CL2018002075A1 - Proceso de hidrogenación catalítico para preparar pirazoles - Google Patents

Proceso de hidrogenación catalítico para preparar pirazoles

Info

Publication number
CL2018002075A1
CL2018002075A1 CL2018002075A CL2018002075A CL2018002075A1 CL 2018002075 A1 CL2018002075 A1 CL 2018002075A1 CL 2018002075 A CL2018002075 A CL 2018002075A CL 2018002075 A CL2018002075 A CL 2018002075A CL 2018002075 A1 CL2018002075 A1 CL 2018002075A1
Authority
CL
Chile
Prior art keywords
catalytic hydrogenation
hydrogenation process
acids
pyrazoles
prepare
Prior art date
Application number
CL2018002075A
Other languages
English (en)
Inventor
Birgit Gockel
Eric George Klauber
Michael Rack
Sebastian Soergel
Roland Goetz
Original Assignee
Basf Se
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Se filed Critical Basf Se
Publication of CL2018002075A1 publication Critical patent/CL2018002075A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J21/00—Catalysts comprising the elements, oxides, or hydroxides of magnesium, boron, aluminium, carbon, silicon, titanium, zirconium, or hafnium
    • B01J21/18—Carbon
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
    • B01J23/40—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals of the platinum group metals
    • B01J23/42—Platinum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/16—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of hydrazones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/72—Hydrazones
    • C07C251/74—Hydrazones having doubly-bound carbon atoms of hydrazone groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C251/76—Hydrazones having doubly-bound carbon atoms of hydrazone groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of a saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

LA PRESENTE INVENCIÓN SE REFIERE A UN PROCESO CATALÍTICO PARA PREPARAR PIRAZOLES QUE COMPRENDE LA ETAPA DE CICLAR COMPUESTOS DE CARBONILO A,ß-INSATURADOS SUSTITUIDOS POR HIDRAZONA MEDIANTE SU REACCIÓN CON HIDRÓGENO EN UNA MEZCLA DE REACCIÓN QUE COMPRENDE COMO COMPONENTES (A) UN CATALIZADOR DE HIDROGENACIÓN, (B) UN ÁCIDO SELECCIONADO DE ÁCIDOS DE BRØNSTED, SALES DE AMONIO DE ÁCIDOS DE BRØNSTED Y ÁCIDOS DE LEWIS, (C) UN SOLVENTE PRÓTICO Y OPCIONALMENTE (D) UN SOLVENTE APRÓTICO.
CL2018002075A 2016-02-02 2018-08-02 Proceso de hidrogenación catalítico para preparar pirazoles CL2018002075A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP16153833 2016-02-02

Publications (1)

Publication Number Publication Date
CL2018002075A1 true CL2018002075A1 (es) 2018-09-14

Family

ID=55304873

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2018002075A CL2018002075A1 (es) 2016-02-02 2018-08-02 Proceso de hidrogenación catalítico para preparar pirazoles

Country Status (21)

Country Link
US (1) US10975036B2 (es)
EP (1) EP3411360B1 (es)
JP (1) JP6900400B2 (es)
KR (1) KR102651666B1 (es)
CN (1) CN108699003B (es)
AU (1) AU2017216082B2 (es)
BR (1) BR112018014357B8 (es)
CA (1) CA3010561C (es)
CL (1) CL2018002075A1 (es)
CO (1) CO2018008428A2 (es)
DK (1) DK3411360T3 (es)
ES (1) ES2795874T3 (es)
IL (1) IL260375B (es)
MX (1) MX384709B (es)
PE (1) PE20181539A1 (es)
PL (1) PL3411360T3 (es)
PT (1) PT3411360T (es)
RU (1) RU2733958C2 (es)
UA (1) UA124928C2 (es)
WO (1) WO2017133942A1 (es)
ZA (1) ZA201805742B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102531217B1 (ko) 2014-07-31 2023-05-10 바스프 에스이 피라졸의 제조 방법
WO2016180642A1 (en) 2015-05-08 2016-11-17 BASF Agro B.V. A process for the preparation of terpinolene epoxide
WO2016180614A1 (en) 2015-05-08 2016-11-17 Basf Se A process for the preparation of limonene-4-ol
PE20180327A1 (es) 2015-05-11 2018-02-13 Basf Se Proceso para preparar 4-amino-piridazinas
KR20190017924A (ko) 2016-06-15 2019-02-20 바스프 아그로 비.브이. 4치환 알켄의 에폭시화 방법
ES2877169T3 (es) 2016-06-15 2021-11-16 Basf Agro Bv Procedimiento para la epoxidación de un alqueno tetrasustituido
BR112018077104A2 (pt) 2016-07-07 2019-04-02 Basf Se compostos, processo para a preparação de compostos de fórmula i, processo para a preparação de compostos de fórmula iv e uso de compostos da fórmula i
ES2858699T3 (es) 2016-11-04 2021-09-30 Basf Se Procedimiento para la purificación de pirazolpiridazinas
US10538493B2 (en) 2016-11-17 2020-01-21 Basf Se Process for the purification of 1-(4-chlorophenyl)pyrazol-3-ol
WO2018137959A1 (en) 2017-01-25 2018-08-02 Basf Se Process for preparation of benzylic amides
US11261145B2 (en) 2017-03-20 2022-03-01 Basf Se Process for preparing bromotrichloromethane
US11358922B2 (en) 2017-11-02 2022-06-14 Basf Se Process for preparing 4-chlorobenzyl propargyl ether

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007326784A (ja) * 2006-06-06 2007-12-20 Sagami Chem Res Center １−置換−５−フルオロアルキルピラゾール−４−カルボン酸エステルの製造方法
CA2684950A1 (en) * 2007-04-20 2008-10-30 Deciphera Pharmaceuticals, Llc Kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases
US20110189167A1 (en) 2007-04-20 2011-08-04 Flynn Daniel L Methods and Compositions for the Treatment of Myeloproliferative Diseases and other Proliferative Diseases
AR068063A1 (es) 2007-08-27 2009-11-04 Basf Plant Science Gmbh Co mpuestos de pirazol para controlar plagas de invertebrados
WO2009068652A1 (en) * 2007-11-30 2009-06-04 Smithkline Beecham Corporation 2, 6-disubstituted pyridines and 2, 4-disubstituted pyrimidines as soluble guanylate cyclase activators
EP2288597B1 (de) * 2008-05-05 2014-10-29 Basf Se Verfahren zur herstellung von 1,3,4-substituierten pyrazolverbindungen
WO2010034738A2 (en) 2008-09-24 2010-04-01 Basf Se Pyrazole compounds for controlling invertebrate pests
WO2010034737A1 (en) 2008-09-24 2010-04-01 Basf Se Pyrazole compounds for controlling invertebrate pests
EP2236505A1 (de) 2009-04-03 2010-10-06 Bayer CropScience AG Acylierte Aminopyridine und - pyridazine als Insektizide
AR076984A1 (es) 2009-06-08 2011-07-20 Merck Serono Sa Derivados de pirazol oxadiazol
EP3498208A1 (en) 2011-04-12 2019-06-19 Thermedical, Inc. Devices for heating fluid in fluid enhanced ablation therapy
CN103492378B (zh) * 2011-04-21 2016-09-28 巴斯夫欧洲公司 杀虫吡唑化合物
JO3407B1 (ar) * 2012-05-31 2019-10-20 Eisai R&D Man Co Ltd مركبات رباعي هيدرو بيرازولو بيريميدين
EP2671873A1 (en) * 2012-06-06 2013-12-11 Solvay Sa Method for the cyclization of hydrazinoacrylic acid derivatives
WO2013189801A1 (en) * 2012-06-20 2013-12-27 Basf Se Pyrazole compound and pesticidal mixtures comprising a pyrazole compound
WO2014089364A1 (en) 2012-12-06 2014-06-12 Quanticel Pharmaceuticals, Inc Histone demethylase inhibitors
KR102531217B1 (ko) * 2014-07-31 2023-05-10 바스프 에스이 피라졸의 제조 방법
PE20180327A1 (es) 2015-05-11 2018-02-13 Basf Se Proceso para preparar 4-amino-piridazinas

Also Published As

Publication number Publication date
EP3411360A1 (en) 2018-12-12
PT3411360T (pt) 2020-06-01
US20190055200A1 (en) 2019-02-21
CA3010561A1 (en) 2017-08-10
PL3411360T3 (pl) 2020-08-24
WO2017133942A1 (en) 2017-08-10
PE20181539A1 (es) 2018-09-26
BR112018014357A2 (pt) 2018-12-18
RU2733958C2 (ru) 2020-10-08
AU2017216082B2 (en) 2020-12-03
RU2018130339A (ru) 2020-03-04
JP2019504883A (ja) 2019-02-21
CN108699003B (zh) 2023-02-03
KR102651666B1 (ko) 2024-03-26
AU2017216082A1 (en) 2018-07-26
ZA201805742B (en) 2019-11-27
MX384709B (es) 2025-03-14
UA124928C2 (uk) 2021-12-15
BR112018014357B1 (pt) 2022-08-16
CN108699003A (zh) 2018-10-23
CO2018008428A2 (es) 2018-08-21
IL260375B (en) 2021-03-25
CA3010561C (en) 2024-04-16
JP6900400B2 (ja) 2021-07-07
RU2018130339A3 (es) 2020-03-19
BR112018014357B8 (pt) 2022-09-06
DK3411360T3 (da) 2020-06-08
MX2018009453A (es) 2018-09-21
KR20180104743A (ko) 2018-09-21
EP3411360B1 (en) 2020-03-11
US10975036B2 (en) 2021-04-13
ES2795874T3 (es) 2020-11-25

Similar Documents

Publication Publication Date Title
CO2018008428A2 (es) Proceso de hidrogenación catalítico para preparar pirazoles
CL2016003324A1 (es) Construcciones de anticuerpos multiespecificos.
MX384713B (es) Proceso para preparar terpinen-4-ol.
CU24466B1 (es) Compuestos derivados de d-fenilalanina-n-sustituido con biciclos aromáticos, método de preparación de las mismas y composiciones farmacéuticas que los contienen
MX2014009271A (es) Procedimiento para la preparacion de un material zeolitico.
MX2018010304A (es) Proceso para preparar una mezcla de alcoholes de terpeno.
PH12015501960A1 (en) Processes for the preparation of an apoptosis-inducing agent
CL2016000919A1 (es) Método para preparar un portador esférico de un catalizador para la polimerización de olefinas; portador esférico; proceso para preparar una composición solida; composición solida; componente catalizador; método para preparar un componente catalizador; catalizador para la polimerización de olefinas; uso del catalizador; y método para la polimerización de olefina(s).
MX392317B (es) Proceso para la preparación de etilenglicol a partir de azúcares.
CR20170590A (es) Nuevos derivados hidroxiácido, un proceso para su preparación y composiciones farmacéuticas que los contienen
CY1121304T1 (el) Μεθοδος καθαρισμου σαπωνινων
BR112018010229A2 (pt) sistema catalisador e processo para a produção de glicóis
MX373623B (es) Catalizadores de rutenio-fenol para reacciones de hidrogenación por trasferencia.
MX2020004869A (es) Metodo para preparar derivado de benzofurano.
MX2017000023A (es) Proceso para preparar fenilalcanos sustituidos.
BR112017006552A2 (pt) composições e métodos para inibir a atividade biológica de biomoléculas solúveis
MX2016006976A (es) Proceso para la preparacion de 5-fluoro-1h-pirazoles.
MX384794B (es) Proceso para la preparacion de 5-fluoro-1h-pirazoles a partir de hexafluoropropeno.
MX2016000390A (es) Proceso para fabricar haloacetamidas.
CL2016002515A1 (es) Quinazolin-thf-aminas halogenadas como inhibidores de pde1.
MX387903B (es) Proceso para la preparacion de acidos 3-hidroxipicolinicos.
CL2017002255A1 (es) Procesos para preparar fluorocetólidos.
MX386134B (es) Proceso para la preparación de 5-fluoro-1h-pirazoles.
AR102980A1 (es) Un proceso para la fabricación de idalopirdina
CL2016002303A1 (es) Compuestos químicos.