BRPI0912285A2 - anticorpos monoclonais tendo propriedades de neutralização cruzada de homosubtipo contra o vírus influenza subtipo h1. - Google Patents

anticorpos monoclonais tendo propriedades de neutralização cruzada de homosubtipo contra o vírus influenza subtipo h1.

Info

Publication number
BRPI0912285A2
BRPI0912285A2 BRPI0912285A BRPI0912285A BRPI0912285A2 BR PI0912285 A2 BRPI0912285 A2 BR PI0912285A2 BR PI0912285 A BRPI0912285 A BR PI0912285A BR PI0912285 A BRPI0912285 A BR PI0912285A BR PI0912285 A2 BRPI0912285 A2 BR PI0912285A2
Authority
BR
Brazil
Prior art keywords
monoclonal antibodies
influenza virus
properties against
subtype influenza
neutralizing properties
Prior art date
Application number
BRPI0912285A
Other languages
English (en)
Inventor
Massimo Clementi
Roberto Burioni
Original Assignee
Pomona Ricerca Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40303127&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0912285(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pomona Ricerca Srl filed Critical Pomona Ricerca Srl
Publication of BRPI0912285A2 publication Critical patent/BRPI0912285A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/108—Orthomyxoviridae (F), e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI0912285A 2008-05-27 2009-05-27 anticorpos monoclonais tendo propriedades de neutralização cruzada de homosubtipo contra o vírus influenza subtipo h1. BRPI0912285A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000398A ITTO20080398A1 (it) 2008-05-27 2008-05-27 Anticorpi monoclonali aventi proprieta' di cross-neutralizzazione omosubtipica per virus influenzali di tipo a sottotipo h1
PCT/IB2009/052212 WO2009144667A1 (en) 2008-05-27 2009-05-27 Monoclonal antibodies having homosubtype cross -neutralization properties against influenza a viruses subtype h1

Publications (1)

Publication Number Publication Date
BRPI0912285A2 true BRPI0912285A2 (pt) 2015-10-20

Family

ID=40303127

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0912285A BRPI0912285A2 (pt) 2008-05-27 2009-05-27 anticorpos monoclonais tendo propriedades de neutralização cruzada de homosubtipo contra o vírus influenza subtipo h1.

Country Status (17)

Country Link
US (1) US9243054B2 (pt)
EP (1) EP2294084B2 (pt)
JP (1) JP5792060B2 (pt)
KR (1) KR101665146B1 (pt)
CN (1) CN102124028B (pt)
AU (1) AU2009252758B2 (pt)
BR (1) BRPI0912285A2 (pt)
CA (1) CA2725627C (pt)
EA (1) EA022855B1 (pt)
ES (1) ES2555486T5 (pt)
IL (1) IL209499A (pt)
IT (1) ITTO20080398A1 (pt)
MX (1) MX2010012974A (pt)
NZ (1) NZ590115A (pt)
SG (1) SG191610A1 (pt)
WO (1) WO2009144667A1 (pt)
ZA (1) ZA201009273B (pt)

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ITTO20080204A1 (it) 2008-03-17 2009-09-18 Pomona Biotechnologies Llc Anticorpi monoclonali atti a reagire con una pluralita di sottotipi del virus influenzale a
ITTO20080398A1 (it) 2008-05-27 2009-11-28 Pomona Biotechnologies Llc Anticorpi monoclonali aventi proprieta' di cross-neutralizzazione omosubtipica per virus influenzali di tipo a sottotipo h1
ITTO20080964A1 (it) 2008-12-22 2010-06-23 Natimab Therapeutics S R L Anticorpo monoclonale anti-hcv come medicamento per il trattamento terapeutico e la prevenzione di infezioni da hcv
IT1395961B1 (it) * 2009-06-01 2012-11-02 Pomona Biotechnologies Llc Anticorpi monoclonali come medicamento per il trattamento terapeutico e/o profilattico delle infezioni da virus influenzale a (h1n1) di origine suina (s-oiv)
HRP20170490T1 (hr) * 2010-03-26 2017-06-02 Pomona Ricerca S.R.L. Imunoglobulini pune dužine igg izotipa sposobni za prepoznavanje heterosubtipnog epitopa neutralizacije na području stabljike hemaglutinina i njihova uporaba kao lijek protiv gripe
ITTO20110067A1 (it) * 2011-01-26 2012-07-27 Pomona Ricerca Srl Immunoglobuline intere di isotipo igg atte a riconoscere un epitopo di neutralizzazione eterosubtipica sulla regione stelo (stem region) dell'emoagglutinina e loro uso come medicamento antinfluenzale
CN102241768B (zh) * 2010-05-14 2013-12-25 中国科学院上海生命科学研究院 一种抗甲型h1n1流感病毒血凝素蛋白的抗体
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CN101988050B (zh) * 2010-12-09 2012-06-27 湖南出入境检验检疫局检验检疫技术中心 抗h1n1猪流感病毒血凝素蛋白单克隆抗体，杂交瘤细胞株及抗原捕获elisa试剂盒
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EP3699286A1 (en) 2011-04-20 2020-08-26 The Trustees of the University of Pennsylvania Regimens and compositions for aav-mediated passive immunization of airborne pathogens
US20150031571A1 (en) * 2012-02-07 2015-01-29 University Of Kansas Chemiluminescent nanoparticles and uses thereof
US9969794B2 (en) 2012-05-10 2018-05-15 Visterra, Inc. HA binding agents
SG11201602522VA (en) * 2013-10-02 2016-04-28 Medimmune Llc Neutralizing anti-influenza a antibodies and uses thereof
KR101628331B1 (ko) * 2014-03-28 2016-06-08 주식회사 녹십자엠에스 인플루엔자 a 바이러스 특이적 단클론 항체 및 이를 이용한 인플루엔자 감염 치료 및 진단 방법
CR20160519A (es) 2014-05-13 2017-01-27 The Trustees Of The Univ Of Pennysylvania Composiciones que comprenden avv que expresa constructos de anticuerpos duales y sus usos
WO2016011035A2 (en) 2014-07-15 2016-01-21 Medlmmune, Llc Neutralizing anti-influenza b antibodies and uses thereof
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WO2016200543A2 (en) 2015-05-13 2016-12-15 The Trustees Of The University Of Pennsylvania Aav-mediated expression of anti-inluenza antibodies and methods of use thereof
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RS65241B1 (sr) 2017-02-28 2024-03-29 Univ Pennsylvania Vektor adeno-asociranih virusa (aav) iz podgrupe f i njegove upotrebe
TW201837170A (zh) 2017-02-28 2018-10-16 賓州大學委員會 新穎ａａｖ媒介的流感疫苗
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AR124216A1 (es) 2020-12-01 2023-03-01 Univ Pennsylvania Composiciones nuevas con motivos selectivos específicos del tejido y composiciones que las contienen
JP2024515788A (ja) 2021-04-27 2024-04-10 ジェネレーション バイオ カンパニー 治療抗体を発現する非ウイルスｄｎａベクター及びその使用
EP4493212A1 (en) 2022-03-14 2025-01-22 Generation Bio Co. Heterologous prime boost vaccine compositions and methods of use
JP2026519488A (ja) * 2023-05-23 2026-06-16 ザ スクリプス リサーチ インスティテュート インフルエンザワクチン抗原としての安定化ヘマグルチニン（ｈａ）三量体
CN121021682B (zh) * 2025-10-29 2026-02-03 山东第一医科大学(山东省医学科学院) 一种抗甲型h1n1亚型猪流感病毒的重组纳米抗体及其制备方法和应用

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ITTO20080964A1 (it) 2008-12-22 2010-06-23 Natimab Therapeutics S R L Anticorpo monoclonale anti-hcv come medicamento per il trattamento terapeutico e la prevenzione di infezioni da hcv
IT1395961B1 (it) 2009-06-01 2012-11-02 Pomona Biotechnologies Llc Anticorpi monoclonali come medicamento per il trattamento terapeutico e/o profilattico delle infezioni da virus influenzale a (h1n1) di origine suina (s-oiv)
HRP20170490T1 (hr) 2010-03-26 2017-06-02 Pomona Ricerca S.R.L. Imunoglobulini pune dužine igg izotipa sposobni za prepoznavanje heterosubtipnog epitopa neutralizacije na području stabljike hemaglutinina i njihova uporaba kao lijek protiv gripe

Also Published As

Publication number Publication date
CN102124028A (zh) 2011-07-13
ES2555486T3 (es) 2016-01-04
JP2011524161A (ja) 2011-09-01
NZ590115A (en) 2012-08-31
EA201071365A1 (ru) 2011-08-30
EP2294084B2 (en) 2018-09-05
IL209499A0 (en) 2011-01-31
AU2009252758A1 (en) 2009-12-03
CN102124028B (zh) 2015-05-20
ES2555486T5 (es) 2019-02-15
US20110076265A1 (en) 2011-03-31
EP2294084A1 (en) 2011-03-16
ITTO20080398A1 (it) 2009-11-28
KR20110020865A (ko) 2011-03-03
EA022855B1 (ru) 2016-03-31
AU2009252758B2 (en) 2014-07-31
MX2010012974A (es) 2011-01-21
IL209499A (en) 2016-10-31
CA2725627C (en) 2019-08-06
US9243054B2 (en) 2016-01-26
EP2294084B1 (en) 2015-09-09
JP5792060B2 (ja) 2015-10-07
WO2009144667A1 (en) 2009-12-03
KR101665146B1 (ko) 2016-10-11
CA2725627A1 (en) 2009-12-03
ZA201009273B (en) 2012-05-01
SG191610A1 (en) 2013-07-31

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