CA2373643A1 - Agents anti-tumorales contenant des composes de boroproline - Google Patents
Agents anti-tumorales contenant des composes de boroproline Download PDFInfo
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- CA2373643A1 CA2373643A1 CA002373643A CA2373643A CA2373643A1 CA 2373643 A1 CA2373643 A1 CA 2373643A1 CA 002373643 A CA002373643 A CA 002373643A CA 2373643 A CA2373643 A CA 2373643A CA 2373643 A1 CA2373643 A1 CA 2373643A1
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- agent
- cancer
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- carcinoma
- tumor
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Classifications
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
L'invention concerne une méthode de traitement de patients sujets à une prolifération cellulaire anormale. Cette méthode consiste à administrer aux patients nécessitant un tel traitement, une quantité efficace d'un agent de formule (I), pour inhiber la prolifération cellulaire telle celle liée à une croissance tumorale ou à une métastase. Ladite invention a également trait à une méthode d'inhibition d'une angiogenèse dans une masse cellulaire proliférant anormalement, en administrant un agent de formule (I). Les composés préférés sont des dérivés de boroproline.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13586199P | 1999-05-25 | 1999-05-25 | |
| US60/135,861 | 1999-05-25 | ||
| PCT/US2000/014505 WO2000071135A1 (fr) | 1999-05-25 | 2000-05-25 | Agents anti-tumorales contenant des composes de boroproline |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2373643A1 true CA2373643A1 (fr) | 2000-11-30 |
Family
ID=22470056
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002373643A Abandoned CA2373643A1 (fr) | 1999-05-25 | 2000-05-25 | Agents anti-tumorales contenant des composes de boroproline |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1187619A1 (fr) |
| JP (1) | JP2003500360A (fr) |
| AU (1) | AU781897B2 (fr) |
| CA (1) | CA2373643A1 (fr) |
| HK (1) | HK1046846A1 (fr) |
| WO (1) | WO2000071135A1 (fr) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2304206A1 (fr) | 1997-09-29 | 1999-04-08 | Point Therapeutics, Inc. | Stimulation de cellules hematopoietiques in vitro |
| GB9803448D0 (en) | 1998-02-18 | 1998-04-15 | Pharma Mar Sa | Pharmaceutical formulation |
| US6890904B1 (en) | 1999-05-25 | 2005-05-10 | Point Therapeutics, Inc. | Anti-tumor agents |
| UA76718C2 (uk) | 2000-06-30 | 2006-09-15 | Фарма Мар, С.А. | Протипухлинні похідні аплідину |
| CZ2003993A3 (cs) | 2000-10-12 | 2004-02-18 | Pharma Mar, S. A. | Léčivo pro léčení rakoviny podáváním aplidinu nebo analogu aplidinu a protektoru kosterního svalstva |
| WO2003037373A1 (fr) * | 2001-10-31 | 2003-05-08 | Medical Research Council | Utiilisation d'un antagoniste du recepteur ep2 ou ep4 et/ou d'un inhibiteur de la cox-1 pour traiter un cancer cervical |
| EP1469873A4 (fr) | 2001-11-26 | 2007-10-03 | Tufts College | Inhibiteurs peptidomimetiques d'enzymes de clivage post-proline |
| JP2003267966A (ja) * | 2002-03-13 | 2003-09-25 | Pola Chem Ind Inc | フラバン誘導体、皮膚線維芽細胞増殖抑制剤および皮膚外用剤 |
| US20050084490A1 (en) * | 2002-07-09 | 2005-04-21 | Point Therapeutics, Inc. | Boroproline compound combination therapy |
| ATE406171T1 (de) | 2003-03-12 | 2008-09-15 | Dana Farber Cancer Inst Inc | Aplidine zur behandlung von multiplem myelom |
| CA2518082C (fr) * | 2003-03-13 | 2013-02-12 | 3M Innovative Properties Company | Methodes de diagnostic de lesions de la peau |
| DOP2006000008A (es) | 2005-01-10 | 2006-08-31 | Arena Pharm Inc | Terapia combinada para el tratamiento de la diabetes y afecciones relacionadas y para el tratamiento de afecciones que mejoran mediante un incremento de la concentración sanguínea de glp-1 |
| PE20071221A1 (es) | 2006-04-11 | 2007-12-14 | Arena Pharm Inc | Agonistas del receptor gpr119 en metodos para aumentar la masa osea y para tratar la osteoporosis y otras afecciones caracterizadas por masa osea baja, y la terapia combinada relacionada a estos agonistas |
| EP2108960A1 (fr) | 2008-04-07 | 2009-10-14 | Arena Pharmaceuticals, Inc. | Procédés d'utilisation d'un récepteur couplé à protéine G pour identifier les secrétagogues de peptide YY (PYY) et composés utiles dans le traitement des conditions modulées de secrétagogues BY (PYY) et composés utiles dans le traitement des conditions par PYY |
