CA2319468A1 - Sensitizing cells to compounds using lipid-mediated gene and compound delivery - Google Patents

Sensitizing cells to compounds using lipid-mediated gene and compound delivery Download PDF

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Publication number
CA2319468A1
CA2319468A1 CA002319468A CA2319468A CA2319468A1 CA 2319468 A1 CA2319468 A1 CA 2319468A1 CA 002319468 A CA002319468 A CA 002319468A CA 2319468 A CA2319468 A CA 2319468A CA 2319468 A1 CA2319468 A1 CA 2319468A1
Authority
CA
Canada
Prior art keywords
lipid
nucleic acid
compound
lipid formulation
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002319468A
Other languages
English (en)
French (fr)
Inventor
Ian Maclachlan
Roger W. Graham
Susan S. Buchkowsky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Inex Pharmaceuticals Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27535971&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2319468(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Publication of CA2319468A1 publication Critical patent/CA2319468A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/208—IL-12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45—Transferases (2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/51—Lyases (4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA002319468A 1998-02-03 1999-02-03 Sensitizing cells to compounds using lipid-mediated gene and compound delivery Abandoned CA2319468A1 (en)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US7359898P 1998-02-03 1998-02-03
US60/073,598 1998-02-03
US8691798P 1998-05-27 1998-05-27
US60/086,917 1998-05-27
US10142998P 1998-09-22 1998-09-22
US60/101,429 1998-09-22
US11238498P 1998-12-14 1998-12-14
US60/112,384 1998-12-14
US24310299A 1999-02-02 1999-02-02
US09/243,104 1999-02-02
PCT/CA1999/000089 WO1999039740A2 (en) 1998-02-03 1999-02-03 Sensitizing cells to compounds using lipid-mediated gene and compound delivery

Publications (1)

Publication Number Publication Date
CA2319468A1 true CA2319468A1 (en) 1999-08-12

Family

ID=27535971

Family Applications (2)

Application Number Title Priority Date Filing Date
CA002319468A Abandoned CA2319468A1 (en) 1998-02-03 1999-02-03 Sensitizing cells to compounds using lipid-mediated gene and compound delivery
CA2321837A Expired - Lifetime CA2321837C (en) 1998-02-03 1999-02-03 Systemic delivery of serum stable plasmid lipid particles for cancer therapy

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2321837A Expired - Lifetime CA2321837C (en) 1998-02-03 1999-02-03 Systemic delivery of serum stable plasmid lipid particles for cancer therapy

Country Status (7)

Country Link
EP (1) EP1053023B2 (de)
JP (1) JP2002502831A (de)
AT (1) ATE366121T1 (de)
AU (1) AU749881B2 (de)
CA (2) CA2319468A1 (de)
DE (1) DE69936444T3 (de)
WO (2) WO1999039741A2 (de)

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Also Published As

Publication number Publication date
WO1999039740A2 (en) 1999-08-12
CA2321837C (en) 2011-08-16
JP2002502831A (ja) 2002-01-29
CA2321837A1 (en) 1999-08-12
WO1999039740A8 (en) 1999-09-23
WO1999039740A3 (en) 1999-10-28
DE69936444D1 (de) 2007-08-16
EP1053023B1 (de) 2007-07-04
AU749881B2 (en) 2002-07-04
WO1999039741A2 (en) 1999-08-12
DE69936444T2 (de) 2008-03-20
ATE366121T1 (de) 2007-07-15
AU2405799A (en) 1999-08-23
WO1999039741A3 (en) 1999-09-30
EP1053023B2 (de) 2011-03-30
DE69936444T3 (de) 2012-05-10
WO1999039740A9 (en) 1999-11-25
EP1053023A2 (de) 2000-11-22

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued