CL2007003781A1 - Metodo para la elaboracion de un conjugado inmunogenico que comprende el polisacarido del serotipo 1 de streptococcus pneumoniae covalentemente unido a una proteina vehiculo; y proceso para preparar una composicion inmunogenica multivalente polisacarido-proteina. - Google Patents

Metodo para la elaboracion de un conjugado inmunogenico que comprende el polisacarido del serotipo 1 de streptococcus pneumoniae covalentemente unido a una proteina vehiculo; y proceso para preparar una composicion inmunogenica multivalente polisacarido-proteina.

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Publication number
CL2007003781A1
CL2007003781A1 CL2007003781A CL2007003781A CL2007003781A1 CL 2007003781 A1 CL2007003781 A1 CL 2007003781A1 CL 2007003781 A CL2007003781 A CL 2007003781A CL 2007003781 A CL2007003781 A CL 2007003781A CL 2007003781 A1 CL2007003781 A1 CL 2007003781A1
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CL
Chile
Prior art keywords
polysaccharide
protein
preparing
preparation
covalently linked
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CL2007003781A
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English (en)
Inventor
William P Hausdorff
George Rainer Siber
Peter R Paradiso
A Krishna Prasad
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Application filed filed Critical
Publication of CL2007003781A1 publication Critical patent/CL2007003781A1/es

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/09Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092Streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/09Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/385Haptens or antigens, bound to carriers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6037Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
CL2007003781A 2006-12-22 2007-12-21 Metodo para la elaboracion de un conjugado inmunogenico que comprende el polisacarido del serotipo 1 de streptococcus pneumoniae covalentemente unido a una proteina vehiculo; y proceso para preparar una composicion inmunogenica multivalente polisacarido-proteina. CL2007003781A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11/644,207 US20070184072A1 (en) 2005-04-08 2006-12-22 Multivalent pneumococcal polysaccharide-protein conjugate composition

Publications (1)

Publication Number Publication Date
CL2007003781A1 true CL2007003781A1 (es) 2009-01-23

Family

ID=39386416

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2007003781A CL2007003781A1 (es) 2006-12-22 2007-12-21 Metodo para la elaboracion de un conjugado inmunogenico que comprende el polisacarido del serotipo 1 de streptococcus pneumoniae covalentemente unido a una proteina vehiculo; y proceso para preparar una composicion inmunogenica multivalente polisacarido-proteina.

Country Status (22)

Country Link
US (4) US20070184072A1 (es)
EP (1) EP2094304B1 (es)
JP (2) JP5815207B2 (es)
KR (3) KR20150129052A (es)
CN (2) CN105079800A (es)
AU (1) AU2007337214B9 (es)
BR (1) BRPI0721136B8 (es)
CA (1) CA2673558C (es)
CL (1) CL2007003781A1 (es)
DK (1) DK2094304T3 (es)
ES (1) ES2559060T3 (es)
HK (1) HK1215189A1 (es)
HU (1) HUE028421T2 (es)
IL (1) IL199324A (es)
MX (1) MX336934B (es)
PL (1) PL2094304T3 (es)
PT (1) PT2094304E (es)
RU (1) RU2484846C2 (es)
SG (1) SG177174A1 (es)
SI (1) SI2094304T1 (es)
WO (1) WO2008079653A1 (es)
ZA (1) ZA200904619B (es)

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