CR20220418A - Compuestos tetracíclicos para el tratamiento de infecciones por vih - Google Patents

Compuestos tetracíclicos para el tratamiento de infecciones por vih

Info

Publication number
CR20220418A
CR20220418A CR20220418A CR20220418A CR20220418A CR 20220418 A CR20220418 A CR 20220418A CR 20220418 A CR20220418 A CR 20220418A CR 20220418 A CR20220418 A CR 20220418A CR 20220418 A CR20220418 A CR 20220418A
Authority
CR
Costa Rica
Prior art keywords
compounds
hiv infection
treating hiv
tetracyclic compounds
pharmaceutical compositions
Prior art date
Application number
CR20220418A
Other languages
English (en)
Inventor
Lan Jiang
David W Lin
Ezra Roberts
Michael L Mitchell
Gregg M Schwarzwalder
Original Assignee
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc
Publication of CR20220418A publication Critical patent/CR20220418A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

La presente divulgación se refiere en general a ciertos compuestos tetracíclicos, composiciones farmacéuticas que comprenden dichos compuestos y métodos para preparar dichos compuestos y composiciones farmacéuticas. Los compuestos de la divulgación son útiles para tratar o prevenir la infección por el virus de la inmunodeficiencia humana (VIH)
CR20220418A 2020-02-24 2021-02-23 Compuestos tetracíclicos para el tratamiento de infecciones por vih CR20220418A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US202062980857P 2020-02-24 2020-02-24
US202063036268P 2020-06-08 2020-06-08
US202063128670P 2020-12-21 2020-12-21
PCT/US2021/019179 WO2021173522A1 (en) 2020-02-24 2021-02-23 Tetracyclic compounds for treating hiv infection

Publications (1)

Publication Number Publication Date
CR20220418A true CR20220418A (es) 2022-10-10

Family

ID=74885056

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20220418A CR20220418A (es) 2020-02-24 2021-02-23 Compuestos tetracíclicos para el tratamiento de infecciones por vih

Country Status (15)

Country Link
US (2) US11697652B2 (es)
EP (1) EP4110783A1 (es)
JP (2) JP7453399B2 (es)
CN (1) CN115151545B (es)
AU (2) AU2021225809B2 (es)
BR (1) BR112022015771A2 (es)
CA (1) CA3166480A1 (es)
CO (1) CO2022011947A2 (es)
CR (1) CR20220418A (es)
DO (1) DOP2022000171A (es)
IL (1) IL295677B1 (es)
MX (1) MX2022009871A (es)
PE (1) PE20221569A1 (es)
TW (2) TW202248199A (es)
WO (1) WO2021173522A1 (es)

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MX2023009445A (es) 2021-02-16 2023-08-25 Merck Sharp & Dohme Llc Compuestos de heterociclos tetraciclicos utiles como inhibidores de la integrasa del vih.
TW202446773A (zh) 2022-04-06 2024-12-01 美商基利科學股份有限公司 橋聯三環胺甲醯基吡啶酮化合物及其用途

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