CA3043617A1 - Magl inhibitors - Google Patents

Magl inhibitors Download PDF

Info

Publication number: CA3043617A1
Authority: CA; Canada
Prior art keywords: compound; solvate; pharmaceutically acceptable; acceptable salt; formula
Prior art date: 2016-11-16
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

CA3043617A

Other languages

English (en)

French (fr)

Inventor

Cheryl A. Grice

Daniel J. Buzard

Michael B. SHAGHAFI

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

H Lundbeck AS

Original Assignee

Abide Therapeutics Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2016-11-16

Filing date

2017-11-15

Publication date

2018-05-24

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=62145825&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA3043617(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2017-11-15 Application filed by Abide Therapeutics Inc filed Critical Abide Therapeutics Inc

2018-05-24 Publication of CA3043617A1 publication Critical patent/CA3043617A1/en

Status Abandoned legal-status Critical Current

Links

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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Engineering & Computer Science (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Rheumatology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

CA3043617A 2016-11-16 2017-11-15 Magl inhibitors Abandoned CA3043617A1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US201662423102P	2016-11-16	2016-11-16
US62/423,102		2016-11-16
PCT/US2017/061870 WO2018093949A1 (en)	2016-11-16	2017-11-15	Magl inhibitors

Publications (1)

Publication Number	Publication Date
CA3043617A1 true CA3043617A1 (en)	2018-05-24

Family

ID=62145825

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA3043617A Abandoned CA3043617A1 (en)	2016-11-16	2017-11-15	Magl inhibitors

Country Status (27)

Country	Link
US (2)	US11059822B2 (2)
EP (1)	EP3541820B1 (2)
JP (1)	JP7042468B2 (2)
KR (1)	KR20190080935A (2)
CN (1)	CN110267962B (2)
AU (1)	AU2017361253B2 (2)
BR (1)	BR112019009880A2 (2)
CA (1)	CA3043617A1 (2)
CL (1)	CL2019001336A1 (2)
CO (1)	CO2019004945A2 (2)
CR (1)	CR20190239A (2)
DO (1)	DOP2019000118A (2)
EA (1)	EA038150B1 (2)
EC (1)	ECSP19034535A (2)
ES (1)	ES2952582T3 (2)
IL (1)	IL266547B (2)
JO (1)	JOP20190107A1 (2)
MA (1)	MA46855A (2)
MX (1)	MX389627B (2)
NI (1)	NI201900049A (2)
PE (1)	PE20191145A1 (2)
PH (1)	PH12019501079A1 (2)
RU (1)	RU2019115784A (2)
TN (1)	TN2019000149A1 (2)
UA (1)	UA125523C2 (2)
WO (1)	WO2018093949A1 (2)
ZA (1)	ZA201903099B (2)

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2017
- 2017-06-16 JO JOP/2019/0107A patent/JOP20190107A1/ar unknown
- 2017-11-15 TN TNP/2019/000149A patent/TN2019000149A1/en unknown
- 2017-11-15 KR KR1020197017201A patent/KR20190080935A/ko not_active Ceased
- 2017-11-15 AU AU2017361253A patent/AU2017361253B2/en not_active Ceased
- 2017-11-15 MX MX2019005773A patent/MX389627B/es unknown
- 2017-11-15 ES ES17871458T patent/ES2952582T3/es active Active
- 2017-11-15 EA EA201991029A patent/EA038150B1/ru unknown
- 2017-11-15 UA UAA201905617A patent/UA125523C2/uk unknown
- 2017-11-15 CR CR20190239A patent/CR20190239A/es unknown
- 2017-11-15 EP EP17871458.0A patent/EP3541820B1/en active Active
- 2017-11-15 BR BR112019009880A patent/BR112019009880A2/pt not_active IP Right Cessation
- 2017-11-15 US US16/349,047 patent/US11059822B2/en active Active
- 2017-11-15 WO PCT/US2017/061870 patent/WO2018093949A1/en not_active Ceased
- 2017-11-15 MA MA046855A patent/MA46855A/fr unknown
- 2017-11-15 RU RU2019115784A patent/RU2019115784A/ru unknown
- 2017-11-15 PE PE2019001017A patent/PE20191145A1/es unknown
- 2017-11-15 CA CA3043617A patent/CA3043617A1/en not_active Abandoned
- 2017-11-15 CN CN201780083651.3A patent/CN110267962B/zh active Active
- 2017-11-15 JP JP2019523671A patent/JP7042468B2/ja active Active
2019
- 2019-05-12 IL IL266547A patent/IL266547B/en unknown
- 2019-05-14 CO CONC2019/0004945A patent/CO2019004945A2/es unknown
- 2019-05-14 DO DO2019000118A patent/DOP2019000118A/es unknown
- 2019-05-15 PH PH12019501079A patent/PH12019501079A1/en unknown
- 2019-05-15 EC ECSENADI201934535A patent/ECSP19034535A/es unknown
- 2019-05-16 CL CL2019001336A patent/CL2019001336A1/es unknown
- 2019-05-16 NI NI201900049A patent/NI201900049A/es unknown
- 2019-05-17 ZA ZA2019/03099A patent/ZA201903099B/en unknown
2021
- 2021-06-09 US US17/343,227 patent/US11691975B2/en active Active

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Publication number	Publication date
PH12019501079A1 (en)	2019-08-19
ZA201903099B (en)	2021-01-27
CN110267962B (zh)	2022-04-01
EA201991029A1 (ru)	2019-12-30
AU2017361253B2 (en)	2021-08-05
US20200291023A1 (en)	2020-09-17
ECSP19034535A (es)	2019-05-31
IL266547A (en)	2019-07-31
KR20190080935A (ko)	2019-07-08
WO2018093949A1 (en)	2018-05-24
AU2017361253A1 (en)	2019-05-30
DOP2019000118A (es)	2019-09-30
UA125523C2 (uk)	2022-04-13
EP3541820C0 (en)	2023-07-05
IL266547B (en)	2022-06-01
NI201900049A (es)	2019-10-30
PE20191145A1 (es)	2019-09-02
CL2019001336A1 (es)	2019-10-04
US11059822B2 (en)	2021-07-13
JP2020500178A (ja)	2020-01-09
ES2952582T3 (es)	2023-11-02
EP3541820A4 (en)	2020-06-10
CO2019004945A2 (es)	2019-05-21
RU2019115784A (ru)	2020-12-17
NZ753471A (en)	2021-01-29
US20220135563A1 (en)	2022-05-05
MX389627B (es)	2025-03-20
CN110267962A (zh)	2019-09-20
TN2019000149A1 (en)	2020-10-05
EP3541820A1 (en)	2019-09-25
JOP20190107A1 (ar)	2019-05-09
EP3541820B1 (en)	2023-07-05
RU2019115784A3 (2)	2021-03-12
BR112019009880A2 (pt)	2019-08-13
EA038150B1 (ru)	2021-07-14
MX2019005773A (es)	2019-12-05
CR20190239A (es)	2019-06-26
JP7042468B2 (ja)	2022-03-28
MA46855A (fr)	2021-05-19
US11691975B2 (en)	2023-07-04

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2024-04-24	FZDE	Discontinued	Effective date: 20240228