CL2013000813A1 - Dispositivo inmunocromatográfico que comprende una membrana que tiene un anticuerpo capaz de unirse a una proteina z-aat presente en una muestra de un portador del gen piz; metodo para determinar un portador del gen piz; metodo para diagnosticar una afección o enfermedad asociada con la deficiencia de aat; kits de inmunocromatografia - Google Patents

Dispositivo inmunocromatográfico que comprende una membrana que tiene un anticuerpo capaz de unirse a una proteina z-aat presente en una muestra de un portador del gen piz; metodo para determinar un portador del gen piz; metodo para diagnosticar una afección o enfermedad asociada con la deficiencia de aat; kits de inmunocromatografia

Info

Publication number
CL2013000813A1
CL2013000813A1 CL2013000813A CL2013000813A CL2013000813A1 CL 2013000813 A1 CL2013000813 A1 CL 2013000813A1 CL 2013000813 A CL2013000813 A CL 2013000813A CL 2013000813 A CL2013000813 A CL 2013000813A CL 2013000813 A1 CL2013000813 A1 CL 2013000813A1
Authority
CL
Chile
Prior art keywords
carrier
aat
piz gene
piz
diagnose
Prior art date
Application number
CL2013000813A
Other languages
English (en)
Inventor
Marco Grebe
Original Assignee
Grifols Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grifols Therapeutics Inc filed Critical Grifols Therapeutics Inc
Publication of CL2013000813A1 publication Critical patent/CL2013000813A1/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/38—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against protease inhibitors of peptide structure
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • G01N2333/811—Serine protease (E.C. 3.4.21) inhibitors
    • G01N2333/8121—Serpins
    • G01N2333/8125—Alpha-1-antitrypsin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CL2013000813A 2010-09-24 2013-03-22 Dispositivo inmunocromatográfico que comprende una membrana que tiene un anticuerpo capaz de unirse a una proteina z-aat presente en una muestra de un portador del gen piz; metodo para determinar un portador del gen piz; metodo para diagnosticar una afección o enfermedad asociada con la deficiencia de aat; kits de inmunocromatografia CL2013000813A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38621410P 2010-09-24 2010-09-24
US201161482867P 2011-05-05 2011-05-05

Publications (1)

Publication Number Publication Date
CL2013000813A1 true CL2013000813A1 (es) 2014-04-04

Family

ID=45874209

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2013000813A CL2013000813A1 (es) 2010-09-24 2013-03-22 Dispositivo inmunocromatográfico que comprende una membrana que tiene un anticuerpo capaz de unirse a una proteina z-aat presente en una muestra de un portador del gen piz; metodo para determinar un portador del gen piz; metodo para diagnosticar una afección o enfermedad asociada con la deficiencia de aat; kits de inmunocromatografia

Country Status (21)

Country Link
US (2) US9121857B2 (es)
EP (1) EP2619581B1 (es)
JP (1) JP5852657B2 (es)
KR (1) KR101753447B1 (es)
CN (1) CN103140758B (es)
AU (1) AU2011306651B2 (es)
BR (1) BR112013008602B1 (es)
CA (1) CA2811706C (es)
CL (1) CL2013000813A1 (es)
ES (1) ES2552649T3 (es)
HU (1) HUE025584T2 (es)
IL (1) IL225268A (es)
MX (1) MX346499B (es)
MY (1) MY172290A (es)
NZ (1) NZ609824A (es)
PL (1) PL2619581T3 (es)
PT (1) PT2619581E (es)
RU (1) RU2568875C2 (es)
SG (1) SG189060A1 (es)
WO (1) WO2012038820A2 (es)
ZA (1) ZA201302099B (es)

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WO2014159312A2 (en) * 2013-03-14 2014-10-02 University Of Florida Research Foundation, Incorporated A novel single chain antibody reduced mutant alpha-1 antitrypsin aggregation and toxicity
US20160077091A1 (en) * 2013-04-26 2016-03-17 Express Diagnostics International, Inc. Portable testing system for detecting selected drugs or compounds in noncontrolled environments
US20180306785A1 (en) * 2015-10-26 2018-10-25 Wellbeing Technologies Corp. Lateral flow assay devices and methods
US20170212112A1 (en) * 2016-01-25 2017-07-27 General Electric Company Integration of sample separation with rapid diagnostic tests for improved sensitivity
US10983119B2 (en) 2016-01-25 2021-04-20 General Electric Company Device for rapid diagnostic tests to detect antigens with improved sensitivity
EP3411716A1 (en) * 2016-02-03 2018-12-12 Nordic Bioscience A/S Combined biomarker measurement of fibrosis
EP3721229A4 (en) * 2017-12-05 2021-10-13 Becton, Dickinson and Company LATERAL FLOW ASSAY AND METHOD OF DETECTING HIGH CONCENTRATION ANALYTES
CN108931653A (zh) * 2018-08-31 2018-12-04 广州华澳生物科技有限公司 一种α1- 抗胰蛋白酶免疫层析检测试剂卡及其制备方法
US11884672B2 (en) 2019-05-14 2024-01-30 Vertex Pharmaceuticals Incorporated Modulators of alpha-1 antitrypsin
ES3038455T3 (en) * 2019-10-30 2025-10-13 Feral GmbH Lateral flow test arrangement suitable for detection of an analyte in saliva
AU2021247285A1 (en) 2020-04-03 2022-10-27 Vertex Pharmaceuticals Incorporated Modulators of alpha-1 antitrypsin
CN115697969B (zh) 2020-04-03 2026-08-11 弗特克斯药品有限公司 α-1抗胰蛋白酶调节剂
JP7732999B2 (ja) 2020-04-03 2025-09-02 バーテックス ファーマシューティカルズ インコーポレイテッド アルファ1-アンチトリプシンのモジュレーター
WO2021217062A1 (en) * 2020-04-24 2021-10-28 Kevin Fialko Sars-cov-2 susceptibility detection
EP4188931A2 (en) 2020-07-27 2023-06-07 Vertex Pharmaceuticals Incorporated Processes for preparing modulators of alpha-1 antitrypsin
WO2022104353A1 (en) 2020-11-12 2022-05-19 Vertex Pharmaceuticals Incorporated Methods of monitoring alpha-1 antitrypsin (aat) deficiency by measuring polymerised aat
FR3119023B1 (fr) * 2021-01-21 2024-11-08 Ng Biotech Système pour l’analyse rapide d’un échantillon de sang capillaire provenant d’un sujet, destiné à la détection de la présence d’au moins un analyte dans ledit échantillon de sang capillaire
CN113075396A (zh) * 2021-03-25 2021-07-06 江苏硕世生物科技股份有限公司 一种检测辅助装置
CN113791209B (zh) * 2021-08-12 2024-01-26 重庆工商大学 一种无钩状效应的免疫层析试纸条及制备方法
CN114100871A (zh) * 2021-11-21 2022-03-01 黄红 血液分离器具
WO2024059143A1 (en) * 2022-09-14 2024-03-21 Terumo Cardiovascular Systems Corporation Luminescent enzyme-based sensors

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8904007D0 (sv) * 1989-11-28 1989-11-28 Ferring Ab Monoklona antikroppar och diagnostiseringsmetod
JPH11201969A (ja) 1998-01-14 1999-07-30 Wakamoto Pharmaceut Co Ltd 簡易遊離ヘモグロビン測定方法および測定用キット
GB9919226D0 (en) * 1999-08-13 1999-10-20 Medical Res Council Allele detection
JP2004538453A (ja) * 2001-07-18 2004-12-24 スーリャン ゾー, 全細胞を含有するサンプルに対するラテラルフローアッセイのための試験片
US20030092090A1 (en) * 2001-11-14 2003-05-15 Kiamars Hajizadeh Rapid prion-detection device, system, and test kit
US20060246513A1 (en) 2005-05-02 2006-11-02 Bohannon Robert C Method and device to detect the presence of analytes in a sample
CN201203618Y (zh) * 2008-05-29 2009-03-04 重庆工学院 一种新城疫病毒免疫胶体金测试卡
JP5474784B2 (ja) 2008-06-30 2014-04-16 積水メディカル株式会社 結合アッセイ用多孔性固相及びこれを用いた結合アッセイ法
DE102009007616A1 (de) 2009-02-05 2010-08-12 Gaudlitz Gmbh Testvorrichtung für Flüssigkeiten des menschlichen oder tierischen Körpers

Also Published As

Publication number Publication date
MY172290A (en) 2019-11-20
BR112013008602A2 (pt) 2016-07-12
NZ609824A (en) 2014-10-31
CN103140758A (zh) 2013-06-05
US9921229B2 (en) 2018-03-20
EP2619581A4 (en) 2014-04-09
WO2012038820A2 (en) 2012-03-29
JP2013539029A (ja) 2013-10-17
HK1183514A1 (en) 2013-12-27
EP2619581A2 (en) 2013-07-31
ES2552649T3 (es) 2015-12-01
BR112013008602B1 (pt) 2020-11-17
PL2619581T3 (pl) 2016-02-29
RU2013118695A (ru) 2014-10-27
PT2619581E (pt) 2015-12-02
US9121857B2 (en) 2015-09-01
AU2011306651B2 (en) 2015-06-11
AU2011306651A1 (en) 2013-04-04
HUE025584T2 (en) 2016-04-28
CN103140758B (zh) 2015-03-11
CA2811706C (en) 2017-03-28
US20150323526A1 (en) 2015-11-12
KR101753447B1 (ko) 2017-07-03
EP2619581B1 (en) 2015-09-30
SG189060A1 (en) 2013-05-31
US20130183698A1 (en) 2013-07-18
WO2012038820A3 (en) 2012-08-02
KR20130115262A (ko) 2013-10-21
JP5852657B2 (ja) 2016-02-03
IL225268A (en) 2016-06-30
MX2013003161A (es) 2013-04-24
RU2568875C2 (ru) 2015-11-20
MX346499B (es) 2017-03-22
ZA201302099B (en) 2017-08-30
CA2811706A1 (en) 2012-03-29
IL225268A0 (en) 2013-06-27

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