CA2542824C - Method of selectively assaying adiponectin multimers - Google Patents

Method of selectively assaying adiponectin multimers Download PDF

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Publication number
CA2542824C
CA2542824C CA2542824A CA2542824A CA2542824C CA 2542824 C CA2542824 C CA 2542824C CA 2542824 A CA2542824 A CA 2542824A CA 2542824 A CA2542824 A CA 2542824A CA 2542824 C CA2542824 C CA 2542824C
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CA
Canada
Prior art keywords
adiponectin
hmw
protease
lmw
mmw
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA2542824A
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English (en)
French (fr)
Other versions
CA2542824A1 (en
Inventor
Hiroyuki Ebinuma
Hirokazu Yago
Yuka Akimoto
Osamu Miyazaki
Takashi Kadowaki
Toshimasa Yamauchi
Kazuo Hara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Todai TLO Ltd
Sekisui Medical Co Ltd
Original Assignee
Todai TLO Ltd
Sekisui Medical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Todai TLO Ltd, Sekisui Medical Co Ltd filed Critical Todai TLO Ltd
Publication of CA2542824A1 publication Critical patent/CA2542824A1/en
Application granted granted Critical
Publication of CA2542824C publication Critical patent/CA2542824C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Endocrinology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA2542824A 2003-10-15 2004-10-15 Method of selectively assaying adiponectin multimers Expired - Lifetime CA2542824C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2003354930 2003-10-15
JP2003-354930 2003-10-15
PCT/JP2004/015260 WO2005038457A1 (ja) 2003-10-15 2004-10-15 多量体アディポネクチンの分別測定方法

Publications (2)

Publication Number Publication Date
CA2542824A1 CA2542824A1 (en) 2005-04-28
CA2542824C true CA2542824C (en) 2013-08-27

Family

ID=34463157

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2542824A Expired - Lifetime CA2542824C (en) 2003-10-15 2004-10-15 Method of selectively assaying adiponectin multimers

Country Status (12)

Country Link
US (2) US7608405B2 (de)
EP (2) EP1681566B1 (de)
JP (1) JP4677545B2 (de)
KR (1) KR101206338B1 (de)
CN (1) CN1867828B (de)
AT (2) ATE554385T1 (de)
AU (1) AU2004282754B9 (de)
CA (1) CA2542824C (de)
DE (1) DE602004022575D1 (de)
ES (2) ES2383259T3 (de)
MX (1) MXPA06004235A (de)
WO (1) WO2005038457A1 (de)

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CA2545065C (en) * 2003-11-07 2012-07-17 Merck & Co., Inc. Method of identifying responders to treatment with insulin sensitizers
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PL2289909T3 (pl) 2005-11-30 2015-04-30 Abbvie Inc Sposób przeszukiwania, proces oczyszczania niedyfundujących oligomerów Abeta, selektywne przeciwciała przeciw niedyfundującym oligomerom Abeta i sposób wytwarzania tych przeciwciał
RU2432362C2 (ru) 2005-11-30 2011-10-27 Эбботт Лэборетриз Моноклональные антитела и их применения
US8455626B2 (en) * 2006-11-30 2013-06-04 Abbott Laboratories Aβ conformer selective anti-aβ globulomer monoclonal antibodies
EP2124952A2 (de) 2007-02-27 2009-12-02 Abbott GmbH & Co. KG Verfahren zur behandlung von amyloidosen
CA2707182C (en) 2007-11-30 2017-12-12 Siemens Healthcare Diagnostics Inc. Adiponectin receptor fragments and methods of use
JP2011512813A (ja) 2008-02-29 2011-04-28 アイシス イノベーション リミテッド 診断法
JP5398697B2 (ja) 2008-02-29 2014-01-29 積水メディカル株式会社 高分子量アディポネクチンの測定方法
WO2009141352A2 (en) 2008-05-20 2009-11-26 F. Hoffmann-La Roche Ag Risk analysis in patients with and without metabolic syndrome
US9817001B2 (en) 2008-05-27 2017-11-14 Boston Heart Diagnostics Corporation Methods for determining LDL cholesterol treatment
WO2010123720A1 (en) 2009-04-23 2010-10-28 Siemens Healthcare Diagnostics Inc. Monomeric and dimeric forms of adiponectin receptor fragments and methods of use
JP2012502290A (ja) * 2008-09-11 2012-01-26 エフ．ホフマン−ラ ロシュ アーゲー メタボリックシンドロームを有する患者におけるナトリウム利尿ペプチドおよびアディポネクチン
US8470541B1 (en) 2008-09-27 2013-06-25 Boston Heart Diagnostics Corporation Methods for separation and immuno-detection of biomolecules, and apparatus related thereto
EP2353015A1 (de) * 2008-11-10 2011-08-10 F. Hoffmann-La Roche AG Relevanz der darmadipozytenfunktion bei typ-1-diabetes
EP2211182A1 (de) 2009-01-16 2010-07-28 Roche Diagnostics GmbH Verfahren zur Bewertung des Schweregrades einer Leberzirrhose
US8871518B2 (en) 2009-05-07 2014-10-28 Otsuka Pharmaceutical Co., Ltd. Monoclonal antibody for analyzing high-molecular weight adiponectin and utilization of same
ES2684475T3 (es) 2010-04-15 2018-10-03 Abbvie Inc. Proteínas que se unen a beta amiloide
JP5685777B2 (ja) * 2010-04-28 2015-03-18 株式会社エヌビィー健康研究所 バーチャルウエスタンブロッティングシステム
JP5555374B2 (ja) 2010-06-15 2014-07-23 エフ．ホフマン−ラ ロシュ アーゲー 外科処置後の急性腎傷害の予測および認識
CN103298833B (zh) 2010-08-14 2015-12-16 Abbvie公司 β淀粉样蛋白结合蛋白
EP2392927A1 (de) 2011-03-11 2011-12-07 F. Hoffmann-La Roche AG Diagnose von Stoffwechselstörungen in HIV-infizierten Patienten
EP2385372A1 (de) 2011-06-21 2011-11-09 Roche Diagnostics GmbH Nierenerkrankung in einer normal und nicht normal verlaufenden Schwangerschaft
EP2568291A1 (de) 2011-09-07 2013-03-13 Roche Diagnostics GmbH L-FABP-basierte Diagnose eines Nierentraumas nach einem akuten Ereignis oder nach einem chirurgischen Eingriff
US8765377B2 (en) 2011-10-13 2014-07-01 Boston Heart Diagnostics Corporation Compositions and methods for treating and preventing coronary heart disease
CN104737020B (zh) * 2012-08-30 2016-08-17 希森美康株式会社 早期肾障碍的评价指标和其测定方法
US20140120559A1 (en) 2012-10-26 2014-05-01 Boston Heart Diagnostics Corporation Diabetes panel
US9828624B2 (en) 2013-07-24 2017-11-28 Boston Heart Diagnostics Corporation Driving patient compliance with therapy
JP6512590B2 (ja) * 2014-08-25 2019-05-15 メカノジェニック株式会社 メタボリックシンドローム発症の危険性の予測方法
CA2968221A1 (en) 2014-11-17 2016-05-26 Boston Heart Diagnostic Corporation Cardiovascular disease risk assessment
HUE051783T2 (hu) * 2015-07-07 2021-03-29 Seqirus Uk Ltd Eljárás immunogén hemagglutinin mennyiségi meghatározására
CN117054645A (zh) 2016-09-06 2023-11-14 富士瑞必欧株式会社 甲状腺球蛋白的测定方法及测定试剂
EP3514539B1 (de) 2016-09-13 2024-11-20 Fujirebio Inc. Testverfahren und testreagens für herztroponin
US20220196637A1 (en) 2019-05-24 2022-06-23 Fujirebio Inc. Method and reagent for measuring thyroglobulin
WO2021060450A1 (ja) 2019-09-27 2021-04-01 富士レビオ株式会社 Ｂ型肝炎ウイルスコア関連抗原のイムノアッセイ及びそのためのキット
CN111239421A (zh) * 2020-02-19 2020-06-05 安徽大千生物工程有限公司 一种定量检测脂联素adpn的胶乳增强免疫比浊试剂盒及其制备与应用方法
US20230160912A1 (en) 2020-03-31 2023-05-25 Fujirebio Inc. Method for immunoassay of amyloid beta in blood, and kit for same
CN111892907B (zh) * 2020-07-15 2021-11-02 广东省医疗器械研究所 一种白蛋白胶粘剂及其制备方法
JPWO2023013725A1 (de) 2021-08-06 2023-02-09

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Publication number Priority date Publication date Assignee Title
US4444879A (en) * 1981-01-29 1984-04-24 Science Research Center, Inc. Immunoassay with article having support film and immunological counterpart of analyte
JP4424775B2 (ja) 1999-04-21 2010-03-03 大塚製薬株式会社 抗原蛋白質の検出方法
CN1281981A (zh) * 1999-07-26 2001-01-31 武汉埃克玛生物技术有限公司 血清低密度脂蛋白测定试剂
CN1111201C (zh) * 1999-11-04 2003-06-11 孙续国 低密度脂蛋白受体检测试剂及方法
JP4458622B2 (ja) 2000-05-26 2010-04-28 積水メディカル株式会社 免疫学的測定方法及び測定用試薬
JP4547696B2 (ja) 2001-06-07 2010-09-22 第一三共株式会社 肝硬変予防・治療剤
ATE504001T1 (de) * 2001-08-17 2011-04-15 Fujirebio Kk Verfahren zur diagnose oder überwachung eines fehlers im zuckerstoffwechsel

Also Published As

Publication number Publication date
EP1681566A1 (de) 2006-07-19
EP2071333B1 (de) 2012-04-18
CN1867828A (zh) 2006-11-22
KR20060132571A (ko) 2006-12-21
EP2071333A3 (de) 2009-07-08
AU2004282754B2 (en) 2009-11-12
EP2071333A2 (de) 2009-06-17
EP1681566A4 (de) 2007-05-02
KR101206338B1 (ko) 2012-12-03
US8039223B2 (en) 2011-10-18
ES2383259T3 (es) 2012-06-19
US7608405B2 (en) 2009-10-27
US20070042424A1 (en) 2007-02-22
EP1681566B1 (de) 2009-08-12
WO2005038457A1 (ja) 2005-04-28
JPWO2005038457A1 (ja) 2007-01-18
ES2329582T3 (es) 2009-11-27
ATE439590T1 (de) 2009-08-15
AU2004282754B9 (en) 2009-12-10
CN1867828B (zh) 2010-09-29
ATE554385T1 (de) 2012-05-15
DE602004022575D1 (de) 2009-09-24
CA2542824A1 (en) 2005-04-28
AU2004282754A1 (en) 2005-04-28
US20090291461A1 (en) 2009-11-26
MXPA06004235A (es) 2007-02-14
JP4677545B2 (ja) 2011-04-27

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