CH456622A - Procédé pour la récupération de plasminogène à partir de sérum sanguin animal ou de plasma sanguin animal et de préférence à partir de sang de porc - Google Patents

Procédé pour la récupération de plasminogène à partir de sérum sanguin animal ou de plasma sanguin animal et de préférence à partir de sang de porc

Info

Publication number: CH456622A
Authority: CH; Switzerland
Prior art keywords: plasminogen; serum; dilution; plasma; blood
Prior art date: 1962-12-10

Application number

CH1511563A

Other languages

English (en)

French (fr)

Inventor

Johannes Jensen Villy

Original Assignee

Novo Terapeutisk Labor As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1962-12-10

Filing date

1963-12-10

Publication date

1968-07-31

1962-12-10 Priority claimed from DK533962AA external-priority patent/DK100842C/da

1963-10-29 Priority claimed from DK509563A external-priority patent/DK102373C/da

1963-12-10 Application filed by Novo Terapeutisk Labor As filed Critical Novo Terapeutisk Labor As

1968-07-31 Publication of CH456622A publication Critical patent/CH456622A/fr

Links

210000002966 serum Anatomy 0.000 title claims description 25
210000002381 plasma Anatomy 0.000 title claims description 21
102000013566 Plasminogen Human genes 0.000 title claims description 19
108010051456 Plasminogen Proteins 0.000 title claims description 19
238000000034 method Methods 0.000 title claims description 13
241001465754 Metazoa Species 0.000 title claims description 9
238000011084 recovery Methods 0.000 title claims description 8
210000004369 blood Anatomy 0.000 title claims description 4
239000008280 blood Substances 0.000 title claims description 4
102000005686 Serum Globulins Human genes 0.000 claims description 14
108010045362 Serum Globulins Proteins 0.000 claims description 14
239000002244 precipitate Substances 0.000 claims description 12
238000001556 precipitation Methods 0.000 claims description 10
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 7
239000011148 porous material Substances 0.000 claims description 2
238000010790 dilution Methods 0.000 description 27
239000012895 dilution Substances 0.000 description 27
230000000694 effects Effects 0.000 description 21
108010088842 Fibrinolysin Proteins 0.000 description 19
229940012957 plasmin Drugs 0.000 description 19
239000005416 organic matter Substances 0.000 description 13
238000012360 testing method Methods 0.000 description 8
QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 6
QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 6
230000004913 activation Effects 0.000 description 4
239000012153 distilled water Substances 0.000 description 4
239000000243 solution Substances 0.000 description 4
239000007788 liquid Substances 0.000 description 3
239000000463 material Substances 0.000 description 3
230000001376 precipitating effect Effects 0.000 description 3
239000007858 starting material Substances 0.000 description 3
241000283690 Bos taurus Species 0.000 description 2
102000008946 Fibrinogen Human genes 0.000 description 2
108010049003 Fibrinogen Proteins 0.000 description 2
239000003085 diluting agent Substances 0.000 description 2
229940012952 fibrinogen Drugs 0.000 description 2
239000000203 mixture Substances 0.000 description 2
UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 1
102000009123 Fibrin Human genes 0.000 description 1
108010073385 Fibrin Proteins 0.000 description 1
BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 description 1
241001237728 Precis Species 0.000 description 1
239000003242 anti bacterial agent Substances 0.000 description 1
229940088710 antibiotic agent Drugs 0.000 description 1
210000000601 blood cell Anatomy 0.000 description 1
229910001628 calcium chloride Inorganic materials 0.000 description 1
239000001110 calcium chloride Substances 0.000 description 1
238000005119 centrifugation Methods 0.000 description 1
239000000701 coagulant Substances 0.000 description 1
238000007865 diluting Methods 0.000 description 1
230000008030 elimination Effects 0.000 description 1
238000003379 elimination reaction Methods 0.000 description 1
238000010828 elution Methods 0.000 description 1
238000002474 experimental method Methods 0.000 description 1
229950003499 fibrin Drugs 0.000 description 1
238000011835 investigation Methods 0.000 description 1
238000004519 manufacturing process Methods 0.000 description 1
239000011368 organic material Substances 0.000 description 1
238000012545 processing Methods 0.000 description 1
238000011160 research Methods 0.000 description 1
150000003839 salts Chemical class 0.000 description 1
238000000926 separation method Methods 0.000 description 1
239000007787 solid Substances 0.000 description 1
239000008399 tap water Substances 0.000 description 1
235000020679 tap water Nutrition 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6435—Plasmin (3.4.21.7), i.e. fibrinolysin
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
General Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Investigating Or Analysing Biological Materials (AREA)

CH1511563A 1962-12-10 1963-12-10 Procédé pour la récupération de plasminogène à partir de sérum sanguin animal ou de plasma sanguin animal et de préférence à partir de sang de porc CH456622A (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DK533962AA DK100842C (da)	1962-12-10	1962-12-10	Fremgangsmåde ved udvinding af plasminogen ud fra blodserum.
DK509563A DK102373C (da)	1963-10-29	1963-10-29	Fremgangsmåde ved udvinding af plasminogen.

Publications (1)

Publication Number	Publication Date
CH456622A true CH456622A (fr)	1968-07-31

Family

ID=26067737

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CH1511563A CH456622A (fr)	1962-12-10	1963-12-10	Procédé pour la récupération de plasminogène à partir de sérum sanguin animal ou de plasma sanguin animal et de préférence à partir de sang de porc

Country Status (3)

Country	Link
AT (1)	AT255026B (da)
CH (1)	CH456622A (da)
SE (1)	SE305718B (da)

1963
- 1963-12-09 SE SE1365063A patent/SE305718B/xx unknown
- 1963-12-10 CH CH1511563A patent/CH456622A/fr unknown
- 1963-12-10 AT AT989363A patent/AT255026B/de active

Also Published As

Publication number	Publication date
AT255026B (de)	1967-06-26
SE305718B (da)	1968-11-04

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