)-(1r,2s)-2((n-(2-idrossilammino-2-ossoetil)-n-metilammino)carbonil)cicloesan-1-carbossilico,ad attivita' ace inibitrice, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono. |
| ITMI91A003448 | 1991-12-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2104372A1 true CA2104372A1 (en) | 1993-06-24 |
Family
ID=11361409
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002104372A Abandoned CA2104372A1 (en) | 1991-12-23 | 1992-12-12 | Stable salts of (+)-(1s,2r)-2-¬¬n-(2-hydroxylamino-2-oxoethyl) -n-methyl-amino|carbonyl|cyclohexane-1-carboxylic acid, pro ess for their preparation and pharmaceutical compositions containing them |
Country Status (26)
| Country | Link |
|---|---|
| EP (1) | EP0575572A1 (pt) |
| JP (1) | JPH06506002A (pt) |
| CN (1) | CN1079474A (pt) |
| AU (1) | AU657591B2 (pt) |
| BG (1) | BG98050A (pt) |
| BR (1) | BR9205652A (pt) |
| CA (1) | CA2104372A1 (pt) |
| CZ (1) | CZ379692A3 (pt) |
| EE (1) | EE9400006A (pt) |
| FI (1) | FI933685A0 (pt) |
| HR (1) | HRP921454A2 (pt) |
| HU (1) | HUT69287A (pt) |
| IT (1) | IT1252708B (pt) |
| LV (1) | LV10426B (pt) |
| MA (1) | MA22749A1 (pt) |
| MX (1) | MX9207543A (pt) |
| NZ (1) | NZ245547A (pt) |
| PL (1) | PL169086B1 (pt) |
| PT (1) | PT101156A (pt) |
| RU (1) | RU2079489C1 (pt) |
| SI (1) | SI9200409A (pt) |
| SK (1) | SK379692A3 (pt) |
| TN (1) | TNSN92117A1 (pt) |
| WO (1) | WO1993013056A1 (pt) |
| YU (1) | YU110892A (pt) |
| ZA (1) | ZA9210004B (pt) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1264860B1 (it) * | 1993-06-21 | 1996-10-17 | Guidotti & C Spa Labor | Derivati di acidi cis- e trans-2(((2-(isdrossiammino)-2-ossoetil)- alchilammino)carbonil)cicloesancarbossilici |
| US5639746A (en) * | 1994-12-29 | 1997-06-17 | The Procter & Gamble Company | Hydroxamic acid-containing inhibitors of matrix metalloproteases |
| FR2817241B1 (fr) | 2000-11-30 | 2003-03-07 | Cebal | Tube aluminium avec embout secable |
| WO2008042146A1 (en) * | 2006-09-28 | 2008-04-10 | Merck & Co., Inc. | Amine base salts of saha and polymorphs thereof |
| EP4166048B1 (en) | 2020-04-27 | 2024-12-25 | Carter-Hoffmann, LLC | Door movement system for cabinet |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1224627B (it) * | 1988-04-12 | 1990-10-04 | Guidotti & C Spa Labor | Ammidi di acidi ciclometilen_1,2_dicarbossilici adattivita' terapeutica, procedimenti per la loro preparazione e composizioni farmaceutiche che le contengono. |
-
1991
- 1991-12-23 IT ITMI913448A patent/IT1252708B/it active IP Right Grant
-
1992
- 1992-12-12 BR BR9205652A patent/BR9205652A/pt not_active Application Discontinuation
- 1992-12-12 HU HU9302389A patent/HUT69287A/hu unknown
- 1992-12-12 WO PCT/EP1992/002903 patent/WO1993013056A1/en not_active Ceased
- 1992-12-12 FI FI933685A patent/FI933685A0/fi not_active Application Discontinuation
- 1992-12-12 CA CA002104372A patent/CA2104372A1/en not_active Abandoned
- 1992-12-12 RU RU9293052414A patent/RU2079489C1/ru active
- 1992-12-12 AU AU30871/92A patent/AU657591B2/en not_active Ceased
- 1992-12-12 EP EP92924726A patent/EP0575572A1/en not_active Withdrawn
- 1992-12-12 JP JP5511398A patent/JPH06506002A/ja active Pending
- 1992-12-21 SK SK3796-92A patent/SK379692A3/sk unknown
- 1992-12-21 NZ NZ245547A patent/NZ245547A/en unknown
- 1992-12-21 CZ CS923796A patent/CZ379692A3/cs unknown
- 1992-12-22 MA MA23040A patent/MA22749A1/fr unknown
- 1992-12-22 HR HR921454A patent/HRP921454A2/hr not_active Application Discontinuation
- 1992-12-22 SI SI9200409A patent/SI9200409A/sl unknown
- 1992-12-23 YU YU110892A patent/YU110892A/sh unknown
- 1992-12-23 PL PL92297118A patent/PL169086B1/pl unknown
- 1992-12-23 TN TNTNSN92117A patent/TNSN92117A1/fr unknown
- 1992-12-23 ZA ZA9210004A patent/ZA9210004B/xx unknown
- 1992-12-23 MX MX9207543A patent/MX9207543A/es unknown
- 1992-12-23 LV LVP-92-358A patent/LV10426B/lv unknown
