NO972486L - Vedvarende frigjöring av legemiddel ved anvendelse av en pulverisert hydrokolloid-gummi som kan oppnås fra höyere planter - Google Patents

Vedvarende frigjöring av legemiddel ved anvendelse av en pulverisert hydrokolloid-gummi som kan oppnås fra höyere planter

Info

Publication number
NO972486L
NO972486L NO972486A NO972486A NO972486L NO 972486 L NO972486 L NO 972486L NO 972486 A NO972486 A NO 972486A NO 972486 A NO972486 A NO 972486A NO 972486 L NO972486 L NO 972486L
Authority
NO
Norway
Prior art keywords
higher plants
drug release
hydrocolloid gum
drug
composition
Prior art date
Application number
NO972486A
Other languages
English (en)
Other versions
NO972486D0 (no
Inventor
Eric H Kuhrts
David R Friend
Syed A Altaf
Karen Yu
Jagdish Parasrampuria
Original Assignee
Cibus Pharmaceutical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cibus Pharmaceutical Inc filed Critical Cibus Pharmaceutical Inc
Publication of NO972486D0 publication Critical patent/NO972486D0/no
Publication of NO972486L publication Critical patent/NO972486L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)

Abstract

En farmasøytisk sammensetning som tilføres gjennom munnen for å oppnå vedvarende frigjøring av et legemiddel i et pattedyr. Sammensetningen omfatter (a) en egnet mengde av en farmasøytisk godtagbar hydrokolloid-gummi som kan oppnås fra høyere planter (f eks. omkring 20% til 90 vekt%), (b) en annen eksipient (f eks. omkring 5% til 30 vekt%) som bidrar til vedvarende frigjøring og (c) en terapeutisk effektiv mengde av et legemiddel. Det er foretrukket at gjermomsninlig panikkelstorrelse av gummien er omkring 150 \x eller mindre. Omfattet er også en fremgangsmåte for å fremstille sammensetningen og en metode for å oppnå vedvarende frigjoring av et legemiddel ved å tilfore sammensetningen til et tilfelle som har behov for dene.
NO972486A 1994-12-01 1997-05-30 Vedvarende frigjöring av legemiddel ved anvendelse av en pulverisert hydrokolloid-gummi som kan oppnås fra höyere planter NO972486L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34851594A 1994-12-01 1994-12-01
PCT/US1995/015593 WO1996016638A1 (en) 1994-12-01 1995-11-30 Sustained-release drug delivery employing a powdered hydrocolloid gum obtainable from higher plants

Publications (2)

Publication Number Publication Date
NO972486D0 NO972486D0 (no) 1997-05-30
NO972486L true NO972486L (no) 1997-07-31

Family

ID=23368363

Family Applications (1)

Application Number Title Priority Date Filing Date
NO972486A NO972486L (no) 1994-12-01 1997-05-30 Vedvarende frigjöring av legemiddel ved anvendelse av en pulverisert hydrokolloid-gummi som kan oppnås fra höyere planter

Country Status (9)

Country Link
EP (1) EP0793485A4 (no)
JP (1) JPH10509981A (no)
CN (1) CN1172429A (no)
AU (1) AU709413B2 (no)
CA (1) CA2205351A1 (no)
FI (1) FI972304A0 (no)
MX (1) MX9704043A (no)
NO (1) NO972486L (no)
WO (1) WO1996016638A1 (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5811388A (en) * 1995-06-07 1998-09-22 Cibus Pharmaceutical, Inc. Delivery of drugs to the lower GI tract
IL119627A (en) * 1996-11-17 2002-03-10 Yissum Res Dev Co PHARMACEUTICAL PREPARATIONS FOR THE CONTROLLED-RELEASE OF AN ACTIVE AGENT COMPRISING AT LEAST ONE β-LACTAM ANTIBIOTIC AGENT
US6210710B1 (en) * 1997-04-28 2001-04-03 Hercules Incorporated Sustained release polymer blend for pharmaceutical applications
EP0987020A1 (en) * 1998-09-04 2000-03-22 Pharma Pass LLC Metoprolol composition and processes for manufacturing the same
EP0974343B1 (en) * 1998-07-22 2004-09-29 Pharma Pass II LLC Process for manufacturing a solid metoprolol composition
SE0003125D0 (sv) * 2000-09-05 2000-09-05 Astrazeneca Ab Modified polymers

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1327938A (en) * 1969-12-17 1973-08-22 Sucrest Corp Composition for use in forming tablets
DE2130545A1 (de) * 1971-06-19 1972-12-21 Merck Patent Gmbh Pharmazeutischer Formkoerper
CH630257A5 (en) * 1975-03-17 1982-06-15 Hoffmann La Roche Sustained release formulation
DK130287D0 (da) * 1987-03-13 1987-03-13 Benzon As Alfred Oralt praeparat
US5169639A (en) * 1988-09-19 1992-12-08 Edward Mendell Co., Inc. Controlled release verapamil tablets
EP0676967A4 (en) * 1992-12-30 1996-10-02 Fmc Corp RELEASED, EXTENDED, EASY TO PRODUCE EXCIPIENT, BASED ON KONJAC GLUCOMANNANE.

Also Published As

Publication number Publication date
FI972304A7 (fi) 1997-05-30
MX9704043A (es) 1998-02-28
CA2205351A1 (en) 1996-06-06
AU709413B2 (en) 1999-08-26
EP0793485A1 (en) 1997-09-10
JPH10509981A (ja) 1998-09-29
EP0793485A4 (en) 1998-08-26
NO972486D0 (no) 1997-05-30
CN1172429A (zh) 1998-02-04
FI972304L (fi) 1997-05-30
FI972304A0 (fi) 1997-05-30
WO1996016638A1 (en) 1996-06-06
AU4372096A (en) 1996-06-19

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