CA2205351A1 - Administration de medicament a liberation prolongee comprenant une gomme hydrocolloide en poudre obtenue a partir de spermatophytes - Google Patents

Administration de medicament a liberation prolongee comprenant une gomme hydrocolloide en poudre obtenue a partir de spermatophytes

Info

Publication number
CA2205351A1
CA2205351A1 CA002205351A CA2205351A CA2205351A1 CA 2205351 A1 CA2205351 A1 CA 2205351A1 CA 002205351 A CA002205351 A CA 002205351A CA 2205351 A CA2205351 A CA 2205351A CA 2205351 A1 CA2205351 A1 CA 2205351A1
Authority
CA
Canada
Prior art keywords
drug
gum
composition
excipient
hydrocolloid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002205351A
Other languages
English (en)
Inventor
Jagdish Parasrampuria
Eric H. Kuhrts
David R. Friend
Karen Yu
Syed A. Altaf
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Venture Banking Group
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2205351A1 publication Critical patent/CA2205351A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)

Abstract

Une composition pharmaceutique à administration orale permet d'obtenir la libération prolongée d'un médicament chez un mammifère. La composition comprend (a) une quantité appropriée d'une gomme hydrocolloïde pharmaceutiquement acceptable pouvant être obtenue à partir de spermatophytes (p.ex., entre environ 20 % et 90 % en poids), (b) un autre excipient (p.ex., entre environ 5 % et environ 30 % en poids) qui facilite la libération prolongée et (c) une quantité thérapeutiquement efficace d'un médicament. De préférence, la granulométrie moyenne de la gomme est inférieure ou environ égale à 150 µ. L'invention se rapporte également à un procédé de préparation de la composition et à un procédé permettant d'obtenir une libération prolongée d'un médicament en administrant la composition à un patient nécessitant d'être traité à l'aide de celle-ci.
CA002205351A 1994-12-01 1995-11-30 Administration de medicament a liberation prolongee comprenant une gomme hydrocolloide en poudre obtenue a partir de spermatophytes Abandoned CA2205351A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34851594A 1994-12-01 1994-12-01
US08/348,515 1994-12-01

Publications (1)

Publication Number Publication Date
CA2205351A1 true CA2205351A1 (fr) 1996-06-06

Family

ID=23368363

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002205351A Abandoned CA2205351A1 (fr) 1994-12-01 1995-11-30 Administration de medicament a liberation prolongee comprenant une gomme hydrocolloide en poudre obtenue a partir de spermatophytes

Country Status (9)

Country Link
EP (1) EP0793485A4 (fr)
JP (1) JPH10509981A (fr)
CN (1) CN1172429A (fr)
AU (1) AU709413B2 (fr)
CA (1) CA2205351A1 (fr)
FI (1) FI972304A7 (fr)
MX (1) MX9704043A (fr)
NO (1) NO972486L (fr)
WO (1) WO1996016638A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5811388A (en) * 1995-06-07 1998-09-22 Cibus Pharmaceutical, Inc. Delivery of drugs to the lower GI tract
IL119627A (en) * 1996-11-17 2002-03-10 Yissum Res Dev Co PHARMACEUTICAL PREPARATIONS FOR THE CONTROLLED-RELEASE OF AN ACTIVE AGENT COMPRISING AT LEAST ONE β-LACTAM ANTIBIOTIC AGENT
US6210710B1 (en) * 1997-04-28 2001-04-03 Hercules Incorporated Sustained release polymer blend for pharmaceutical applications
EP0974343B1 (fr) * 1998-07-22 2004-09-29 Pharma Pass II LLC Procédé de préparation d'une composition solide contentant du metoprolol
EP0987020A1 (fr) * 1998-09-04 2000-03-22 Pharma Pass LLC Composition contenant du metoprolol et procédé de préparation
SE0003125D0 (sv) * 2000-09-05 2000-09-05 Astrazeneca Ab Modified polymers

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1327938A (en) * 1969-12-17 1973-08-22 Sucrest Corp Composition for use in forming tablets
DE2130545A1 (de) * 1971-06-19 1972-12-21 Merck Patent Gmbh Pharmazeutischer Formkoerper
CH630257A5 (en) * 1975-03-17 1982-06-15 Hoffmann La Roche Sustained release formulation
DK130287D0 (da) * 1987-03-13 1987-03-13 Benzon As Alfred Oralt praeparat
US5169639A (en) * 1988-09-19 1992-12-08 Edward Mendell Co., Inc. Controlled release verapamil tablets
AU5745394A (en) * 1992-12-30 1994-08-15 Fmc Corporation Readily available konjac glucomannan sustained release excipient

Also Published As

Publication number Publication date
AU4372096A (en) 1996-06-19
WO1996016638A1 (fr) 1996-06-06
AU709413B2 (en) 1999-08-26
MX9704043A (es) 1998-02-28
FI972304L (fi) 1997-05-30
FI972304A0 (fi) 1997-05-30
EP0793485A1 (fr) 1997-09-10
EP0793485A4 (fr) 1998-08-26
CN1172429A (zh) 1998-02-04
FI972304A7 (fi) 1997-05-30
JPH10509981A (ja) 1998-09-29
NO972486L (no) 1997-07-31
NO972486D0 (no) 1997-05-30

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Legal Events

Date Code Title Description
FZDE Discontinued