CA2651002A1 - Nouvelles applications de l'escitalopram - Google Patents
Nouvelles applications de l'escitalopram Download PDFInfo
- Publication number
- CA2651002A1 CA2651002A1 CA002651002A CA2651002A CA2651002A1 CA 2651002 A1 CA2651002 A1 CA 2651002A1 CA 002651002 A CA002651002 A CA 002651002A CA 2651002 A CA2651002 A CA 2651002A CA 2651002 A1 CA2651002 A1 CA 2651002A1
- Authority
- CA
- Canada
- Prior art keywords
- condition
- use according
- escitalopram
- medicament
- unit dose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- WSEQXVZVJXJVFP-FQEVSTJZSA-N escitalopram Chemical compound C1([C@]2(C3=CC=C(C=C3CO2)C#N)CCCN(C)C)=CC=C(F)C=C1 WSEQXVZVJXJVFP-FQEVSTJZSA-N 0.000 title claims abstract description 69
- 229960004341 escitalopram Drugs 0.000 title claims abstract description 67
- 230000019771 cognition Effects 0.000 title claims abstract description 50
- 239000003814 drug Substances 0.000 claims abstract description 26
- 230000003292 diminished effect Effects 0.000 claims abstract description 25
- 238000002360 preparation method Methods 0.000 claims abstract description 23
- 150000001875 compounds Chemical class 0.000 claims abstract description 22
- 150000003839 salts Chemical class 0.000 claims abstract description 21
- 238000011282 treatment Methods 0.000 claims description 22
- 238000000034 method Methods 0.000 claims description 21
- 206010012289 Dementia Diseases 0.000 claims description 18
- 208000028173 post-traumatic stress disease Diseases 0.000 claims description 17
- 201000000980 schizophrenia Diseases 0.000 claims description 13
- 208000006096 Attention Deficit Disorder with Hyperactivity Diseases 0.000 claims description 12
- 239000000164 antipsychotic agent Substances 0.000 claims description 12
- 208000024827 Alzheimer disease Diseases 0.000 claims description 11
- 230000000561 anti-psychotic effect Effects 0.000 claims description 11
- 229960001534 risperidone Drugs 0.000 claims description 11
- RAPZEAPATHNIPO-UHFFFAOYSA-N risperidone Chemical compound FC1=CC=C2C(C3CCN(CC3)CCC=3C(=O)N4CCCCC4=NC=3C)=NOC2=C1 RAPZEAPATHNIPO-UHFFFAOYSA-N 0.000 claims description 11
- BGRJTUBHPOOWDU-NSHDSACASA-N (S)-(-)-sulpiride Chemical compound CCN1CCC[C@H]1CNC(=O)C1=CC(S(N)(=O)=O)=CC=C1OC BGRJTUBHPOOWDU-NSHDSACASA-N 0.000 claims description 10
- 208000019901 Anxiety disease Diseases 0.000 claims description 10
- 208000018737 Parkinson disease Diseases 0.000 claims description 10
- LNEPOXFFQSENCJ-UHFFFAOYSA-N haloperidol Chemical compound C1CC(O)(C=2C=CC(Cl)=CC=2)CCN1CCCC(=O)C1=CC=C(F)C=C1 LNEPOXFFQSENCJ-UHFFFAOYSA-N 0.000 claims description 10
