CA2476481A1 - Amplification de la recombinase polymerase - Google Patents
Amplification de la recombinase polymerase Download PDFInfo
- Publication number
- CA2476481A1 CA2476481A1 CA002476481A CA2476481A CA2476481A1 CA 2476481 A1 CA2476481 A1 CA 2476481A1 CA 002476481 A CA002476481 A CA 002476481A CA 2476481 A CA2476481 A CA 2476481A CA 2476481 A1 CA2476481 A1 CA 2476481A1
- Authority
- CA
- Canada
- Prior art keywords
- primer
- strand
- rpa
- dna
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F16/00—Information retrieval; Database structures therefor; File system structures therefor
- G06F16/90—Details of database functions independent of the retrieved data types
- G06F16/95—Retrieval from the web
- G06F16/951—Indexing; Web crawling techniques
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F16/00—Information retrieval; Database structures therefor; File system structures therefor
- G06F16/90—Details of database functions independent of the retrieved data types
- G06F16/95—Retrieval from the web
- G06F16/957—Browsing optimisation, e.g. caching or content distillation
- G06F16/9574—Browsing optimisation, e.g. caching or content distillation of access to content, e.g. by caching
Landscapes
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Theoretical Computer Science (AREA)
- Databases & Information Systems (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Data Mining & Analysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Purification Treatments By Anaerobic Or Anaerobic And Aerobic Bacteria Or Animals (AREA)
- Polyesters Or Polycarbonates (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35856302P | 2002-02-21 | 2002-02-21 | |
| US60/358,563 | 2002-02-21 | ||
| PCT/US2003/005492 WO2003072805A2 (fr) | 2002-02-21 | 2003-02-21 | Amplification de la recombinase polymerase |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2476481A1 true CA2476481A1 (fr) | 2003-09-04 |
| CA2476481C CA2476481C (fr) | 2016-01-26 |
Family
ID=27765964
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2476481A Expired - Lifetime CA2476481C (fr) | 2002-02-21 | 2003-02-21 | Amplification de la recombinase polymerase |
Country Status (11)
| Country | Link |
|---|---|
| US (7) | US7270981B2 (fr) |
| EP (4) | EP2428588B1 (fr) |
| JP (4) | JP4340543B2 (fr) |
| AT (1) | ATE400663T1 (fr) |
| AU (1) | AU2003215391B2 (fr) |
| CA (1) | CA2476481C (fr) |
| DE (1) | DE60322044D1 (fr) |
| DK (1) | DK1499738T3 (fr) |
| ES (1) | ES2310237T3 (fr) |
| PT (1) | PT1499738E (fr) |
| WO (1) | WO2003072805A2 (fr) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7435561B2 (en) * | 2005-07-25 | 2008-10-14 | Asm Scientific, Inc. | Methods for multiplexing recombinase polymerase amplification |
| US7666598B2 (en) | 2002-02-21 | 2010-02-23 | Twistdx, Inc. | Recombinase polymerase amplification |
| US8030000B2 (en) | 2002-02-21 | 2011-10-04 | Alere San Diego, Inc. | Recombinase polymerase amplification |
| US8460875B2 (en) | 2002-02-21 | 2013-06-11 | Alere San Diego, Inc. | Recombinase polymerase amplification |
| US8637253B2 (en) | 2006-05-04 | 2014-01-28 | Alere San Diego, Inc. | Recombinase polymerase amplification |
| US8809021B2 (en) | 2011-04-07 | 2014-08-19 | Alere San Diego Inc. | Monitoring recombinase polymerase amplification mixtures |
| US9057097B2 (en) | 2009-06-05 | 2015-06-16 | Alere San Diego Inc. | Recombinase polymerase amplification reagents and kits |
| US9896719B2 (en) | 2009-05-20 | 2018-02-20 | Alere San Diego Inc. | DNA glycosylase/lyase and AP endonuclease substrates |
Families Citing this family (168)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6929915B2 (en) | 2001-04-20 | 2005-08-16 | The Penn State Research Foundation | Methods for nucleic acid manipulation |
| WO2005118853A2 (fr) * | 2004-06-01 | 2005-12-15 | Asm Scientific, Inc. | Amplification par recombinase polymerase |
| AU2003272438B2 (en) * | 2002-09-20 | 2009-04-02 | New England Biolabs, Inc. | Helicase dependent amplification of nucleic acids |
| WO2004092330A2 (fr) * | 2003-04-11 | 2004-10-28 | Applera Corporation | Methode permettant de generer de longues molecules d'acide nucleique d'une sequence definie |
| JP2005110621A (ja) * | 2003-10-10 | 2005-04-28 | Aisin Seiki Co Ltd | 核酸増幅方法及び核酸増幅用試薬キット |
| AU2011202896B2 (en) * | 2004-06-01 | 2012-12-06 | Abbott Diagnostics Scarborough, Inc. | Recombinase Polymerase Amplification |
| WO2005118608A2 (fr) | 2004-06-02 | 2005-12-15 | Asm Scientific, Inc. | Ribonucleotides modifies par 2'-nitrobenzyle |
| JP4534138B2 (ja) * | 2004-12-21 | 2010-09-01 | アイシン精機株式会社 | 核酸増幅反応における高度好熱菌由来タンパク質の活性化方法およびその利用 |
| US7579153B2 (en) * | 2005-01-25 | 2009-08-25 | Population Genetics Technologies, Ltd. | Isothermal DNA amplification |
| US7368265B2 (en) * | 2006-01-23 | 2008-05-06 | Compass Genetics, Llc | Selective genome amplification |
| AU2007338862B2 (en) | 2006-07-19 | 2014-02-06 | Bionano Genomics, Inc. | Nanonozzle device arrays: their preparation and use for macromolecular analysis |
| KR101522741B1 (ko) | 2007-03-28 | 2015-05-26 | 바이오나노 제노믹스, 인크. | 나노채널 어레이를 사용하는 거대분자 분석 방법 |
| US9689031B2 (en) | 2007-07-14 | 2017-06-27 | Ionian Technologies, Inc. | Nicking and extension amplification reaction for the exponential amplification of nucleic acids |
| US20090215050A1 (en) | 2008-02-22 | 2009-08-27 | Robert Delmar Jenison | Systems and methods for point-of-care amplification and detection of polynucleotides |
| US8628919B2 (en) | 2008-06-30 | 2014-01-14 | Bionano Genomics, Inc. | Methods and devices for single-molecule whole genome analysis |
| US8198028B2 (en) | 2008-07-02 | 2012-06-12 | Illumina Cambridge Limited | Using populations of beads for the fabrication of arrays on surfaces |
| WO2010059731A2 (fr) | 2008-11-18 | 2010-05-27 | Bionanomatrix, Inc. | Cartographie et séquences de polynucléotide |
| SG172965A1 (en) | 2009-01-13 | 2011-08-29 | Fluidigm Corp | Single-cell nucleic acid analysis |
| US8685648B2 (en) | 2009-02-03 | 2014-04-01 | Biohelix Corporation | Endonuclease-enhanced helicase-dependent amplification |
| US9309566B2 (en) | 2010-12-17 | 2016-04-12 | Life Technologies Corporation | Methods, compositions, systems, apparatuses and kits for nucleic acid amplification |
| US20120156728A1 (en) | 2010-12-17 | 2012-06-21 | Life Technologies Corporation | Clonal amplification of nucleic acid on solid surface with template walking |
| US9309557B2 (en) | 2010-12-17 | 2016-04-12 | Life Technologies Corporation | Nucleic acid amplification |
| US9334531B2 (en) | 2010-12-17 | 2016-05-10 | Life Technologies Corporation | Nucleic acid amplification |
| US20100299773A1 (en) * | 2009-05-20 | 2010-11-25 | Monsanto Technology Llc | Methods and compositions for selecting an improved plant |
| WO2010147804A1 (fr) * | 2009-06-10 | 2010-12-23 | Wisconsin Alumni Research Foundation | Méthode de réparation de cassure double brin d'adn in vitro et applications afférentes |
| NO329699B1 (no) * | 2009-06-16 | 2010-12-06 | Agr Cannseal As | Brønnverktøy og fremgangsmåte for in situ innføring av et behandlingsfluid i et ringrom i en brønn |
| WO2011047223A1 (fr) | 2009-10-16 | 2011-04-21 | Monsanto Technology Llc | Procédés de détection d'un polynucléotide |
| GB0922097D0 (en) | 2009-12-17 | 2010-02-03 | Atlas Genetics Ltd | Microbial assay |
| WO2011106368A2 (fr) | 2010-02-23 | 2011-09-01 | Illumina, Inc. | Procédés d'amplification destinés à minimiser le biais spécifique de séquence |
| US9184099B2 (en) | 2010-10-04 | 2015-11-10 | The Board Of Trustees Of The Leland Stanford Junior University | Biosensor devices, systems and methods therefor |
| EP2625526B1 (fr) | 2010-10-04 | 2017-03-15 | Genapsys Inc. | Systèmes et procédés de réactions biologiques parallèles, réutilisables, automatiques |
| US9399217B2 (en) | 2010-10-04 | 2016-07-26 | Genapsys, Inc. | Chamber free nanoreactor system |
| CA2814532C (fr) | 2010-10-12 | 2021-07-27 | Monsanto Technology Llc | Plante et semence de soja correspondant a l'evenement transgenique mon87712 et procede pour les detecter |
| BR122021012776B1 (pt) | 2010-12-17 | 2022-08-16 | Monsanto Technology Llc | Método para melhorar a competência de uma célula de planta para transformação mediada por bactérias |
| US10172305B2 (en) | 2011-04-29 | 2019-01-08 | Monsanto Technology Llc | Diagnostic molecular markers for seed lot purity traits in soybeans |
| CA2834679C (fr) | 2011-05-02 | 2021-12-28 | Board Of Regents Of The University Of Nebraska | Methode de production d'une plante ayant des caracteristiques utiles en supprimant le gene msh1 |
| KR101940833B1 (ko) | 2011-05-27 | 2019-01-21 | 제납시스 인크. | 유전자 및 생물학적 분석을 위한 시스템 및 방법 |
| US8585973B2 (en) | 2011-05-27 | 2013-11-19 | The Board Of Trustees Of The Leland Stanford Junior University | Nano-sensor array |
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| US9701976B2 (en) | 2011-06-30 | 2017-07-11 | Monsanto Technology Llc | Alfalfa plant and seed corresponding to transgenic event KK 179-2 and methods for detection thereof |
| US9670540B2 (en) | 2011-07-21 | 2017-06-06 | Cornell University | Methods and devices for DNA sequencing and molecular diagnostics |
| HUE059863T2 (hu) | 2011-08-31 | 2023-01-28 | Seminis Vegetable Seeds Inc | Eljárás és készítmények görögdinnye keménységhez |
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| EP3257952B1 (fr) | 2012-09-11 | 2020-02-12 | Life Technologies Corporation | Amplification d'acides nucléiques |
| US10314253B2 (en) | 2012-12-04 | 2019-06-11 | Seminis Vegetable Seeds, Inc. | Methods and compositions for watermelon sex expression |
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| SG11201507261WA (en) | 2013-03-15 | 2015-10-29 | Theranos Inc | Nucleic acid amplification |
| US10450595B2 (en) | 2013-03-15 | 2019-10-22 | Theranos Ip Company, Llc | Nucleic acid amplification |
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| JP5847076B2 (ja) | 2009-05-20 | 2016-01-20 | バイオサイト インコーポレイテッド | Ｄｎａグリコシラーゼ／リアーゼおよびａｐエンドヌクレアーゼ基質 |
| WO2010141940A1 (fr) | 2009-06-05 | 2010-12-09 | Alere San Diego, Inc. | Réactifs et kits d'amplification par recombinase polymérase |
| CA3096342C (fr) | 2012-06-08 | 2023-04-04 | Ionian Technologies, Llc | Amplifications d'acide nucleique |
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2003
- 2003-02-21 DK DK03711216T patent/DK1499738T3/da active
- 2003-02-21 ES ES03711216T patent/ES2310237T3/es not_active Expired - Lifetime
- 2003-02-21 EP EP11184367.8A patent/EP2428588B1/fr not_active Expired - Lifetime
- 2003-02-21 AU AU2003215391A patent/AU2003215391B2/en not_active Expired
- 2003-02-21 JP JP2003571485A patent/JP4340543B2/ja not_active Expired - Lifetime
- 2003-02-21 PT PT03711216T patent/PT1499738E/pt unknown
- 2003-02-21 CA CA2476481A patent/CA2476481C/fr not_active Expired - Lifetime
- 2003-02-21 EP EP10180775.8A patent/EP2290096B1/fr not_active Expired - Lifetime
- 2003-02-21 EP EP08012222.9A patent/EP1992706B1/fr not_active Expired - Lifetime
- 2003-02-21 WO PCT/US2003/005492 patent/WO2003072805A2/fr not_active Ceased
- 2003-02-21 DE DE60322044T patent/DE60322044D1/de not_active Expired - Lifetime
- 2003-02-21 US US10/371,641 patent/US7270981B2/en not_active Expired - Lifetime
- 2003-02-21 EP EP03711216A patent/EP1499738B1/fr not_active Expired - Lifetime
- 2003-02-21 AT AT03711216T patent/ATE400663T1/de active
-
2007
- 2007-08-13 US US11/893,113 patent/US7485428B2/en not_active Expired - Lifetime
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2009
- 2009-01-30 US US12/322,354 patent/US20090325165A1/en not_active Abandoned
- 2009-02-06 JP JP2009026788A patent/JP4448188B2/ja not_active Expired - Lifetime
- 2009-12-07 JP JP2009278020A patent/JP5271244B2/ja not_active Expired - Lifetime
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2010
- 2010-04-30 US US12/799,786 patent/US20110065106A1/en not_active Abandoned
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2011
- 2011-07-28 US US13/192,806 patent/US8460875B2/en not_active Expired - Fee Related
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2012
- 2012-09-14 JP JP2012203178A patent/JP2012249637A/ja not_active Withdrawn
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2013
- 2013-06-06 US US13/911,268 patent/US9340825B2/en not_active Expired - Fee Related
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2016
- 2016-04-15 US US15/099,754 patent/US20170044598A1/en not_active Abandoned
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| US7763427B2 (en) | 2002-02-21 | 2010-07-27 | Twistdx, Inc. | Detection of recombinase polymerase amplification products |
| US8017339B2 (en) | 2002-02-21 | 2011-09-13 | Alere San Diego, Inc. | Compositions and kits for recombinase polymerase amplification |
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| US7666598B2 (en) | 2002-02-21 | 2010-02-23 | Twistdx, Inc. | Recombinase polymerase amplification |
| US8580507B2 (en) | 2005-07-25 | 2013-11-12 | Alere San Diego, Inc. | Methods for multiplexing recombinase polymerase amplification |
| US12577563B2 (en) | 2005-07-25 | 2026-03-17 | Abbott Diagnostics Scarborough, Inc. | Methods for multiplexing recombinase polymerase amplification |
| US9932577B2 (en) | 2005-07-25 | 2018-04-03 | Alere San Diego, Inc. | Methods for multiplexing recombinase polymerase amplification |
| US11566244B2 (en) | 2005-07-25 | 2023-01-31 | Abbott Diagnostics Scarborough, Inc. | Methods for multiplexing recombinase polymerase amplification |
| US7435561B2 (en) * | 2005-07-25 | 2008-10-14 | Asm Scientific, Inc. | Methods for multiplexing recombinase polymerase amplification |
| US10538760B2 (en) | 2005-07-25 | 2020-01-21 | Alere San Diego, Inc. | Methods for multiplexing recombinase polymerase amplification |
| US12227773B2 (en) | 2006-05-04 | 2025-02-18 | Abbott Diagnostics Scarborough, Inc. | Recombinase polymerase amplification |
| US8637253B2 (en) | 2006-05-04 | 2014-01-28 | Alere San Diego, Inc. | Recombinase polymerase amplification |
| US11339382B2 (en) | 2006-05-04 | 2022-05-24 | Abbott Diagnostics Scarborough, Inc. | Recombinase polymerase amplification |
| US10093908B2 (en) | 2006-05-04 | 2018-10-09 | Alere San Diego, Inc. | Recombinase polymerase amplification |
| US9896719B2 (en) | 2009-05-20 | 2018-02-20 | Alere San Diego Inc. | DNA glycosylase/lyase and AP endonuclease substrates |
| US9057097B2 (en) | 2009-06-05 | 2015-06-16 | Alere San Diego Inc. | Recombinase polymerase amplification reagents and kits |
| US9719132B2 (en) | 2011-04-07 | 2017-08-01 | Alere San Diego Inc. | Monitoring recombinase polymerase amplification mixtures |
| US9157127B2 (en) | 2011-04-07 | 2015-10-13 | Alere San Diego Inc. | Monitoring recombinase polymerase amplification mixtures |
| US8809021B2 (en) | 2011-04-07 | 2014-08-19 | Alere San Diego Inc. | Monitoring recombinase polymerase amplification mixtures |
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