JP2002500162A - ビトロネクチン受容体アンタゴニスト - Google Patents

ビトロネクチン受容体アンタゴニスト

Info

Publication number: JP2002500162A
Authority: JP; Japan
Prior art keywords: compound; compound according; cells; medicament; manufacture
Prior art date: 1997-09-24
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

JP2000512547A

Other languages

English (en)

Japanese (ja)

Inventor

ウィリアム・イー・ボンディネル

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

SmithKline Beecham Corp

Original Assignee

SmithKline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-09-24

Filing date

1998-09-24

Publication date

2002-01-08

1998-09-24 Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp

2002-01-08 Publication of JP2002500162A publication Critical patent/JP2002500162A/ja

Status Withdrawn legal-status Critical Current

Links

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Classifications

- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Orthopedic Medicine & Surgery (AREA)
Oncology (AREA)
Pain & Pain Management (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Plural Heterocyclic Compounds (AREA)

JP2000512547A 1997-09-24 1998-09-24 ビトロネクチン受容体アンタゴニスト Withdrawn JP2002500162A (ja)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US5986797P	1997-09-24	1997-09-24
US60/059,867		1997-09-24
PCT/US1998/019987 WO1999015178A1 (fr)	1997-09-24	1998-09-24	Antagoniste du recepteur de la vitronectine

Publications (1)

Publication Number	Publication Date
JP2002500162A true JP2002500162A (ja)	2002-01-08

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ID=22025805

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP2000512547A Withdrawn JP2002500162A (ja)	1997-09-24	1998-09-24	ビトロネクチン受容体アンタゴニスト

Country Status (13)

Country	Link
EP (1)	EP1023073A1 (fr)
JP (1)	JP2002500162A (fr)
KR (1)	KR20010024249A (fr)
CN (1)	CN1271284A (fr)
AU (1)	AU9578798A (fr)
BR (1)	BR9813214A (fr)
CA (1)	CA2304000A1 (fr)
HU (1)	HUP0003931A2 (fr)
IL (1)	IL135188A0 (fr)
NO (1)	NO20001515L (fr)
PL (1)	PL339414A1 (fr)
TR (1)	TR200000786T2 (fr)
WO (1)	WO1999015178A1 (fr)

Families Citing this family (18)

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Publication number	Priority date	Publication date	Assignee	Title
AU747503B2 (en)	1999-02-03	2002-05-16	Merck & Co., Inc.	Benzazepine derivatives as alpha-V integrin receptor antagonists
US6514964B1 (en)	1999-09-27	2003-02-04	Amgen Inc.	Fused cycloheptane and fused azacycloheptane compounds and their methods of use
EP1381384B1 (fr)	2001-04-24	2011-05-25	Merck Patent GmbH	POLYTHERAPIE A BASE D'AGENTS ANTIANGIOGENIQUES ET DE FACTEUR DE NECROSE TUMORALE TNFalpha
KR20040058229A (ko)	2001-10-22	2004-07-03	더 스크립스 리서치 인스티튜트	항체 표적화 화합물
JP2006522139A (ja) *	2003-04-04	2006-09-28	スミスクライン・ビーチャム・コーポレイション	ベンズアゼピンの製造方法およびその中間体
AU2005210493B2 (en)	2004-02-02	2009-06-04	Pioneer Hi-Bred International, Inc.	AP2 domain transcription factor ODP2 (ovule development protein 2) and methods of use
UA87854C2 (en)	2004-06-07	2009-08-25	Мерк Энд Ко., Инк.	N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators
EP1973569B1 (fr)	2006-01-18	2013-05-22	Merck Patent GmbH	Traitement specifique utilisant des ligands de integrine destine a traiter un cancer
JP2010516645A (ja)	2007-01-18	2010-05-20	メルクパテントゲゼルシャフトミットベシュレンクテルハフツング	癌を治療するためのインテグリンリガンドを用いる特異的療法および薬剤
CA2705916C (fr)	2007-11-16	2016-01-05	Ube Industries, Ltd.	Compose de benzazepinone
WO2009111679A2 (fr) *	2008-03-06	2009-09-11	Smithkline Beecham Corporation	Procédé
US8518927B2 (en)	2009-02-10	2013-08-27	The Scripps Research Institute	Chemically programmed vaccination
EP2415474B1 (fr)	2009-03-30	2013-08-28	Ube Industries, Ltd.	Composition pharmaceutique pour la prévention ou le traitement de maladies ophtalmiques
US20120130146A1 (en)	2009-05-25	2012-05-24	Merck Patent Gmbh	Continuous administration of cilengitide in cancer treatments
AU2010339481B2 (en)	2009-12-30	2016-02-04	Pioneer Hi-Bred International, Inc.	Methods and compositions for targeted polynucleotide modification
EP3078748B1 (fr)	2009-12-30	2021-08-11	Pioneer Hi-Bred International, Inc.	Procédés et compositions pour l'introduction et l'expression régulée de gènes dans des plantes
ES2864079T3 (es)	2014-05-30	2021-10-13	Pfizer	Derivados de carbonitrilo como moduladores selectivos del receptor de andrógenos
WO2023275715A1 (fr)	2021-06-30	2023-01-05	Pfizer Inc.	Métabolites de modulateurs sélectifs du récepteur des androgènes

