CH658070A5 - Lignee cellulaire derivee d'hybridomes humains, son procede de preparation et son utilisation pour la production d'anticorps humains monoclonaux. - Google Patents

Lignee cellulaire derivee d'hybridomes humains, son procede de preparation et son utilisation pour la production d'anticorps humains monoclonaux. Download PDF

Info

Publication number
CH658070A5
CH658070A5 CH7057/81A CH705781A CH658070A5 CH 658070 A5 CH658070 A5 CH 658070A5 CH 7057/81 A CH7057/81 A CH 7057/81A CH 705781 A CH705781 A CH 705781A CH 658070 A5 CH658070 A5 CH 658070A5
Authority
CH
Switzerland
Prior art keywords
cell
cell line
human
cells
myelomatic
Prior art date
Application number
CH7057/81A
Other languages
English (en)
French (fr)
Inventor
Carlo M Croce
Original Assignee
Wistar Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wistar Inst filed Critical Wistar Inst
Publication of CH658070A5 publication Critical patent/CH658070A5/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C12N5/163—Animal cells one of the fusion partners being a B or a T lymphocyte
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CH7057/81A 1980-11-07 1981-11-04 Lignee cellulaire derivee d'hybridomes humains, son procede de preparation et son utilisation pour la production d'anticorps humains monoclonaux. CH658070A5 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20483280A 1980-11-07 1980-11-07

Publications (1)

Publication Number Publication Date
CH658070A5 true CH658070A5 (fr) 1986-10-15

Family

ID=22759633

Family Applications (1)

Application Number Title Priority Date Filing Date
CH7057/81A CH658070A5 (fr) 1980-11-07 1981-11-04 Lignee cellulaire derivee d'hybridomes humains, son procede de preparation et son utilisation pour la production d'anticorps humains monoclonaux.

Country Status (12)

Country Link
JP (1) JPS57126424A (de)
AT (1) AT380898B (de)
AU (1) AU548738B2 (de)
BE (1) BE891003A (de)
CA (1) CA1198066A (de)
CH (1) CH658070A5 (de)
DE (1) DE3144181A1 (de)
FR (1) FR2493865A1 (de)
GB (1) GB2086937B (de)
IT (1) IT1140050B (de)
NZ (1) NZ198851A (de)
SE (1) SE460907B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1983002058A1 (en) * 1981-12-08 1983-06-23 Univ South Carolina Human monoclonal antibodies or lymphokines in separation of cells or diagnosis of mammary cancer
CA1247538A (en) * 1982-05-21 1988-12-28 Mark C. Glassy Human-human hybridomas for solid tumors
JPS58201994A (ja) * 1982-05-21 1983-11-25 Hideaki Hagiwara 抗原特異的ヒト免疫グロブリンの生産方法
US4618577A (en) * 1983-02-09 1986-10-21 The Regents Of The University Of California Human-human hybridoma, CLNH5
JPS58205773A (ja) * 1982-05-27 1983-11-30 Canon Inc インクジエツトプリンタ
EP0096839B1 (de) * 1982-06-09 1989-01-25 Asahi Kasei Kogyo Kabushiki Kaisha Verfahren zur Herstellung von menschlichen Antikörpern
US4744982A (en) * 1982-08-24 1988-05-17 Hunter Kenneth W Human monoclonal antibody reactive with polyribosylribitol phosphate
AU567693B2 (en) 1982-09-30 1987-12-03 University Of Rochester Human monoclonal antibodies against bacterial toxins
US4689299A (en) * 1982-09-30 1987-08-25 University Of Rochester Human monoclonal antibodies against bacterial toxins
IL70686A (en) * 1983-01-20 1988-07-31 Suntory Ltd Mutant tumor cell lines for use in the preparation of hybridomas and the hybridomas obtained therefrom
US4613576A (en) * 1983-03-09 1986-09-23 Sloan-Kettering Institute For Cancer Research Human monoclonal antibodies to cancer cells
US4693966A (en) * 1983-03-11 1987-09-15 Sloan-Kettering Institute For Cancer Research Human monoclonal antibodies from lymphocytes of patients with malignant melanoma
CA1218947A (en) * 1983-04-06 1987-03-10 Pearl M.J. Chen Human hybrid cell lines
JPS6133125A (ja) * 1984-07-25 1986-02-17 Morinaga & Co Ltd ヒト単クロ−ン性抗肺ガン細胞抗体
JPS61104796A (ja) * 1984-10-26 1986-05-23 Chemo Sero Therapeut Res Inst モノクロ−ナル抗体の製造方法
US4677070A (en) * 1985-04-26 1987-06-30 Cetus Corporation Pseudomonas aeruginosa exotoxin A antibodies, their preparation and use
EP0239102A3 (de) * 1986-03-28 1989-07-12 Tsuji, Kimiyoshi Verfahren zur Herstellung eines Human-Human-Hybridoms
AU3432389A (en) * 1988-04-07 1989-11-03 Farmitalia Carlo Erba S.R.L. Human monoclonal antibodies against rabies virus
CA2002067A1 (en) 1988-11-09 1990-05-09 Tamotsu Fukuda Parent cell line for producing human hybridomas
US5750106A (en) * 1993-01-28 1998-05-12 Novartis Ag Human monoclonal antibodies to cytomegalovirus

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4196265A (en) * 1977-06-15 1980-04-01 The Wistar Institute Method of producing antibodies
US4172124A (en) * 1978-04-28 1979-10-23 The Wistar Institute Method of producing tumor antibodies

Also Published As

Publication number Publication date
BE891003A (fr) 1982-03-01
GB2086937A (en) 1982-05-19
CA1198066A (en) 1985-12-17
IT8124862A0 (it) 1981-11-04
JPS57126424A (en) 1982-08-06
DE3144181A1 (de) 1982-09-09
AU7716781A (en) 1982-05-13
ATA476381A (de) 1985-12-15
SE8106528L (sv) 1982-05-08
IT1140050B (it) 1986-09-24
GB2086937B (en) 1985-05-30
NZ198851A (en) 1984-07-31
SE460907B (sv) 1989-12-04
AT380898B (de) 1986-07-25
FR2493865B1 (de) 1984-12-14
AU548738B2 (en) 1986-01-02
FR2493865A1 (fr) 1982-05-14

Similar Documents

Publication Publication Date Title
CH658070A5 (fr) Lignee cellulaire derivee d'hybridomes humains, son procede de preparation et son utilisation pour la production d'anticorps humains monoclonaux.
US4608337A (en) Human hybridomas and the production of human monoclonal antibodies by human hybridomas
FI75183C (fi) Foerfarande foer framstaellning av en komplement-bindande monoklonal antikropp mot maenniskans t-celler genom anvaendning av en ny hybridcellinje.
FI75364C (fi) Foerfarande foer framstaellning av en monoklonal antikropp foer maenskliga cytotoxiska och suppressor-t-celler medelst en ny hybridcellinje.
BE1000611A5 (fr) Anticorps monoclonaux et antigene du carcinome pulmonaire humain a cellules non petites et de certains autres carcinomes humains.
JPS5845407B2 (ja) 悪性腫瘍抗体の製造方法
JPH03236794A (ja) ヒトモノクローン抗体の製造法
JPH02227096A (ja) 抗体およびその製法
JPH0759518B2 (ja) 自己由来のワクチン
JP2002507398A (ja) ヒト・モノクローナル抗体およびそのための使用の開発
JPH0753110B2 (ja) 細胞産生物を取得する方法
FR2539759A1 (fr) Nouvelles lignees de cellules utilisables dans la preparation de cellules d'hybridome
EP0057107A2 (de) Verfahren zur Herstellung von monoklonalen Antikörpern und Zellen, fähig diese Antikörper herzustellen
WO2002046233A1 (fr) Procede de preparation d'un anticorps monoclonal humain, de fragments de celui-ci ou d'anticorps comprenant de tels fragments, les anticorps ainsi obtenus et leur utilisation
US4618585A (en) Hybridoma cell lines producing monoclonal antibodies directed against cervical cancer cells
EP0259807A2 (de) Komplementabhängiger zytolytischer monoklonaler Antikörper gegen Trichomonas vaginalis und seine therapeutische und diagnostische Verwendung
JP5058403B2 (ja) Ｃｋ−ｍｂ活性測定法およびｃｋ−ｍｂ活性測定試薬
JP4493882B2 (ja) 抗原およびこの抗原を識別するモノクローナル抗体
JPH05506241A (ja) ３５ｋｄ腫瘍関連タンパク質抗原および免疫複合体
JPS6115897A (ja) ヒト肝癌細胞を特異的に認識するモノクロ−ナル抗体
US4746612A (en) Aotus interspecies hybridomas and monoclonal receptors produced thereby
Price Hybridoma technology
JPH01124397A (ja) アスペルギルスに対するヒト・モノクローナル抗体とその製造法
FR2606034A1 (fr) Nouvelle proteine de surface des cellules basales de l'epiderme, anticorps capables de reconnaitre cette proteine, et leur utilisation, et lignees cellulaires hybrides capables de secreter de tels anticorps
JPS59187795A (ja) 抗アスペルギルス菌抗体

Legal Events

Date Code Title Description
PL Patent ceased
PL Patent ceased