CA2619217A1 - Neurorestoration with r(+) pramipexole - Google Patents

Neurorestoration with r(+) pramipexole Download PDF

Info

Publication number: CA2619217A1
Authority: CA; Canada
Prior art keywords: pramipexole; formulation; enantiomer; daily; tetrahydrobenzathiazole
Prior art date: 2005-08-15
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

CA002619217A

Other languages

English (en)

French (fr)

Inventor

James P. Bennett, Jr.

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

UVA Licensing and Ventures Group

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-08-15

Filing date

2006-08-15

Publication date

2007-02-22

2006-08-15 Application filed by Individual filed Critical Individual

2007-02-22 Publication of CA2619217A1 publication Critical patent/CA2619217A1/en

Status Abandoned legal-status Critical Current

Links

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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Epidemiology (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Ophthalmology & Optometry (AREA)
Biochemistry (AREA)
Toxicology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

CA002619217A 2005-08-15 2006-08-15 Neurorestoration with r(+) pramipexole Abandoned CA2619217A1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US70821305P	2005-08-15	2005-08-15
US60/708,213		2005-08-15
PCT/US2006/031831 WO2007022182A1 (en)	2005-08-15	2006-08-15	Neurorestoration with r(+) pramipexole

Publications (1)

Publication Number	Publication Date
CA2619217A1 true CA2619217A1 (en)	2007-02-22

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ID=37428609

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002619217A Abandoned CA2619217A1 (en)	2005-08-15	2006-08-15	Neurorestoration with r(+) pramipexole

Country Status (10)

Country	Link
US (3)	US20080234338A1 (2)
EP (1)	EP1917014B1 (2)
JP (2)	JP2009504748A (2)
AT (1)	ATE444750T1 (2)
AU (1)	AU2006279643B2 (2)
CA (1)	CA2619217A1 (2)
DE (1)	DE602006009670D1 (2)
ES (1)	ES2334061T3 (2)
IL (1)	IL189512A (2)
WO (1)	WO2007022182A1 (2)

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US8518926B2 (en)	2006-04-10	2013-08-27	Knopp Neurosciences, Inc.	Compositions and methods of using (R)-pramipexole
US8524695B2 (en)	2006-12-14	2013-09-03	Knopp Neurosciences, Inc.	Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same
US9468630B2 (en)	2013-07-12	2016-10-18	Knopp Biosciences Llc	Compositions and methods for treating conditions related to increased eosinophils
US9512096B2 (en)	2011-12-22	2016-12-06	Knopp Biosciences, LLP	Synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds
US9642840B2 (en)	2013-08-13	2017-05-09	Knopp Biosciences, Llc	Compositions and methods for treating plasma cell disorders and B-cell prolymphocytic disorders
US9662313B2 (en)	2013-02-28	2017-05-30	Knopp Biosciences Llc	Compositions and methods for treating amyotrophic lateral sclerosis in responders
US9763918B2 (en)	2013-08-13	2017-09-19	Knopp Biosciences Llc	Compositions and methods for treating chronic urticaria
US9849116B2 (en)	2008-08-19	2017-12-26	Knopp Biosciences Llc	Compositions and methods of using (R)-pramipexole
US10179774B2 (en)	2007-03-14	2019-01-15	Knopp Biosciences Llc	Synthesis of chirally purified substituted benzothiazole diamines
US10383857B2 (en)	2013-07-12	2019-08-20	Knopp Biosciences Llc	Compositions and methods for treating conditions related to elevated levels of eosinophils and/or basophils

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2006
- 2006-08-15 AT AT06801521T patent/ATE444750T1/de not_active IP Right Cessation
- 2006-08-15 AU AU2006279643A patent/AU2006279643B2/en not_active Ceased
- 2006-08-15 DE DE602006009670T patent/DE602006009670D1/de active Active
- 2006-08-15 CA CA002619217A patent/CA2619217A1/en not_active Abandoned
- 2006-08-15 WO PCT/US2006/031831 patent/WO2007022182A1/en not_active Ceased
- 2006-08-15 ES ES06801521T patent/ES2334061T3/es active Active
- 2006-08-15 JP JP2008527061A patent/JP2009504748A/ja not_active Withdrawn
- 2006-08-15 EP EP06801521A patent/EP1917014B1/en not_active Not-in-force
- 2006-08-15 US US12/063,943 patent/US20080234338A1/en not_active Abandoned
2008
- 2008-02-13 IL IL189512A patent/IL189512A/en not_active IP Right Cessation
2011
- 2011-05-06 US US13/102,757 patent/US20110218222A1/en not_active Abandoned
2012
- 2012-10-23 JP JP2012233610A patent/JP2013014629A/ja active Pending
- 2012-12-27 US US13/728,504 patent/US20130116292A1/en not_active Abandoned

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US8524695B2 (en)	2006-12-14	2013-09-03	Knopp Neurosciences, Inc.	Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same
US10179774B2 (en)	2007-03-14	2019-01-15	Knopp Biosciences Llc	Synthesis of chirally purified substituted benzothiazole diamines
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US10208003B2 (en)	2011-12-22	2019-02-19	Knopp Biosciences Llc	Synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds
US9512096B2 (en)	2011-12-22	2016-12-06	Knopp Biosciences, LLP	Synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds
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ATE444750T1 (de)	2009-10-15
ES2334061T3 (es)	2010-03-04
AU2006279643B2 (en)	2010-06-17
EP1917014B1 (en)	2009-10-07
US20110218222A1 (en)	2011-09-08
IL189512A0 (en)	2011-08-01
IL189512A (en)	2013-03-24
WO2007022182A1 (en)	2007-02-22
JP2013014629A (ja)	2013-01-24
JP2009504748A (ja)	2009-02-05
DE602006009670D1 (de)	2009-11-19
EP1917014A1 (en)	2008-05-07
US20080234338A1 (en)	2008-09-25
US20130116292A1 (en)	2013-05-09

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