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Publication number	Priority date	Publication date	Assignee	Title
UA60311C2 (uk) *	1996-10-02	2003-10-15	Смітклайн Бічам Корпорейшн	Антагоністи рецептора вітронектину, спосіб одержання цих сполук та фармацевтична композиція

1998
- 1998-09-24 BR BR9813214-8A patent/BR9813214A/pt not_active Application Discontinuation
- 1998-09-24 KR KR1020007003093A patent/KR20010024249A/ko not_active Withdrawn
- 1998-09-24 PL PL98339414A patent/PL339414A1/xx unknown
- 1998-09-24 CA CA002304000A patent/CA2304000A1/fr not_active Abandoned
- 1998-09-24 EP EP98949471A patent/EP1023073A1/fr active Pending
- 1998-09-24 AU AU95787/98A patent/AU9578798A/en not_active Abandoned
- 1998-09-24 CN CN98809494A patent/CN1271284A/zh active Pending
- 1998-09-24 IL IL13518898A patent/IL135188A0/xx unknown
- 1998-09-24 HU HU0003931A patent/HUP0003931A2/hu unknown
- 1998-09-24 JP JP2000512547A patent/JP2002500162A/ja not_active Withdrawn
- 1998-09-24 WO PCT/US1998/019987 patent/WO1999015178A1/fr not_active Ceased
- 1998-09-24 TR TR2000/00786T patent/TR200000786T2/xx unknown
2000
- 2000-03-23 NO NO20001515A patent/NO20001515L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
AU9578798A (en)	1999-04-12
TR200000786T2 (tr)	2000-08-21
CA2304000A1 (fr)	1999-04-01
IL135188A0 (en)	2001-05-20
NO20001515D0 (no)	2000-03-23
EP1023073A1 (fr)	2000-08-02
HUP0003931A2 (hu)	2001-10-28
BR9813214A (pt)	2000-08-29
PL339414A1 (en)	2000-12-18
CN1271284A (zh)	2000-10-25
KR20010024249A (ko)	2001-03-26
WO1999015178A1 (fr)	1999-04-01
NO20001515L (no)	2000-03-23

Legal Events

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2006-01-10

A300

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Effective date: 20060110

Publication	Publication Date	Title
JP4491072B2 (ja)	2010-06-30	ビトロネクチンレセプター拮抗物質
JP2002500162A (ja)	2002-01-08	ビトロネクチン受容体アンタゴニスト
JP2002528380A (ja)	2002-09-03	ビトロネクチン受容体アンタゴニスト
JP2001508067A (ja)	2001-06-19	ビトロネクチン受容体アンタゴニスト
JP2001517658A (ja)	2001-10-09	ビトロネクチン受容体アンタゴニスト
US6495560B1 (en)	2002-12-17	Vitronectin receptor antagonist
US20020019387A1 (en)	2002-02-14	Vitronectin receptor antagonist
JP2002522360A (ja)	2002-07-23	ビトロネクチン受容体アンタゴニスト
US20010014737A1 (en)	2001-08-16	Vitronectin receptor antagonist
US6576643B2 (en)	2003-06-10	Vitronectin receptor antagonists
CZ20001061A3 (cs)	2000-12-13	Antagonista receptoru pro vitronektin
MXPA00002895A (en)	2001-12-04	Vitronectin receptor antagonist
CZ2000979A3 (cs)	2000-11-15	Antagonista vitronektinového receptoru
MXPA00002896A (en)	2001-12-04	Vitronectin receptor antagonist
CZ20001060A3 (cs)	2000-11-15	Antagonista receptoru vitronektinu