CL2012002942A1 - Uso de un derivado sintetico de retinol e hidroxianisol butilado disuelto en aceite de soya para preparar un medicamento util en el tratamiento de un sujeto humano que sufre de la perdida o el deterioro de la vison causado por un trastorno por deficencia de retinol 11-cis producido endogenamente; composicion farmeceutica. - Google Patents

Uso de un derivado sintetico de retinol e hidroxianisol butilado disuelto en aceite de soya para preparar un medicamento util en el tratamiento de un sujeto humano que sufre de la perdida o el deterioro de la vison causado por un trastorno por deficencia de retinol 11-cis producido endogenamente; composicion farmeceutica.

Info

Publication number
CL2012002942A1
CL2012002942A1 CL2012002942A CL2012002942A CL2012002942A1 CL 2012002942 A1 CL2012002942 A1 CL 2012002942A1 CL 2012002942 A CL2012002942 A CL 2012002942A CL 2012002942 A CL2012002942 A CL 2012002942A CL 2012002942 A1 CL2012002942 A1 CL 2012002942A1
Authority
CL
Chile
Prior art keywords
retinol
deterioration
loss
prepare
dissolved
Prior art date
Application number
CL2012002942A
Other languages
English (en)
Inventor
H Andrew Strong
Suzanne Cadden
Original Assignee
Quadra Logic Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quadra Logic Tech Inc filed Critical Quadra Logic Tech Inc
Publication of CL2012002942A1 publication Critical patent/CL2012002942A1/es

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/11—Aldehydes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Método para tratar la pérdida o deterioro de la visión causado por un trastorno por deficiencia retinoide que comprende administrar una dosis terapéuticamente efectiva de un derivado sintético de retinol en reemplazo del retinol 11-CIS producido endógenamente, suspender el tratamiento por un mes y luego administrar una dosis adicional.
CL2012002942A 2010-04-19 2012-10-19 Uso de un derivado sintetico de retinol e hidroxianisol butilado disuelto en aceite de soya para preparar un medicamento util en el tratamiento de un sujeto humano que sufre de la perdida o el deterioro de la vison causado por un trastorno por deficencia de retinol 11-cis producido endogenamente; composicion farmeceutica. CL2012002942A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US32576310P 2010-04-19 2010-04-19
US40743610P 2010-10-27 2010-10-27
US201161447611P 2011-02-28 2011-02-28

Publications (1)

Publication Number Publication Date
CL2012002942A1 true CL2012002942A1 (es) 2013-04-12

Family

ID=44788663

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2012002942A CL2012002942A1 (es) 2010-04-19 2012-10-19 Uso de un derivado sintetico de retinol e hidroxianisol butilado disuelto en aceite de soya para preparar un medicamento util en el tratamiento de un sujeto humano que sufre de la perdida o el deterioro de la vison causado por un trastorno por deficencia de retinol 11-cis producido endogenamente; composicion farmeceutica.

Country Status (18)

Country Link
US (3) US9173856B2 (es)
EP (1) EP2563350B1 (es)
JP (4) JP6250389B2 (es)
KR (2) KR101851249B1 (es)
CN (2) CN107308143A (es)
AU (3) AU2011244024B2 (es)
BR (1) BR112012026939A2 (es)
CA (1) CA2796991A1 (es)
CL (1) CL2012002942A1 (es)
CO (1) CO6640227A2 (es)
HK (1) HK1246171A1 (es)
IL (1) IL222567A (es)
MX (1) MX339834B (es)
NO (1) NO20121362A1 (es)
NZ (1) NZ603331A (es)
RU (1) RU2622763C2 (es)
SG (2) SG10201507819VA (es)
WO (1) WO2011132084A2 (es)

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MX2012003220A (es) 2009-09-15 2012-08-03 Quadra Logic Tech Inc Formulaciones farmaceuticas que comprenden 9-cis-retinil esteres en un vehiculo de lipido.
KR101851249B1 (ko) 2010-04-19 2018-06-20 노벨리언 테라퓨틱스 인코포레이티드 내인성 레티노이드 결핍과 연관된 시각 장애의 치료 또는 완화를 위한 치료용 조성물, 제형 및 키트
KR102133608B1 (ko) * 2012-03-01 2020-07-13 레티나제닉스, 엘엘씨 내인성 레티노이드 결핍증과 관련된 시각 장애에서 시각 기능의 개선을 위한 치료 요법 및 방법
WO2015023902A2 (en) * 2013-08-14 2015-02-19 Qlt Inc. Therapeutic regimens and methods for improving visual function in visual disorders associated with impaired dark adaptation and/or impaired low luminance vision
KR102662879B1 (ko) 2017-09-29 2024-05-02 주식회사 툴젠 망막 기능장애 질환 치료를 위한 유전자 조작
CA3178762A1 (en) * 2020-06-09 2021-12-16 Eluminex Biosciences (Suzhou) Limited Methods of treating visual disorders using daily low dosing of a retinoid compound

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Also Published As

Publication number Publication date
JP2016014047A (ja) 2016-01-28
IL222567A0 (en) 2012-12-31
AU2017268684A1 (en) 2017-12-21
AU2011244024A1 (en) 2012-11-08
BR112012026939A2 (pt) 2016-07-12
NZ603331A (en) 2015-02-27
US9987245B2 (en) 2018-06-05
AU2011244024B2 (en) 2015-12-10
NO20121362A1 (no) 2012-11-19
EP2563350B1 (en) 2020-10-14
JP2017222721A (ja) 2017-12-21
WO2011132084A3 (en) 2012-02-16
MX2012012199A (es) 2013-02-11
SG184971A1 (en) 2012-11-29
SG10201507819VA (en) 2015-10-29
CO6640227A2 (es) 2013-03-22
US20170087114A1 (en) 2017-03-30
RU2622763C2 (ru) 2017-06-19
CN102939081A (zh) 2013-02-20
CA2796991A1 (en) 2011-10-27
MX339834B (es) 2016-06-14
KR101851249B1 (ko) 2018-06-20
US9173856B2 (en) 2015-11-03
JP2013527844A (ja) 2013-07-04
US20190029986A1 (en) 2019-01-31
AU2016201432A1 (en) 2016-03-24
IL222567A (en) 2017-06-29
CN107308143A (zh) 2017-11-03
KR20130054961A (ko) 2013-05-27
WO2011132084A2 (en) 2011-10-27
EP2563350A4 (en) 2013-09-18
US20110257266A1 (en) 2011-10-20
JP2019178162A (ja) 2019-10-17
RU2012148812A (ru) 2014-05-27
HK1246171A1 (zh) 2018-09-07
KR20180043846A (ko) 2018-04-30
JP6250389B2 (ja) 2017-12-20
EP2563350A2 (en) 2013-03-06

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