CA2445013A1 - Polypeptides of an hdm2 protein-specific murine alpha/beta t-cell receptor, nucleic acids encoding these and their use - Google Patents
Polypeptides of an hdm2 protein-specific murine alpha/beta t-cell receptor, nucleic acids encoding these and their use Download PDFInfo
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- CA2445013A1 CA2445013A1 CA002445013A CA2445013A CA2445013A1 CA 2445013 A1 CA2445013 A1 CA 2445013A1 CA 002445013 A CA002445013 A CA 002445013A CA 2445013 A CA2445013 A CA 2445013A CA 2445013 A1 CA2445013 A1 CA 2445013A1
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- 108010003137 tyrosyltyrosine Proteins 0.000 description 1
- 241001515965 unidentified phage Species 0.000 description 1
- HBOMLICNUCNMMY-XLPZGREQSA-N zidovudine Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](N=[N+]=[N-])C1 HBOMLICNUCNMMY-XLPZGREQSA-N 0.000 description 1
- CPYIZQLXMGRKSW-UHFFFAOYSA-N zinc;iron(3+);oxygen(2-) Chemical class [O-2].[O-2].[O-2].[O-2].[Fe+3].[Fe+3].[Zn+2] CPYIZQLXMGRKSW-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10109854A DE10109854A1 (de) | 2001-03-01 | 2001-03-01 | Polypeptide eines hdm2-Protein spezifischen murinen alpha/beta T-Zell Rezeptors, diese kodierende Nukleinsäuren und deren Verwendung |
| DE10109854.5 | 2001-03-01 | ||
| PCT/EP2002/002187 WO2002070552A2 (de) | 2001-03-01 | 2002-02-28 | POLYPEPTIDE EINES HDM2-PROTEIN SPEZIFISCHEN MURINEN Α/β T-ZELL REZEPTORS, DIESE KODIERENDE NUKLEINSÜREN UND DEREN VERWENDUNG |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2445013A1 true CA2445013A1 (en) | 2002-09-12 |
Family
ID=7675927
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002445013A Abandoned CA2445013A1 (en) | 2001-03-01 | 2002-02-28 | Polypeptides of an hdm2 protein-specific murine alpha/beta t-cell receptor, nucleic acids encoding these and their use |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1363942A2 (de) |
| JP (1) | JP2004535778A (de) |
| CA (1) | CA2445013A1 (de) |
| DE (1) | DE10109854A1 (de) |
| WO (1) | WO2002070552A2 (de) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110070191A1 (en) * | 2008-03-19 | 2011-03-24 | Wong Hing C | T cell receptor fusions and conjugates and methods of use there of |
| US9062127B2 (en) | 2002-09-24 | 2015-06-23 | Johannes Gutenberg-Universitat Mainz | Method for rational mutagenesis of α/βT-cell receptors and correspondingly mutated MDM2-protein specific α/βT-cell receptors |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4832757B2 (ja) | 2002-09-11 | 2011-12-07 | エヌエックスピー ビー ヴィ | データ・キャリア整理分類方法 |
| DE10259713A1 (de) * | 2002-12-19 | 2004-07-08 | Johannes-Gutenberg-Universität Mainz | Verfahren zur Expressionsstabilisierung und Verbesserung der spezifischen Effektorfunktion von Einzelketten-Antigenerkennenden genetischen Konstrukten (scARC) und entsprechend mutierten MDM2-Protein spezifischen scT-Zell Rezeptoren |
| GB0427585D0 (en) * | 2004-12-16 | 2005-01-19 | Avidex Ltd | Assay |
| AU2011304728A1 (en) * | 2010-09-20 | 2013-03-14 | Biontech Ag | Antigen-specific T cell receptors and T cell epitopes |
| ES2861901T3 (es) | 2014-10-03 | 2021-10-06 | Univ Oxford Innovation Ltd | Análisis de monotipia de células T |
| CN107207371A (zh) * | 2014-10-20 | 2017-09-26 | 斯克利普斯研究院 | 用于选择结合配偶体的基于邻近度的方法 |
| AU2015338984A1 (en) * | 2014-10-31 | 2017-04-27 | The Trustees Of The University Of Pennsylvania | Methods and compositions for modified T cells |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU728794B2 (en) * | 1996-03-05 | 2001-01-18 | Scripps Research Institute, The | Recombinant constructs encoding T cell receptors specific for human HLA-restricted tumor antigens |
-
2001
- 2001-03-01 DE DE10109854A patent/DE10109854A1/de not_active Withdrawn
-
2002
- 2002-02-28 CA CA002445013A patent/CA2445013A1/en not_active Abandoned
- 2002-02-28 WO PCT/EP2002/002187 patent/WO2002070552A2/de not_active Ceased
- 2002-02-28 EP EP02722160A patent/EP1363942A2/de not_active Withdrawn
- 2002-02-28 JP JP2002569871A patent/JP2004535778A/ja active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9062127B2 (en) | 2002-09-24 | 2015-06-23 | Johannes Gutenberg-Universitat Mainz | Method for rational mutagenesis of α/βT-cell receptors and correspondingly mutated MDM2-protein specific α/βT-cell receptors |
| US20110070191A1 (en) * | 2008-03-19 | 2011-03-24 | Wong Hing C | T cell receptor fusions and conjugates and methods of use there of |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002070552A2 (de) | 2002-09-12 |
| DE10109854A1 (de) | 2002-09-12 |
| WO2002070552A3 (de) | 2002-12-12 |
| WO2002070552A8 (de) | 2002-10-10 |
| JP2004535778A (ja) | 2004-12-02 |
| EP1363942A2 (de) | 2003-11-26 |
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