CA2373643A1 - Agents anti-tumorales contenant des composes de boroproline - Google Patents
Agents anti-tumorales contenant des composes de boroproline Download PDFInfo
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- CA2373643A1 CA2373643A1 CA002373643A CA2373643A CA2373643A1 CA 2373643 A1 CA2373643 A1 CA 2373643A1 CA 002373643 A CA002373643 A CA 002373643A CA 2373643 A CA2373643 A CA 2373643A CA 2373643 A1 CA2373643 A1 CA 2373643A1
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- agent
- cancer
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- carcinoma
- tumor
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
L'invention concerne une méthode de traitement de patients sujets à une prolifération cellulaire anormale. Cette méthode consiste à administrer aux patients nécessitant un tel traitement, une quantité efficace d'un agent de formule (I), pour inhiber la prolifération cellulaire telle celle liée à une croissance tumorale ou à une métastase. Ladite invention a également trait à une méthode d'inhibition d'une angiogenèse dans une masse cellulaire proliférant anormalement, en administrant un agent de formule (I). Les composés préférés sont des dérivés de boroproline.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13586199P | 1999-05-25 | 1999-05-25 | |
| US60/135,861 | 1999-05-25 | ||
| PCT/US2000/014505 WO2000071135A1 (fr) | 1999-05-25 | 2000-05-25 | Agents anti-tumorales contenant des composes de boroproline |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2373643A1 true CA2373643A1 (fr) | 2000-11-30 |
Family
ID=22470056
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002373643A Abandoned CA2373643A1 (fr) | 1999-05-25 | 2000-05-25 | Agents anti-tumorales contenant des composes de boroproline |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1187619A1 (fr) |
| JP (1) | JP2003500360A (fr) |
| AU (1) | AU781897B2 (fr) |
| CA (1) | CA2373643A1 (fr) |
| HK (1) | HK1046846A1 (fr) |
| WO (1) | WO2000071135A1 (fr) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2304206A1 (fr) | 1997-09-29 | 1999-04-08 | Point Therapeutics, Inc. | Stimulation de cellules hematopoietiques in vitro |
| GB9803448D0 (en) | 1998-02-18 | 1998-04-15 | Pharma Mar Sa | Pharmaceutical formulation |
| US6890904B1 (en) | 1999-05-25 | 2005-05-10 | Point Therapeutics, Inc. | Anti-tumor agents |
| UA76718C2 (uk) | 2000-06-30 | 2006-09-15 | Фарма Мар, С.А. | Протипухлинні похідні аплідину |
| HK1054191A1 (zh) | 2000-10-12 | 2003-11-21 | Pharma Mar, S.A. | 施用aplidine時同時使用myoprotector的癌症治療 |
| WO2003037373A1 (fr) * | 2001-10-31 | 2003-05-08 | Medical Research Council | Utiilisation d'un antagoniste du recepteur ep2 ou ep4 et/ou d'un inhibiteur de la cox-1 pour traiter un cancer cervical |
| EP2316470A3 (fr) * | 2001-11-26 | 2011-08-24 | Trustees Of Tufts College | Inhibiteurs peptidomimétiques d'enzymes de clivage post-proline |
| JP2003267966A (ja) * | 2002-03-13 | 2003-09-25 | Pola Chem Ind Inc | フラバン誘導体、皮膚線維芽細胞増殖抑制剤および皮膚外用剤 |
| AU2003248921A1 (en) * | 2002-07-09 | 2004-01-23 | Point Therapeutics, Inc. | Boroproline compound combination therapy |
| ATE406171T1 (de) | 2003-03-12 | 2008-09-15 | Dana Farber Cancer Inst Inc | Aplidine zur behandlung von multiplem myelom |
| JP2006523212A (ja) * | 2003-03-13 | 2006-10-12 | スリーエム イノベイティブ プロパティズ カンパニー | 皮膚病変の診断方法 |
| DOP2006000008A (es) | 2005-01-10 | 2006-08-31 | Arena Pharm Inc | Terapia combinada para el tratamiento de la diabetes y afecciones relacionadas y para el tratamiento de afecciones que mejoran mediante un incremento de la concentración sanguínea de glp-1 |
| PE20071221A1 (es) | 2006-04-11 | 2007-12-14 | Arena Pharm Inc | Agonistas del receptor gpr119 en metodos para aumentar la masa osea y para tratar la osteoporosis y otras afecciones caracterizadas por masa osea baja, y la terapia combinada relacionada a estos agonistas |
| EP2146210A1 (fr) | 2008-04-07 | 2010-01-20 | Arena Pharmaceuticals, Inc. | Procédés d'utilisation du récepteur couplé aux protéines A G pour identifier les secrétagogues de peptide YY (PYY) et composés utiles dans le traitement d'états modulés par PYY |
| US8835506B2 (en) | 2008-06-05 | 2014-09-16 | Stc.Unm | Methods and related compositions for the treatment of cancer |
| AR077642A1 (es) | 2009-07-09 | 2011-09-14 | Arena Pharm Inc | Moduladores del metabolismo y el tratamiento de trastornos relacionados con el mismo |
| MX2012011631A (es) | 2010-04-06 | 2013-01-18 | Arena Pharm Inc | Moduladores del receptor gpr119 y el tratamiento de trastornos relacionados con el mismo. |
| MX2013003184A (es) | 2010-09-22 | 2013-06-07 | Arena Pharm Inc | Moduladores del receptor gpr119 y el tratamiento de transtornos relacionados con el mismo. |
| WO2012135570A1 (fr) | 2011-04-01 | 2012-10-04 | Arena Pharmaceuticals, Inc. | Modulateurs du récepteur gpr119 et traitement de troubles qui lui sont associés |
| WO2012145361A1 (fr) | 2011-04-19 | 2012-10-26 | Arena Pharmaceuticals, Inc. | Modulateurs du récepteur gpr119 et traitement de troubles liés à celui-ci |
| US20140038889A1 (en) | 2011-04-22 | 2014-02-06 | Arena Pharmaceuticals, Inc. | Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto |
| US20140051714A1 (en) | 2011-04-22 | 2014-02-20 | Arena Pharmaceuticals, Inc. | Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto |
| WO2012170702A1 (fr) | 2011-06-08 | 2012-12-13 | Arena Pharmaceuticals, Inc. | Modulateurs du récepteur gpr119 et traitement de troubles associés à celui-ci |
| WO2013055910A1 (fr) | 2011-10-12 | 2013-04-18 | Arena Pharmaceuticals, Inc. | Modulateurs du récepteur gpr119 et traitement de troubles associés |
| US9284337B2 (en) | 2011-11-22 | 2016-03-15 | Trustees Of Tufts College | Small molecule enhancer for dendritic cell cancer vaccines |
| WO2014074668A1 (fr) | 2012-11-08 | 2014-05-15 | Arena Pharmaceuticals, Inc. | Modulateurs de gpr119 et traitement de troubles associés à ceux-ci |
| HK1249847A1 (zh) | 2015-03-09 | 2018-11-16 | Intekrin Therapeutics, Inc. | 用於治疗非酒精性脂肪肝疾病和/或脂肪营养不良的方法 |
| CN110035766B9 (zh) * | 2016-09-21 | 2023-12-15 | 新加坡科技研究局 | 用于抑制皮肤炎症和确定癌症易感性的方法和组合物 |
| KR20200036808A (ko) | 2017-04-03 | 2020-04-07 | 코히러스 바이오사이언시스, 인크. | 진행성 핵상 마비 치료를 위한 PPARγ 작용제 |
| WO2020123477A1 (fr) * | 2018-12-10 | 2020-06-18 | Bioxcel Therapeutics, Inc. | Traitements combinés pour traiter des maladies à l'aide d'un agent modifiant l'immunité innée et d'un agoniste de l'ox40 |
| CN115779148B (zh) * | 2021-09-09 | 2024-02-23 | 中国科学院福建物质结构研究所 | 一种牙种植体表面涂层及其制备方法和应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02268118A (ja) * | 1989-04-07 | 1990-11-01 | Mitsubishi Gas Chem Co Inc | 免疫賦活剤 |
| US5328936A (en) * | 1993-02-01 | 1994-07-12 | Rohm And Haas Company | Polymerization process for making porous polymeric particles |
| IL111785A0 (en) * | 1993-12-03 | 1995-01-24 | Ferring Bv | Dp-iv inhibitors and pharmaceutical compositions containing them |
| US5767242A (en) * | 1994-04-20 | 1998-06-16 | Boehringer Ingelheim Int'l Gmbh | Isolated dimeric fibroblast activation protein alpha, and uses thereof |
| US5952301A (en) * | 1996-12-10 | 1999-09-14 | 1149336 Ontario Inc. | Compositions and methods for enhancing intestinal function |
| US6100234A (en) * | 1997-05-07 | 2000-08-08 | Tufts University | Treatment of HIV |
| WO1999062914A1 (fr) * | 1998-06-05 | 1999-12-09 | Point Therapeutics, Inc. | Composes cycliques de boroproline |
| CA2339537A1 (fr) * | 1998-08-21 | 2000-03-02 | Barbara Wallner | Regulation de l'activite de substrat |
-
2000
- 2000-05-25 CA CA002373643A patent/CA2373643A1/fr not_active Abandoned
- 2000-05-25 HK HK02106843.4A patent/HK1046846A1/zh unknown
- 2000-05-25 JP JP2000619438A patent/JP2003500360A/ja active Pending
- 2000-05-25 EP EP00937801A patent/EP1187619A1/fr not_active Withdrawn
- 2000-05-25 AU AU52927/00A patent/AU781897B2/en not_active Ceased
- 2000-05-25 WO PCT/US2000/014505 patent/WO2000071135A1/fr not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP1187619A1 (fr) | 2002-03-20 |
| AU781897B2 (en) | 2005-06-23 |
| AU5292700A (en) | 2000-12-12 |
| HK1046846A1 (zh) | 2003-01-30 |
| WO2000071135A1 (fr) | 2000-11-30 |
| JP2003500360A (ja) | 2003-01-07 |
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| FZDE | Dead |