CH632343A5 - Process for the detection or for the determination of polyiodothyronines - Google Patents

Process for the detection or for the determination of polyiodothyronines Download PDF

Info

Publication number: CH632343A5
Authority: CH; Switzerland
Prior art keywords: enzyme; solution; usually; added; group
Prior art date: 1975-02-20

Application number

CH150976A

Other languages

German (de)

English (en)

Inventor

Judith I Blakemore

Richard K Leute

Roberta D Ernst

Original Assignee

Syva Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-02-20

Filing date

1976-02-09

Publication date

1982-09-30

1976-02-09 Application filed by Syva Co filed Critical Syva Co

1982-09-30 Publication of CH632343A5 publication Critical patent/CH632343A5/de

Links

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AEOCXXJPGCBFJA-UHFFFAOYSA-N ethionamide Chemical compound CCC1=CC(C(N)=S)=CC=N1 AEOCXXJPGCBFJA-UHFFFAOYSA-N 0.000 description 1
238000000605 extraction Methods 0.000 description 1
239000000706 filtrate Substances 0.000 description 1
238000001914 filtration Methods 0.000 description 1
239000011888 foil Substances 0.000 description 1
239000000499 gel Substances 0.000 description 1
239000008273 gelatin Substances 0.000 description 1
229920000159 gelatin Polymers 0.000 description 1
235000019322 gelatine Nutrition 0.000 description 1
235000011852 gelatine desserts Nutrition 0.000 description 1
238000002523 gelfiltration Methods 0.000 description 1
239000011521 glass Substances 0.000 description 1
ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 description 1
102000006602 glyceraldehyde-3-phosphate dehydrogenase Human genes 0.000 description 1
108020004445 glyceraldehyde-3-phosphate dehydrogenase Proteins 0.000 description 1
PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
239000010931 gold Substances 0.000 description 1
229910052737 gold Inorganic materials 0.000 description 1
230000036541 health Effects 0.000 description 1
229910001385 heavy metal Inorganic materials 0.000 description 1
108060003552 hemocyanin Proteins 0.000 description 1
150000002391 heterocyclic compounds Chemical class 0.000 description 1
GNOIPBMMFNIUFM-UHFFFAOYSA-N hexamethylphosphoric triamide Chemical compound CN(C)P(=O)(N(C)C)N(C)C GNOIPBMMFNIUFM-UHFFFAOYSA-N 0.000 description 1
150000002463 imidates Chemical class 0.000 description 1
239000000893 inhibin Substances 0.000 description 1
238000003780 insertion Methods 0.000 description 1
230000037431 insertion Effects 0.000 description 1
PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 description 1
150000002500 ions Chemical class 0.000 description 1
ZBKFYXZXZJPWNQ-UHFFFAOYSA-N isothiocyanate group Chemical group [N-]=C=S ZBKFYXZXZJPWNQ-UHFFFAOYSA-N 0.000 description 1
239000000463 material Substances 0.000 description 1
238000005259 measurement Methods 0.000 description 1
230000008986 metabolic interaction Effects 0.000 description 1
VNWKTOKETHGBQD-UHFFFAOYSA-N methane Natural products C VNWKTOKETHGBQD-UHFFFAOYSA-N 0.000 description 1
XELZGAJCZANUQH-UHFFFAOYSA-N methyl 1-acetylthieno[3,2-c]pyrazole-5-carboxylate Chemical compound CC(=O)N1N=CC2=C1C=C(C(=O)OC)S2 XELZGAJCZANUQH-UHFFFAOYSA-N 0.000 description 1
238000002156 mixing Methods 0.000 description 1
VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 1
239000012299 nitrogen atmosphere Substances 0.000 description 1
125000004433 nitrogen atom Chemical group N* 0.000 description 1
QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 description 1
125000005515 organic divalent group Chemical group 0.000 description 1
125000000962 organic group Chemical group 0.000 description 1
125000004430 oxygen atom Chemical group O* 0.000 description 1
125000000636 p-nitrophenyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1*)[N+]([O-])=O 0.000 description 1
ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
125000003356 phenylsulfanyl group Chemical group [*]SC1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 description 1
NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
239000004033 plastic Substances 0.000 description 1
229920003023 plastic Polymers 0.000 description 1
229920000573 polyethylene Polymers 0.000 description 1
239000000843 powder Substances 0.000 description 1
239000003755 preservative agent Substances 0.000 description 1
230000002335 preservative effect Effects 0.000 description 1
125000006239 protecting group Chemical group 0.000 description 1
238000003127 radioimmunoassay Methods 0.000 description 1
230000036632 reaction speed Effects 0.000 description 1
230000035484 reaction time Effects 0.000 description 1
238000010992 reflux Methods 0.000 description 1
125000006413 ring segment Chemical group 0.000 description 1
229920006395 saturated elastomer Polymers 0.000 description 1
235000019265 sodium DL-malate Nutrition 0.000 description 1
239000001394 sodium malate Substances 0.000 description 1
229910052938 sodium sulfate Inorganic materials 0.000 description 1
235000011152 sodium sulphate Nutrition 0.000 description 1
238000005476 soldering Methods 0.000 description 1
239000003381 stabilizer Substances 0.000 description 1
239000012258 stirred mixture Substances 0.000 description 1
239000011550 stock solution Substances 0.000 description 1
125000001424 substituent group Chemical group 0.000 description 1
239000004094 surface-active agent Substances 0.000 description 1
229960002175 thyroglobulin Drugs 0.000 description 1
238000004448 titration Methods 0.000 description 1
229940035722 triiodothyronine Drugs 0.000 description 1
150000003641 trioses Chemical class 0.000 description 1
238000000108 ultra-filtration Methods 0.000 description 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/78—Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Urology & Nephrology (AREA)
Hematology (AREA)
Biotechnology (AREA)
Analytical Chemistry (AREA)
Cell Biology (AREA)
Endocrinology (AREA)
Food Science & Technology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Microbiology (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Investigating Or Analysing Biological Materials (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

CH150976A 1975-02-20 1976-02-09 Process for the detection or for the determination of polyiodothyronines CH632343A5 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US55156675A	1975-02-20	1975-02-20

Publications (1)

Publication Number	Publication Date
CH632343A5 true CH632343A5 (en)	1982-09-30

Family

ID=24201792

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CH150976A CH632343A5 (en)	1975-02-20	1976-02-09	Process for the detection or for the determination of polyiodothyronines

Country Status (7)

Country	Link
JP (1)	JPS5924386B2 (it)
CA (1)	CA1028643A (it)
CH (1)	CH632343A5 (it)
DE (2)	DE2605162C2 (it)
FR (1)	FR2301823A1 (it)
GB (1)	GB1540728A (it)
IT (1)	IT1052946B (it)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4069105A (en) *	1977-03-03	1978-01-17	Syva Company	Lidocaine antigens and antibodies
IT1153999B (it) *	1977-03-15	1987-01-21	Snam Progetti	Composizione atta alla determinazione della triiodotironina e metodo diagnostico impiegante la stessa
US4156081A (en) *	1977-04-15	1979-05-22	Syva Company	Theophylline antigens and antibodies
GB2102946B (en) *	1981-06-30	1984-11-28	Wellcome Found	Enzyme immunoassay
EP0131096A2 (en) *	1983-05-02	1985-01-16	Miles Laboratories, Inc.	Homogeneous immunoassay method for determining binding substances and reagent system therefor
CA1317861C (en) *	1987-10-02	1993-05-18	Stephen B. Friedman	Homogeneous t-4 uptake assay
JP5465758B2 (ja)	2011-09-26	2014-04-09	富士フイルム株式会社	蛍光粒子を用いたサイロキシン免疫アッセイ
FR3146102B1 (fr)	2023-02-28	2025-01-10	Psa Automobiles Sa	Arrangement de recharge électrique pour véhicule automobile électrifié

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3551296A (en) *	1968-06-11	1970-12-29	Calbiochem	Reagent and method for assaying malate dehydrogenase
US3817837A (en)	1971-05-14	1974-06-18	Syva Corp	Enzyme amplification assay
IL39323A (en) *	1971-05-14	1975-08-31	Syva Co	Highly sensitive assay method employing an enzyme for amplification
US3852157A (en) *	1971-05-14	1974-12-03	Syva Corp	Compounds for enzyme amplification assay

1975
- 1975-12-30 CA CA242,815A patent/CA1028643A/en not_active Expired
1976
- 1976-01-07 GB GB54276A patent/GB1540728A/en not_active Expired
- 1976-01-19 IT IT4767776A patent/IT1052946B/it active
- 1976-01-23 FR FR7601919A patent/FR2301823A1/fr active Granted
- 1976-02-09 CH CH150976A patent/CH632343A5/de not_active IP Right Cessation
- 1976-02-10 DE DE19762605162 patent/DE2605162C2/de not_active Expired
- 1976-02-10 DE DE19762660911 patent/DE2660911C2/de not_active Expired
- 1976-02-16 JP JP1571476A patent/JPS5924386B2/ja not_active Expired

Also Published As

Publication number	Publication date
GB1540728A (en)	1979-02-14
JPS51106724A (ja)	1976-09-21
DE2660911C2 (de)	1986-05-28
DE2605162C2 (de)	1986-08-28
CA1028643A (en)	1978-03-28
FR2301823A1 (fr)	1976-09-17
DE2605162A1 (de)	1976-09-02
IT1052946B (it)	1981-08-31
JPS5924386B2 (ja)	1984-06-08
FR2301823B1 (it)	1980-05-23

Legal Events

Date	Code	Title	Description
2024-10-31	PL	Patent ceased

Publication	Publication Date	Title
DE2754086C3 (de)	1979-10-18	Spezifisches Bindungsverfahren zum Nachweis und zur Bestimmung eines Liganden in einem flüssigen Medium
DE2323467C2 (de)	1982-01-14	Verfahren zum Nachweis und zur Bestimmung von Haptenen
DE69423601T2 (de)	2000-07-06	Elektrochemische Bestimmungsmethode und neue p-Phenylendiamin-Verbindung
US4043872A (en)	1977-08-23	Polyiodothyronine immunoassay
DE2808476C2 (de)	1986-11-06	Reagens zur Verwendung in immunochemischen Untersuchungsmethoden
EP0397113B1 (de)	1993-11-18	Verfahren zum Nachweis spezifisch bindefähiger Substanzen in Körperflüssigkeiten
DE68926779T2 (de)	1996-11-14	Zusammensetzung und Methoden zur Bestimmung der Anwesenheit von Amphetaminen in einer Probe, die in Verdacht steht, Amphetamine und/oder Metamphetamine zu enthalten
DE69132055T2 (de)	2000-10-26	Ortsgenaue konjugatbildung zwischen immunglobulinen und nachweisbaren markierungsstoffen
DE60031570T2 (de)	2007-06-28	Immunoassay für neonicotinylinsektizide
EP0073514B1 (de)	1985-07-31	Creatinin-Antikörper
DE68910758T2 (de)	1994-05-26	Bestimmung mit Affinitätssubstanzen und HPLC-Schritt.
DE69433114T2 (de)	2004-07-08	Metallion-ligand koordinationskomplexe, antikorper dagegen und tests die solche antikorper verwenden
DE2155658A1 (de)	1972-05-18	Verfahren zum Nachweis und zur Bestimmung einer Komponente der Reaktion zwischen einer niedermolekularen Verbindung und einem Protein
DE2206103A1 (de)	1972-08-24	Verfahren zum Nachweisen und Bestimmen einer Komponente der Reaktion zwischen spezifisch bindenden Proteinen und den Substanzen, die von diesen Proteinen spezifisch gebunden werden
DE2830862C2 (it)	1988-06-01
DE2939165A1 (de)	1980-04-10	Cytotoxische produkte und verfahren zu ihrer herstellung
DE2910998A1 (de)	1979-10-04	Verfahren zur herstellung von gebundenes enzym enthaltenden produkten und deren verwendung
DE3004382A1 (de)	1980-08-14	Isotopen-doppeltest der schilddruesenfunktion
EP0451810B1 (de)	1995-08-16	Hapten-Biotin-Konjugate und ihre Verwendung
DE2805962A1 (de)	1978-09-07	Lidocain-antigene und antikoerper
US4171244A (en)	1979-10-16	Enzyme-bound-polyidothyronine
CH641570A5 (en)	1984-02-29	Process for the determination of an immunologically active material and reagent for carrying out this process
DE10048417A1 (de)	2002-04-11	Verbindungen mit verzweigtem Linker
EP0685070B1 (de)	2003-09-03	Acylierte proteinaggregate und deren verwendung zur entstörung von immunoassays
DE69409643T2 (de)	1998-08-06	Verfahren, agenzien und kits zum nachweis von phosphororganischen verbindungen