CL2018001844A1 - Método de preparación de isótopos - Google Patents
Método de preparación de isótoposInfo
- Publication number
- CL2018001844A1 CL2018001844A1 CL2018001844A CL2018001844A CL2018001844A1 CL 2018001844 A1 CL2018001844 A1 CL 2018001844A1 CL 2018001844 A CL2018001844 A CL 2018001844A CL 2018001844 A CL2018001844 A CL 2018001844A CL 2018001844 A1 CL2018001844 A1 CL 2018001844A1
- Authority
- CL
- Chile
- Prior art keywords
- solution
- exchange resin
- levigate
- strong
- acid
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
- B01D15/1871—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns placed in series
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
- B01D15/361—Ion-exchange
- B01D15/362—Cation-exchange
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
- B01D15/361—Ion-exchange
- B01D15/363—Anion-exchange
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
- B01J39/04—Processes using organic exchangers
- B01J39/05—Processes using organic exchangers in the strongly acidic form
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J41/00—Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
- B01J41/04—Processes using organic exchangers
- B01J41/05—Processes using organic exchangers in the strongly basic form
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J49/00—Regeneration or reactivation of ion-exchangers; Apparatus therefor
- B01J49/60—Cleaning or rinsing ion-exchange beds
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01F—COMPOUNDS OF THE METALS BERYLLIUM, MAGNESIUM, ALUMINIUM, CALCIUM, STRONTIUM, BARIUM, RADIUM, THORIUM, OR OF THE RARE-EARTH METALS
- C01F15/00—Compounds of thorium
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
- G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
- G21G1/001—Recovery of specific isotopes from irradiated targets
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- High Energy & Nuclear Physics (AREA)
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Optics & Photonics (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Geology (AREA)
- Inorganic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Medicinal Preparation (AREA)
- Indole Compounds (AREA)
Abstract
LA PRESENTE INVENCIÓN COMPRENDE UN MÉTODO PARA LA GENERACIÓN DE 227TH DE PUREZA FARMACÉUTICAMENTE TOLERABLE QUE COMPRENDE I) PREPARAR UNA MEZCLA GENERADORA QUE COMPRENDE 227AC, 227TH Y 223RA; II) CARGAR DICHA MEZCLA GENERADORA SOBRE UNA RESINA DE INTERCAMBIO ANIÓNICO DE BASE FUERTE; III) LEVIGAR UNA MEZCLA DE DICHOS 223RA Y 227AC DE DICHA RESINA DE INTERCAMBIO ANIÓNICO DE BASE FUERTE CON EL USO DE UN PRIMER ÁCIDO MINERAL EN UNA SOLUCIÓN ACUOSA; IV) LEVIGAR 227TH DE DICHA RESINA DE INTERCAMBIO ANIÓNICO DE BASE FUERTE CON EL USO DE UN SEGUNDO ÁCIDO MINERAL EN UNA SOLUCIÓN ACUOSA MEDIANTE LO CUAL SE GENERA UNA PRIMERA SOLUCIÓN DE 227TH QUE CONTIENE 223RA Y 227AC CONTAMINANTES; V) CARGAR LA PRIMERA SOLUCIÓN DE 227TH SOBRE UNA RESINA DE INTERCAMBIO CATIÓNICO DE ÁCIDO FUERTE; VI) LEVIGAR POR LO MENOS UNA PARTE DE LOS 223RA Y 227AC CONTAMINANTES DE DICHA RESINA DE INTERCAMBIO CATIÓNICO DE ÁCIDO FUERTE CON EL USO DE UN TERCER ÁCIDO MINERAL EN SOLUCIÓN ACUOSA; Y VII) LEVIGAR EL 227TH DE DICHA RESINA DE INTERCAMBIO CATIÓNICO DE ÁCIDO FUERTE CON EL USO DE UNA PRIMERA SOLUCIÓN DE TAMPÓN ACUOSA PARA PROPORCIONAR UNA SEGUNDA SOLUCIÓN DE 227TH. SE PROPORCIONAN ADEMÁS TORIO 227 PURIFICADO DE PUREZA FARMACÉUTICA Y UNA COMPOSICIÓN FARMACÉUTICA QUE LO COMPRENDE.