- WEIMMECSAQVSGO-UHFFFAOYSA-N n-(3-hydroxy-4-propylphenyl)acetamide Chemical compound CCCC1=CC=C(NC(C)=O)C=C1O WEIMMECSAQVSGO-UHFFFAOYSA-N 0.000 claims description 10
- 238000002560 therapeutic procedure Methods 0.000 claims description 10
- WFPIAZLQTJBIFN-DVZOWYKESA-N zuclopenthixol Chemical compound C1CN(CCO)CCN1CC\C=C\1C2=CC(Cl)=CC=C2SC2=CC=CC=C2/1 WFPIAZLQTJBIFN-DVZOWYKESA-N 0.000 claims description 10
- 229940123445 Tricyclic antidepressant Drugs 0.000 claims description 9
- 229940049706 benzodiazepine Drugs 0.000 claims description 9
- 150000001557 benzodiazepines Chemical class 0.000 claims description 9
- 206010027175 memory impairment Diseases 0.000 claims description 9
- 239000003029 tricyclic antidepressant agent Substances 0.000 claims description 9
- 208000030507 AIDS Diseases 0.000 claims description 8
- 208000024714 major depressive disease Diseases 0.000 claims description 8
- 229960004170 clozapine Drugs 0.000 claims description 7
- QZUDBNBUXVUHMW-UHFFFAOYSA-N clozapine Chemical compound C1CN(C)CCN1C1=NC2=CC(Cl)=CC=C2NC2=CC=CC=C12 QZUDBNBUXVUHMW-UHFFFAOYSA-N 0.000 claims description 7
- 229960005017 olanzapine Drugs 0.000 claims description 7
- KVWDHTXUZHCGIO-UHFFFAOYSA-N olanzapine Chemical compound C1CN(C)CCN1C1=NC2=CC=CC=C2NC2=C1C=C(C)S2 KVWDHTXUZHCGIO-UHFFFAOYSA-N 0.000 claims description 7
- 229960004431 quetiapine Drugs 0.000 claims description 7
- URKOMYMAXPYINW-UHFFFAOYSA-N quetiapine Chemical compound C1CN(CCOCCO)CCN1C1=NC2=CC=CC=C2SC2=CC=CC=C12 URKOMYMAXPYINW-UHFFFAOYSA-N 0.000 claims description 7
- 229960000652 sertindole Drugs 0.000 claims description 7
- GZKLJWGUPQBVJQ-UHFFFAOYSA-N sertindole Chemical compound C1=CC(F)=CC=C1N1C2=CC=C(Cl)C=C2C(C2CCN(CCN3C(NCC3)=O)CC2)=C1 GZKLJWGUPQBVJQ-UHFFFAOYSA-N 0.000 claims description 7
- BABFYCSPNDKXRI-UHFFFAOYSA-N 2-[4-[3-(2-chlorophenothiazin-10-yl)propyl]piperazin-1-yl]ethyl 4-aminobutanoate Chemical compound C1CN(CCOC(=O)CCCN)CCN1CCCN1C2=CC(Cl)=CC=C2SC2=CC=CC=C21 BABFYCSPNDKXRI-UHFFFAOYSA-N 0.000 claims description 6
- PMXMIIMHBWHSKN-UHFFFAOYSA-N 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one Chemical compound FC1=CC=C2C(C3CCN(CC3)CCC=3C(=O)N4CCCC(O)C4=NC=3C)=NOC2=C1 PMXMIIMHBWHSKN-UHFFFAOYSA-N 0.000 claims description 6
- CYGODHVAJQTCBG-UHFFFAOYSA-N Bifeprunox Chemical compound C=12OC(=O)NC2=CC=CC=1N(CC1)CCN1CC(C=1)=CC=CC=1C1=CC=CC=C1 CYGODHVAJQTCBG-UHFFFAOYSA-N 0.000 claims description 6
- ZZQNEJILGNNOEP-UHFFFAOYSA-N Ocaperidone Chemical compound FC1=CC=C2C(C3CCN(CC3)CCC3=C(C)N=C4N(C3=O)C=CC=C4C)=NOC2=C1 ZZQNEJILGNNOEP-UHFFFAOYSA-N 0.000 claims description 6
