CA2277366A1 - Systeme therapeutique transdermique contenant de l'acide acetylsalicylique a resorption renforcee - Google Patents

Systeme therapeutique transdermique contenant de l'acide acetylsalicylique a resorption renforcee Download PDF

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Publication number
CA2277366A1
CA2277366A1 CA002277366A CA2277366A CA2277366A1 CA 2277366 A1 CA2277366 A1 CA 2277366A1 CA 002277366 A CA002277366 A CA 002277366A CA 2277366 A CA2277366 A CA 2277366A CA 2277366 A1 CA2277366 A1 CA 2277366A1
Authority
CA
Canada
Prior art keywords
limonene
acetylsalicylic acid
therapeutic system
dimethylisosorbide
transdermal therapeutic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002277366A
Other languages
English (en)
Inventor
Michael Horstmann
Gerd Hoffmann
Heinrich Kindel
Theresa Maria Murphy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LTS Lohmann Therapie Systeme AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2277366A1 publication Critical patent/CA2277366A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Ce système thérapeutique transdermique contenant de l'acide acétylsalicylique comprend une couche de fond sensiblement imperméable au principe actif et à l'humidité, un réservoir de principe actif et le cas échéant une couche de protection détachable. Ce système thérapeutique transdermique se caractérise en ce qu'il contient du limonène et de l'isosorbide de diméthyle dans un rapport égal à au moins 50 g de limonène par 50 g d'isosorbide de diméthyle dans la zone du principe actif.
CA002277366A 1997-01-15 1998-01-03 Systeme therapeutique transdermique contenant de l'acide acetylsalicylique a resorption renforcee Abandoned CA2277366A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19701059.8 1997-01-15
DE19701059A DE19701059C2 (de) 1997-01-15 1997-01-15 Acetylsalicylsäure enthaltendes transdermales therapeutisches System mit Resorptionsverstärkung
PCT/EP1998/000013 WO1998031348A1 (fr) 1997-01-15 1998-01-03 Systeme therapeutique transdermique contenant de l'acide acetylsalicylique a resorption renforcee

Publications (1)

Publication Number Publication Date
CA2277366A1 true CA2277366A1 (fr) 1998-07-23

Family

ID=7817375

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002277366A Abandoned CA2277366A1 (fr) 1997-01-15 1998-01-03 Systeme therapeutique transdermique contenant de l'acide acetylsalicylique a resorption renforcee

Country Status (8)

Country Link
EP (1) EP1023053A1 (fr)
JP (1) JP2001508069A (fr)
KR (1) KR20000070228A (fr)
AU (1) AU726094B2 (fr)
CA (1) CA2277366A1 (fr)
DE (1) DE19701059C2 (fr)
NO (1) NO993435D0 (fr)
WO (1) WO1998031348A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19949202A1 (de) * 1999-10-13 2001-05-03 Lohmann Therapie Syst Lts Transdermales therapeutisches System zur Abgabe von Acetylsalicylsäure und/oder Salicylsäure
DE19949252B4 (de) * 1999-10-13 2004-02-12 Lts Lohmann Therapie-Systeme Ag Verwendung eines superfiziellen therapeutischen Systems zur topischen Applikation von Acetylsalicylsäure zur Behandlung von Akne-Erkrankungen und Verfahren zu seiner Herstellung
DE19959913A1 (de) * 1999-12-11 2001-06-28 Lohmann Therapie Syst Lts Acetylsalicylsäure enthaltendes transdermales System zur Behandlung von Migräne
KR100448469B1 (ko) * 2001-10-26 2004-09-13 신풍제약주식회사 항염증제의 경피 조성물 및 장치
KR100951750B1 (ko) 2001-11-01 2010-04-09 노바르티스 아게 분무 건조 방법 및 그 조성물
DE10338162B3 (de) † 2003-08-20 2005-06-02 Haldex Brake Products Gmbh Verfahren zum Betreiben einer Druckluftbeschaffungsanlage eines Kraftfahrzeuges sowie Druckluftaufbereitungseinrichtung
DE102005033543A1 (de) * 2005-07-14 2007-01-18 Grünenthal GmbH Ein einen Duftstoff aufweisendes transdermales therapeutisches System
DE102005050431A1 (de) * 2005-10-21 2007-04-26 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System zur Verabreicherung lipophiler und/oder wenig hautpermeabler Wirkstoffe
IT202000014578A1 (it) * 2020-06-18 2021-12-18 Poli Md S R L Dispositivo medicale comprendente acido acetil salicilico

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4228162A (en) * 1979-07-09 1980-10-14 Research Corporation Dimethyl isosorbide in liquid formulation of aspirin
US5164416A (en) * 1989-02-03 1992-11-17 Lintec Corporation Transdermal therapeutic formulation containing a limonene
DE4332094C2 (de) * 1993-09-22 1995-09-07 Lohmann Therapie Syst Lts Lösemittelfrei herstellbares Wirkstoffpflaster und Verfahren zu seiner Herstellung
DE4332093C2 (de) * 1993-09-22 1995-07-13 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit dem Wirkstoff Acetylsalicylsäure und Verfahren zu seiner Herstellung

Also Published As

Publication number Publication date
JP2001508069A (ja) 2001-06-19
DE19701059C2 (de) 2000-12-21
WO1998031348A1 (fr) 1998-07-23
AU726094B2 (en) 2000-11-02
NO993435L (no) 1999-07-12
NO993435D0 (no) 1999-07-12
DE19701059A1 (de) 1998-07-16
EP1023053A1 (fr) 2000-08-02
KR20000070228A (ko) 2000-11-25
AU5986298A (en) 1998-08-07

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued
FZDE Discontinued

Effective date: 20030103