CA2304961A1 - Procedes et compositions utilises pour lier des cellules souches hematopoietiques - Google Patents
Procedes et compositions utilises pour lier des cellules souches hematopoietiques Download PDFInfo
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- CA2304961A1 CA2304961A1 CA002304961A CA2304961A CA2304961A1 CA 2304961 A1 CA2304961 A1 CA 2304961A1 CA 002304961 A CA002304961 A CA 002304961A CA 2304961 A CA2304961 A CA 2304961A CA 2304961 A1 CA2304961 A1 CA 2304961A1
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- stem cells
- lectin
- cells
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- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- 229910052722 tritium Inorganic materials 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 230000035899 viability Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Abstract
L'invention concerne des procédés et des compositions utilisés pour lier des cellules souches hématopoïétiques. Les procédés de l'invention consistent généralement à utiliser un partenaire de liaison qui forme un complexe avec une structure à base de lactosamine syalylée présente sur la surface des cellules souches. La formation desdits complexes facilite, par exemple, l'immobilisation, la purification, l'identification et le ciblage de cellules souches hématopoïétiques. Lesdites compositions de l'invention comprennent généralement un partenaire de liaison qui peut être libre, fixé à un matériau de support ou lié à un agent marqueur ou thérapeutique.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5997297P | 1997-09-25 | 1997-09-25 | |
| US60/059,972 | 1997-09-25 | ||
| PCT/US1998/020063 WO1999015628A1 (fr) | 1997-09-25 | 1998-09-24 | Procedes et compositions utilises pour lier des cellules souches hematopoietiques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2304961A1 true CA2304961A1 (fr) | 1999-04-01 |
Family
ID=22026508
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002304961A Abandoned CA2304961A1 (fr) | 1997-09-25 | 1998-09-24 | Procedes et compositions utilises pour lier des cellules souches hematopoietiques |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1017790A1 (fr) |
| JP (1) | JP2001517427A (fr) |
| CN (1) | CN1280611A (fr) |
| AU (1) | AU9508998A (fr) |
| CA (1) | CA2304961A1 (fr) |
| WO (1) | WO1999015628A1 (fr) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1167518B1 (fr) * | 1999-03-30 | 2005-10-26 | Netech Inc. | Procede de separation selective de cellules sanguines au moyen de lectine |
| WO2001072392A2 (fr) * | 2000-03-14 | 2001-10-04 | Exiqon A/S | Procede de separation et d'isolation de sous-populations de cellules dans des echantillons biologiques |
| US6992178B2 (en) * | 2000-11-15 | 2006-01-31 | Two Cells Co., Ltd. | Agent imparting resistance to external stimuli |
| CA2519975C (fr) * | 2003-04-08 | 2013-07-02 | Yeda Research And Development Co. Ltd | Cellules souches presentant une sensibilite accrue a un agent chimio-attractif, methodes de production et d'utilisation associees |
| US8691774B2 (en) | 2005-07-11 | 2014-04-08 | Glykos Finland Oy | Carbohydrate profile compositions from human cells and methods for analysis and modification thereof |
| WO2007054622A1 (fr) * | 2005-11-08 | 2007-05-18 | Suomen Punainen Risti, Veripalvelu | Nouvelles compositions a profils glucidiques tirees de cellules humaines et procedes d'analyse et de modification correspondants |
| AU2007264846A1 (en) * | 2006-06-29 | 2008-01-03 | Glykos Finland Oy | Novel cellular glycan compositions |
| KR20080037883A (ko) * | 2006-10-27 | 2008-05-02 | 세원셀론텍(주) | 메디컬 키트 및 이의 사용방법 |
| CA2676323A1 (fr) * | 2007-01-18 | 2008-07-24 | Suomen Punainen Risti, Veripalvelu | Nouveaux procedes et reactifs pour la production de cellules |
| WO2008087258A1 (fr) * | 2007-01-18 | 2008-07-24 | Suomen Punainen Risti, Veripalvelu | Nouveaux glucides issus de cellules humaines et méthodes d'analyse et de modification |
| WO2012168295A1 (fr) * | 2011-06-06 | 2012-12-13 | ReGenesys BVBA | Multiplication de cellules souches dans des bioréacteurs à fibres creuses |
| WO2013060282A1 (fr) * | 2011-10-28 | 2013-05-02 | Lu Leilei | Procédé et kit pour enrichir et purifier des cellules souches, et utilisations associées |
| WO2013060283A1 (fr) * | 2011-10-28 | 2013-05-02 | Li Fusheng | Procédé d'utilisation de lectines pour reconnaître et purifier des cellules souches, kits de réactifs et procédé d'application associé |
| CN104619388B (zh) * | 2012-05-31 | 2016-06-22 | 新加坡科技研究局 | 生物靶标与固相酰脲的选择性结合 |
| JP6057574B2 (ja) * | 2012-07-11 | 2017-01-11 | キヤノン株式会社 | 造血幹細胞識別用プローブ |
| CN108350077A (zh) * | 2015-11-03 | 2018-07-31 | 糖模拟物有限公司 | 产生单克隆抗体、造血干细胞的方法和组合物以及利用所述抗体和造血干细胞的方法 |
| CN113508141B (zh) * | 2019-02-01 | 2024-10-29 | 住友化学株式会社 | 抗体及其功能片段 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5227160A (en) * | 1988-07-15 | 1993-07-13 | The Biomembrane Institute | Monoclonal antibody nuh2 capable of inactivating motility of human sperm, antigen defined by said monoclonal antibody and methods of using said monoclonal antibody and antigen |
| IL106255A0 (en) * | 1993-04-23 | 1993-11-15 | Baxter Int | Method for isolating human blood cells |
-
1998
- 1998-09-24 CA CA002304961A patent/CA2304961A1/fr not_active Abandoned
- 1998-09-24 EP EP98948540A patent/EP1017790A1/fr not_active Withdrawn
- 1998-09-24 AU AU95089/98A patent/AU9508998A/en not_active Abandoned
- 1998-09-24 WO PCT/US1998/020063 patent/WO1999015628A1/fr not_active Ceased
- 1998-09-24 JP JP2000512922A patent/JP2001517427A/ja not_active Withdrawn
- 1998-09-24 CN CN98811483.6A patent/CN1280611A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP1017790A1 (fr) | 2000-07-12 |
| WO1999015628A1 (fr) | 1999-04-01 |
| JP2001517427A (ja) | 2001-10-09 |
| AU9508998A (en) | 1999-04-12 |
| CN1280611A (zh) | 2001-01-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |