CA2175202A1 - Procede de stabilisation de la proteine c ou de la proteine c activee et composition stabilisante obtenue par ce procede - Google Patents

Procede de stabilisation de la proteine c ou de la proteine c activee et composition stabilisante obtenue par ce procede

Info

Publication number
CA2175202A1
CA2175202A1 CA002175202A CA2175202A CA2175202A1 CA 2175202 A1 CA2175202 A1 CA 2175202A1 CA 002175202 A CA002175202 A CA 002175202A CA 2175202 A CA2175202 A CA 2175202A CA 2175202 A1 CA2175202 A1 CA 2175202A1
Authority
CA
Canada
Prior art keywords
protein
composition obtained
stabilizing
activated protein
stabilized composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002175202A
Other languages
English (en)
Other versions
CA2175202C (fr
Inventor
Kazumasa Miyata
Yoshinori Akimoto
Yoichi Ogata
Tomohiro Nakagaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chemo Sero Therapeutic Research Institute Kaketsuken
Teijin Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP5292500A external-priority patent/JP2886061B2/ja
Application filed by Individual filed Critical Individual
Publication of CA2175202A1 publication Critical patent/CA2175202A1/fr
Application granted granted Critical
Publication of CA2175202C publication Critical patent/CA2175202C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6464—Protein C (3.4.21.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4866—Protein C (3.4.21.69)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
CA002175202A 1993-10-29 1994-10-27 Procede de stabilisation de la proteine c ou de la proteine c activee et composition stabilisante obtenue par ce procede Expired - Lifetime CA2175202C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP292500/1993 1993-10-29
JP5292500A JP2886061B2 (ja) 1993-10-29 1993-10-29 プロテインｃもしくは活性化プロテインｃの安定化方法及び安定化組成物
PCT/JP1994/001804 WO1995011698A1 (fr) 1993-10-29 1994-10-27 PROCEDE DE STABILISATION DE PROTéINE C ACTIVEE OU NON ACTIVEE ET COMPOSITION STABILISEE

Publications (2)

Publication Number Publication Date
CA2175202A1 true CA2175202A1 (fr) 1995-05-04
CA2175202C CA2175202C (fr) 2006-09-19

Family

ID=37056965

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002175202A Expired - Lifetime CA2175202C (fr) 1993-10-29 1994-10-27 Procede de stabilisation de la proteine c ou de la proteine c activee et composition stabilisante obtenue par ce procede

Country Status (1)

Country Link
CA (1) CA2175202C (fr)

Also Published As

Publication number Publication date
CA2175202C (fr) 2006-09-19

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Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20141027