- 229950009087 bifeprunox Drugs 0.000 claims description 6
- 229960003162 iloperidone Drugs 0.000 claims description 6
- XMXHEBAFVSFQEX-UHFFFAOYSA-N iloperidone Chemical compound COC1=CC(C(C)=O)=CC=C1OCCCN1CCC(C=2C3=CC=C(F)C=C3ON=2)CC1 XMXHEBAFVSFQEX-UHFFFAOYSA-N 0.000 claims description 6
- 229960001432 lurasidone Drugs 0.000 claims description 6
- PQXKDMSYBGKCJA-CVTJIBDQSA-N lurasidone Chemical compound C1=CC=C2C(N3CCN(CC3)C[C@@H]3CCCC[C@H]3CN3C(=O)[C@@H]4[C@H]5CC[C@H](C5)[C@@H]4C3=O)=NSC2=C1 PQXKDMSYBGKCJA-CVTJIBDQSA-N 0.000 claims description 6
- 229950010634 ocaperidone Drugs 0.000 claims description 6
- 229960001057 paliperidone Drugs 0.000 claims description 6
- 238000001671 psychotherapy Methods 0.000 claims description 6
- 229960000607 ziprasidone Drugs 0.000 claims description 6
- MVWVFYHBGMAFLY-UHFFFAOYSA-N ziprasidone Chemical compound C1=CC=C2C(N3CCN(CC3)CCC3=CC=4CC(=O)NC=4C=C3Cl)=NSC2=C1 MVWVFYHBGMAFLY-UHFFFAOYSA-N 0.000 claims description 6
- VSWBSWWIRNCQIJ-GJZGRUSLSA-N (R,R)-asenapine Chemical compound O1C2=CC=CC=C2[C@@H]2CN(C)C[C@H]2C2=CC(Cl)=CC=C21 VSWBSWWIRNCQIJ-GJZGRUSLSA-N 0.000 claims description 5
- WSPOMRSOLSGNFJ-AUWJEWJLSA-N (Z)-chlorprothixene Chemical compound C1=C(Cl)C=C2C(=C/CCN(C)C)\C3=CC=CC=C3SC2=C1 WSPOMRSOLSGNFJ-AUWJEWJLSA-N 0.000 claims description 5
- PXUIZULXJVRBPC-UHFFFAOYSA-N 1'-[3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl]hexahydro-2H-spiro[imidazo[1,2-a]pyridine-3,4'-piperidin]-2-one Chemical compound C12=CC(Cl)=CC=C2CCC2=CC=CC=C2N1CCCN1CCC2(C(NC3CCCCN32)=O)CC1 PXUIZULXJVRBPC-UHFFFAOYSA-N 0.000 claims description 5
- DKMFBWQBDIGMHM-UHFFFAOYSA-N 1-(4-fluorophenyl)-4-(4-methyl-1-piperidinyl)-1-butanone Chemical compound C1CC(C)CCN1CCCC(=O)C1=CC=C(F)C=C1 DKMFBWQBDIGMHM-UHFFFAOYSA-N 0.000 claims description 5
- MDLAAYDRRZXJIF-UHFFFAOYSA-N 1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]-4-piperidinol Chemical compound C1CC(O)(C=2C=C(C(Cl)=CC=2)C(F)(F)F)CCN1CCCC(C=1C=CC(F)=CC=1)C1=CC=C(F)C=C1 MDLAAYDRRZXJIF-UHFFFAOYSA-N 0.000 claims description 5
- FEBOTPHFXYHVPL-UHFFFAOYSA-N 3-[1-[4-(4-fluorophenyl)-4-oxobutyl]-4-piperidinyl]-1H-benzimidazol-2-one Chemical compound C1=CC(F)=CC=C1C(=O)CCCN1CCC(N2C(NC3=CC=CC=C32)=O)CC1 FEBOTPHFXYHVPL-UHFFFAOYSA-N 0.000 claims description 5
- GUJRSXAPGDDABA-NSHDSACASA-N 3-bromo-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2,6-dimethoxybenzamide Chemical compound CCN1CCC[C@H]1CNC(=O)C1=C(OC)C=CC(Br)=C1OC GUJRSXAPGDDABA-NSHDSACASA-N 0.000 claims description 5
- BIAVGWDGIJKWRM-FQEVSTJZSA-N 3-hydroxy-2-phenyl-n-[(1s)-1-phenylpropyl]quinoline-4-carboxamide Chemical compound N([C@@H](CC)C=1C=CC=CC=1)C(=O)C(C1=CC=CC=C1N=1)=C(O)C=1C1=CC=CC=C1 BIAVGWDGIJKWRM-FQEVSTJZSA-N 0.000 claims description 5
- QOYHHIBFXOOADH-UHFFFAOYSA-N 8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one Chemical compound C1=CC(F)=CC=C1C(C=1C=CC(F)=CC=1)CCCN1CCC2(C(NCN2C=2C=CC=CC=2)=O)CC1 QOYHHIBFXOOADH-UHFFFAOYSA-N 0.000 claims description 5
- ILMHNKKMKWQVCE-UHFFFAOYSA-N 8-fluoro-12-(4-methylpiperazin-1-yl)-6h-[1]benzothiolo[2,3-b][1,5]benzodiazepine Chemical compound C1CN(C)CCN1C1=NC2=CC=C(F)C=C2NC2=C1C1=CC=CC=C1S2 ILMHNKKMKWQVCE-UHFFFAOYSA-N 0.000 claims description 5
- CEUORZQYGODEFX-UHFFFAOYSA-N Aripirazole Chemical compound ClC1=CC=CC(N2CCN(CCCCOC=3C=C4NC(=O)CCC4=CC=3)CC2)=C1Cl CEUORZQYGODEFX-UHFFFAOYSA-N 0.000 claims description 5
- XVGOZDAJGBALKS-UHFFFAOYSA-N Blonanserin Chemical compound C1CN(CC)CCN1C1=CC(C=2C=CC(F)=CC=2)=C(CCCCCC2)C2=N1 XVGOZDAJGBALKS-UHFFFAOYSA-N 0.000 claims description 5
- RKLNONIVDFXQRX-UHFFFAOYSA-N Bromperidol Chemical compound C1CC(O)(C=2C=CC(Br)=CC=2)CCN1CCCC(=O)C1=CC=C(F)C=C1 RKLNONIVDFXQRX-UHFFFAOYSA-N 0.000 claims description 5
- KAAZGXDPUNNEFN-UHFFFAOYSA-N Clotiapine Chemical compound C1CN(C)CCN1C1=NC2=CC=CC=C2SC2=CC=C(Cl)C=C12 KAAZGXDPUNNEFN-UHFFFAOYSA-N 0.000 claims description 5
- PLDUPXSUYLZYBN-UHFFFAOYSA-N Fluphenazine Chemical compound C1CN(CCO)CCN1CCCN1C2=CC(C(F)(F)F)=CC=C2SC2=CC=CC=C21 PLDUPXSUYLZYBN-UHFFFAOYSA-N 0.000 claims description 5
- KLPWJLBORRMFGK-UHFFFAOYSA-N Molindone Chemical compound O=C1C=2C(CC)=C(C)NC=2CCC1CN1CCOCC1 KLPWJLBORRMFGK-UHFFFAOYSA-N 0.000 claims description 5
- JTVPZMFULRWINT-UHFFFAOYSA-N N-[2-(diethylamino)ethyl]-2-methoxy-5-methylsulfonylbenzamide Chemical compound CCN(CC)CCNC(=O)C1=CC(S(C)(=O)=O)=CC=C1OC JTVPZMFULRWINT-UHFFFAOYSA-N 0.000 claims description 5
- JNNOSTQEZICQQP-UHFFFAOYSA-N N-desmethylclozapine Chemical compound N=1C2=CC(Cl)=CC=C2NC2=CC=CC=C2C=1N1CCNCC1 JNNOSTQEZICQQP-UHFFFAOYSA-N 0.000 claims description 5
- XCWPUUGSGHNIDZ-UHFFFAOYSA-N Oxypertine Chemical compound C1=2C=C(OC)C(OC)=CC=2NC(C)=C1CCN(CC1)CCN1C1=CC=CC=C1 XCWPUUGSGHNIDZ-UHFFFAOYSA-N 0.000 claims description 5
- RGCVKNLCSQQDEP-UHFFFAOYSA-N Perphenazine Chemical compound C1CN(CCO)CCN1CCCN1C2=CC(Cl)=CC=C2SC2=CC=CC=C21 RGCVKNLCSQQDEP-UHFFFAOYSA-N 0.000 claims description 5
- ZGUGWUXLJSTTMA-UHFFFAOYSA-N Promazinum Chemical compound C1=CC=C2N(CCCN(C)C)C3=CC=CC=C3SC2=C1 ZGUGWUXLJSTTMA-UHFFFAOYSA-N 0.000 claims description 5
- 208000028017 Psychotic disease Diseases 0.000 claims description 5