| US8835506B2 (en) | 2008-06-05 | 2014-09-16 | Stc.Unm | Methods and related compositions for the treatment of cancer |
| AR077642A1 (es) | 2009-07-09 | 2011-09-14 | Arena Pharm Inc | Moduladores del metabolismo y el tratamiento de trastornos relacionados con el mismo |
| AU2011237775A1 (en) | 2010-04-06 | 2012-11-22 | Arena Pharmaceuticals, Inc. | Modulators of the GPR119 receptor and the treatment of disorders related thereto |
| PH12013500547A1 (en) | 2010-09-22 | 2013-06-10 | Arena Pharm Inc | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
| US20140018371A1 (en) | 2011-04-01 | 2014-01-16 | Arena Pharmaceuticals, Inc. | Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto |
| US20140066369A1 (en) | 2011-04-19 | 2014-03-06 | Arena Pharmaceuticals, Inc. | Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto |
| WO2012145604A1 (fr) | 2011-04-22 | 2012-10-26 | Arena Pharmaceuticals, Inc. | Modulateurs du récepteur gpr119 et traitement de troubles liés à celui-ci |
| US20140038889A1 (en) | 2011-04-22 | 2014-02-06 | Arena Pharmaceuticals, Inc. | Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto |
| WO2012170702A1 (fr) | 2011-06-08 | 2012-12-13 | Arena Pharmaceuticals, Inc. | Modulateurs du récepteur gpr119 et traitement de troubles associés à celui-ci |
| WO2013055910A1 (fr) | 2011-10-12 | 2013-04-18 | Arena Pharmaceuticals, Inc. | Modulateurs du récepteur gpr119 et traitement de troubles associés |
| CN104039952A (zh) * | 2011-11-22 | 2014-09-10 | 塔夫茨大学信托人 | 用于树突状细胞癌症疫苗的小分子增强剂 |
| WO2014074668A1 (fr) | 2012-11-08 | 2014-05-15 | Arena Pharmaceuticals, Inc. | Modulateurs de gpr119 et traitement de troubles associés à ceux-ci |
| EA201791982A1 (ru) | 2015-03-09 | 2020-02-17 | Интекрин Терапьютикс, Инк. | Способы лечения неалкогольной жировой болезни печени и/или липодистрофии |
| WO2018056907A1 (fr) * | 2016-09-21 | 2018-03-29 | Agency For Science, Technology And Research | Procédés et compositions pour inhiber l'inflammation de la peau et de déterminer la susceptibilité au cancer |
| AU2018249822A1 (en) | 2017-04-03 | 2019-10-31 | Coherus Biosciences Inc. | PPArgamma agonist for treatment of progressive supranuclear palsy |
| WO2020123477A1 (fr) * | 2018-12-10 | 2020-06-18 | Bioxcel Therapeutics, Inc. | Traitements combinés pour traiter des maladies à l'aide d'un agent modifiant l'immunité innée et d'un agoniste de l'ox40 |
| CN115779148B (zh) * | 2021-09-09 | 2024-02-23 | 中国科学院福建物质结构研究所 | 一种牙种植体表面涂层及其制备方法和应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02268118A (ja) * | 1989-04-07 | 1990-11-01 | Mitsubishi Gas Chem Co Inc | 免疫賦活剤 |
| US5328936A (en) * | 1993-02-01 | 1994-07-12 | Rohm And Haas Company | Polymerization process for making porous polymeric particles |
| IL111785A0 (en) * | 1993-12-03 | 1995-01-24 | Ferring Bv | Dp-iv inhibitors and pharmaceutical compositions containing them |
| US5767242A (en) * | 1994-04-20 | 1998-06-16 | Boehringer Ingelheim Int'l Gmbh | Isolated dimeric fibroblast activation protein alpha, and uses thereof |
| US5952301A (en) * | 1996-12-10 | 1999-09-14 | 1149336 Ontario Inc. | Compositions and methods for enhancing intestinal function |
| US6100234A (en) * | 1997-05-07 | 2000-08-08 | Tufts University | Treatment of HIV |
| AU765370B2 (en) * | 1998-06-05 | 2003-09-18 | Point Therapeutics, Inc. | Cyclic boroproline compounds |
| EP1104293A1 (fr) * | 1998-08-21 | 2001-06-06 | Point Therapeutics, Inc. | Regulation de l'activite de substrat |
-
2000
- 2000-05-25 EP EP00937801A patent/EP1187619A1/fr not_active Withdrawn
- 2000-05-25 AU AU52927/00A patent/AU781897B2/en not_active Ceased
- 2000-05-25 CA CA002373643A patent/CA2373643A1/fr not_active Abandoned
- 2000-05-25 WO PCT/US2000/014505 patent/WO2000071135A1/fr not_active Ceased
- 2000-05-25 JP JP2000619438A patent/JP2003500360A/ja active Pending
- 2000-05-25 HK HK02106843.4A patent/HK1046846A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000071135A1 (fr) | 2000-11-30 |
| AU5292700A (en) | 2000-12-12 |
| JP2003500360A (ja) | 2003-01-07 |
| HK1046846A1 (zh) | 2003-01-30 |
| EP1187619A1 (fr) | 2002-03-20 |
| AU781897B2 (en) | 2005-06-23 |
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