CA3095628C - Benzofurane, benzopyrrole, benzothiophene substitues et inhibiteurs du complement structurellement apparentes - Google Patents

Benzofurane, benzopyrrole, benzothiophene substitues et inhibiteurs du complement structurellement apparentes

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Publication number
CA3095628C
CA3095628C CA3095628A CA3095628A CA3095628C CA 3095628 C CA3095628 C CA 3095628C CA 3095628 A CA3095628 A CA 3095628A CA 3095628 A CA3095628 A CA 3095628A CA 3095628 C CA3095628 C CA 3095628C
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Canada
Prior art keywords
alkyl
compound
phenyl
mmol
cycloalkyl
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Application number
CA3095628A
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English (en)
Other versions
CA3095628A1 (fr
Inventor
Pravin L. Kotian
Yarlagadda Babu
Weihe Zhang
Pen-Cheng Lu
Minwan Wu
Wei Lv
Trung Xuan Nguyen
Zhao Dang
Venkat R. Chintareddy
V. Satish Kumar
Krishnan Raman
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Biocryst Pharmaceuticals Inc
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Priority claimed from PCT/US2019/026054 external-priority patent/WO2019195720A1/fr
Publication of CA3095628A1 publication Critical patent/CA3095628A1/fr
Application granted granted Critical
Publication of CA3095628C publication Critical patent/CA3095628C/fr
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Abstract

L'invention concerne des composés de formules I et II, et des sels pharmaceutiquement acceptables et des promédicaments de ceux-ci, qui sont des inhibiteurs du système du complément. L'invention concerne également des compositions pharmaceutiques comprenant un tel composé, et des méthodes impliquant l'utilisation des composés et des compositions dans le traitement et la prévention de maladies et d'états pathologiques caractérisés par une activité aberrante du système du complément.
CA3095628A 2018-04-06 2019-04-05 Benzofurane, benzopyrrole, benzothiophene substitues et inhibiteurs du complement structurellement apparentes Active CA3095628C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862654108P 2018-04-06 2018-04-06
US62/654,108 2018-04-06
PCT/US2019/026054 WO2019195720A1 (fr) 2018-04-06 2019-04-05 Benzofurane, benzopyrrole, benzothiophène substitués et inhibiteurs du complément structurellement apparentés

Publications (2)

Publication Number Publication Date
CA3095628A1 CA3095628A1 (fr) 2019-10-10
CA3095628C true CA3095628C (fr) 2026-02-24

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