CA2929166C - Anti-ccl17 antibodies - Google Patents

Anti-ccl17 antibodies Download PDF

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Publication number
CA2929166C
CA2929166C CA2929166A CA2929166A CA2929166C CA 2929166 C CA2929166 C CA 2929166C CA 2929166 A CA2929166 A CA 2929166A CA 2929166 A CA2929166 A CA 2929166A CA 2929166 C CA2929166 C CA 2929166C
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CA
Canada
Prior art keywords
antibody
seq
ccl17
human
nos
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2929166A
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English (en)
French (fr)
Other versions
CA2929166A1 (en
Inventor
Ken Boakye
Alfred Del Vecchio
John Kehoe
Eilyn Lacy
Lynne Murray
Mary Ryan
Sandra Santulli-Marotto
John Wheeler
Brian Whitaker
Alexey Teplyakov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Biotech Inc
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Janssen Biotech Inc
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Publication of CA2929166A1 publication Critical patent/CA2929166A1/en
Application granted granted Critical
Publication of CA2929166C publication Critical patent/CA2929166C/en
Active legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55522—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA2929166A 2013-11-06 2014-11-06 Anti-ccl17 antibodies Active CA2929166C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361900596P 2013-11-06 2013-11-06
US61/900,596 2013-11-06
PCT/US2014/064302 WO2015069865A1 (en) 2013-11-06 2014-11-06 Anti-ccl17 antibodies

Publications (2)

Publication Number Publication Date
CA2929166A1 CA2929166A1 (en) 2015-05-14
CA2929166C true CA2929166C (en) 2023-08-22

Family

ID=53007215

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2929166A Active CA2929166C (en) 2013-11-06 2014-11-06 Anti-ccl17 antibodies

Country Status (33)

Country Link
US (4) US9944697B2 (ko)
EP (2) EP3466445A1 (ko)
JP (1) JP6556742B2 (ko)
KR (1) KR102331054B1 (ko)
CN (1) CN105722531B (ko)
AU (1) AU2014346770B2 (ko)
BR (1) BR112016010071A2 (ko)
CA (1) CA2929166C (ko)
CL (1) CL2016001081A1 (ko)
CR (1) CR20160187A (ko)
CY (1) CY1124445T1 (ko)
DK (1) DK3065774T3 (ko)
DO (1) DOP2016000105A (ko)
EA (1) EA034655B1 (ko)
ES (1) ES2884255T3 (ko)
HR (1) HRP20211234T1 (ko)
HU (1) HUE058272T2 (ko)
IL (1) IL245488B (ko)
LT (1) LT3065774T (ko)
MA (1) MA39090B2 (ko)
MX (1) MX2016005982A (ko)
MY (1) MY192757A (ko)
NZ (2) NZ719506A (ko)
PE (1) PE20160856A1 (ko)
PH (1) PH12016500826B1 (ko)
PL (1) PL3065774T3 (ko)
PT (1) PT3065774T (ko)
RS (1) RS62373B1 (ko)
SG (1) SG11201603231XA (ko)
SI (1) SI3065774T1 (ko)
SM (1) SMT202100473T1 (ko)
UA (1) UA119973C2 (ko)
WO (1) WO2015069865A1 (ko)

Families Citing this family (7)

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CN108250290B (zh) * 2018-02-23 2024-03-12 上海捌加壹医药科技有限公司 Ccr4的n端重组蛋白及其用途
JP6979149B1 (ja) * 2020-07-10 2021-12-08 積水メディカル株式会社 Ｔａｒｃを含有する組成物、及びｔａｒｃの保存安定性向上方法
WO2024127277A1 (en) 2022-12-16 2024-06-20 Glaxosmithkline Intellectual Property Development Limited Method of treating pain with an anti-ccl17 antibody

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Also Published As

Publication number Publication date
WO2015069865A1 (en) 2015-05-14
CL2016001081A1 (es) 2016-10-21
KR20160077198A (ko) 2016-07-01
PT3065774T (pt) 2021-08-31
PH12016500826A1 (en) 2016-06-13
MA39090A1 (fr) 2018-03-30
EP3466445A1 (en) 2019-04-10
MX2016005982A (es) 2016-08-11
DOP2016000105A (es) 2016-10-31
DK3065774T3 (da) 2021-08-23
CA2929166A1 (en) 2015-05-14
US20150125458A1 (en) 2015-05-07
AU2014346770B2 (en) 2020-05-21
KR102331054B1 (ko) 2021-11-24
US11414484B2 (en) 2022-08-16
PE20160856A1 (es) 2016-09-03
SG11201603231XA (en) 2016-05-30
PL3065774T3 (pl) 2021-12-13
US20180171007A1 (en) 2018-06-21
LT3065774T (lt) 2021-09-10
IL245488A0 (en) 2016-06-30
SMT202100473T1 (it) 2021-09-14
HRP20211234T1 (hr) 2021-11-26
PH12016500826B1 (en) 2021-09-10
JP2016537024A (ja) 2016-12-01
US10829549B2 (en) 2020-11-10
UA119973C2 (uk) 2019-09-10
SI3065774T1 (sl) 2021-11-30
MY192757A (en) 2022-09-07
CN105722531A (zh) 2016-06-29
RS62373B1 (sr) 2021-10-29
EA034655B1 (ru) 2020-03-03
CY1124445T1 (el) 2022-07-22
EP3065774A4 (en) 2017-06-21
CR20160187A (es) 2016-08-04
JP6556742B2 (ja) 2019-08-07
BR112016010071A2 (pt) 2017-12-05
US20210017267A1 (en) 2021-01-21
EP3065774A1 (en) 2016-09-14
IL245488B (en) 2020-03-31
MA39090B2 (fr) 2021-10-29
NZ758354A (en) 2022-09-30
ES2884255T3 (es) 2021-12-10
EP3065774B1 (en) 2021-05-26
EA201690942A1 (ru) 2016-09-30
US9944697B2 (en) 2018-04-17
CN105722531B (zh) 2020-03-06
US20220348647A1 (en) 2022-11-03
HUE058272T2 (hu) 2022-07-28
NZ719506A (en) 2022-09-30

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