- 1992-12-23 PT PT101156A patent/PT101156A/pt not_active Application Discontinuation
- 1992-12-23 CN CN92113839A patent/CN1079474A/zh active Pending
-
1993
- 1993-08-18 BG BG98050A patent/BG98050A/bg unknown
-
1994
- 1994-05-23 EE EE9400006A patent/EE9400006A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1079474A (zh) | 1993-12-15 |
| HUT69287A (en) | 1995-09-28 |
| HU9302389D0 (en) | 1993-11-29 |
| PL169086B1 (pl) | 1996-05-31 |
| HRP921454A2 (en) | 1995-02-28 |
| AU657591B2 (en) | 1995-03-16 |
| ITMI913448A1 (it) | 1993-06-23 |
| IT1252708B (it) | 1995-06-26 |
| YU110892A (sh) | 1996-01-08 |
| AU3087192A (en) | 1993-07-28 |
| FI933685A7 (fi) | 1993-08-20 |
| PL297118A1 (en) | 1993-09-06 |
| RU2079489C1 (ru) | 1997-05-20 |
| LV10426B (en) | 1995-08-20 |
| FI933685L (fi) | 1993-08-20 |
| NZ245547A (en) | 1995-12-21 |
| CZ379692A3 (en) | 1993-09-15 |
| SI9200409A (en) | 1993-09-30 |
| JPH06506002A (ja) | 1994-07-07 |
| ITMI913448A0 (it) | 1991-12-23 |
| MX9207543A (es) | 1993-08-01 |
| SK379692A3 (en) | 1995-04-12 |
| PT101156A (pt) | 1994-06-30 |
| TNSN92117A1 (fr) | 1993-06-08 |
| MA22749A1 (fr) | 1993-07-01 |
| FI933685A0 (fi) | 1993-08-20 |
| BG98050A (bg) | 1994-04-29 |
| EE9400006A (et) | 1995-12-15 |
| WO1993013056A1 (en) | 1993-07-08 |
| ZA9210004B (en) | 1993-12-13 |
| LV10426A (lv) | 1995-02-20 |
| EP0575572A1 (en) | 1993-12-29 |
| BR9205652A (pt) | 1994-05-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US7790743B2 (en) | Modulators of cellular adhesion | |
| KR100388747B1 (ko) | 인돌유도체 | |
| JPH02104526A (ja) | 高血圧症治療用組成物 | |
| JP2001502296A (ja) | ニューロペプチド―ｙリガンド | |
| NZ222825A (en) | Pyridazodiazepine derivatives and pharmaceutical compositions | |
| IE841782L (en) | Peptides | |
| CA2104372A1 (en) | Stable salts of (+)-(1s,2r)-2-¬¬n-(2-hydroxylamino-2-oxoethyl) -n-methyl-amino|carbonyl|cyclohexane-1-carboxylic acid, pro ess for their preparation and pharmaceutical compositions containing them | |
| US4134991A (en) | Derivatives of 2-(3-phenyl-2-aminopropionyloxy)-acetic acid | |
| SI21236A (sl) | Postopek kristalizacije losartan kalija | |
| US4734501A (en) | N-alkylation of dihydrolysergic acid | |
| US4914222A (en) | Crystalline salts of L or (S)-3-(3,4-dihydroxyphenyl)-2-methylalanine esters and process | |
| EP0134582A2 (en) | Novel peptides and process for preparing the same and pharmaceutical composition | |
| US4490386A (en) | Phosphate salts of 1-[2-[(1-alkoxycarbonyl-3-aralkyl)-amino]-1-oxoalkyl]octahydro-1H-indole-2-carboxylic acids, preparation of, and medical compositions thereof | |
| EP0193965A2 (en) | Novel guanidinomethylcyclohexancarboxylic acid compounds, processes for preparing them, and pharmaceutical compositions containing them | |
| KR880002594B1 (ko) | 트리펲타이드를 함유한 n-카르복시알킬프롤린을 제조하는 방법 | |
| CA1199638A (en) | Eburnane-oxime ethers, process for their preparation and pharmaceutical compositions containing them | |
| WO1995004043A1 (en) | Optical resolution of gamma-(4-(((1,1-dimethylethoxy)carbonyl)methylamino)-piperidinyl-1)-gamma-oxo-alpha-(phenylmethyl)-butynic acid with (n,s-)cyclohexyl ethylamine | |
| EP0170549B1 (fr) | Dérivés de tétrahydro-4,5,6,7 furo ou 1H-pyrrolo[2,3-c]pyridine, leur préparation et leur application en therapeutique | |
| US4113877A (en) | Substituted 2-aminomethylphenyl sulfamates | |
| US5099022A (en) | Process for purification of 1,2-bis(nicotinamido)propane | |
| EP0213571A2 (de) | 3-Aminomethylpyrrol-1-yl-alkylamine und diese Verbindungen enthaltende therapeutische Mittel | |
| EP0101633A1 (en) | Pyridinecarboxylic esters of dopamine and of its N-alkyl derivatives | |
| RU2109742C1 (ru) | Гидроксиламины и способ их получения | |
| EP0333073A2 (en) | N-cycloalkylaminoethylbenzamide derivatives, their synthesis and pharmaceutical preparations | |
| MC1146A1 (fr) | Derives peptidiques et procede pour leur preparation |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |