CA2875342C - Sels de desfesoterodine - Google Patents

Sels de desfesoterodine Download PDF

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Publication number
CA2875342C
CA2875342C CA2875342A CA2875342A CA2875342C CA 2875342 C CA2875342 C CA 2875342C CA 2875342 A CA2875342 A CA 2875342A CA 2875342 A CA2875342 A CA 2875342A CA 2875342 C CA2875342 C CA 2875342C
Authority
CA
Canada
Prior art keywords
desfesoterodine
succinate
salt
salts
solid state
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2875342A
Other languages
English (en)
Other versions
CA2875342A1 (fr
Inventor
Simone EICHNER
Wolfgang Albrecht
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ratiopharm GmbH
Original Assignee
Ratiopharm GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ratiopharm GmbH filed Critical Ratiopharm GmbH
Publication of CA2875342A1 publication Critical patent/CA2875342A1/fr
Application granted granted Critical
Publication of CA2875342C publication Critical patent/CA2875342C/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/48—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
    • C07C215/54—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
    • C07C55/02—Dicarboxylic acids
    • C07C55/10—Succinic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La présente invention concerne des sels de desfésotérodine pratiquement purs, des sels de desfésotérodine, leurs formes à l'état solide et des compositions pharmaceutiques comprenant un ou plusieurs des sels de desfésotérodine et/ou de leurs formes à l'état solide.
CA2875342A 2012-06-14 2013-06-14 Sels de desfesoterodine Expired - Fee Related CA2875342C (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261659829P 2012-06-14 2012-06-14
US61/659,829 2012-06-14
US201361818135P 2013-05-01 2013-05-01
US61/818,135 2013-05-01
PCT/US2013/045992 WO2013188829A1 (fr) 2012-06-14 2013-06-14 Sels de desfésotérodine

Publications (2)

Publication Number Publication Date
CA2875342A1 CA2875342A1 (fr) 2013-12-19
CA2875342C true CA2875342C (fr) 2017-06-13

Family

ID=48808499

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2875342A Expired - Fee Related CA2875342C (fr) 2012-06-14 2013-06-14 Sels de desfesoterodine

Country Status (7)

Country Link
US (1) US9315450B2 (fr)
EP (1) EP2760822B1 (fr)
CA (1) CA2875342C (fr)
ES (1) ES2569201T3 (fr)
HR (1) HRP20160363T1 (fr)
PL (1) PL2760822T3 (fr)
WO (1) WO2013188829A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017137955A1 (fr) * 2016-02-14 2017-08-17 Celestis Pharmaceuticals Pvt. Ltd. Nouveau (r) et 3-(2-(allyloxy)-5-méthylphényl)-n,n-diisopropyl-3- phénylpropan-1-amine racémique et son utilisation pour la synthèse de (r) et de 2-(3- (diisopropylamino)-1-phénylpropyl)-4-(hydroxyméthyl)phénol racémique

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9203318D0 (sv) 1992-11-06 1992-11-06 Kabi Pharmacia Ab Novel 3,3-diphenylpropylamines, their use and preparation
EP0957073A1 (fr) 1998-05-12 1999-11-17 Schwarz Pharma Ag Dérivés de 3,3-diphénylpropylamines
DE10028443C1 (de) 2000-06-14 2002-05-29 Sanol Arznei Schwarz Gmbh Verfahren zur Herstellung von 3,3-Diarylpropylaminen, (R,S)- und (R)-4-Phenyl-2-chromanon-6-carbonsäure sowie (R)-4-Phenyl-2-chromanon-carbonsäure-cinchonidinsalz und deren Verwendung zur Herstellung eines rechtsdrehenden Hydroxybenzylalkohols und von pharmazeutischen Zusammensetzungen
ATE480531T1 (de) 2006-05-24 2010-09-15 Pfizer Ltd Verfahren zur herstellung von benzopyran-2- olderivaten
GB0813762D0 (en) 2008-07-28 2008-09-03 Moseley Darren C Slatted wall fixing element
PL2416761T3 (pl) 2009-05-11 2015-07-31 Ratiopharm Gmbh Desfezoterodyna w postaci soli kwasu winowego
WO2011158257A1 (fr) 2010-06-18 2011-12-22 Panacea Biotec Ltd Méthode de préparation de fesotérodine et d'intermédiaires

Also Published As

Publication number Publication date
HRP20160363T1 (hr) 2016-06-17
US9315450B2 (en) 2016-04-19
ES2569201T3 (es) 2016-05-09
EP2760822A1 (fr) 2014-08-06
PL2760822T3 (pl) 2016-09-30
EP2760822B1 (fr) 2016-03-23
CA2875342A1 (fr) 2013-12-19
WO2013188829A1 (fr) 2013-12-19
US20150152044A1 (en) 2015-06-04

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Legal Events

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EEER Examination request

Effective date: 20150330

MKLA Lapsed

Effective date: 20220301

MKLA Lapsed

Effective date: 20200831