- UNRHXEPDKXPRTM-UHFFFAOYSA-N Sultopride Chemical compound CCN1CCCC1CNC(=O)C1=CC(S(=O)(=O)CC)=CC=C1OC UNRHXEPDKXPRTM-UHFFFAOYSA-N 0.000 claims description 5
- KLBQZWRITKRQQV-UHFFFAOYSA-N Thioridazine Chemical compound C12=CC(SC)=CC=C2SC2=CC=CC=C2N1CCC1CCCCN1C KLBQZWRITKRQQV-UHFFFAOYSA-N 0.000 claims description 5
- GFBKORZTTCHDGY-UWVJOHFNSA-N Thiothixene Chemical compound C12=CC(S(=O)(=O)N(C)C)=CC=C2SC2=CC=CC=C2\C1=C\CCN1CCN(C)CC1 GFBKORZTTCHDGY-UWVJOHFNSA-N 0.000 claims description 5
- 229960005054 acepromazine Drugs 0.000 claims description 5
- NOSIYYJFMPDDSA-UHFFFAOYSA-N acepromazine Chemical compound C1=C(C(C)=O)C=C2N(CCCN(C)C)C3=CC=CC=C3SC2=C1 NOSIYYJFMPDDSA-UHFFFAOYSA-N 0.000 claims description 5
- 229960000276 acetophenazine Drugs 0.000 claims description 5
- WNTYBHLDCKXEOT-UHFFFAOYSA-N acetophenazine Chemical compound C12=CC(C(=O)C)=CC=C2SC2=CC=CC=C2N1CCCN1CCN(CCO)CC1 WNTYBHLDCKXEOT-UHFFFAOYSA-N 0.000 claims description 5
- 101150109352 acr-16 gene Proteins 0.000 claims description 5
- 229960003036 amisulpride Drugs 0.000 claims description 5
- NTJOBXMMWNYJFB-UHFFFAOYSA-N amisulpride Chemical compound CCN1CCCC1CNC(=O)C1=CC(S(=O)(=O)CC)=C(N)C=C1OC NTJOBXMMWNYJFB-UHFFFAOYSA-N 0.000 claims description 5
- 229960004372 aripiprazole Drugs 0.000 claims description 5
- 229960005245 asenapine Drugs 0.000 claims description 5
- 229960002507 benperidol Drugs 0.000 claims description 5
- 229950002871 blonanserin Drugs 0.000 claims description 5
- 229960004037 bromperidol Drugs 0.000 claims description 5
- 229960000608 butaperazine Drugs 0.000 claims description 5
- DVLBYTMYSMAKHP-UHFFFAOYSA-N butaperazine Chemical compound C12=CC(C(=O)CCC)=CC=C2SC2=CC=CC=C2N1CCCN1CCN(C)CC1 DVLBYTMYSMAKHP-UHFFFAOYSA-N 0.000 claims description 5
- 229960005123 cariprazine Drugs 0.000 claims description 5
- KPWSJANDNDDRMB-QAQDUYKDSA-N cariprazine Chemical compound C1C[C@@H](NC(=O)N(C)C)CC[C@@H]1CCN1CCN(C=2C(=C(Cl)C=CC=2)Cl)CC1 KPWSJANDNDDRMB-QAQDUYKDSA-N 0.000 claims description 5
- 229960003030 chlorproethazine Drugs 0.000 claims description 5
- DBOUGBAQLIXZLV-UHFFFAOYSA-N chlorproethazine Chemical compound C1=C(Cl)C=C2N(CCCN(CC)CC)C3=CC=CC=C3SC2=C1 DBOUGBAQLIXZLV-UHFFFAOYSA-N 0.000 claims description 5
- 229960001076 chlorpromazine Drugs 0.000 claims description 5
- ZPEIMTDSQAKGNT-UHFFFAOYSA-N chlorpromazine Chemical compound C1=C(Cl)C=C2N(CCCN(C)C)C3=CC=CC=C3SC2=C1 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 0.000 claims description 5
- 229960001552 chlorprothixene Drugs 0.000 claims description 5
- NJMYODHXAKYRHW-DVZOWYKESA-N cis-flupenthixol Chemical compound C1CN(CCO)CCN1CC\C=C\1C2=CC(C(F)(F)F)=CC=C2SC2=CC=CC=C2/1 NJMYODHXAKYRHW-DVZOWYKESA-N 0.000 claims description 5