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1600154.7A GB201600154D0 (en) | 2016-01-05 | 2016-01-05 | Isotope preparation method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2018001844A1 true CL2018001844A1 (es) | 2018-10-26 |
Family
ID=55406715
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2018001844A CL2018001844A1 (es) | 2016-01-05 | 2018-07-05 | Método de preparación de isótopos |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US20190009265A1 (es) |
| EP (1) | EP3400082A1 (es) |
| JP (1) | JP7017511B2 (es) |
| KR (1) | KR20180099705A (es) |
| CN (1) | CN108472555A (es) |
| AR (1) | AR107299A1 (es) |
| AU (1) | AU2016384271B2 (es) |
| BR (1) | BR112018013829A2 (es) |
| CA (1) | CA3010190C (es) |
| CL (1) | CL2018001844A1 (es) |
| CO (1) | CO2018007037A2 (es) |
| GB (1) | GB201600154D0 (es) |
| IL (1) | IL259644B (es) |
| MX (1) | MX2018008340A (es) |
| MY (1) | MY198655A (es) |
| PE (1) | PE20181454A1 (es) |
| RU (1) | RU2768732C2 (es) |
| SG (2) | SG10202006429YA (es) |
| TW (1) | TWI733732B (es) |
| UA (1) | UA125583C2 (es) |
| UY (1) | UY37066A (es) |
| WO (1) | WO2017118591A1 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3682959A1 (en) * | 2019-01-16 | 2020-07-22 | Sck Cen | Purification of actinium |
| KR102490805B1 (ko) * | 2019-07-02 | 2023-01-20 | 니혼 메디피직스 가부시키가이샤 | 226Ra 함유 용액의 정제 방법, 226Ra 타깃의 제조 방법, 및 225Ac의 제조 방법 |
| CN111398469B (zh) * | 2020-04-09 | 2020-10-27 | 中国科学院地质与地球物理研究所 | 一种小样品量的第四纪土壤碳酸盐的定年方法 |
| EP4260346A1 (en) * | 2020-12-10 | 2023-10-18 | Advanced Accelerator Applications | Method for producing high purity and high specific activity radionuclides |
| CN117051271B (zh) * | 2023-06-27 | 2026-02-10 | 国电投核素同创(重庆)科技有限公司 | 一种钍与散裂元素的分离方法 |
| WO2026008841A1 (en) * | 2024-07-05 | 2026-01-08 | Thor Medical Asa | Process for production of useful radionucleides |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5809394A (en) * | 1996-12-13 | 1998-09-15 | Battelle Memorial Institute | Methods of separating short half-life radionuclides from a mixture of radionuclides |
| NO310544B1 (no) * | 1999-01-04 | 2001-07-23 | Algeta As | Opparbeidelse og anvendelse av radium-223 til fremstilling av preparat samt kit til behandling av kalsifisert vev for palliasjon, benkreft-terapi og/eller overflatebehandling av ben |
| NO313180B1 (no) * | 2000-07-04 | 2002-08-26 | Anticancer Therapeutic Inv Sa | Bensökende alfapartikkel emitterende radiofarmasöytika |
| US20060228297A1 (en) * | 2003-04-15 | 2006-10-12 | Roy Larsen | Thorium-227 for use in radiotherapy of soft tissue disease |
| CA2522148C (en) * | 2003-04-15 | 2010-07-13 | Algeta As | Thorium-227 for use in radiotherapy of soft tissue disease |
| TWI372763B (en) * | 2005-06-17 | 2012-09-21 | Wyeth Llc | Methods of purifying anti a beta antibodies |
| GB201002508D0 (en) * | 2010-02-12 | 2010-03-31 | Algeta As | Product |
| GB201007354D0 (en) * | 2010-04-30 | 2010-06-16 | Algeta Asa | Method |
| GB201208309D0 (en) | 2012-05-11 | 2012-06-27 | Algeta As | Complexes |
| US9951399B2 (en) | 2014-04-09 | 2018-04-24 | Los Alamos National Security, Llc | Separation of protactinum, actinium, and other radionuclides from proton irradiated thorium target |
-
2016
- 2016-01-05 GB GBGB1600154.7A patent/GB201600154D0/en not_active Ceased
- 2016-12-29 CA CA3010190A patent/CA3010190C/en active Active
- 2016-12-29 EP EP16820307.3A patent/EP3400082A1/en not_active Withdrawn
- 2016-12-29 UA UAA201808336A patent/UA125583C2/uk unknown
- 2016-12-29 AU AU2016384271A patent/AU2016384271B2/en not_active Ceased
- 2016-12-29 US US16/067,146 patent/US20190009265A1/en not_active Abandoned
- 2016-12-29 KR KR1020187018798A patent/KR20180099705A/ko not_active Withdrawn
- 2016-12-29 WO PCT/EP2016/082835 patent/WO2017118591A1/en not_active Ceased
- 2016-12-29 BR BR112018013829A patent/BR112018013829A2/pt not_active IP Right Cessation
- 2016-12-29 PE PE2018001255A patent/PE20181454A1/es unknown
- 2016-12-29 MX MX2018008340A patent/MX2018008340A/es unknown
- 2016-12-29 IL IL259644A patent/IL259644B/en unknown
- 2016-12-29 SG SG10202006429YA patent/SG10202006429YA/en unknown
- 2016-12-29 JP JP2018535129A patent/JP7017511B2/ja not_active Expired - Fee Related
- 2016-12-29 CN CN201680077977.0A patent/CN108472555A/zh active Pending
- 2016-12-29 MY MYPI2018702317A patent/MY198655A/en unknown
- 2016-12-29 SG SG11201805459UA patent/SG11201805459UA/en unknown
- 2016-12-29 RU RU2018127822A patent/RU2768732C2/ru active
-
2017
- 2017-01-05 UY UY0001037066A patent/UY37066A/es not_active Application Discontinuation
- 2017-01-05 AR ARP170100023A patent/AR107299A1/es active IP Right Grant
- 2017-01-05 TW TW106100234A patent/TWI733732B/zh not_active IP Right Cessation
-
2018
- 2018-07-05 CO CONC2018/0007037A patent/CO2018007037A2/es unknown
- 2018-07-05 CL CL2018001844A patent/CL2018001844A1/es unknown
-
2020
- 2020-06-10 US US16/897,994 patent/US11452999B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| SG10202006429YA (en) | 2020-08-28 |
| IL259644B (en) | 2022-08-01 |
| CO2018007037A2 (es) | 2018-07-19 |
| BR112018013829A2 (pt) | 2018-12-11 |
| US20190009265A1 (en) | 2019-01-10 |
| TWI733732B (zh) | 2021-07-21 |
| RU2768732C2 (ru) | 2022-03-24 |
| KR20180099705A (ko) | 2018-09-05 |
| US11452999B2 (en) | 2022-09-27 |
| MX2018008340A (es) | 2018-09-17 |
| RU2018127822A3 (es) | 2020-03-17 |
| CA3010190C (en) | 2023-07-11 |
| CA3010190A1 (en) | 2017-07-13 |
| WO2017118591A1 (en) | 2017-07-13 |
| UY37066A (es) | 2017-08-31 |
| JP7017511B2 (ja) | 2022-02-08 |
| PE20181454A1 (es) | 2018-09-12 |
| AU2016384271B2 (en) | 2022-05-12 |
| AU2016384271A1 (en) | 2018-06-21 |
| GB201600154D0 (en) | 2016-02-17 |
| UA125583C2 (uk) | 2022-04-27 |
| AR107299A1 (es) | 2018-04-18 |
| TW201726586A (zh) | 2017-08-01 |
| MY198655A (en) | 2023-09-13 |
| RU2018127822A (ru) | 2020-02-06 |
| IL259644A (en) | 2018-07-31 |
| CN108472555A (zh) | 2018-08-31 |
| US20200406247A1 (en) | 2020-12-31 |
| SG11201805459UA (en) | 2018-07-30 |
| JP2019509467A (ja) | 2019-04-04 |
| EP3400082A1 (en) | 2018-11-14 |
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