CL2008000249A1 - Uso de una molecula de acido nucleico que codifica al menos un polipeptido e2 del papilomavirus, un vector o una particula virica infecciosa que la comprenda para tratar una infeccion permanente por papilomavirus causada por al menos un papilomavirus - Google Patents

Uso de una molecula de acido nucleico que codifica al menos un polipeptido e2 del papilomavirus, un vector o una particula virica infecciosa que la comprenda para tratar una infeccion permanente por papilomavirus causada por al menos un papilomavirus

Info

Publication number
CL2008000249A1
CL2008000249A1 CL200800249A CL2008000249A CL2008000249A1 CL 2008000249 A1 CL2008000249 A1 CL 2008000249A1 CL 200800249 A CL200800249 A CL 200800249A CL 2008000249 A CL2008000249 A CL 2008000249A CL 2008000249 A1 CL2008000249 A1 CL 2008000249A1
Authority
CL
Chile
Prior art keywords
papilomavirus
papilom
viric
codifies
understands
Prior art date
Application number
CL200800249A
Other languages
English (en)
Spanish (es)
Inventor
Martine Balloul Jean-Ma Baudin
Original Assignee
Transgene Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Transgene Sa filed Critical Transgene Sa
Publication of CL2008000249A1 publication Critical patent/CL2008000249A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/20011Papillomaviridae
    • C12N2710/20022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CL200800249A 2007-01-30 2008-01-29 Uso de una molecula de acido nucleico que codifica al menos un polipeptido e2 del papilomavirus, un vector o una particula virica infecciosa que la comprenda para tratar una infeccion permanente por papilomavirus causada por al menos un papilomavirus CL2008000249A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07360004 2007-01-30
EP07360018 2007-05-15

Publications (1)

Publication Number Publication Date
CL2008000249A1 true CL2008000249A1 (es) 2008-05-30

Family

ID=39399907

Family Applications (1)

Application Number Title Priority Date Filing Date
CL200800249A CL2008000249A1 (es) 2007-01-30 2008-01-29 Uso de una molecula de acido nucleico que codifica al menos un polipeptido e2 del papilomavirus, un vector o una particula virica infecciosa que la comprenda para tratar una infeccion permanente por papilomavirus causada por al menos un papilomavirus

Country Status (20)