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- 229960003864 clotiapine Drugs 0.000 claims description 5
- 229960004278 cyamemazine Drugs 0.000 claims description 5
- SLFGIOIONGJGRT-UHFFFAOYSA-N cyamemazine Chemical compound C1=C(C#N)C=C2N(CC(CN(C)C)C)C3=CC=CC=C3SC2=C1 SLFGIOIONGJGRT-UHFFFAOYSA-N 0.000 claims description 5
- 229960005146 dixyrazine Drugs 0.000 claims description 5
- MSYUMPGNGDNTIQ-UHFFFAOYSA-N dixyrazine Chemical compound C12=CC=CC=C2SC2=CC=CC=C2N1CC(C)CN1CCN(CCOCCO)CC1 MSYUMPGNGDNTIQ-UHFFFAOYSA-N 0.000 claims description 5
- 229960000394 droperidol Drugs 0.000 claims description 5
- RMEDXOLNCUSCGS-UHFFFAOYSA-N droperidol Chemical compound C1=CC(F)=CC=C1C(=O)CCCN1CC=C(N2C(NC3=CC=CC=C32)=O)CC1 RMEDXOLNCUSCGS-UHFFFAOYSA-N 0.000 claims description 5
- 229960005220 fluanisone Drugs 0.000 claims description 5
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- YGKUEOZJFIXDGI-UHFFFAOYSA-N pridopidine Chemical compound C1CN(CCC)CCC1C1=CC=CC(S(C)(=O)=O)=C1 YGKUEOZJFIXDGI-UHFFFAOYSA-N 0.000 claims description 5
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- Psychology (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200600621 | 2006-05-02 | ||
| DKPA200600621 | 2006-05-02 | ||
| PCT/DK2007/050050 WO2007124757A2 (fr) | 2006-05-02 | 2007-04-30 | Nouvelles applications de l'escitalopram |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2651002A1 true CA2651002A1 (fr) | 2007-11-08 |
Family
ID=38134951
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002651002A Abandoned CA2651002A1 (fr) | 2006-05-02 | 2007-04-30 | Nouvelles applications de l'escitalopram |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP2026793A2 (fr) |
| JP (1) | JP2009535367A (fr) |
| KR (1) | KR20090009820A (fr) |
| CN (1) | CN101426494A (fr) |
| AR (1) | AR060732A1 (fr) |
| AU (1) | AU2007245983A1 (fr) |
| BR (1) | BRPI0710230A2 (fr) |
| CA (1) | CA2651002A1 (fr) |
| EA (1) | EA200870491A1 (fr) |
| IL (1) | IL194628A0 (fr) |
| MX (1) | MX2008013911A (fr) |
| NO (1) | NO20085009L (fr) |
| TW (1) | TW200812993A (fr) |
| WO (1) | WO2007124757A2 (fr) |
| ZA (1) | ZA200808632B (fr) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1535616B1 (fr) | 2002-08-22 | 2009-05-13 | Dainippon Sumitomo Pharma Co., Ltd. | Medicament destine au syndrome de la dysfonction d'integration |
| KR101113630B1 (ko) | 2003-06-23 | 2012-02-13 | 다이닛본 스미토모 세이야꾸 가부시끼가이샤 | 노인성 치매 치료제 |
| US20070160537A1 (en) | 2004-02-20 | 2007-07-12 | Takeo Ishiyama | In vivo screening method of therapeutic agent for memory/learning dysfunctions by schizophrenia |
