CL2017001276A1 - Derivados de benzotiazol antibacterianos - Google Patents

Derivados de benzotiazol antibacterianos

Info

Publication number
CL2017001276A1
CL2017001276A1 CL2017001276A CL2017001276A CL2017001276A1 CL 2017001276 A1 CL2017001276 A1 CL 2017001276A1 CL 2017001276 A CL2017001276 A CL 2017001276A CL 2017001276 A CL2017001276 A CL 2017001276A CL 2017001276 A1 CL2017001276 A1 CL 2017001276A1
Authority
CL
Chile
Prior art keywords
benzothiazole derivatives
antibacterial
antibacterial benzothiazole
butanamida
benzotiazol
Prior art date
Application number
CL2017001276A
Other languages
English (en)
Inventor
Azely Mirre
Jean-Luc Specklin
Jean-Philippe Surivet
Christine Schmitt
Gaélle Chapoux
Original Assignee
Idorsia Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idorsia Pharmaceuticals Ltd filed Critical Idorsia Pharmaceuticals Ltd
Publication of CL2017001276A1 publication Critical patent/CL2017001276A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

<p>COMPUESTOS DERIVADOS DE BENZOTIAZOL BUTANAMIDA, COMPOSICIÓN FARMACÉUTICA QUE LOS CONTIENE Y SU USO EN LA PREVENCIÓN O EL TRATAMIENTO DE UNA INFECCIÓN BACTERIANA PRODUCIDA POR UNA BACTERIA GRAM-NEGATIVA</p>
CL2017001276A 2014-11-19 2017-05-18 Derivados de benzotiazol antibacterianos CL2017001276A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP2014075009 2014-11-19

Publications (1)

Publication Number Publication Date
CL2017001276A1 true CL2017001276A1 (es) 2018-02-16

Family

ID=54705241

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2017001276A CL2017001276A1 (es) 2014-11-19 2017-05-18 Derivados de benzotiazol antibacterianos

Country Status (19)

Country Link
US (1) US20170355687A1 (es)
EP (1) EP3221300B1 (es)
JP (1) JP2018500292A (es)
KR (1) KR20170086079A (es)
CN (1) CN107001300A (es)
AR (1) AR102687A1 (es)
AU (1) AU2015349005A1 (es)
BR (1) BR112017010474A2 (es)
CA (1) CA2963875A1 (es)
CL (1) CL2017001276A1 (es)
EA (1) EA031534B1 (es)
HK (1) HK1243411A1 (es)
IL (1) IL252269A0 (es)
MX (1) MX2017006413A (es)
PH (1) PH12017500907A1 (es)
SG (1) SG11201703992YA (es)
TW (1) TW201625569A (es)
UA (1) UA118722C2 (es)
WO (1) WO2016079688A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR105646A1 (es) * 2015-08-11 2017-10-25 Actelion Pharmaceuticals Ltd Agentes antibacterianos de 1,2-dihidro-3h-pirrolo[1,2-c]imidazol-3-ona sustituida
AR105848A1 (es) * 2015-08-31 2017-11-15 Actelion Pharmaceuticals Ltd Derivados heterocíclicos antibacterianos
AR105889A1 (es) 2015-09-03 2017-11-22 Actelion Pharmaceuticals Ltd Compuestos antibacterianos 1,2-dihidro-3h-pirrolo[1,2-c]imidazol-3-ona sustituidos
KR20190009324A (ko) * 2016-05-17 2019-01-28 이도르시아 파마슈티컬스 리미티드 6-(부타-1,3-디인-1-일)벤조[d]티아졸 유도체
JP7414282B2 (ja) 2017-12-07 2024-01-16 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン Ｎｓｄファミリー阻害物質及びそれによる治療の方法

Family Cites Families (19)

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JPS50121218A (es) * 1974-03-01 1975-09-23
JPH09118660A (ja) * 1995-04-10 1997-05-06 Takeda Chem Ind Ltd 芳香族ヒドロキサム酸誘導体、製造法および剤
GB9609794D0 (en) * 1996-05-10 1996-07-17 Smithkline Beecham Plc Novel compounds
US20040224952A1 (en) 2003-05-07 2004-11-11 Cowart Marlon D. Fused bicyclic-substituted amines as histamine-3 receptor ligands
WO2006063281A2 (en) 2004-12-10 2006-06-15 Emory University 2' and 3' - substituted cyclobutyl nucleoside analogs for the treatment of viral infections and abnormal cellular proliferation
DE102008044132A1 (de) 2008-11-27 2010-06-02 BSH Bosch und Siemens Hausgeräte GmbH Kältegerät mit zweiseitig anschlagbarer Tür
EP2432468A2 (en) 2009-05-20 2012-03-28 Ardea Biosciences, Inc. Methods of modulating uric acid levels
CA2774250C (en) * 2009-10-13 2013-12-17 Pfizer Inc. C-linked hydroxamic acid derivatives useful as antibacterial agents
PL2512474T3 (pl) 2009-12-16 2015-03-31 Pfizer N-przyłączone pochodne kwasu hydroksamowego użyteczne jako środki przeciwbakteryjne
AR083760A1 (es) 2010-11-10 2013-03-20 Achaogen Inc Agentes antibacterianos y composiciones farmaceuticas
US8853213B2 (en) 2011-01-03 2014-10-07 Hanmi Pharm. Co., Ltd Bicyclic compound for modulating G protein-coupled receptors
GEP20156370B (en) 2011-03-07 2015-09-25 Pfizer Fluoro-pyridinone derivatives useful as antibacterial agents
EP2694488B1 (en) 2011-04-08 2014-11-12 Pfizer Inc Isoxazole derivatives useful as antibacterial agents
EP2694481B1 (en) * 2011-04-08 2015-12-30 Pfizer Inc Imidazole, pyrazole, and triazole derivatives useful as antibacterial agents
WO2013170030A1 (en) 2012-05-09 2013-11-14 Achaogen, Inc. Antibacterial agents
EP2847168A1 (en) * 2012-05-10 2015-03-18 Achaogen, Inc. Antibacterial agents
WO2014165075A1 (en) 2013-03-12 2014-10-09 Achaogen, Inc. Antibacterial agents
AR097617A1 (es) 2013-09-13 2016-04-06 Actelion Pharmaceuticals Ltd Derivados antibacterianos del 2h-indazol
JP6407288B2 (ja) 2013-12-19 2018-10-17 イドーシア ファーマシューティカルズ リミテッドＩｄｏｒｓｉａ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ 抗菌性１ｈ−インダゾール及び１ｈ−インドール誘導体

Also Published As

Publication number Publication date
HK1243411A1 (zh) 2018-07-13
EA201791108A1 (ru) 2017-11-30
US20170355687A1 (en) 2017-12-14
IL252269A0 (en) 2017-07-31
WO2016079688A1 (en) 2016-05-26
JP2018500292A (ja) 2018-01-11
MX2017006413A (es) 2017-09-12
CA2963875A1 (en) 2016-05-26
UA118722C2 (uk) 2019-02-25
AR102687A1 (es) 2017-03-15
TW201625569A (zh) 2016-07-16
SG11201703992YA (en) 2017-06-29
PH12017500907A1 (en) 2017-11-27
AU2015349005A1 (en) 2017-07-06
EA031534B1 (ru) 2019-01-31
EP3221300A1 (en) 2017-09-27
KR20170086079A (ko) 2017-07-25
BR112017010474A2 (pt) 2017-12-26
EP3221300B1 (en) 2019-03-20
CN107001300A (zh) 2017-08-01

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