Country Link
US (1) US8420103B2 (fr)
EP (2) EP2118292B1 (fr)
JP (1) JP5474567B2 (fr)
KR (1) KR101636575B1 (fr)
CN (1) CN101617052A (fr)
AR (1) AR065076A1 (fr)
AT (1) ATE518958T1 (fr)
AU (1) AU2008209759B2 (fr)
BR (1) BRPI0806350A2 (fr)
CA (1) CA2675355C (fr)
CL (1) CL2008000249A1 (fr)
DK (1) DK2118292T3 (fr)
IL (2) IL199939A (fr)
MX (1) MX2009008118A (fr)
PE (1) PE20081723A1 (fr)
PL (1) PL2118292T3 (fr)
RU (2) RU2482189C2 (fr)
TW (1) TW200840869A (fr)
WO (1) WO2008092854A2 (fr)
ZA (1) ZA200904932B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0810305A2 (pt) * 2007-05-15 2018-07-10 Transgene Sa "vetor, molécula de ácido nucléico substancialmente isolada, célula hospedeira, composição farmacêutica, uso de uma molécula de ácido nucléico, uso de um vetor, uso de uma célula hospedeira e uso de uma composição"
EP2160402A2 (fr) * 2007-05-15 2010-03-10 Transgene SA Peptides de signalisation
KR20140076613A (ko) * 2011-10-12 2014-06-20 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 인간 파필로마 바이러스에 대한 백신 및 이것을 사용하는 방법
WO2014009433A1 (fr) 2012-07-10 2014-01-16 Transgene Sa Facteur de ressuscitation de mycobactéries convenant comme adjuvant
AU2014248535B2 (en) * 2013-03-12 2017-03-30 Inovio Pharmaceuticals, Inc. Improved vaccines for human papilloma virus and methods for using the same
WO2015149051A1 (fr) * 2014-03-28 2015-10-01 The Johns Hopkins University Schéma de traitement utilisant des vaccins contre le cancer et des adjuvants locaux et leur utilisation
AU2015341926B2 (en) * 2014-11-04 2018-09-27 Vidamune B.V. Therapeutic HPV16 vaccines
CN107847534B (zh) * 2015-04-17 2022-10-04 纪念斯隆凯特琳癌症中心 Mva或mvaδe3l作为抗实体瘤的免疫治疗剂的应用
EP3463577A4 (fr) * 2016-06-03 2019-12-04 Etubics Corporation Compositions et procédés de traitement de maladies associées au papillomavirus humain (pvh)
EP3518966A1 (fr) * 2016-09-29 2019-08-07 GlaxoSmithKline Biologicals S.A. Compositions et méthodes de traitement d'une infection par hpv persistante
JP7334124B2 (ja) 2017-06-21 2023-08-28 トランジェーヌ 個別化ワクチン
EP3461497A1 (fr) 2017-09-27 2019-04-03 GlaxoSmithKline Biologicals S.A. Antigènes viraux
US11012555B2 (en) 2017-11-20 2021-05-18 International Business Machines Corporation Non-verbal sensitive data authentication
EP3743436A4 (fr) * 2018-01-24 2021-10-27 The Council Of The Queensland Institute Of Medical Research Immunothérapie de l'hpv
KR102222582B1 (ko) * 2018-02-02 2021-03-04 주식회사 에스엘백시젠 신규 다가 hpv 백신 조성물
US12391746B2 (en) 2018-02-20 2025-08-19 Emory University HPV proteins, antibodies, and uses in managing abnormal epithelial cell growth
WO2019170820A1 (fr) 2018-03-07 2019-09-12 Transgene Vecteurs de parapoxvirus
JP7558167B2 (ja) 2018-12-03 2024-09-30 ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム オリゴベンズアミド類似体およびがん処置におけるそれらの使用
CN116200416B (zh) * 2023-02-15 2024-03-12 北京康乐卫士生物技术股份有限公司 一种基于Tac启动子的质粒表达载体构建及其用途
WO2025199501A1 (fr) * 2024-03-22 2025-09-25 Gritstone Bio, Inc. Vaccins contre le papillomavirus humain (hpv)

Family Cites Families (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4711955A (en) 1981-04-17 1987-12-08 Yale University Modified nucleotides and methods of preparing and using same
US4769330A (en) 1981-12-24 1988-09-06 Health Research, Incorporated Modified vaccinia virus and methods for making and using the same
US4603112A (en) 1981-12-24 1986-07-29 Health Research, Incorporated Modified vaccinia virus
CA1223831A (fr) 1982-06-23 1987-07-07 Dean Engelhardt Nucleotides modifies, methodes de preparation et d'utilisation et composes les contenant
FR2643817B1 (fr) 1989-03-06 1993-12-17 Transgene Sa Composition pharmaceutique, utile a titre preventif ou curatif contre les tumeurs induites par les papillomavirus
DE3642912A1 (de) 1986-12-16 1988-06-30 Leybold Ag Messeinrichtung fuer paramagnetische messgeraete mit einer messkammer
FR2632863B2 (fr) 1987-10-29 1990-08-31 Transgene Sa Virus du fowlpox recombinant et vaccins derives de ces virus
US5100587A (en) 1989-11-13 1992-03-31 The United States Of America As Represented By The Department Of Energy Solid-state radioluminescent zeolite-containing composition and light sources
US5756102A (en) 1990-11-20 1998-05-26 Virogenetics Corporation Poxvirus-canine distemper virus (CDV) recombinants and compositions and methods employing the recombinants
WO1992015672A1 (fr) 1991-03-07 1992-09-17 Virogenetics Corporation Souche de vaccin mise au point par genie genetique
GB9105383D0 (en) * 1991-03-14 1991-05-01 Immunology Ltd An immunotherapeutic for cervical cancer
US5179993A (en) 1991-03-26 1993-01-19 Hughes Aircraft Company Method of fabricating anisometric metal needles and birefringent suspension thereof in dielectric fluid
DE4123760C2 (de) 1991-07-18 2000-01-20 Dade Behring Marburg Gmbh Seroreaktive Bereiche auf den HPV 16 Proteinen E1 und E2
US6013638A (en) 1991-10-02 2000-01-11 The United States Of America As Represented By The Department Of Health And Human Services Adenovirus comprising deletions on the E1A, E1B and E3 regions for transfer of genes to the lung
GB9223084D0 (en) 1992-11-04 1992-12-16 Imp Cancer Res Tech Compounds to target cells
AU6014094A (en) * 1992-12-02 1994-06-22 Baylor College Of Medicine Episomal vectors for gene therapy
US6133028A (en) 1993-05-28 2000-10-17 Transgene S.A. Defective adenoviruses and corresponding complementation lines
FR2705686B1 (fr) 1993-05-28 1995-08-18 Transgene Sa Nouveaux adénovirus défectifs et lignées de complémentation correspondantes.
US5698443A (en) 1995-06-27 1997-12-16 Calydon, Inc. Tissue specific viral vectors
ATE328068T1 (de) * 1994-05-16 2006-06-15 Merck & Co Inc Papillomavirus vakzine
US5525711A (en) 1994-05-18 1996-06-11 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Pteridine nucleotide analogs as fluorescent DNA probes
US6638762B1 (en) 1994-11-28 2003-10-28 Genetic Therapy, Inc. Tissue-vectors specific replication and gene expression
US5998205A (en) 1994-11-28 1999-12-07 Genetic Therapy, Inc. Vectors for tissue-specific replication
FR2727689A1 (fr) 1994-12-01 1996-06-07 Transgene Sa Nouveau procede de preparation d'un vecteur viral
US5837520A (en) 1995-03-07 1998-11-17 Canji, Inc. Method of purification of viral vectors
FR2749323B1 (fr) * 1996-06-04 1998-07-10 Pasteur Merieux Serums Vacc Pseudo-particules virales utiles en tant que vecteur de delivrance d'acide nucleique
CZ438398A3 (cs) 1996-07-01 1999-03-17 Rhone-Poulenc Rorer S. A. Způsob přípravy rekombinantních adenovirů
WO1998022588A2 (fr) 1996-11-20 1998-05-28 Introgen Therapeutics, Inc. Procede ameliore pour production et purification de vecteurs d'adenovirus
ATE353956T1 (de) 1996-12-13 2007-03-15 Schering Corp Methoden zur virus-reinigung
WO1998056415A1 (fr) 1997-06-11 1998-12-17 Aquila Biopharmaceuticals, Inc. Saponines purifiees servant d'adjuvants oraux
FR2766091A1 (fr) * 1997-07-18 1999-01-22 Transgene Sa Composition antitumorale a base de polypeptide immunogene de localisation cellulaire modifiee
DE69806024T2 (de) 1997-09-16 2003-02-13 Delft Diagnostic Laboratory B.V., Delft Erkennung und identifizierung von menschlichem papillomavirus durch pcr und typ-spezifischer reverser hybridisierung
FR2774699B1 (fr) * 1997-11-17 2003-10-03 Rhone Poulenc Rorer Sa Methode de reduction des evenements de recombinaison homologue
FR2777570A1 (fr) 1998-04-17 1999-10-22 Transgene Sa Mutant ayant une activite phosphoribosyl transferase
JP3864610B2 (ja) 1998-05-21 2007-01-10 旭硝子株式会社 水分散型撥水撥油剤組成物およびその製造方法
US6900049B2 (en) 1998-09-10 2005-05-31 Cell Genesys, Inc. Adenovirus vectors containing cell status-specific response elements and methods of use thereof
US20020037274A1 (en) 1998-10-26 2002-03-28 Angelica Williams Single agent method for killing tumor and tumor associated endothelial cells using adenoviral mutants
US6582693B2 (en) * 1998-11-30 2003-06-24 Lemery, S.A. De C.V. Recombinant MVA virus expressing the E2 gene of Bovine papillomavirus and its use in the therapy of tumors generated by papillomaviruses
FR2787465A1 (fr) 1998-12-21 2000-06-23 Transgene Sa Procede d'inactivation des virus enveloppes dans une preparation virale de virus non enveloppes
HUP0104794A3 (en) 1998-12-31 2006-03-28 Centelion Method for separating viral particles
CA2362367C (fr) 1999-02-04 2004-08-03 Geron Corporation Sequences regulatoires transcriptionnelle de la transcriptase inversee de la telomerase
WO2000050573A1 (fr) 1999-02-22 2000-08-31 Transgene S.A. Procede d'obtention d'une preparation virale purifiee
US6492169B1 (en) 1999-05-18 2002-12-10 Crucell Holland, B.V. Complementing cell lines
ATE284898T1 (de) * 1999-08-25 2005-01-15 Merck & Co Inc Synthetische papillomavirus gene, welche für expression in menschlichen zellen optimiert sind
AU776061B2 (en) 1999-11-15 2004-08-26 Onyx Pharmaceuticals An oncolytic adenovirus
CA2341356C (fr) 2000-04-14 2011-10-11 Transgene S.A. Poxvirus specifique d'une infection ciblee
US20020029498A1 (en) * 2000-07-03 2002-03-14 Howard Harrison Rapid cool iron and related iron improvements
ATE346947T1 (de) 2000-07-21 2006-12-15 Glaxo Group Ltd Kodon-optimierte papillomavirussequenzen
WO2002096939A2 (fr) 2001-05-30 2002-12-05 Transgene S.A. Proteine d'adenovirus ix, ses domaines participant a l'ensemble de capside, activite transcriptionnelle et reorganisation nucleaire
WO2003018055A1 (fr) 2001-08-23 2003-03-06 Merck & Co., Inc. Vaccin mettant en oeuvre des proteines e du virus du papillome administrees par vecteur viral
PL218318B1 (pl) * 2002-05-16 2014-11-28 Bavarian Nordic As Rekombinowany wirus krowianki Ankara (MVA), zawierająca go komórka, szczepionka lub kompozycja farmaceutyczna, sposób lub zestaw do jego otrzymywania, sekwencja DNA zawierająca genom tego wirusa oraz sposób wykrywania tego wirusa lub komórek nim zainfekowanych
GB0222953D0 (en) * 2002-10-03 2002-11-13 Glaxo Group Ltd Novel Compounds
US20090028874A1 (en) * 2003-12-24 2009-01-29 Leiden University Medical Center Synthetic Protein as Tumor-Specific Vaccine
WO2005089164A2 (fr) 2003-12-31 2005-09-29 Pharmexa Inc. Induction de reponses immunitaires cellulaires au papillomavirus humain utilisant des compositions peptidiques et d'acides nucleiques

Also Published As

Publication number Publication date
CN101617052A (zh) 2009-12-30
DK2118292T3 (da) 2011-10-24
AU2008209759B2 (en) 2013-03-21
BRPI0806350A2 (pt) 2011-09-06
RU2013102035A (ru) 2014-07-27
US20100143408A1 (en) 2010-06-10
PL2118292T3 (pl) 2011-12-30
CA2675355A1 (fr) 2008-08-07
IL199939A0 (en) 2010-04-15
IL199939A (en) 2013-02-28
EP2118292B1 (fr) 2011-08-03
ATE518958T1 (de) 2011-08-15
PE20081723A1 (es) 2008-12-14
US8420103B2 (en) 2013-04-16
EP2118292A2 (fr) 2009-11-18
RU2009130791A (ru) 2011-03-10
JP5474567B2 (ja) 2014-04-16
IL215599A0 (en) 2011-11-30
EP2390340A2 (fr) 2011-11-30
JP2010516287A (ja) 2010-05-20
MX2009008118A (es) 2009-10-13
IL215599A (en) 2014-11-30
AU2008209759A1 (en) 2008-08-07
KR20090129399A (ko) 2009-12-16
CA2675355C (fr) 2015-04-28
TW200840869A (en) 2008-10-16
WO2008092854A2 (fr) 2008-08-07
RU2482189C2 (ru) 2013-05-20
EP2390340A3 (fr) 2012-02-22
ZA200904932B (en) 2010-04-28
AR065076A1 (es) 2009-05-13
KR101636575B1 (ko) 2016-07-05
WO2008092854A3 (fr) 2008-10-30

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