| US20090036468A1 (en) * | 2007-08-03 | 2009-02-05 | Forest Laboratories Holdings Limited | Pharmaceutical compositions containing dopamine receptor ligands and methods of treatment using dopamine receptor ligands |
| EP2236138A1 (fr) * | 2009-03-30 | 2010-10-06 | PharmaNeuroBoost N.V. | Pipampèrone faible dose pour le traitement des troubles de l`anxiété et de l`humeur |
| US8258139B2 (en) * | 2010-11-08 | 2012-09-04 | Dainippon Sumitomo Pharma Co., Ltd. | Method of treatment for mental disorders |
| EP3069718A1 (fr) * | 2015-03-17 | 2016-09-21 | Universidade do Minho | Citalopram ou escitalopram destinés à être utilisés dans le traitement de maladies neurodégénératives |
| CN115813888A (zh) | 2016-12-20 | 2023-03-21 | 罗曼治疗系统股份公司 | 包含阿塞那平的透皮治疗系统 |
| EP3558276B1 (fr) | 2016-12-20 | 2024-11-06 | LTS Lohmann Therapie-Systeme AG | Système thérapeutique transdermique contenant de l'asénapine et du polysiloxane ou du polyisobutylène |
| WO2019002204A1 (fr) | 2017-06-26 | 2019-01-03 | Lts Lohmann Therapie-Systeme Ag | Système thérapeutique transdermique contenant de l'asénapine et un polymère hybride acrylique de type silicone |
| AU2019291060B2 (en) | 2018-06-20 | 2024-09-05 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system containing asenapine |
| US12329862B2 (en) | 2018-06-20 | 2025-06-17 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system containing asenapine |
| KR102051624B1 (ko) * | 2018-11-30 | 2019-12-02 | 아밀로이드솔루션 주식회사 | 트리플루프로마진 또는 이의 약학적으로 허용가능한 염을 유효성분으로 포함하는 퇴행성 뇌질환 치료용 약학 조성물 |
| CN109464436A (zh) * | 2019-01-10 | 2019-03-15 | 高智玉 | 西酞普兰或艾司西酞普兰分别和喹硫平联合在制备治疗精神障碍类疾病的复方制剂中的应用 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK213290D0 (da) * | 1990-09-06 | 1990-09-06 | Lundbeck & Co As H | Treatment of cerebrovascular disorders |
| SE9803157D0 (sv) * | 1998-09-16 | 1998-09-16 | Astra Ab | A new composition |
| SE9803158D0 (sv) * | 1998-09-16 | 1998-09-16 | Astra Ab | A new composition |
| US6617361B2 (en) * | 1999-11-05 | 2003-09-09 | Be Able, Llc | Behavior chemotherapy |
| ATE329620T1 (de) * | 2000-12-01 | 2006-07-15 | Be Able Llc | Verhaltenchemotherapie |
| WO2002076461A1 (fr) * | 2001-03-26 | 2002-10-03 | Serdar Murat Dursun | Combinaison de reboxetine et de citalopram |
| WO2002087566A1 (fr) * | 2001-05-01 | 2002-11-07 | H. Lundbeck A/S | Utilisation d'escitalopram pur enantiomere |
| US20050014848A1 (en) * | 2002-01-23 | 2005-01-20 | Pfizer Inc. | Combination of serotonin reuptake inhibitors and norephinephrine reuptake inhibitors |
| CA2529857A1 (fr) * | 2002-07-30 | 2004-02-05 | Peter Migaly | Combinaison de therapie pour la depression, la prevention du suicide et divers troubles medicaux et psychiatriques |
| AU2003287919B2 (en) * | 2002-12-23 | 2009-11-12 | H. Lundbeck A/S | Escitalopram hydrobromide and a method for the preparation thereof |
| WO2005023243A1 (fr) * | 2003-09-04 | 2005-03-17 | H. Lundbeck A/S | Combinaison d'un inhibiteur de recaptage de serotonine et de loxapine |
| JP2009511607A (ja) * | 2005-10-14 | 2009-03-19 | ハー・ルンドベック・アクチエゼルスカベット | エスシタロプラムおよびブプロピオンを含有する安定な医薬製剤 |
| EA200801081A1 (ru) * | 2005-10-14 | 2008-10-30 | Х. Лундбекк А/С | Способы лечения расстройств центральной нервной системы комбинацией малых доз эсциталопрама и бупропиона |
| US20070134322A1 (en) * | 2005-12-14 | 2007-06-14 | Forest Laboratories, Inc. | Modified and pulsatile release pharmaceutical formulations of escitalopram |
-
2007
- 2007-04-25 TW TW096114520A patent/TW200812993A/zh unknown
- 2007-04-30 KR KR1020087025797A patent/KR20090009820A/ko not_active Withdrawn
- 2007-04-30 AR ARP070101874A patent/AR060732A1/es unknown
- 2007-04-30 MX MX2008013911A patent/MX2008013911A/es not_active Application Discontinuation
- 2007-04-30 CN CNA200780014675XA patent/CN101426494A/zh active Pending
- 2007-04-30 AU AU2007245983A patent/AU2007245983A1/en not_active Abandoned
- 2007-04-30 JP JP2009508134A patent/JP2009535367A/ja not_active Withdrawn
- 2007-04-30 BR BRPI0710230-5A patent/BRPI0710230A2/pt not_active IP Right Cessation
- 2007-04-30 EA EA200870491A patent/EA200870491A1/ru unknown
- 2007-04-30 WO PCT/DK2007/050050 patent/WO2007124757A2/fr not_active Ceased
- 2007-04-30 EP EP07722705A patent/EP2026793A2/fr not_active Withdrawn
- 2007-04-30 CA CA002651002A patent/CA2651002A1/fr not_active Abandoned
-
2008
- 2008-10-07 IL IL194628A patent/IL194628A0/en unknown
- 2008-10-09 ZA ZA2008/08632A patent/ZA200808632B/en unknown
- 2008-12-02 NO NO20085009A patent/NO20085009L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CN101426494A (zh) | 2009-05-06 |
| IL194628A0 (en) | 2009-08-03 |
| KR20090009820A (ko) | 2009-01-23 |
| AR060732A1 (es) | 2008-07-10 |
| TW200812993A (en) | 2008-03-16 |
| ZA200808632B (en) | 2009-12-30 |
| AU2007245983A1 (en) | 2007-11-08 |
| WO2007124757A3 (fr) | 2008-07-24 |
| JP2009535367A (ja) | 2009-10-01 |
| WO2007124757A2 (fr) | 2007-11-08 |
| EP2026793A2 (fr) | 2009-02-25 |
| MX2008013911A (es) | 2008-11-12 |
| BRPI0710230A2 (pt) | 2011-08-02 |
| EA200870491A1 (ru) | 2009-04-28 |
| NO20085009L (no) | 2008-12-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |