CH513111A - Verfahren zur Herstellung neuer Benz-epinderivate - Google Patents

Verfahren zur Herstellung neuer Benz-epinderivate

Info

Publication number
CH513111A
CH513111A CH136468A CH136468A CH513111A CH 513111 A CH513111 A CH 513111A CH 136468 A CH136468 A CH 136468A CH 136468 A CH136468 A CH 136468A CH 513111 A CH513111 A CH 513111A
Authority
CH
Switzerland
Prior art keywords
production
epine
benz
derivatives
new
Prior art date
Application number
CH136468A
Other languages
English (en)
Inventor
Karl-Heinz Dr Weber
Karl-Heinz Dr Hauptmann
Zeile Karl Dr Prof
Peter Dr Danneberg
Rolf Dr Giesemann
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Priority to CH791870A priority Critical patent/CH512502A/de
Priority to CH791970A priority patent/CH512429A/de
Publication of CH513111A publication Critical patent/CH513111A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH136468A 1967-02-01 1968-01-30 Verfahren zur Herstellung neuer Benz-epinderivate CH513111A (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CH791870A CH512502A (de) 1967-02-01 1968-01-30 Verfahren zur Herstellung neuer Benz-epinderivate
CH791970A CH512429A (de) 1967-02-01 1968-01-30 Verfahren zur Herstellung neuer Benz-epinderivate

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEB0090994 1967-02-01

Publications (1)

Publication Number Publication Date
CH513111A true CH513111A (de) 1971-09-30

Family

ID=6985591

Family Applications (1)

Application Number Title Priority Date Filing Date
CH136468A CH513111A (de) 1967-02-01 1968-01-30 Verfahren zur Herstellung neuer Benz-epinderivate

Country Status (4)

Country Link
CH (1) CH513111A (de)
DE (1) DE1593760A1 (de)
FR (2) FR1603343A (de)
GB (1) GB1211258A (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2353519A1 (fr) * 1975-12-08 1977-12-30 Roussel Uclaf Nouveaux derives de l'aminobenzocycloheptene et leurs sels, procede de preparation et application a titre de medicaments desdits produits
DE2931398A1 (de) * 1979-08-02 1981-02-26 Kali Chemie Pharma Gmbh Neue 1-benzoxepin-5(2h)-on-derivate und ihre salze, verfahren und zwischenprodukte zu deren herstellung und diese verbindungen enthaltende arzneimittel
DE2931399A1 (de) * 1979-08-02 1981-02-26 Kali Chemie Pharma Gmbh Neue 3-amino-1-benzoxepin-derivate und ihre salze, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
PH22343A (en) * 1983-02-15 1988-08-12 Merrell Dow Pharma 2h-(1) benzoxepino (5,4-b) 1,4-oxazine derivatives
PH21961A (en) * 1983-02-15 1988-04-15 Merrell Dow Pharma 2h-(1)benzoxepino(5,4-b)-1,4-oxazine derivative
DE3440296A1 (de) * 1984-11-05 1986-05-15 Kali-Chemie Pharma Gmbh, 3000 Hannover 3-amino-2,3-dihydro-1-benzoxepin-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4975461A (en) * 1986-06-19 1990-12-04 E. R. Squibb & Sons, Inc. P-aminophenols, derivatives thereof and method of use
AU597671B2 (en) * 1986-06-20 1990-06-07 Suntory Limited 2-Phenylbenzoxepin derivative
FR2698873B1 (fr) * 1992-12-07 1995-02-24 Lipha Benzocycloheptènes, benzoxépines et benzothiépines activateurs des canaux potassiques, procédé de préparation, composition pharmaceutique les contenant.
US6268392B1 (en) 1994-09-13 2001-07-31 G. D. Searle & Co. Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors
US5994391A (en) * 1994-09-13 1999-11-30 G.D. Searle And Company Benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
US6642268B2 (en) 1994-09-13 2003-11-04 G.D. Searle & Co. Combination therapy employing ileal bile acid transport inhibiting benzothipines and HMG Co-A reductase inhibitors
US6107494A (en) * 1994-09-13 2000-08-22 G.D. Searle And Company Substituted 5-aryl-benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
US6262277B1 (en) 1994-09-13 2001-07-17 G.D. Searle And Company Intermediates and processes for the preparation of benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
BR9508916A (pt) * 1994-09-13 1997-12-30 Monsanto Co "Novas benzotiepinas tendo atividade como inibidores de transporte do ácido biliar ileal e absorção de taurocolato"
EP1440972A1 (de) * 1996-03-11 2004-07-28 G.D. Searle & Co. Neue Benzothiepine mit pharmazeutischer Wirkung.
NZ331813A (en) * 1996-03-11 2001-03-30 G Benzothiepine compounds having activity as inhibitors of ileal bile acid transport and taurocholate uptake
AU723123B2 (en) * 1996-03-11 2000-08-17 G.D. Searle & Co. Novel benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
US6221897B1 (en) 1998-06-10 2001-04-24 Aventis Pharma Deutschland Gmbh Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use
DK1140184T3 (da) 1998-12-23 2003-09-29 Searle Llc Kombinationer af cholesterylestertransferproteinhæmmere og nikotinsyrederivater til hjertekar indikationer
DK1140185T3 (da) 1998-12-23 2003-09-29 Searle Llc Kombinationer af cholesterylestertransferhæmmere og galdesyre kompleksdannende forbindelser til hjertekar indikationer
EP1342475A1 (de) 1998-12-23 2003-09-10 G.D. Searle LLC. Kombinationen von Ileumgallensäuretransportinhibitoren und Cholesterylestertransferproteininhibitoren für kardiovaskuläre Indikationen
PT1140190E (pt) 1998-12-23 2003-02-28 Searle Llc Combinacoes de inibidores do transporte ileal dos acidos biliares e agentes sequestrantes dos acidos biliares usadas para problemas cardiovasculares
MXPA01006472A (es) 1998-12-23 2004-03-10 Searle Llc Combinaciones de inhibidores de transporte de acido biliar ileal y derivados de acido fibrico para indicaciones cardiovasculares.
AU2157400A (en) 1998-12-23 2000-07-31 G.D. Searle & Co. Combinations of cholesteryl ester transfer protein inhibitors and hmg coa reductase inhibitors for cardiovascular indications
EP1140186B1 (de) 1998-12-23 2003-06-04 G.D. Searle LLC. Kombinationen von cholesteryl ester transfer protein inhibitoren und fibronsäure derivaten für kardiovaskuläre indikationen
EP1286984A2 (de) 2000-03-10 2003-03-05 Pharmacia Corporation Verfahren zur herstellung von tetrahydrobenzothiepinen
US6740663B2 (en) 2001-11-02 2004-05-25 G.D. Searle, Llc Mono- and di-fluorinated benzothiepine compounds as inhibitors of apical sodium co-dependent bile acid transport (ASBT) and taurocholate uptake
AU2003207431A1 (en) 2002-01-17 2003-09-02 Pharmacia Corporation Novel alkyl/aryl hydroxy or keto thiepines.
KR102051031B1 (ko) 2011-10-28 2019-12-02 루메나 파마수티컬즈, 인코포레이티드 고담혈증 및 담즙 정체성 간 질환 치료용 담즙산 재순환 억제제
BR112014010223B8 (pt) 2011-10-28 2021-02-23 Lumena Pharmaceuticals Llc uso de uma composição compreendendo inibidores de reciclagem de ácido de bílis e forma de dosagem pediátrica

Also Published As

Publication number Publication date
FR8052M (de) 1970-06-29
FR1603343A (de) 1971-04-05
GB1211258A (en) 1970-11-04
DE1593760A1 (de) 1972-06-08

Similar Documents

Publication Publication Date Title
CH542853A (de) Verfahren zur Herstellung neuer Isothiocyano-benzazol-Derivate
AT293633B (de) Verfahren zur Herstellung neuer Halogenpregnadiene
CH526579A (de) Verfahren zur Herstellung neuer Benziodoxanderivate
CH474486A (de) Verfahren zur Herstellung neuer Diphenylharnstoffe
CH505805A (de) Verfahren zur Herstellung neuer Bisnorcholanderivate
AT279636B (de) Verfahren zur Herstellung neuer Benzomorphanderivate
CH519488A (de) Verfahren zur Herstellung neuer 19-Nor-androstatriene
CH476723A (de) Verfahren zur Herstellung neuer Isoindol-Derivate
CH492725A (de) Verfahren zur Herstellung neuer Chinazolinonderivate
CH517737A (de) Verfahren zur Herstellung neuer Spiro-azatetramethylen-Derivate
CH542228A (de) Verfahren zur Herstellung neuer Benzothiopyranopyridin-derivate
CH473807A (de) Verfahren zur Herstellung neuer 4-Hydroxy-chinoline
AT288607B (de) Verfahren zur Herstellung neuer Nebularin-Derivate
AT310961B (de) Verfahren zur Herstellung neuer 18-Methyl-5α-H-androstan-derivate
CH512502A (de) Verfahren zur Herstellung neuer Benz-epinderivate
AT283611B (de) Verfahren zur Herstellung neuer 3-Oxogonatrienderivate
AT295507B (de) Verfahren zur Herstellung neuer N,N-Diacylamine
AT266106B (de) Verfahren zur Herstellung neuer Nitrofuranderivate
CH509987A (de) Verfahren zur Herstellung neuer Benzolsulfonamide
CH487125A (de) Verfahren zur Herstellung neuer Cyanverbindungen
CH468386A (de) Verfahren zur Herstellung neuer Ergolen-Derivate
AT280502B (de) Verfahren zur Herstellung neuer 3-Oxogonatriene
AT286511B (de) Verfahren zur Herstellung neuer 4-Imino-19-nor-A-homo-steroid-triene
CH491110A (de) Verfahren zur Herstellung neuer Cassensäure-Derivate
CH491084A (de) Verfahren zur Herstellung neuer Cassensäure-Derivate

Legal Events

Date Code Title Description
PL Patent ceased