CA2417258A1 - Systeme d'aromatisation pour compositions pharmaceutiques et procedes de fabrication de telles compositions - Google Patents
Systeme d'aromatisation pour compositions pharmaceutiques et procedes de fabrication de telles compositions Download PDFInfo
- Publication number
- CA2417258A1 CA2417258A1 CA002417258A CA2417258A CA2417258A1 CA 2417258 A1 CA2417258 A1 CA 2417258A1 CA 002417258 A CA002417258 A CA 002417258A CA 2417258 A CA2417258 A CA 2417258A CA 2417258 A1 CA2417258 A1 CA 2417258A1
- Authority
- CA
- Canada
- Prior art keywords
- flavored
- weight
- pharmaceutical composition
- mixtures
- ingredient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract description 164
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- 239000013543 active substance Substances 0.000 claims abstract description 81
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- NCDNCNXCDXHOMX-XGKFQTDJSA-N ritonavir Chemical compound N([C@@H](C(C)C)C(=O)N[C@H](C[C@H](O)[C@H](CC=1C=CC=CC=1)NC(=O)OCC=1SC=NC=1)CC=1C=CC=CC=1)C(=O)N(C)CC1=CSC(C(C)C)=N1 NCDNCNXCDXHOMX-XGKFQTDJSA-N 0.000 claims abstract description 63
- KJHKTHWMRKYKJE-SUGCFTRWSA-N Kaletra Chemical compound N1([C@@H](C(C)C)C(=O)N[C@H](C[C@H](O)[C@H](CC=2C=CC=CC=2)NC(=O)COC=2C(=CC=CC=2C)C)CC=2C=CC=CC=2)CCCNC1=O KJHKTHWMRKYKJE-SUGCFTRWSA-N 0.000 claims abstract description 58
- NCDNCNXCDXHOMX-UHFFFAOYSA-N Ritonavir Natural products C=1C=CC=CC=1CC(NC(=O)OCC=1SC=NC=1)C(O)CC(CC=1C=CC=CC=1)NC(=O)C(C(C)C)NC(=O)N(C)CC1=CSC(C(C)C)=N1 NCDNCNXCDXHOMX-UHFFFAOYSA-N 0.000 claims abstract description 56
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Fats And Perfumes (AREA)
Abstract
L'invention concerne un système d'aromatisation pour une composition pharmaceutique liquides, ainsi que des compositions pharmaceutiques contenant de tels systèmes d'aromatisation. Les systèmes d'aromatisation de cette invention comprennent au moins un édulcorant, au moins deux ingrédients aromatisés, et au moins un modificateur d'arôme choisi dans le groupe comprenant acide citrique, citrate de sodium, chlorure de sodium et des mélanges de ceux-ci. Au moins deux des ingrédients aromatisés sont choisis dans le groupe comprenant un ingrédient aromatisé à la vanille, un ingrédient aromatisé à la menthe poivrée, un ingrédient aromatisé au menthol, un ingrédient aromatisé à la barbe à papa, et des mélanges de ceux-ci. Le ou les édulcorants comprennent de la glycérine, du glycyrrhizinate monoammonique, du sodium de saccharine, de l'acésulfame-potassium, du sirop de glucose à haute teneur en fructose, et/ou des mélanges de ceux-ci. Les compositions pharmaceutiques de cette invention comprennent un système d'aromatisation de l'invention, un système de solvant, et au moins un agent actif du point de vue pharmaceutique, tel que du lopinavir ou des dérivés de celui-ci, du ritonavir ou des dérivés de celui-ci, ou des mélanges de ceux-ci. L'invention concerne également des procédés de fabrication de telles compositions pharmaceutiques liquides.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65519200A | 2000-09-05 | 2000-09-05 | |
| US09/655,192 | 2000-09-05 | ||
