CL2017002206A1 - Composición inmunogénica multivalente que comprende 13 conjugados polisacarido capsular de un serotipo diferente de streptococcus pneumoniae-proteína junto con un vehículo aceptable y método para inducir una respuesta inmune a un conjugado de polisacarido (divisional de sol. n° 566-16). - Google Patents

Composición inmunogénica multivalente que comprende 13 conjugados polisacarido capsular de un serotipo diferente de streptococcus pneumoniae-proteína junto con un vehículo aceptable y método para inducir una respuesta inmune a un conjugado de polisacarido (divisional de sol. n° 566-16).

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Publication number
CL2017002206A1
CL2017002206A1 CL2017002206A CL2017002206A CL2017002206A1 CL 2017002206 A1 CL2017002206 A1 CL 2017002206A1 CL 2017002206 A CL2017002206 A CL 2017002206A CL 2017002206 A CL2017002206 A CL 2017002206A CL 2017002206 A1 CL2017002206 A1 CL 2017002206A1
Authority
CL
Chile
Prior art keywords
divisional
sun
inducing
immune response
immunogenic composition
Prior art date
Application number
CL2017002206A
Other languages
English (en)
Inventor
William P Hausdorff
George Rainer Siber
Peter R Paradiso
Original Assignee
Wyeth Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36709976&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2017002206(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Llc filed Critical Wyeth Llc
Publication of CL2017002206A1 publication Critical patent/CL2017002206A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
CL2017002206A 2005-04-08 2017-08-31 Composición inmunogénica multivalente que comprende 13 conjugados polisacarido capsular de un serotipo diferente de streptococcus pneumoniae-proteína junto con un vehículo aceptable y método para inducir una respuesta inmune a un conjugado de polisacarido (divisional de sol. n° 566-16). CL2017002206A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US66960505P 2005-04-08 2005-04-08

Publications (1)

Publication Number Publication Date
CL2017002206A1 true CL2017002206A1 (es) 2018-03-23

Family

ID=36709976

Family Applications (2)

Application Number Title Priority Date Filing Date
CL2016000566A CL2016000566A1 (es) 2005-04-08 2016-03-10 Método para para preparar una composición inmunogénica multivalente que comprende 13 conjugados de un serotipo diferente de streptococcus pneumoniae, donde cada uno de los conjugados contiene un polisacárido capsular diferente conjugado a la proteína portadora crm197. div. sol. madre n° 200600802 e hija cl 201702206.
CL2017002206A CL2017002206A1 (es) 2005-04-08 2017-08-31 Composición inmunogénica multivalente que comprende 13 conjugados polisacarido capsular de un serotipo diferente de streptococcus pneumoniae-proteína junto con un vehículo aceptable y método para inducir una respuesta inmune a un conjugado de polisacarido (divisional de sol. n° 566-16).

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CL2016000566A CL2016000566A1 (es) 2005-04-08 2016-03-10 Método para para preparar una composición inmunogénica multivalente que comprende 13 conjugados de un serotipo diferente de streptococcus pneumoniae, donde cada uno de los conjugados contiene un polisacárido capsular diferente conjugado a la proteína portadora crm197. div. sol. madre n° 200600802 e hija cl 201702206.

Country Status (29)

Country Link
US (9) US20060228380A1 (es)
EP (9) EP3311836A1 (es)
JP (3) JP4472770B2 (es)
KR (11) KR20150061019A (es)
CN (6) CN104815327A (es)
AR (2) AR053354A1 (es)
AT (1) ATE548051T1 (es)
AU (1) AU2006235013B2 (es)
BR (1) BRPI0607025B8 (es)
CA (4) CA2878579C (es)
CL (2) CL2016000566A1 (es)
CY (1) CY1112777T1 (es)
DK (1) DK1868645T3 (es)
ES (1) ES2382048T3 (es)
HK (1) HK1213184A1 (es)
HR (1) HRP20120278T1 (es)
IL (5) IL308456A (es)
ME (1) ME01334B (es)
MX (3) MX358148B (es)
MY (1) MY145150A (es)
NZ (1) NZ562406A (es)
PL (1) PL1868645T3 (es)
PT (1) PT1868645E (es)
RS (1) RS52249B (es)
SA (1) SA06270323B1 (es)
SI (1) SI1868645T1 (es)
TW (3) TWI511739B (es)
WO (1) WO2006110381A1 (es)
ZA (1) ZA200709483B (es)

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KR20140075196A (ko) 2012-12-11 2014-06-19 에스케이케미칼주식회사 다가 폐렴구균 다당류-단백질 접합체 조성물
CN110859957B (zh) 2014-01-21 2024-04-12 辉瑞公司 包含缀合荚膜糖抗原的免疫原性组合物及其用途
JP7680185B2 (ja) * 2017-02-24 2025-05-20 メルク・シャープ・アンド・ドーム・エルエルシー 肺炎連鎖球菌多糖－タンパク質コンジュゲートの免疫原性の増強

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