CA2304000A1 - Antagoniste du recepteur de la vitronectine - Google Patents
Antagoniste du recepteur de la vitronectine Download PDFInfo
- Publication number
- CA2304000A1 CA2304000A1 CA002304000A CA2304000A CA2304000A1 CA 2304000 A1 CA2304000 A1 CA 2304000A1 CA 002304000 A CA002304000 A CA 002304000A CA 2304000 A CA2304000 A CA 2304000A CA 2304000 A1 CA2304000 A1 CA 2304000A1
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- CA
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- Prior art keywords
- compound
- cells
- compound according
- medicament
- manufacture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
L'invention porte sur un composé de formule (I) qui est un antagoniste du récepteur de la vitronectine et qui est utile dans le traitement de l'ostéoporose, ou sur un sel de celui-ci, acceptable en pharmacie.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5986797P | 1997-09-24 | 1997-09-24 | |
| US60/059,867 | 1997-09-24 | ||
| PCT/US1998/019987 WO1999015178A1 (fr) | 1997-09-24 | 1998-09-24 | Antagoniste du recepteur de la vitronectine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2304000A1 true CA2304000A1 (fr) | 1999-04-01 |
Family
ID=22025805
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002304000A Abandoned CA2304000A1 (fr) | 1997-09-24 | 1998-09-24 | Antagoniste du recepteur de la vitronectine |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP1023073A1 (fr) |
| JP (1) | JP2002500162A (fr) |
| KR (1) | KR20010024249A (fr) |
| CN (1) | CN1271284A (fr) |
| AU (1) | AU9578798A (fr) |
| BR (1) | BR9813214A (fr) |
| CA (1) | CA2304000A1 (fr) |
| HU (1) | HUP0003931A2 (fr) |
| IL (1) | IL135188A0 (fr) |
| NO (1) | NO20001515L (fr) |
| PL (1) | PL339414A1 (fr) |
| TR (1) | TR200000786T2 (fr) |
| WO (1) | WO1999015178A1 (fr) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU747503B2 (en) | 1999-02-03 | 2002-05-16 | Merck & Co., Inc. | Benzazepine derivatives as alpha-V integrin receptor antagonists |
| US6514964B1 (en) | 1999-09-27 | 2003-02-04 | Amgen Inc. | Fused cycloheptane and fused azacycloheptane compounds and their methods of use |
| EP1381384B1 (fr) | 2001-04-24 | 2011-05-25 | Merck Patent GmbH | POLYTHERAPIE A BASE D'AGENTS ANTIANGIOGENIQUES ET DE FACTEUR DE NECROSE TUMORALE TNFalpha |
| KR20040058229A (ko) | 2001-10-22 | 2004-07-03 | 더 스크립스 리서치 인스티튜트 | 항체 표적화 화합물 |
| JP2006522139A (ja) * | 2003-04-04 | 2006-09-28 | スミスクライン・ビーチャム・コーポレイション | ベンズアゼピンの製造方法およびその中間体 |
| AU2005210493B2 (en) | 2004-02-02 | 2009-06-04 | Pioneer Hi-Bred International, Inc. | AP2 domain transcription factor ODP2 (ovule development protein 2) and methods of use |
| UA87854C2 (en) | 2004-06-07 | 2009-08-25 | Мерк Энд Ко., Инк. | N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators |
| EP1973569B1 (fr) | 2006-01-18 | 2013-05-22 | Merck Patent GmbH | Traitement specifique utilisant des ligands de integrine destine a traiter un cancer |
| JP2010516645A (ja) | 2007-01-18 | 2010-05-20 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | 癌を治療するためのインテグリンリガンドを用いる特異的療法および薬剤 |
| CA2705916C (fr) | 2007-11-16 | 2016-01-05 | Ube Industries, Ltd. | Compose de benzazepinone |
| WO2009111679A2 (fr) * | 2008-03-06 | 2009-09-11 | Smithkline Beecham Corporation | Procédé |
| US8518927B2 (en) | 2009-02-10 | 2013-08-27 | The Scripps Research Institute | Chemically programmed vaccination |
| EP2415474B1 (fr) | 2009-03-30 | 2013-08-28 | Ube Industries, Ltd. | Composition pharmaceutique pour la prévention ou le traitement de maladies ophtalmiques |
| US20120130146A1 (en) | 2009-05-25 | 2012-05-24 | Merck Patent Gmbh | Continuous administration of cilengitide in cancer treatments |
| AU2010339481B2 (en) | 2009-12-30 | 2016-02-04 | Pioneer Hi-Bred International, Inc. | Methods and compositions for targeted polynucleotide modification |
| EP3078748B1 (fr) | 2009-12-30 | 2021-08-11 | Pioneer Hi-Bred International, Inc. | Procédés et compositions pour l'introduction et l'expression régulée de gènes dans des plantes |
| ES2864079T3 (es) | 2014-05-30 | 2021-10-13 | Pfizer | Derivados de carbonitrilo como moduladores selectivos del receptor de andrógenos |
| WO2023275715A1 (fr) | 2021-06-30 | 2023-01-05 | Pfizer Inc. | Métabolites de modulateurs sélectifs du récepteur des androgènes |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA60311C2 (uk) * | 1996-10-02 | 2003-10-15 | Смітклайн Бічам Корпорейшн | Антагоністи рецептора вітронектину, спосіб одержання цих сполук та фармацевтична композиція |
-
1998
- 1998-09-24 BR BR9813214-8A patent/BR9813214A/pt not_active Application Discontinuation
- 1998-09-24 KR KR1020007003093A patent/KR20010024249A/ko not_active Withdrawn
- 1998-09-24 PL PL98339414A patent/PL339414A1/xx unknown
- 1998-09-24 CA CA002304000A patent/CA2304000A1/fr not_active Abandoned
- 1998-09-24 EP EP98949471A patent/EP1023073A1/fr active Pending
- 1998-09-24 AU AU95787/98A patent/AU9578798A/en not_active Abandoned
- 1998-09-24 CN CN98809494A patent/CN1271284A/zh active Pending
- 1998-09-24 IL IL13518898A patent/IL135188A0/xx unknown
- 1998-09-24 HU HU0003931A patent/HUP0003931A2/hu unknown
- 1998-09-24 JP JP2000512547A patent/JP2002500162A/ja not_active Withdrawn
- 1998-09-24 WO PCT/US1998/019987 patent/WO1999015178A1/fr not_active Ceased
- 1998-09-24 TR TR2000/00786T patent/TR200000786T2/xx unknown
-
2000
- 2000-03-23 NO NO20001515A patent/NO20001515L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU9578798A (en) | 1999-04-12 |
| TR200000786T2 (tr) | 2000-08-21 |
| IL135188A0 (en) | 2001-05-20 |
| NO20001515D0 (no) | 2000-03-23 |
| EP1023073A1 (fr) | 2000-08-02 |
| HUP0003931A2 (hu) | 2001-10-28 |
| BR9813214A (pt) | 2000-08-29 |
| PL339414A1 (en) | 2000-12-18 |
| JP2002500162A (ja) | 2002-01-08 |
| CN1271284A (zh) | 2000-10-25 |
| KR20010024249A (ko) | 2001-03-26 |
| WO1999015178A1 (fr) | 1999-04-01 |
| NO20001515L (no) | 2000-03-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |