CH500947A - Procédé de préparation de l'acide N-propionyl-E-amino-caproïque et de ses sels - Google Patents

Procédé de préparation de l'acide N-propionyl-E-amino-caproïque et de ses sels

Info

Publication number: CH500947A
Authority: CH; Switzerland
Prior art keywords: propionyl; caproic acid; amino; salts; acid
Prior art date: 1968-05-03

Application number

CH670869A

Other languages

English (en)

French (fr)

Inventor

Choay Jean

Original Assignee

Biorec

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1968-05-03

Filing date

1969-05-01

Publication date

1970-12-31

1969-05-01 Application filed by Biorec filed Critical Biorec

1970-12-31 Publication of CH500947A publication Critical patent/CH500947A/fr

Links

229960002684 aminocaproic acid Drugs 0.000 title claims description 23
150000003839 salts Chemical class 0.000 claims abstract description 8
239000002253 acid Substances 0.000 claims description 6
238000000034 method Methods 0.000 claims description 5
230000002194 synthesizing effect Effects 0.000 claims description 4
159000000003 magnesium salts Chemical class 0.000 claims description 3
238000004519 manufacturing process Methods 0.000 claims description 3
WYVAMUWZEOHJOQ-UHFFFAOYSA-N propionic anhydride Chemical compound CCC(=O)OC(=O)CC WYVAMUWZEOHJOQ-UHFFFAOYSA-N 0.000 claims description 3
159000000000 sodium salts Chemical class 0.000 claims description 2
159000000007 calcium salts Chemical class 0.000 claims 1
239000000203 mixture Substances 0.000 abstract description 4
239000002537 cosmetic Substances 0.000 abstract description 3
230000015572 biosynthetic process Effects 0.000 abstract description 2
229910052791 calcium Inorganic materials 0.000 abstract description 2
229910052708 sodium Inorganic materials 0.000 abstract description 2
230000029663 wound healing Effects 0.000 abstract description 2
239000003795 chemical substances by application Substances 0.000 abstract 1
239000006071 cream Substances 0.000 abstract 1
239000006210 lotion Substances 0.000 abstract 1
238000011200 topical administration Methods 0.000 abstract 1
RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 22
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 7
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 7
CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 6
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 6
150000001875 compounds Chemical class 0.000 description 5
239000000843 powder Substances 0.000 description 4
238000007696 Kjeldahl method Methods 0.000 description 3
238000003321 atomic absorption spectrophotometry Methods 0.000 description 3
238000006243 chemical reaction Methods 0.000 description 3
238000002329 infrared spectrum Methods 0.000 description 3
VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 3
229910052757 nitrogen Inorganic materials 0.000 description 3
QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
JLVVSXFLKOJNIY-UHFFFAOYSA-N Magnesium ion Chemical compound [Mg+2] JLVVSXFLKOJNIY-UHFFFAOYSA-N 0.000 description 2
VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
FKNQFGJONOIPTF-UHFFFAOYSA-N Sodium cation Chemical compound [Na+] FKNQFGJONOIPTF-UHFFFAOYSA-N 0.000 description 2
238000003556 assay Methods 0.000 description 2
239000011575 calcium Substances 0.000 description 2
XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 description 2
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
229910001425 magnesium ion Inorganic materials 0.000 description 2
239000000155 melt Substances 0.000 description 2
238000002844 melting Methods 0.000 description 2
230000008018 melting Effects 0.000 description 2
239000002674 ointment Substances 0.000 description 2
239000003208 petroleum Substances 0.000 description 2
229910001415 sodium ion Inorganic materials 0.000 description 2
SLXKOJJOQWFEFD-UHFFFAOYSA-N 6-aminohexanoic acid Chemical compound NCCCCCC(O)=O SLXKOJJOQWFEFD-UHFFFAOYSA-N 0.000 description 1
ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 1
OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 1
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
101800000021 N-terminal protease Proteins 0.000 description 1
CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 1
XSTXAVWGXDQKEL-UHFFFAOYSA-N Trichloroethylene Chemical group ClC=C(Cl)Cl XSTXAVWGXDQKEL-UHFFFAOYSA-N 0.000 description 1
150000001408 amides Chemical group 0.000 description 1
229910021529 ammonia Inorganic materials 0.000 description 1
238000004458 analytical method Methods 0.000 description 1
229910001424 calcium ion Inorganic materials 0.000 description 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
238000004587 chromatography analysis Methods 0.000 description 1
229910052681 coesite Inorganic materials 0.000 description 1
210000002808 connective tissue Anatomy 0.000 description 1
238000001816 cooling Methods 0.000 description 1
229910052906 cristobalite Inorganic materials 0.000 description 1
239000013078 crystal Substances 0.000 description 1
238000010908 decantation Methods 0.000 description 1
210000004207 dermis Anatomy 0.000 description 1
230000008034 disappearance Effects 0.000 description 1
201000010099 disease Diseases 0.000 description 1
239000012153 distilled water Substances 0.000 description 1
239000008298 dragée Substances 0.000 description 1
210000002615 epidermis Anatomy 0.000 description 1
239000007972 injectable composition Substances 0.000 description 1
229910052740 iodine Inorganic materials 0.000 description 1
239000011630 iodine Substances 0.000 description 1
150000002500 ions Chemical class 0.000 description 1
239000011777 magnesium Substances 0.000 description 1
238000005259 measurement Methods 0.000 description 1
239000000825 pharmaceutical preparation Substances 0.000 description 1
229940127557 pharmaceutical product Drugs 0.000 description 1
KJFMBFZCATUALV-UHFFFAOYSA-N phenolphthalein Chemical compound C1=CC(O)=CC=C1C1(C=2C=CC(O)=CC=2)C2=CC=CC=C2C(=O)O1 KJFMBFZCATUALV-UHFFFAOYSA-N 0.000 description 1
238000002360 preparation method Methods 0.000 description 1
230000001737 promoting effect Effects 0.000 description 1
235000019260 propionic acid Nutrition 0.000 description 1
125000001501 propionyl group Chemical group O=C([*])C([H])([H])C([H])([H])[H] 0.000 description 1
IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 description 1
238000010992 reflux Methods 0.000 description 1
230000000717 retained effect Effects 0.000 description 1
239000000377 silicon dioxide Substances 0.000 description 1
235000012239 silicon dioxide Nutrition 0.000 description 1
210000003491 skin Anatomy 0.000 description 1
239000011734 sodium Substances 0.000 description 1
229910052682 stishovite Inorganic materials 0.000 description 1
239000000126 substance Substances 0.000 description 1
239000000829 suppository Substances 0.000 description 1
238000003786 synthesis reaction Methods 0.000 description 1
239000003826 tablet Substances 0.000 description 1
230000001225 therapeutic effect Effects 0.000 description 1
238000004448 titration Methods 0.000 description 1
238000000954 titration curve Methods 0.000 description 1
230000000699 topical effect Effects 0.000 description 1
229910052905 tridymite Inorganic materials 0.000 description 1
238000005406 washing Methods 0.000 description 1
230000037303 wrinkles Effects 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Birds (AREA)
Dermatology (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Cosmetics (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

CH670869A 1968-05-03 1969-05-01 Procédé de préparation de l'acide N-propionyl-E-amino-caproïque et de ses sels CH500947A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR150414		1968-05-03

Publications (1)

Publication Number	Publication Date
CH500947A true CH500947A (fr)	1970-12-31

Family

ID=8649757

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CH670869A CH500947A (fr)	1968-05-03	1969-05-01	Procédé de préparation de l'acide N-propionyl-E-amino-caproïque et de ses sels

Country Status (8)

Country	Link
JP (2)	JPS5331856B1 (de)
AT (2)	AT294797B (de)
CH (1)	CH500947A (de)
DK (1)	DK128650B (de)
ES (1)	ES366715A1 (de)
FR (1)	FR1583842A (de)
NL (1)	NL6906745A (de)
SE (2)	SE369073B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2765109B1 (fr) *	1997-06-25	2001-02-09	Seppic Sa	Composition comprenant un lipoaminoacide et les constituants d'un extrait de plantes riches en tanins et utilisation en cosmetique
DE112023001769T5 (de)	2022-07-01	2025-03-27	Mitsubishi Heavy Industries, Ltd.	Gasturbinenstatorschaufel und gasturbine

1968
- 1968-05-03 FR FR1583842D patent/FR1583842A/fr not_active Expired
1969
- 1969-04-29 SE SE608669A patent/SE369073B/xx unknown
- 1969-04-29 SE SE708972A patent/SE384133B/xx unknown
- 1969-05-01 DK DK241869A patent/DK128650B/da not_active IP Right Cessation
- 1969-05-01 CH CH670869A patent/CH500947A/fr not_active IP Right Cessation
- 1969-05-02 AT AT423469A patent/AT294797B/de not_active IP Right Cessation
- 1969-05-02 JP JP3447869A patent/JPS5331856B1/ja active Pending
- 1969-05-02 NL NL6906745A patent/NL6906745A/xx unknown
- 1969-05-02 ES ES366715A patent/ES366715A1/es not_active Expired
- 1969-05-02 AT AT213/71A patent/AT304765B/de not_active IP Right Cessation
- 1969-09-29 JP JP7810269A patent/JPS5022097B1/ja active Pending

Also Published As

Publication number	Publication date
FR1583842A (de)	1969-12-05
SE369073B (de)	1974-08-05
SE384133B (sv)	1976-04-26
AT304765B (de)	1972-12-15
JPS5022097B1 (de)	1975-07-28
ES366715A1 (es)	1971-03-16
NL6906745A (de)	1969-11-05
AT294797B (de)	1971-12-10
DK128650B (da)	1974-06-10
JPS5331856B1 (de)	1978-09-05

Legal Events

Date	Code	Title	Description
1982-01-29	PL	Patent ceased

Publication	Publication Date	Title
CA2024419C (fr)	1999-07-20	Nouveaux sels de metaux bivalents de l'acide n,n-di(carboxymethyl) amino-2cyano-3carboxymethyl-4 carboxy-5 thiophene, leur procede de preparation et les compositions pharmaceutiques les renfermant
CA1338561C (fr)	1996-08-27	Esters et thioesters aromatiques, leur procede de preparation et leur utilisation en medecine humaine ou veterinaire et en cosmetique
EP0260162B1 (de)	1990-11-14	Bizyklische aromatische Verbindungen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
EP0667330A1 (de)	1995-08-16	Cyclohexanol-derivate enthaltende mischungen als mittel zur übertragung eines angenehm kühlen gefühls, verfahren zur herstellung dieser derivate sowie benötigte zwischenprodukte
CA1294971C (fr)	1992-01-28	Derives benzofuranniques, leurs procedes de preparation et compositions medicamenteuse et cosmetique les contenant
MX2011011762A (es)	2012-10-05	Proceso para producir compuestos de p-mentano neo-enriquecidos.
CA1328465C (fr)	1994-04-12	Eicosanoides sulfures et leur application en pharmacie et en cosmetique
CA1312333C (fr)	1993-01-05	Sel de strontium, son procede de preparation et les compositions pharmaceutiques le renfermant
Cope et al.	1952	Cyclic Polyolefins. XX. Cycloöctatetraenecarboxylic Acid1
CH627648A5 (fr)	1982-01-29	Nouveaux derives de 20,21-dinoreburnamenine, procede de preparation et compositions pharmaceutiques.
CA1155438A (fr)	1983-10-18	Derives d'amino-14 steroides, et procede pour leur preparation
JPS5851944B2 (ja)	1983-11-19	フコウセイカゴウブツノセイホウ
EP0360637B1 (de)	1994-05-04	Benzofuranverbindungen, Verfahren zu ihrer Herstellung, diese enthaltende pharmazeutische und kosmetische Zusammenstellungen und Verwendung dieser Zusammenstellungen
CA1140155A (fr)	1983-01-25	PROCEDE DE PREPARATION D'UN NOUVEAU DERIVE DU 1.alpha.,25-DIHYDROXY CHOLECALCIFEROL
EP0279954B1 (de)	1993-03-17	Eicosattraynsäureamide, ihre Verwendung in der Arzneimittelkunde und Kosmetika, ihre Herstellung und Verfahren zur Herstellung von Eicosattraynsäure
CH646181A5 (fr)	1984-11-15	Procede de purification de l'acide ursodesoxycholique.
EP0082040B1 (de)	1986-01-15	3,7a-Diazacyclohepta(j,k)fluorenderivate, ihre Herstellung und ihre therapeutische Verwendung
CH299369A (fr)	1954-06-15	Procédé de préparation d'un nouveau produit à odeur ambrée.
JPH10182549A (ja)	1998-07-07	アルケニルサリチル酸の分離精製方法
Bhati	1962	Studies in the Sandalwood-Oil Series. I. The Structure, Synthesis, and Configuration of the Lactone of Tricycloekasantalic Acid1
CH334466A (fr)	1958-11-30	Procédé de préparation de nouveaux esters d'hormones corticosurrénales
JPS5822450B2 (ja)	1983-05-09	イソロンギホラン−３−オ−ル
HU184766B (en)	1984-10-29	Process for preparing 5-chloro-2-oxo-bicyclo/2,2,1/heptane-7-carboxylic acid alkyl esters
FR2889520A1 (fr)	2007-02-09	Procede de preparation de l'iriflophenone et utilisation en tant qu'agent antioxydant et antiradicalaire dans des compositions alimentaires, cosmetiques et pharmaceutiques le contenant
CH402842A (fr)	1965-11-30	Procédé de préparation de nouveaux dérivés de l'héparine