| PCT/US2001/027415 WO2002020057A2 (fr) | 2000-09-05 | 2001-09-04 | Systeme d'aromatisation pour compositions pharmaceutiques et procedes de fabrication de telles compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2417258A1 true CA2417258A1 (fr) | 2002-03-14 |
Family
ID=24627898
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002417258A Abandoned CA2417258A1 (fr) | 2000-09-05 | 2001-09-04 | Systeme d'aromatisation pour compositions pharmaceutiques et procedes de fabrication de telles compositions |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1315487A2 (fr) |
| JP (1) | JP2004522698A (fr) |
| AR (1) | AR030715A1 (fr) |
| AU (1) | AU2001288695A1 (fr) |
| BR (1) | BR0108433A (fr) |
| CA (1) | CA2417258A1 (fr) |
| MX (1) | MXPA03001952A (fr) |
| PE (1) | PE20020373A1 (fr) |
| UY (1) | UY26925A1 (fr) |
| WO (1) | WO2002020057A2 (fr) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7364752B1 (en) | 1999-11-12 | 2008-04-29 | Abbott Laboratories | Solid dispersion pharamaceutical formulations |
| EP1175205B1 (fr) | 1999-11-12 | 2006-06-14 | Abbott Laboratories | Dispersion solide comrpenant ritonavir, fenofibrate ou griseofulvin |
| RU2005119299A (ru) * | 2002-11-22 | 2005-11-20 | Фирмениш Са (Ch) | Составы для ухода за полостью рта, маскирующие соленый вкус солей |
| US8025899B2 (en) | 2003-08-28 | 2011-09-27 | Abbott Laboratories | Solid pharmaceutical dosage form |
| GB2423711B (en) * | 2005-10-24 | 2007-02-14 | Fortune Apex Dev Ltd | Method for preparing a pharmaceutical composition with enhanced mucoadhesion |
| TW201340998A (zh) * | 2012-02-29 | 2013-10-16 | Takeda Pharmaceutical | 經口劑 |
| US8771651B2 (en) * | 2012-09-10 | 2014-07-08 | Johnson & Johnson Consumer Companies, Inc. | Mouth rinses and tooth sensitivity treatment compositions |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL111991A (en) * | 1994-01-28 | 2000-07-26 | Abbott Lab | Liquid pharmaceutical composition of HIV protease inhibitors in organic solvent |
| AU3146997A (en) * | 1996-06-03 | 1998-01-05 | Merck & Co., Inc. | Pediatric formulation for hiv protease inhibitors |
-
2001
- 2001-09-04 MX MXPA03001952A patent/MXPA03001952A/es unknown
- 2001-09-04 AU AU2001288695A patent/AU2001288695A1/en not_active Abandoned
- 2001-09-04 AR ARP010104207A patent/AR030715A1/es unknown
- 2001-09-04 JP JP2002524540A patent/JP2004522698A/ja not_active Withdrawn
- 2001-09-04 UY UY26925A patent/UY26925A1/es not_active Application Discontinuation
- 2001-09-04 WO PCT/US2001/027415 patent/WO2002020057A2/fr not_active Ceased
- 2001-09-04 EP EP01968449A patent/EP1315487A2/fr not_active Withdrawn
- 2001-09-04 CA CA002417258A patent/CA2417258A1/fr not_active Abandoned
- 2001-09-04 PE PE2001000889A patent/PE20020373A1/es not_active Application Discontinuation
- 2001-09-04 BR BRPI0108433-0A patent/BR0108433A/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA03001952A (es) | 2003-09-10 |
| EP1315487A2 (fr) | 2003-06-04 |
| JP2004522698A (ja) | 2004-07-29 |
| UY26925A1 (es) | 2002-04-26 |
| AR030715A1 (es) | 2003-09-03 |
| AU2001288695A1 (en) | 2002-03-22 |
| PE20020373A1 (es) | 2002-05-13 |
| WO2002020057A2 (fr) | 2002-03-14 |
| WO2002020057A3 (fr) | 2002-05-10 |
| BR0108433A (pt) | 2006-06-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |